Dra. Leonor Perez Martinez
Investigador
Neurobiología Celular y Molecular
Neuroinmunobiología
Número de registros: 11
- Activos
- Vencidos
- La neuroinflamación y la enfermedad de alzheimer: el papel de kchip3, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2019 - 2021
- La respuesta antiviral es responsable de la microcefalia inducida por el virus del zika: la función de los factores reguladores del interferón en la inhibición de la diferenciación neuronal, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2017 - 2021
- Impacto del ambiente enriquecido en la neurogénesis hipotalámica y la regulación del balance energético, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2016 - 2019
- Estudio de los mecanismos moleculares que activan y regulan el proceso inflamatorio en el sistema nervioso central, PRESUPUESTO UNAM, 2014 - 2020
- El papel de los micrornas en la diferenciación de fenotipos neuronales hipotalámicos durante el desarrollo embrionario del ratón, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2012 - 2015
- Participación del factor de transcripción klf10 en el desarrollo y funcionamiento del hipotálamo, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2012 - 2014
- Participación de los factores de transcripción klf4 y klf10 en la diferenciación neuronal durante el desarrollo del hipotalamo, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2009 - 2011
- Señales que regulan el splicin alternativo del gen de la piroglutamil peptidasa ii, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2009
- El papel del tgfbeta y el factor de transcripción tie1i en el establecimiento del fenotipo trhérgico, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2007 - 2010
- El factor de transcripción klf4 y el establecimiento del fenotipo trhérgico en el hipotálamo fetal., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2006 - 2008
- Desarrollo terminal del metabolismo y fenotipo trhergico en el hipotálamo de roedor. papel de factores tróficos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2000 - 2001
Nivel C del PRIDE
Nivel II del SNI
Nivel II del SNI
Doctorado, Biología Celular, Instituto Friedrich Miescher, Basilea
Maestría, en Ciencias, Instituto Weizmann de Ciencia, Israel (1988)
Licenciatura, Biología, Fac. de Ciencias-UNAM (1986)
-
Doctorado
-
Biol. Bolivar Jesus Arcos Encarnacion
Análisis de la proteína KChIP3 en el desarrollo de la Enfermedad de Alzheimer. -
M.C. Maria del Sol Díaz de León Guerrero
Efecto de un paradigma de ambiente enriquecido en un modelo murino de obesidad y diabetes tipo II -
M.C. Roberto Carlos Licea Cejudo
Estudio de la funcion de KChIP3 en el desarrollo de cancer de tiroides -
Impacto de un paradigma de ambiente enriquecido sobre el metiloma hipotalámico en respuesta a la disbiosis resultante de una dieta alta en grasa
-
En busca de las moléculas inmunomoduladoras de los estados de activación de la microglía: una alternativa para la enfermedad de Alzheimer.
-
M.C. Cristina Elizabeth Ramírez Serrano
Evaluación farmacológica de una mezcla de compuestos activos presentes en M. parviflora en un modelo murino de la Enfermedad de Alzheimer
-
Maestría
-
Carlos Humberto Martinez Alvarez
Papel de TRPV1 com o regulador de la inflamación y homeostasis de calcio en la enfermedad de Alzheimer.
-
Licenciatura
-
Estancia Temporal
Total de publicaciones: 59
- Tipo
- Fecha
Artículo
1 - Arango-De la Pava, L. D., Zamilpa, A., Trejo-Espino, J. L., Dominguez-Mendoza, B. E., Jimenez-Ferrer, E., Perez-Martinez, L., Trejo-Tapia, G. (2021). Synergism and Subadditivity of Verbascoside-Lignans and -Iridoids Binary Mixtures Isolated from Castilleja tenuiflora Benth. on NF- k B/AP-1 Inhibition Activity.
Molecules,
26 (3),
547.
Artículo
2 - Licea-Cejudo,R.C., Arenas-Sandoval,L.K., Salazar-Leon,J., Martinez-Martinez,M.V., Carreon-Rodriguez,A., Pedraza-Alva,G., Perez-Martinez,L. (2020). A dysfunctional family environment and a high body fat percentage negatively affect telomere length in Mexican boys aged 8-10 years.
Acta Paediatrica,
109 (10),
2091-2098.
Artículo
3 - Sanchez,N.C., Medrano-Jimenez,E., Aguilar-Leon,D., Perez-Martinez,L., Pedraza-Alva,G. (2020). Tumor Necrosis Factor-Induced miR-146a Upregulation Promotes Human Lung Adenocarcinoma Metastasis by Targeting Merlin.
DNA and Cell Biology,
39 (3),
484-497.
Artículo
4 - Medrano-Jimenez, E., Jimenez-Ferrer Carrillo, I., Pedraza-Escalona, M., Ramirez-Serrano, C. E., Alvarez-Arellano, L., Cortes-Mendoza, J., Herrera-Ruiz, M., Jimenez-Ferrer, E., Zamilpa, A., Tortoriello, J., Pedraza-Alva, G., Perez-Martinez, L. (2019). Malva parviflora extract ameliorates the deleterious effects of a high fat diet on the cognitive deficit in a mouse model of Alzheimer's disease by restoring microglial function via a PPAR-gamma-dependent mechanism.
Journal of Neuroinflammation,
16 (1),
143.
Artículo
5 - Ramirez-Carreto,S., Perez-Garcia,E.I., Salazar-Garcia,S.I., Bernaldez-Sarabia,J., Licea-Navarro,A., Rudino-Pinera,E., Perez-Martinez,L., Pedraza-Alva,G., Rodriguez-Almazan,C. (2019). Identification of a pore-forming protein from sea anemone Anthopleura dowii Verrill (1869) venom by mass spectrometry.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
25,
e144118.
Artículo
6 - Ramirez-Serrano,C.E., Jimenez-Ferrer,E., Herrera-Ruiz,M., Zamilpa,A., Vargas-Villa,G., Ramirez-Carreto,R.J., Chavarria,A., Tortoriello,J., Pedraza-Alva,G., Perez-Martinez,L. (2019). A Malva parviflora's fraction prevents the deleterious effects resulting from neuroinflammation.
Biomedicine and Pharmacotherapy,
118,
109349-109349.
Artículo
7 - Salazar-Leon,J., Valdez-Hernandez,A.L., Garcia-Jimenez,S., Roman-Dominguez,L., Huanosta-Murillo,E., Bonifaz,L.C., Perez-Martinez,L., Pedraza-Alva,G. (2019). Nlrp1b1 negatively modulates obesity-induced inflammation by promoting IL-18 production.
Scientific Reports,
9 (1),
13815.
Artículo
8 - Villanueva-Flores,F., Miranda-Hernandez,M., Flores-Flores,J.O., Porras-Sanjuanico,A., Hu,H., Perez-Martinez,L., Ramirez,O.T., Palomares,L.A. (2019). Poly(vinyl alcohol co-vinyl acetate) as a novel scaffold for mammalian cell culture and controlled drug release.
Journal of Materials Science,
54 (10),
7867-7882.
Artículo
9 - Villasenor,T., Madrid-Paulino,E., Maldonado-Bravo,R., Perez-Martinez,L., Pedraza-Alva,G. (2019). Mycobacterium bovis BCG promotes IL-10 expression by establishing a SYK/PKCalpha/beta positive autoregulatory loop that sustains STAT3 activation.
Pathogens and Disease,
77 (3),
ftz032.
Artículo
10 - Alvarez-Arellano, L., Pedraza-Escalona, M., Blanco-Ayala, T., Camacho-Concha, N., Cortes-Mendoza, J., Perez-Martinez, L., Pedraza-Alva, G. (2018). Autophagy impairment by caspase-1-dependent inflammation mediates memory loss in response to beta-Amyloid peptide accumulation.
Journal of Neuroscience Research,
96 (2),
234-246.
Artículo
11 - Villasenor, T., Madrid-Paulino, E., Maldonado-Bravo, R., Urban-Aragon, A., Perez-Martinez, L., Pedraza-Alva, G. (2017). Activation of the Wnt Pathway by Mycobacterium tuberculosis: A Wnt-Wnt Situation.
Frontiers in Immunology,
8,
50.
Artículo
12 - Martinez-Armenta,M., de Leon-Guerrero,S.D., Catalan,A., Alvarez-Arellano,L., Uribe,R.M., Subramaniam,M., Charli,J.L., Perez-Martinez,L. (2015). TGFbeta2 regulates hypothalamic Trh expression through the TGFbeta inducible early gene-1 (TIEG1) during fetal development.
Molecular and Cellular Endocrinology,
400,
129-139.
Artículo
13 - Miquelajauregui,A., Sandoval-Schaefer,T., Martinez-Armenta,M., Perez-Martinez,L., Carabez,A., Zhao,Y., Heide,M., Alvarez-Bolado,G., Varela-Echavarria,A. (2015). LIM homeobox protein 5 (Lhx5) is essential for mamillary body development.
Frontiers in Neuroanatomy,
9,
136.
Revisión
14 - Pedraza-Alva,G., Perez-Martinez,L., Valdez-Hernandez,L., Meza-Sosa,K.F., Ando-Kuri,M. (2015). Negative regulation of the inflammasome: keeping inflammation under control.
Immunological Reviews,
265 (1),
231-257.
Artículo
15 - Perez-Garcia,E.I., Meza-Sosa,K.F., Lopez-Sevilla,Y., Camacho-Concha,N., Sanchez,N.C., Perez-Martinez,L., Pedraza-Alva,G. (2015). Merlin negative regulation by miR-146a promotes cell transformation.
Biochemical and Biophysical Research Communications,
468 (4),
594-600.
Revisión
16 - Meza-Sosa,K.F., Pedraza-Alva,G., Perez-Martinez,L. (2014). microRNAs: key triggers of neuronal cell fate.
Frontiers in Cellular Neuroscience,
8,
175.
Artículo
17 - Meza-Sosa,K.F., Perez-Garcia,E.I., Camacho-Concha,N., Lopez-Gutierrez,O., Pedraza-Alva,G., Perez-Martinez,L. (2014). MiR-7 Promotes Epithelial Cell Transformation by Targeting the Tumor Suppressor KLF4.
PLoS ONE,
9 (9),
e103987.
Artículo
18 - Carreon-Rodriguez,A., Perez-Martinez,L. (2013). El papel de los receptores de hormonas tiroideas en el desarrollo del sistema nervioso .
eNeurobiologia,
4 (7),
240513.
Artículo
19 - Cortes-Mendoza,J., Leon-Guerrero,S.D., Pedraza-Alva,G., Perez-Martinez,L. (2013). Shaping synaptic plasticity: the role of activity-mediated epigenetic regulation on gene transcription.
International Journal of Developmental Neuroscience,
31 (6),
359-369.
Artículo
20 - Meza-Sosa,K.F., Valle-Garcia,D., Pedraza-Alva,G., Perez-Martinez,L. (2013). MicroARNs, los pequeños grandes actores del sistema nervioso.
Ciencia, Revista de la Academia Mexicana de Ciencia,
64 (1),
79-86.
Revisión
21 - Carreon-Rodriguez,A., Perez-Martinez,L. (2012). Clinical implications of thyroid hormones effects on nervous system development.
Pediatric endocrinology reviews,
9 (3),
644-649 [erratum en 9 (4) 744].
Revisión
22 - Meza-Sosa,K.F., Valle-Garcia,D., Pedraza-Alva,G., Perez-Martinez,L. (2012). Role of microRNAs in central nervous system development and pathology.
Journal of Neuroscience Research,
90 (1),
1-12.
Revisión
23 - Diaz de Leon-Guerrero,S., Pedraza-Alva,G., Perez-Martinez,L. (2011). In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system.
European Journal of Neuroscience,
33 (9),
1563-1574.
Artículo
24 - Guerra-Crespo,M., Perez-Monter,C., Janga,S.C., Castillo-Ramirez,S., Gutierrez-Rios,R.M., Joseph-Bravo,P., Perez-Martinez,L., Charli,J.L. (2011). Transcriptional profiling of fetal hypothalamic TRH neurons.
BMC Genomics,
12 (1),
222.
Artículo
25 - Perez-Monter,C., Martinez-Armenta,M., Miquelajauregui,A., Furlan-Magaril,M., Varela-Echavarria,A., Recillas-Targa,F., May,V., Charli,J.L., Perez-Martinez,L. (2011). The Kruppel-like factor 4 controls biosynthesis of thyrotropin-releasing hormone during hypothalamus development.
Molecular and Cellular Endocrinology,
333 (2),
127-133.
Artículo
26 - Carreon-Rodriguez,A., Charli,J.L., Perez-Martinez,L. (2009). T3 differentially regulates TRH expression in developing hypothalamic neurons in vitro.
Brain Research,
1305,
20-30.
Artículo
27 - Pedraza-Alva,G., Zingg,J.M., Donda,A., Perez-Martinez,L. (2009). Estrogen receptor regulates MyoD gene expression by preventing AP-1-mediated repression.
Biochemical and Biophysical Research Communications,
389 (2),
360-365.
Artículo
28 - Cote-Velez,A., Perez-Martinez,L., Charli,J.L., Joseph-Bravo,P. (2008). The PKC and ERK/MAPK Pathways Regulate Glucocorticoid Action on TRH Transcription.
Neurochemical Research,
33 (8),
1582-1591.
Artículo
29 - Ubieta,R., Uribe,R.M., Gonzalez,J.A., Garcia-Vazquez,A., Perez-Monter,C., Perez-Martinez,L., Joseph-Bravo,P., Charli,J.L. (2007). BDNF up-regulates pre-pro-TRH mRNA expression in the fetal/neonatal paraventricular nucleus of the hypothalamus. Properties of the transduction pathway.
Brain Research,
1174,
28-38.
Artículo
30 - Jaworski,D.M., Perez-Martinez,L. (2006). Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) expression is regulated by multiple neural differentiation signals.
Journal of Neurochemistry,
98 (1),
234-247.
*
Artículo
31 - Cote-Velez,A., Perez-Martinez,L., Diaz-Gallardo,M.Y., Perez-Monter,C., Carreon,A., Charli,J.L., Joseph-Bravo,P. (2005). Dexamethasone repressed cAMP rapid upregulation of TRH gene transcription. Identification of a composite GRE and a CRE in TRH promoter.
Journal of Molecular Endocrinology,
34 (1),
177-197.
Artículo
32 - Perez-Martinez,L., Jaworski,D.M. (2005). Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal.
Journal of Neuroscience,
25 (20),
4917-4929.
Artículo
33 - Guerra-Crespo,M., Charli,J.L., Rosales-Garcia,VH, Pedraza-Alva,G., Perez-Martinez,L. (2003). Polyethylenimine improves the transfection efficiency of primary cultures of post-mitotic rat fetal hypothalamic neurons.
Journal of Neuroscience Methods,
127 (2),
179-192.
Artículo
34 - Joseph-Bravo,P., Perez-Martinez,L., Lezama,L., Morales-Chapa,C., Charli,J.L. (2002). An improved method for the expression of TRH in serum-supplemented primary cultures of fetal hypothalamic cells.
Brain Research Protocols,
9 (2),
93-104.
Artículo
35 - Guerra-Crespo,M., Ubieta,R., Joseph-Bravo,P., Charli,J.L., Perez-Martinez,L. (2001). BDNF increases the early expression of TRH mRNA in fetal TrkB+ hypothalamic neurons in primary culture.
European Journal of Neuroscience,
14 (3),
483-494.
Artículo
36 - Perez-Martinez,L., Charli,J., Joseph-Bravo,P. (2001). Development of pro-TRH gene expression in primary cultures of fetal hypothalamic cells.
Developmental Brain Research,
130 (1),
73-81.
Revisión
37 - de Gortari,P., Mendez,M., Rodriguez-Keller,I., Perez-Martinez,L., Joseph-Bravob,P. (2000). Acute ethanol administration induces changes in TRH and proenkephalin expression in hypothalamic and limbic regions of rat brain.
Neurochemistry International,
37 (5-6),
483-496.
Artículo
38 - Niquet,J., Perez-Martinez,L., Guerra,M., Grouselle,D., Joseph-Bravo,P., Charli,J. (2000). Extracellular matrix proteins increase the expression of pro-TRH and pro-protein convertase PC1 in fetal hypothalamic neurons in vitro.
Developmental Brain Research,
120 (1),
49-56.
Artículo
39 - Perez-Martinez,L., Uribe,R.M., Sanchez,E., Carreon-Rodriguez,A., Chavez,L., Zacarias,M., Joseph-Bravo,P., Charli,J.L. (1999). Regulation of TRH biosynthesis in the paraventricular nucleus of rodent hypothalamus.
Current topics in neurochemistry,
2,
79-88.
Artículo; Actas Paper
40 - Charli,J.L., Vargas,M.A., Cisneros,M., de Gortari,P., Baeza,M.A., Jasso,P., Bourdais,J., Perez,L., Uribe,R.M., Joseph-Bravo,P. (1998). TRH inactivation in the extracellular compartment: role of pyroglutamyl peptidase II.
Neurobiology (Bp.),
6 (1),
45-57.
Revisión
41 - Joseph-Bravo,P., Uribe,R.M., Vargas,M.A., Perez-Martinez,L., Zoeller,T., Charli,J.L. (1998). Multifactorial modulation of TRH metabolism.
Cellular & Molecular Neurobiology,
18 (2),
231-247.
Artículo
42 - Perez-Martinez,L., Carreon-Rodriguez,A., Gonzalez-Alzati,M.E., Morales,C., Charli,J.L., Joseph-Bravo,P. (1998). Dexamethasone rapidly regulates TRH mRNA levels in hypothalamic cell cultures: interaction with the cAMP pathway.
Neuroendocrinology,
68 (5),
345-354.
Artículo
43 - Perez,L., Urich,M., Paasinen,A., Senften,M., Meili,R., Ballmerhofer,K. (1995). Domains in Middle-T Antigen That Cooperate in Polyomavirus-Mediated Oncogenic Transformation.
Virology,
208 (1),
26-37.
*
Artículo
44 - Uribe,R.M., Perez-Martinez,L., Covarrubias,M.D., Gomez,O., Covarrubias,L., Charli,J.L., Joseph-Bravo,P. (1995). Phorbol ester or cAMP enhance thyrotropin-releasing hormone mRNA in primary cultures of hypothalamic cells.
Neuroscience Letters,
201 (1),
41-44.
Artículo
45 - Perez,L., Paasinen,A., Schnierle,B., Kach,S., Senften,M., Ballmerhofer,K. (1993). Mitosis-Specific Phosphorylation of Polyomavirus Middle-Sized Tumor-Antigen and Its Role During Cell-Transformation.
Proceedings of the National Academy of Sciences of the United States of America,
90 (17),
8113-8117.
*
Artículo
46 - Jaffe,C.L., Perez,L.M., Schnur,L.F. (1990). Lipophosphoglycan and Secreted Acid-Phosphatase of Leishmania-Tropica Share Species-Specific Epitopes.
Molecular and Biochemical Parasitology,
41 (2),
233-240.
*
Artículo
47 - Jaffe,C.L., Perez,M.L., Sarfstein,R. (1990). Leishmania-Tropica - Characterization of A Lipophosphoglycan-Like Antigen Recognized by Species-Specific Monoclonal-Antibodies.
Experimental Parasitology,
70 (1),
12-24.
*
Internacional
48 - Alvarez-Arellano,L., Diaz de Leon-Guerrero,S., Meza-Sosa,K.F., Jimenez-Ferrer C.,I., Perez-Martinez,L. (2013). Neurodegenerative disorders and inflammation. Molecular aspects of inflammation.
173-207,
Kerala: Research Signpost.
Internacional
49 - Carreon-Rodriguez,A., Perez-Martinez,L. (2012). Role of Thyroid Hormones on Hypothalamus Development and Function. Advances in Medicine and Biology vol 49.
1-20,
New York.
Internacional
50 - Perez-Martinez,L., Pedraza-Alva,G. (2012). Cell signaling: From non-specific bands to posttranslational modifications-mediated protein-protein interactions. Tools to Understand Protein-Protein Interactions.
21-40,
Kerala: Research Signpost.
Internacional
51 - Joseph-Bravo,P., Cote-Velez,A., Perez-Martinez,L. (2006). Integration of Neuroendocrine Signals that Regulate the Activity of Hypophysiotropic Peptides. Molecular Endocrinology.
1-24,
Kerala, India: Research Signpost.
Internacional
52 - Perez-Martinez,L., Charli,J.L. (2006). Factors Involved in the Establishment of Hypothalamic Neuroendocrine Phenotypes. Molecular Endocrinology.
127-147,
Kerala, India: Research Signpost.
Internacional
53 - Perez-Martinez,L., Pedraza-Alva,G., Ferat-Osorio,E. (2013). Molecular aspects of inflammation.
1-231,
Kerala: Research Signpost.
Editorial material
54 - Pedraza-Alva,G., Ramirez-Serrano,C.E., Pedraza,F., Flores-Vallejo,R.C., Villarreal,M.L., Perez-Martinez,L. (2019). From traditional remedies to cutting-edge medicine: using ancient Mesoamerican knowledge to address complex disorders relevant to psychoneuroimmunology.
Brain, Behavior, and Immunity,
79,
3-5.
Divulgación
55 - Licea-Cejudo, R.C., Pedraza-Alva, G., Perez-Martinez, L. (2018). Obesidad infantil: Crónica de una vejez anunciada.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
12,
17-19.
Divulgación
56 - Perez-Martinez,L., Martinez-Armenta,M., Cortes-Mendoza,J. (2015). Del ADN a la neurona: un vistazo a la expresión génica del cerebro.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
3,
5-8.
Nacional
57 - Carreon-Rodriguez,A., Perez-Martinez,L., Joseph-Bravo,P. (2008). La participación de las hormonas tiroideas en el desarrollo y función del sistema nervioso.
Facultad de Medicina. Revista Actualidades de Posgrado para el Médico General,
12 (5),
9-12.
Nacional
58 - Guerra-Crespo,M., Charli,J.L., Perez-Martinez,L. (2005). Los arreglos de DNA: explorando la expresion genetica del cerebro.
Ciencia, Revista de la Academia Mexicana de Ciencia,
56,
67-76.
59 - Perez Martinez, Leonor (1986). Efecto Mitogenico de un oligonucleotido de ARN de la larva de Taenia solium sobre linfocitos estimulados con fitohemaglutinina.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
Artículo
60 - Arango-De la Pava, L. D., Zamilpa, A., Trejo-Espino, J. L., Dominguez-Mendoza, B. E., Jimenez-Ferrer, E., Perez-Martinez, L., Trejo-Tapia, G.. Synergism and Subadditivity of Verbascoside-Lignans and -Iridoids Binary Mixtures Isolated from Castilleja tenuiflora Benth. on NF- k B/AP-1 Inhibition Activity.
Molecules,
26 (3),
547.
Artículo
61 - Licea-Cejudo,R.C., Arenas-Sandoval,L.K., Salazar-Leon,J., Martinez-Martinez,M.V., Carreon-Rodriguez,A., Pedraza-Alva,G., Perez-Martinez,L.. A dysfunctional family environment and a high body fat percentage negatively affect telomere length in Mexican boys aged 8-10 years.
Acta Paediatrica,
109 (10),
2091-2098.
Artículo
62 - Sanchez,N.C., Medrano-Jimenez,E., Aguilar-Leon,D., Perez-Martinez,L., Pedraza-Alva,G.. Tumor Necrosis Factor-Induced miR-146a Upregulation Promotes Human Lung Adenocarcinoma Metastasis by Targeting Merlin.
DNA and Cell Biology,
39 (3),
484-497.
Artículo
63 - Medrano-Jimenez, E., Jimenez-Ferrer Carrillo, I., Pedraza-Escalona, M., Ramirez-Serrano, C. E., Alvarez-Arellano, L., Cortes-Mendoza, J., Herrera-Ruiz, M., Jimenez-Ferrer, E., Zamilpa, A., Tortoriello, J., Pedraza-Alva, G., Perez-Martinez, L.. Malva parviflora extract ameliorates the deleterious effects of a high fat diet on the cognitive deficit in a mouse model of Alzheimer's disease by restoring microglial function via a PPAR-gamma-dependent mechanism.
Journal of Neuroinflammation,
16 (1),
143.
Artículo
64 - Ramirez-Carreto,S., Perez-Garcia,E.I., Salazar-Garcia,S.I., Bernaldez-Sarabia,J., Licea-Navarro,A., Rudino-Pinera,E., Perez-Martinez,L., Pedraza-Alva,G., Rodriguez-Almazan,C.. Identification of a pore-forming protein from sea anemone Anthopleura dowii Verrill (1869) venom by mass spectrometry.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
25,
e144118.
Artículo
65 - Ramirez-Serrano,C.E., Jimenez-Ferrer,E., Herrera-Ruiz,M., Zamilpa,A., Vargas-Villa,G., Ramirez-Carreto,R.J., Chavarria,A., Tortoriello,J., Pedraza-Alva,G., Perez-Martinez,L.. A Malva parviflora's fraction prevents the deleterious effects resulting from neuroinflammation.
Biomedicine and Pharmacotherapy,
118,
109349-109349.
Artículo
66 - Salazar-Leon,J., Valdez-Hernandez,A.L., Garcia-Jimenez,S., Roman-Dominguez,L., Huanosta-Murillo,E., Bonifaz,L.C., Perez-Martinez,L., Pedraza-Alva,G.. Nlrp1b1 negatively modulates obesity-induced inflammation by promoting IL-18 production.
Scientific Reports,
9 (1),
13815.
Artículo
67 - Villanueva-Flores,F., Miranda-Hernandez,M., Flores-Flores,J.O., Porras-Sanjuanico,A., Hu,H., Perez-Martinez,L., Ramirez,O.T., Palomares,L.A.. Poly(vinyl alcohol co-vinyl acetate) as a novel scaffold for mammalian cell culture and controlled drug release.
Journal of Materials Science,
54 (10),
7867-7882.
Artículo
68 - Villasenor,T., Madrid-Paulino,E., Maldonado-Bravo,R., Perez-Martinez,L., Pedraza-Alva,G.. Mycobacterium bovis BCG promotes IL-10 expression by establishing a SYK/PKCalpha/beta positive autoregulatory loop that sustains STAT3 activation.
Pathogens and Disease,
77 (3),
ftz032.
Editorial material
69 - Pedraza-Alva,G., Ramirez-Serrano,C.E., Pedraza,F., Flores-Vallejo,R.C., Villarreal,M.L., Perez-Martinez,L.. From traditional remedies to cutting-edge medicine: using ancient Mesoamerican knowledge to address complex disorders relevant to psychoneuroimmunology.
Brain, Behavior, and Immunity,
79,
3-5.
Artículo
70 - Alvarez-Arellano, L., Pedraza-Escalona, M., Blanco-Ayala, T., Camacho-Concha, N., Cortes-Mendoza, J., Perez-Martinez, L., Pedraza-Alva, G.. Autophagy impairment by caspase-1-dependent inflammation mediates memory loss in response to beta-Amyloid peptide accumulation.
Journal of Neuroscience Research,
96 (2),
234-246.
Divulgación
71 - Licea-Cejudo, R.C., Pedraza-Alva, G., Perez-Martinez, L.. Obesidad infantil: Crónica de una vejez anunciada.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
12,
17-19.
Artículo
72 - Villasenor, T., Madrid-Paulino, E., Maldonado-Bravo, R., Urban-Aragon, A., Perez-Martinez, L., Pedraza-Alva, G.. Activation of the Wnt Pathway by Mycobacterium tuberculosis: A Wnt-Wnt Situation.
Frontiers in Immunology,
8,
50.
Artículo
73 - Martinez-Armenta,M., de Leon-Guerrero,S.D., Catalan,A., Alvarez-Arellano,L., Uribe,R.M., Subramaniam,M., Charli,J.L., Perez-Martinez,L.. TGFbeta2 regulates hypothalamic Trh expression through the TGFbeta inducible early gene-1 (TIEG1) during fetal development.
Molecular and Cellular Endocrinology,
400,
129-139.
Artículo
74 - Miquelajauregui,A., Sandoval-Schaefer,T., Martinez-Armenta,M., Perez-Martinez,L., Carabez,A., Zhao,Y., Heide,M., Alvarez-Bolado,G., Varela-Echavarria,A.. LIM homeobox protein 5 (Lhx5) is essential for mamillary body development.
Frontiers in Neuroanatomy,
9,
136.
Revisión
75 - Pedraza-Alva,G., Perez-Martinez,L., Valdez-Hernandez,L., Meza-Sosa,K.F., Ando-Kuri,M.. Negative regulation of the inflammasome: keeping inflammation under control.
Immunological Reviews,
265 (1),
231-257.
Artículo
76 - Perez-Garcia,E.I., Meza-Sosa,K.F., Lopez-Sevilla,Y., Camacho-Concha,N., Sanchez,N.C., Perez-Martinez,L., Pedraza-Alva,G.. Merlin negative regulation by miR-146a promotes cell transformation.
Biochemical and Biophysical Research Communications,
468 (4),
594-600.
Divulgación
77 - Perez-Martinez,L., Martinez-Armenta,M., Cortes-Mendoza,J.. Del ADN a la neurona: un vistazo a la expresión génica del cerebro.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
3,
5-8.
Revisión
78 - Meza-Sosa,K.F., Pedraza-Alva,G., Perez-Martinez,L.. microRNAs: key triggers of neuronal cell fate.
Frontiers in Cellular Neuroscience,
8,
175.
Artículo
Artículo
80 - Carreon-Rodriguez,A., Perez-Martinez,L.. El papel de los receptores de hormonas tiroideas en el desarrollo del sistema nervioso .
eNeurobiologia,
4 (7),
240513.
Artículo
81 - Cortes-Mendoza,J., Leon-Guerrero,S.D., Pedraza-Alva,G., Perez-Martinez,L.. Shaping synaptic plasticity: the role of activity-mediated epigenetic regulation on gene transcription.
International Journal of Developmental Neuroscience,
31 (6),
359-369.
Artículo
82 - Meza-Sosa,K.F., Valle-Garcia,D., Pedraza-Alva,G., Perez-Martinez,L.. MicroARNs, los pequeños grandes actores del sistema nervioso.
Ciencia, Revista de la Academia Mexicana de Ciencia,
64 (1),
79-86.
Internacional
83 - Alvarez-Arellano,L., Diaz de Leon-Guerrero,S., Meza-Sosa,K.F., Jimenez-Ferrer C.,I., Perez-Martinez,L.. Neurodegenerative disorders and inflammation. Molecular aspects of inflammation.
173-207,
Kerala: Research Signpost.
Internacional
84 - Perez-Martinez,L., Pedraza-Alva,G., Ferat-Osorio,E.. Molecular aspects of inflammation.
1-231,
Kerala: Research Signpost.
Revisión
85 - Carreon-Rodriguez,A., Perez-Martinez,L.. Clinical implications of thyroid hormones effects on nervous system development.
Pediatric endocrinology reviews,
9 (3),
644-649 [erratum en 9 (4) 744].
Revisión
86 - Meza-Sosa,K.F., Valle-Garcia,D., Pedraza-Alva,G., Perez-Martinez,L.. Role of microRNAs in central nervous system development and pathology.
Journal of Neuroscience Research,
90 (1),
1-12.
Internacional
87 - Carreon-Rodriguez,A., Perez-Martinez,L.. Role of Thyroid Hormones on Hypothalamus Development and Function. Advances in Medicine and Biology vol 49.
1-20,
New York.
Internacional
88 - Perez-Martinez,L., Pedraza-Alva,G.. Cell signaling: From non-specific bands to posttranslational modifications-mediated protein-protein interactions. Tools to Understand Protein-Protein Interactions.
21-40,
Kerala: Research Signpost.
Revisión
89 - Diaz de Leon-Guerrero,S., Pedraza-Alva,G., Perez-Martinez,L.. In sickness and in health: the role of methyl-CpG binding protein 2 in the central nervous system.
European Journal of Neuroscience,
33 (9),
1563-1574.
Artículo
90 - Guerra-Crespo,M., Perez-Monter,C., Janga,S.C., Castillo-Ramirez,S., Gutierrez-Rios,R.M., Joseph-Bravo,P., Perez-Martinez,L., Charli,J.L.. Transcriptional profiling of fetal hypothalamic TRH neurons.
BMC Genomics,
12 (1),
222.
Artículo
91 - Perez-Monter,C., Martinez-Armenta,M., Miquelajauregui,A., Furlan-Magaril,M., Varela-Echavarria,A., Recillas-Targa,F., May,V., Charli,J.L., Perez-Martinez,L.. The Kruppel-like factor 4 controls biosynthesis of thyrotropin-releasing hormone during hypothalamus development.
Molecular and Cellular Endocrinology,
333 (2),
127-133.
Artículo
92 - Carreon-Rodriguez,A., Charli,J.L., Perez-Martinez,L.. T3 differentially regulates TRH expression in developing hypothalamic neurons in vitro.
Brain Research,
1305,
20-30.
Artículo
93 - Pedraza-Alva,G., Zingg,J.M., Donda,A., Perez-Martinez,L.. Estrogen receptor regulates MyoD gene expression by preventing AP-1-mediated repression.
Biochemical and Biophysical Research Communications,
389 (2),
360-365.
Artículo
94 - Cote-Velez,A., Perez-Martinez,L., Charli,J.L., Joseph-Bravo,P.. The PKC and ERK/MAPK Pathways Regulate Glucocorticoid Action on TRH Transcription.
Neurochemical Research,
33 (8),
1582-1591.
Nacional
95 - Carreon-Rodriguez,A., Perez-Martinez,L., Joseph-Bravo,P.. La participación de las hormonas tiroideas en el desarrollo y función del sistema nervioso.
Facultad de Medicina. Revista Actualidades de Posgrado para el Médico General,
12 (5),
9-12.
Artículo
96 - Ubieta,R., Uribe,R.M., Gonzalez,J.A., Garcia-Vazquez,A., Perez-Monter,C., Perez-Martinez,L., Joseph-Bravo,P., Charli,J.L.. BDNF up-regulates pre-pro-TRH mRNA expression in the fetal/neonatal paraventricular nucleus of the hypothalamus. Properties of the transduction pathway.
Brain Research,
1174,
28-38.
Artículo
97 - Jaworski,D.M., Perez-Martinez,L.. Tissue Inhibitor of Metalloproteinase-2 (TIMP-2) expression is regulated by multiple neural differentiation signals.
Journal of Neurochemistry,
98 (1),
234-247.
*
Internacional
98 - Joseph-Bravo,P., Cote-Velez,A., Perez-Martinez,L.. Integration of Neuroendocrine Signals that Regulate the Activity of Hypophysiotropic Peptides. Molecular Endocrinology.
1-24,
Kerala, India: Research Signpost.
Internacional
99 - Perez-Martinez,L., Charli,J.L.. Factors Involved in the Establishment of Hypothalamic Neuroendocrine Phenotypes. Molecular Endocrinology.
127-147,
Kerala, India: Research Signpost.
Artículo
100 - Cote-Velez,A., Perez-Martinez,L., Diaz-Gallardo,M.Y., Perez-Monter,C., Carreon,A., Charli,J.L., Joseph-Bravo,P.. Dexamethasone repressed cAMP rapid upregulation of TRH gene transcription. Identification of a composite GRE and a CRE in TRH promoter.
Journal of Molecular Endocrinology,
34 (1),
177-197.
Artículo
101 - Perez-Martinez,L., Jaworski,D.M.. Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal.
Journal of Neuroscience,
25 (20),
4917-4929.
Nacional
102 - Guerra-Crespo,M., Charli,J.L., Perez-Martinez,L.. Los arreglos de DNA: explorando la expresion genetica del cerebro.
Ciencia, Revista de la Academia Mexicana de Ciencia,
56,
67-76.
Artículo
103 - Guerra-Crespo,M., Charli,J.L., Rosales-Garcia,VH, Pedraza-Alva,G., Perez-Martinez,L.. Polyethylenimine improves the transfection efficiency of primary cultures of post-mitotic rat fetal hypothalamic neurons.
Journal of Neuroscience Methods,
127 (2),
179-192.
Artículo
104 - Joseph-Bravo,P., Perez-Martinez,L., Lezama,L., Morales-Chapa,C., Charli,J.L.. An improved method for the expression of TRH in serum-supplemented primary cultures of fetal hypothalamic cells.
Brain Research Protocols,
9 (2),
93-104.
Artículo
105 - Guerra-Crespo,M., Ubieta,R., Joseph-Bravo,P., Charli,J.L., Perez-Martinez,L.. BDNF increases the early expression of TRH mRNA in fetal TrkB+ hypothalamic neurons in primary culture.
European Journal of Neuroscience,
14 (3),
483-494.
Artículo
106 - Perez-Martinez,L., Charli,J., Joseph-Bravo,P.. Development of pro-TRH gene expression in primary cultures of fetal hypothalamic cells.
Developmental Brain Research,
130 (1),
73-81.
Revisión
107 - de Gortari,P., Mendez,M., Rodriguez-Keller,I., Perez-Martinez,L., Joseph-Bravob,P.. Acute ethanol administration induces changes in TRH and proenkephalin expression in hypothalamic and limbic regions of rat brain.
Neurochemistry International,
37 (5-6),
483-496.
Artículo
108 - Niquet,J., Perez-Martinez,L., Guerra,M., Grouselle,D., Joseph-Bravo,P., Charli,J.. Extracellular matrix proteins increase the expression of pro-TRH and pro-protein convertase PC1 in fetal hypothalamic neurons in vitro.
Developmental Brain Research,
120 (1),
49-56.
Artículo
109 - Perez-Martinez,L., Uribe,R.M., Sanchez,E., Carreon-Rodriguez,A., Chavez,L., Zacarias,M., Joseph-Bravo,P., Charli,J.L.. Regulation of TRH biosynthesis in the paraventricular nucleus of rodent hypothalamus.
Current topics in neurochemistry,
2,
79-88.
Artículo; Actas Paper
110 - Charli,J.L., Vargas,M.A., Cisneros,M., de Gortari,P., Baeza,M.A., Jasso,P., Bourdais,J., Perez,L., Uribe,R.M., Joseph-Bravo,P.. TRH inactivation in the extracellular compartment: role of pyroglutamyl peptidase II.
Neurobiology (Bp.),
6 (1),
45-57.
Revisión
111 - Joseph-Bravo,P., Uribe,R.M., Vargas,M.A., Perez-Martinez,L., Zoeller,T., Charli,J.L.. Multifactorial modulation of TRH metabolism.
Cellular & Molecular Neurobiology,
18 (2),
231-247.
Artículo
112 - Perez-Martinez,L., Carreon-Rodriguez,A., Gonzalez-Alzati,M.E., Morales,C., Charli,J.L., Joseph-Bravo,P.. Dexamethasone rapidly regulates TRH mRNA levels in hypothalamic cell cultures: interaction with the cAMP pathway.
Neuroendocrinology,
68 (5),
345-354.
Artículo
113 - Perez,L., Urich,M., Paasinen,A., Senften,M., Meili,R., Ballmerhofer,K.. Domains in Middle-T Antigen That Cooperate in Polyomavirus-Mediated Oncogenic Transformation.
Virology,
208 (1),
26-37.
*
Artículo
114 - Uribe,R.M., Perez-Martinez,L., Covarrubias,M.D., Gomez,O., Covarrubias,L., Charli,J.L., Joseph-Bravo,P.. Phorbol ester or cAMP enhance thyrotropin-releasing hormone mRNA in primary cultures of hypothalamic cells.
Neuroscience Letters,
201 (1),
41-44.
Artículo
115 - Perez,L., Paasinen,A., Schnierle,B., Kach,S., Senften,M., Ballmerhofer,K.. Mitosis-Specific Phosphorylation of Polyomavirus Middle-Sized Tumor-Antigen and Its Role During Cell-Transformation.
Proceedings of the National Academy of Sciences of the United States of America,
90 (17),
8113-8117.
*
Artículo
116 - Jaffe,C.L., Perez,L.M., Schnur,L.F.. Lipophosphoglycan and Secreted Acid-Phosphatase of Leishmania-Tropica Share Species-Specific Epitopes.
Molecular and Biochemical Parasitology,
41 (2),
233-240.
*
Artículo
117 - Jaffe,C.L., Perez,M.L., Sarfstein,R.. Leishmania-Tropica - Characterization of A Lipophosphoglycan-Like Antigen Recognized by Species-Specific Monoclonal-Antibodies.
Experimental Parasitology,
70 (1),
12-24.
*
118 - Perez Martinez, Leonor. Efecto Mitogenico de un oligonucleotido de ARN de la larva de Taenia solium sobre linfocitos estimulados con fitohemaglutinina.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.