Dr. Miguel Angel Vargas Suarez
Investigador
Número de registros: 2
- Vencidos
- Papel fisiológico de la piroglutamil peptidasa ii en la comunicación thrérgica., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2006 - 2009
- Localización subcelular y tráfico de la piroglutamil aminopeptidasa ii., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2003 - 2005
Nivel b del Pride
Nivel I del SNI
Nivel I del SNI
Doctorado, en Investigacion Biomedica Basica, CEINGEBI-UNAM (1991)
Maestría, en Investigacion Biomedica Basica, CEINGEBI-UNAM (1988)
Licenciatura, Biología, ENEP-Iztacala-UNAM (1984)
1 - Lazcano Sanchez, Ivan (2007). Efecto de la inhibicion de la Piroglutamil peptidasa II sobre la secrecion de prolactina y tirotropina en la adenohipofisis.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
Asesor: Vargas Suarez, Miguel Angel
2 - Herrera Diaz, Jorge (1990). Ontogenia de la actividad de la piroglutamato aminopeptidasa II en varias zonas del cerebro y pancreas de la rata .
Escuela Nacional de Estudios Profesionales Iztacala,
Licenciatura en Biología,
UNAM.
Total de publicaciones: 33
- Tipo
- Fecha
Artículo
3 - Alvarez-Salas,E., Alcantara-Alonso,V., Matamoros-Trejo,G., Vargas,M.A., Morales-Mulia,M., Gortari,P. (2015). Mediobasal hypothalamic and adenohypophyseal TRH-degrading enzyme (PPII) is down-regulated by zinc deficiency.
International Journal of Developmental Neuroscience,
46,
115-124.
Artículo
4 - Lazcano,I., Uribe,R.M., Martinez-Chavez,Erick, Vargas,M.A., Matziari,M., Joseph-Bravo,P., Charli,J.L. (2012). Pyroglutamyl peptidase II inhibition enhances the analeptic effect of thyrotropin releasing hormone in the rat medial septum.
Journal of Pharmacology and Experimental Therapeutics,
342 (1),
222-231.
Artículo
5 - Pascual,I., Gomez,H., Pons,T., Chappe,M., Vargas,M.A., Valdes,G., Lopez,A., Saroyan,A., Charli,J.L., Chavez,M.D. (2011). Effect of divalent cations on the porcine kidney cortex membrane-bound form of dipeptidyl peptidase IV.
International Journal of Biochemistry and Cell Biology,
43 (3),
363-371.
Artículo
6 - Uribe,R.M., Cisneros,M., Vargas,M.A., Lezama,L., Cote-Velez,A., Joseph-Bravo,P., Charli,J.L. (2011). The systemic inhibition of nitric oxide production rapidly regulates TRH mRNA concentration in the paraventricular nucleus of the hypothalamus and serum TSH concentration. Studies in control and cold-stressed rats.
Brain Research,
1367,
188-197.
Artículo
7 - Rodriguez-Molina,V., Vargas,M.A., Joseph-Bravo,P., Charli,J.L. (2009). NMDA receptor up-regulates pyroglutamyl peptidase II activity in the rat hippocampus.
Neuroscience Letters,
449 (3),
211-214.
Artículo
8 - Sanchez,E., Vargas,M.A., Singru,P.S., Pascual,I., Romero,F., Fekete,C., Charli,J.L., Lechan,R.M. (2009). Tanycyte Pyroglutamyl Peptidase II Contributes to Regulation of the Hypothalamic-Pituitary-Thyroid Axis through Glial-Axonal Associations in the Median Eminence.
Endocrinology,
150 (5),
2283-2291.
Artículo
9 - Cruz,R., Vargas,M.A., Uribe,R.M., Pascual,I., Lazcano,I., Yiotakis,A., Matziari,M., Joseph-Bravo,P., Charli,J.L. (2008). Anterior pituitary pyroglutamyl peptidase II activity controls TRH-induced prolactin release.
Peptides,
29 (11),
1953-1964.
Artículo
10 - de Gortari,P., Vargas,M.A., Martinez,A., Garcia-Vazquez,A.I., Uribe,R.M., Chavez-Gutierrez,L., Magdaleno,V., Boileau,G., Charli,J.L., Joseph-Bravo,P. (2007). Stage-specific Modulation of Neprilysin and Aminopeptidase N in the Limbic System During Kindling Progression.
Journal of Molecular Neuroscience,
33 (3),
252-261.
Artículo
11 - Chavez-Gutierrez,L., Bourdais,J., Aranda,G., Vargas,M.A., Matta-Camacho,E., Ducancel,F, Segovia,L., Joseph-Bravo,P., Charli,J.L. (2005). A truncated isoform of pyroglutamyl aminopeptidase II produced by exon extension has dominant-negative activity.
Journal of Neurochemistry,
92 (4),
807-817.
Artículo
12 - Benoit,A., Vargas,M.A., Desgroseillers,L., Boileau,G. (2004). Endothelin-converting enzyme-like 1 (ECEL1) is present both in the plasma membrane and in the endoplasmic reticulum.
Biochemical Journal,
380 (Pt 3),
881-888.
*
Artículo
13 - Vargas,M.A., St Louis,M., Desgroseillers,L., Charli,J.L., Boileau,G. (2003). Parathyroid Hormone-Related Protein(1-34) Regulates Phex Expression in Osteoblasts Through the Protein Kinase A Pathway.
Endocrinology,
144 (11),
4876-4885.
Artículo
14 - Vargas,M.A., Uribe,R.M., Cisneros,M., Romero,F., Gonzalez,S., Joseph-Bravo,P., Charli,J.L. (2002). Thyrotropin-releasing hormone regulates the diurnal variation of pyroglutamyl aminopeptidase II activity in the male rat adenohypophysis.
European Journal of Endocrinology,
147 (3),
363-369.
Artículo
15 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (2002). Thyrotropin-releasing hormone-induced down-regulation of pyroglutamyl aminopeptidase II activity involves L-type calcium channels and cam kinase activities in cultures of adenohypophyseal cells.
Journal of Neuroendocrinology,
14 (3),
184-193.
Artículo
16 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (2000). Regulation of adenohypophyseal pyroglutamyl aminopeptidase II activity by thyrotropin-releasing hormone and phorbol esters.
Endocrine,
13 (3),
267-272.
Artículo; Actas Paper
17 - Charli,J.L., Vargas,M.A., Cisneros,M., de Gortari,P., Baeza,M.A., Jasso,P., Bourdais,J., Perez,L., Uribe,R.M., Joseph-Bravo,P. (1998). TRH inactivation in the extracellular compartment: role of pyroglutamyl peptidase II.
Neurobiology (Bp.),
6 (1),
45-57.
Revisión
18 - Joseph-Bravo,P., Uribe,R.M., Vargas,M.A., Perez-Martinez,L., Zoeller,T., Charli,J.L. (1998). Multifactorial modulation of TRH metabolism.
Cellular & Molecular Neurobiology,
18 (2),
231-247.
Artículo
19 - Vargas,M.A., Bourdais,J., Sanchez,S., Uriostegui,B., Moreno,E., Joseph-Bravo,P., Charli,J.L. (1998). Multiple hypothalamic factors regulate pyroglutamyl peptidase II in cultures of adenohypophyseal cells: role of the cAMP pathway.
Journal of Neuroendocrinology,
10 (3),
199-206.
Artículo
20 - Covarrubias,L., Redondo,J.L., Vargas,M.A., Uribe,R.M., Mendez,M., Joseph-Bravo,P., Charli,J.L. (1994). In vitro TRH release from hypothalamus slices varies during the diurnal cycle.
Neurochemical Research,
19 (7),
845-850.
Artículo
21 - Joseph-Bravo,P., Fresan,M., Cisneros,M., Vargas,M.A., Charli,J.L. (1994). Pyroglutamyl peptidase II activity is not in the processes of bulbospinal TRHergic neurons.
Neuroscience Letters,
178 (2),
243-246.
Artículo
22 - Vargas,M.A., Joseph-Bravo,P., Charli,J.L. (1994). Thyrotropin-releasing hormone downregulates pyroglutamyl peptidase II activity in adenohypophyseal cells.
Neuroendocrinology,
60 (3),
323-330.
Artículo
23 - Vargas,M.A., Cisneros,M., Herrera,J., Joseph-Bravo,P., Charli,J.L. (1992). Regional distribution of pyroglutamyl peptidase II in rabbit brain, spinal cord, and organs.
Peptides,
13 (2),
255-260.
Artículo
24 - Cruz,C., Charli,J.L., Vargas,M.A., Joseph-Bravo,P. (1991). Neuronal localization of pyroglutamate aminopeptidase II in primary cultures of fetal mouse brain.
Journal of Neurochemistry,
56 (5),
1594-1601.
Artículo
25 - Charli,J.L., Cruz,C., Ponce,G., Vargas,M.A., Mendez,M., Cisneros,M., Pasten,J., Joseph-Bravo,P. (1989). Physiological relevance of pyroglutamate aminopeptidase II.
Annals of the New York Academy of Sciences,
553,
563-564.
Artículo
26 - Charli,J.L., Mendez,M., Vargas,M.A., Cisneros,M., Assai,M., Joseph-Bravo,P., Wilk,S. (1989). Pyroglutamyl peptidase II inhibition specifically increases recovery of TRH released from rat brain slices.
Neuropeptides,
14 (3),
191-196.
Artículo
27 - Charli,J.L., Cruz,C., Vargas,M., Joseph-Bravo,P. (1988). The narrow specificity pyroglutamate aminopeptidase degrading TRH in brain is an ectoenzyme.
Neurochemistry International,
13,
237-242.
Artículo
28 - Mendez,M., Joseph-Bravo,P., Cisneros,M., Vargas,M.A., Charli,J.L. (1987). Regional distribution of in vitro release of thyrotropin releasing hormone in rat brain.
Peptides,
8 (2),
291-298.
Artículo
29 - Vargas,M., Mendez,M., Cisneros,M., Joseph-Bravo,P., Charli,J.L. (1987). Regional distribution of the membrane-bound pyroglutamate amino peptidase-degrading thyrotropin-releasing hormone in rat brain.
Neuroscience Letters,
79 (3),
311-314.
Artículo
30 - Torres,H., Charli,J.L., Vargas,M.A., Gonzalez-Noriega,A., Joseph-Bravo,P. (1986). Subcellular distribution of the enzymes degrading Thyrotropin releasing hormone and metabolites in rat brain.
Neurochemistry International,
9,
103-110.
Internacional
31 - Charli,J.L., Pascual,I., Cruz,R., Vargas,M.A. (2006). Post-Secretory Inactivation of Peptides in the Hypotalamic-Adenohypophyseal Axis. Focus on Pyroglutamyl Peptidase Ii, the Thyrotropin Releasing Hormone Inactivating Enzyme. Molecular Endocrinology.
39-64,
Kerala, India: Research Signpost.
Note
32 - Vargas,M.A., Herrera,J., Uribe,R.M., Charli,J.L., Joseph-Bravo,P. (1992). Ontogenesis of pyroglutamyl peptidase II activity in rat brain, adenohypophysis and pancreas.
Developmental Brain Research,
66 (2),
251-256.
33 - Vargas Suarez, Miguel Angel (1998). Regulacion de la actividad de la piroglutamil peptidasa II en adenohipofisis : papel de la TRH .
Instituto de Biotecnologia,
Doctorado en Investigacion Biomedica Basica,
UNAM.
Asesor: Charli Casalonga, Jean Louis
34 - Vargas Suarez, Miguel Angel (1988). Relevancia fisiologica de una PGA membranal que degrada al TRH en el SNC de la rata.
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
Maestria en Investigacion Biomedica Basica,
UNAM.
Asesor: Charli Casalonga, Jean Louis
35 - Vargas Suarez, Miguel Angel (1986). Distribucion regional de una piroglutamato aminopeptidasa membranal que degrada la hormona liberadora de tirotropina en el sistema nervioso central de rata.
ENEP Iztacala,
Licenciatura en Biología,
UNAM.
Asesor: Charli Casalonga, Jean Louis
Artículo
36 - Alvarez-Salas,E., Alcantara-Alonso,V., Matamoros-Trejo,G., Vargas,M.A., Morales-Mulia,M., Gortari,P.. Mediobasal hypothalamic and adenohypophyseal TRH-degrading enzyme (PPII) is down-regulated by zinc deficiency.
International Journal of Developmental Neuroscience,
46,
115-124.
Artículo
37 - Lazcano,I., Uribe,R.M., Martinez-Chavez,Erick, Vargas,M.A., Matziari,M., Joseph-Bravo,P., Charli,J.L.. Pyroglutamyl peptidase II inhibition enhances the analeptic effect of thyrotropin releasing hormone in the rat medial septum.
Journal of Pharmacology and Experimental Therapeutics,
342 (1),
222-231.
Artículo
38 - Pascual,I., Gomez,H., Pons,T., Chappe,M., Vargas,M.A., Valdes,G., Lopez,A., Saroyan,A., Charli,J.L., Chavez,M.D.. Effect of divalent cations on the porcine kidney cortex membrane-bound form of dipeptidyl peptidase IV.
International Journal of Biochemistry and Cell Biology,
43 (3),
363-371.
Artículo
39 - Uribe,R.M., Cisneros,M., Vargas,M.A., Lezama,L., Cote-Velez,A., Joseph-Bravo,P., Charli,J.L.. The systemic inhibition of nitric oxide production rapidly regulates TRH mRNA concentration in the paraventricular nucleus of the hypothalamus and serum TSH concentration. Studies in control and cold-stressed rats.
Brain Research,
1367,
188-197.
Artículo
40 - Rodriguez-Molina,V., Vargas,M.A., Joseph-Bravo,P., Charli,J.L.. NMDA receptor up-regulates pyroglutamyl peptidase II activity in the rat hippocampus.
Neuroscience Letters,
449 (3),
211-214.
Artículo
41 - Sanchez,E., Vargas,M.A., Singru,P.S., Pascual,I., Romero,F., Fekete,C., Charli,J.L., Lechan,R.M.. Tanycyte Pyroglutamyl Peptidase II Contributes to Regulation of the Hypothalamic-Pituitary-Thyroid Axis through Glial-Axonal Associations in the Median Eminence.
Endocrinology,
150 (5),
2283-2291.
Artículo
42 - Cruz,R., Vargas,M.A., Uribe,R.M., Pascual,I., Lazcano,I., Yiotakis,A., Matziari,M., Joseph-Bravo,P., Charli,J.L.. Anterior pituitary pyroglutamyl peptidase II activity controls TRH-induced prolactin release.
Peptides,
29 (11),
1953-1964.
Artículo
43 - de Gortari,P., Vargas,M.A., Martinez,A., Garcia-Vazquez,A.I., Uribe,R.M., Chavez-Gutierrez,L., Magdaleno,V., Boileau,G., Charli,J.L., Joseph-Bravo,P.. Stage-specific Modulation of Neprilysin and Aminopeptidase N in the Limbic System During Kindling Progression.
Journal of Molecular Neuroscience,
33 (3),
252-261.
Internacional
44 - Charli,J.L., Pascual,I., Cruz,R., Vargas,M.A.. Post-Secretory Inactivation of Peptides in the Hypotalamic-Adenohypophyseal Axis. Focus on Pyroglutamyl Peptidase Ii, the Thyrotropin Releasing Hormone Inactivating Enzyme. Molecular Endocrinology.
39-64,
Kerala, India: Research Signpost.
Artículo
45 - Chavez-Gutierrez,L., Bourdais,J., Aranda,G., Vargas,M.A., Matta-Camacho,E., Ducancel,F, Segovia,L., Joseph-Bravo,P., Charli,J.L.. A truncated isoform of pyroglutamyl aminopeptidase II produced by exon extension has dominant-negative activity.
Journal of Neurochemistry,
92 (4),
807-817.
Artículo
46 - Benoit,A., Vargas,M.A., Desgroseillers,L., Boileau,G.. Endothelin-converting enzyme-like 1 (ECEL1) is present both in the plasma membrane and in the endoplasmic reticulum.
Biochemical Journal,
380 (Pt 3),
881-888.
*
Artículo
47 - Vargas,M.A., St Louis,M., Desgroseillers,L., Charli,J.L., Boileau,G.. Parathyroid Hormone-Related Protein(1-34) Regulates Phex Expression in Osteoblasts Through the Protein Kinase A Pathway.
Endocrinology,
144 (11),
4876-4885.
Artículo
48 - Vargas,M.A., Uribe,R.M., Cisneros,M., Romero,F., Gonzalez,S., Joseph-Bravo,P., Charli,J.L.. Thyrotropin-releasing hormone regulates the diurnal variation of pyroglutamyl aminopeptidase II activity in the male rat adenohypophysis.
European Journal of Endocrinology,
147 (3),
363-369.
Artículo
49 - Vargas,M.A., Cisneros,M., Joseph-Bravo,P., Charli,J.L.. Thyrotropin-releasing hormone-induced down-regulation of pyroglutamyl aminopeptidase II activity involves L-type calcium channels and cam kinase activities in cultures of adenohypophyseal cells.
Journal of Neuroendocrinology,
14 (3),
184-193.
Artículo
Artículo; Actas Paper
51 - Charli,J.L., Vargas,M.A., Cisneros,M., de Gortari,P., Baeza,M.A., Jasso,P., Bourdais,J., Perez,L., Uribe,R.M., Joseph-Bravo,P.. TRH inactivation in the extracellular compartment: role of pyroglutamyl peptidase II.
Neurobiology (Bp.),
6 (1),
45-57.
Revisión
52 - Joseph-Bravo,P., Uribe,R.M., Vargas,M.A., Perez-Martinez,L., Zoeller,T., Charli,J.L.. Multifactorial modulation of TRH metabolism.
Cellular & Molecular Neurobiology,
18 (2),
231-247.
Artículo
53 - Vargas,M.A., Bourdais,J., Sanchez,S., Uriostegui,B., Moreno,E., Joseph-Bravo,P., Charli,J.L.. Multiple hypothalamic factors regulate pyroglutamyl peptidase II in cultures of adenohypophyseal cells: role of the cAMP pathway.
Journal of Neuroendocrinology,
10 (3),
199-206.
54 - Vargas Suarez, Miguel Angel. Regulacion de la actividad de la piroglutamil peptidasa II en adenohipofisis : papel de la TRH .
Instituto de Biotecnologia,
Doctorado en Investigacion Biomedica Basica,
UNAM.
Asesor: Charli Casalonga, Jean Louis
Artículo
55 - Covarrubias,L., Redondo,J.L., Vargas,M.A., Uribe,R.M., Mendez,M., Joseph-Bravo,P., Charli,J.L.. In vitro TRH release from hypothalamus slices varies during the diurnal cycle.
Neurochemical Research,
19 (7),
845-850.
Artículo
56 - Joseph-Bravo,P., Fresan,M., Cisneros,M., Vargas,M.A., Charli,J.L.. Pyroglutamyl peptidase II activity is not in the processes of bulbospinal TRHergic neurons.
Neuroscience Letters,
178 (2),
243-246.
Artículo
57 - Vargas,M.A., Joseph-Bravo,P., Charli,J.L.. Thyrotropin-releasing hormone downregulates pyroglutamyl peptidase II activity in adenohypophyseal cells.
Neuroendocrinology,
60 (3),
323-330.
Artículo
58 - Vargas,M.A., Cisneros,M., Herrera,J., Joseph-Bravo,P., Charli,J.L.. Regional distribution of pyroglutamyl peptidase II in rabbit brain, spinal cord, and organs.
Peptides,
13 (2),
255-260.
Note
59 - Vargas,M.A., Herrera,J., Uribe,R.M., Charli,J.L., Joseph-Bravo,P.. Ontogenesis of pyroglutamyl peptidase II activity in rat brain, adenohypophysis and pancreas.
Developmental Brain Research,
66 (2),
251-256.
Artículo
60 - Cruz,C., Charli,J.L., Vargas,M.A., Joseph-Bravo,P.. Neuronal localization of pyroglutamate aminopeptidase II in primary cultures of fetal mouse brain.
Journal of Neurochemistry,
56 (5),
1594-1601.
Artículo
61 - Charli,J.L., Cruz,C., Ponce,G., Vargas,M.A., Mendez,M., Cisneros,M., Pasten,J., Joseph-Bravo,P.. Physiological relevance of pyroglutamate aminopeptidase II.
Annals of the New York Academy of Sciences,
553,
563-564.
Artículo
62 - Charli,J.L., Mendez,M., Vargas,M.A., Cisneros,M., Assai,M., Joseph-Bravo,P., Wilk,S.. Pyroglutamyl peptidase II inhibition specifically increases recovery of TRH released from rat brain slices.
Neuropeptides,
14 (3),
191-196.
Artículo
63 - Charli,J.L., Cruz,C., Vargas,M., Joseph-Bravo,P.. The narrow specificity pyroglutamate aminopeptidase degrading TRH in brain is an ectoenzyme.
Neurochemistry International,
13,
237-242.
64 - Vargas Suarez, Miguel Angel. Relevancia fisiologica de una PGA membranal que degrada al TRH en el SNC de la rata.
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
Maestria en Investigacion Biomedica Basica,
UNAM.
Asesor: Charli Casalonga, Jean Louis
Artículo
65 - Mendez,M., Joseph-Bravo,P., Cisneros,M., Vargas,M.A., Charli,J.L.. Regional distribution of in vitro release of thyrotropin releasing hormone in rat brain.
Peptides,
8 (2),
291-298.
Artículo
66 - Vargas,M., Mendez,M., Cisneros,M., Joseph-Bravo,P., Charli,J.L.. Regional distribution of the membrane-bound pyroglutamate amino peptidase-degrading thyrotropin-releasing hormone in rat brain.
Neuroscience Letters,
79 (3),
311-314.
Artículo
67 - Torres,H., Charli,J.L., Vargas,M.A., Gonzalez-Noriega,A., Joseph-Bravo,P.. Subcellular distribution of the enzymes degrading Thyrotropin releasing hormone and metabolites in rat brain.
Neurochemistry International,
9,
103-110.
68 - Vargas Suarez, Miguel Angel. Distribucion regional de una piroglutamato aminopeptidasa membranal que degrada la hormona liberadora de tirotropina en el sistema nervioso central de rata.
ENEP Iztacala,
Licenciatura en Biología,
UNAM.
Asesor: Charli Casalonga, Jean Louis