Bioinformática aplicada a las ciencias ómicas
Número de registros: 9
  • Vencidos
  • Regulación de la expresión genética a nivel global en bacterias, PRESUPUESTO UNAM, 2014 - 2020
  • Estudios de regulación de la expresión genética a nivel global en escherichia coli y geobacter sulfurreducens utilizando estrategias de secuenciación masiva y herramientas bioinformáticas, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2012 - 2016
  • Desarrollo de metodologías robustas para el mapeo global de sitios de inicio de la transcripción en escherichia coli y geobacter sulfurreducens mediante secuenciación masiva de extremos 5´trifosfato de los mrna, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2012 - 2014
  • Mapeo global de sitios de inicio de transcripción en escherichia coli y otras bacterias por pirosecuenciación, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2009 - 2012
  • Evolución de las actividades enzimáticas involucradas en la biosíntesis de biotina, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2008 - 2010
  • Estudios estructurales de variantes de hema con actividad de biof obtenidas por evolución dirigida., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2006
  • Evolución de nuevas actividades enzimáticas: implementación de sistemas de selección eficientes para demostrar migración catalítica., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2002 - 2005
  • Migración de actividad enzimática por medio de evolución dirigida en un sistema de selección muy sensible, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1999 - 2002
  • Análisis genético de las interacciones moleculares durante la iniciación de la transcripción de bacterias: modificación del factor transcripcional sigma-54, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1997 - 1998

Nivel Investigador Emérito del SNII
  • Doctorado, en Bioquímica, Universidad de Sussex, Laboratorio de Fijacion de Nitrogeno

  • Maestría, en Investigacion Biomedica Basica, UNAM (1986)

  • Licenciatura, Investigacion Biomedica Basica, UNAM (1984)

4 - Sanchez Sanchez, Brenda Janice (2012). Estandarizacion de una metodologia para la identificacion de sitios de inicio de la transcripcion dependientes de s70, en escherichia coli k12, mediante mapeo transcripcional in vitro. Instituto de Biotecnologia, Maestria en Ciencias Bioquimicas, UNAM.
* Indica publicación con otra institución de adscripción
Total de publicaciones: 81
  • Tipo
  • Fecha
Open Access Artículo
18 - Miron-Toruno,F., Morett,E., Aguilar-Ordonez,I., Reynolds,A.W. (2025). Genome-wide selection scans in Mexican Indigenous populations reveal recent signatures of pathogen and diet adaptation. Genome Biology and Evolution, 17 (3), evaf043.
Open Access Revisión
19 - Perez-Gonzalez,A.P., Aguilar-Ordonez,I., Caballero,N.A., Morett,E. (2025). Genetic and genomic insights of the Comcáac people. Journal of Community Genetics, 16, 653?668.
Open Access Artículo
20 - Mier,P., Andrade-Navarro,M.A., Morett,E. (2024). Homorepeat variability within the human population. NAR genomics and bioinformatics, 6 (2), lqae053.
Open Access Revisión
21 - Aguilar-Ordonez,I., Guzman-Linares,J., Ballesteros-Villascan,J., Miron-Toruno,F., Perez-Gonzalez,A., Garcia-Lopez,J., Cruz-Lopez,F., Morett,E. (2022). A Tale of Native American Whole-Genome Sequencing and Other Technologies. Diversity, 14 (8), 647.
Open Access Artículo
22 - Aguilar-Ordonez,I., Perez-Villatoro,F., Garcia-Ortiz,H., Barajas-Olmos,F., Ballesteros-Villascan,J., Gonzalez-Buenfil,R., Fresno,C., Garciarrubio,A., Fernandez-Lopez,J.C., Tovar,H., Hernandez-Lemus,E., Orozco,L., Soberon,X., Morett,E. (2021). Whole genome variation in 27 Mexican indigenous populations, demographic and biomedical insights. PLoS ONE, 16 (4), e0249773, [correction May 25 2022].
Open Access Artículo
24 - Lara,P., Vega-Alvarado,L., Sahonero-Canavesi,D.X., Koenen,M., Villanueva,L., Riveros-McKay,F., Morett,E., Juarez,K. (2021). Transcriptome Analysis Reveals Cr(VI) Adaptation Mechanisms in Klebsiella sp. Strain AqSCr. Frontiers in Microbiology, 12, 656589.
Open Access Artículo
26 - Jasso-Chavez,R., Lira-Silva,E., Gonzalez-Sanchez,K., Larios-Serrato,V., Mendoza-Monzoy,D.L., Perez-Villatoro,F., Morett,E., Vega-Segura,A., Torres-Marquez,M.E., Zepeda-Rodriguez,A., Moreno-Sanchez,R. (2019). Marine Archaeon Methanosarcina acetivorans Enhances Polyphosphate Metabolism Under Persistent Cadmium Stress. Frontiers in Microbiology, 10, 2432.
Artículo; Actas Paper
Open Access Artículo
29 - Romero-Hidalgo, S., Ochoa-Leyva, A., Garciarrubio, A., Acuna-Alonzo, V., Antunez-Arguelles, E., Balcazar-Quintero, M., Barquera-Lozano, R., Carnevale, A., Cornejo-Granados, F., Fernandez-Lopez, J.C., Garcia-Herrera, R., Garcia-Ortiz, H., Granados-Silvestre, A., Granados, J., Guerrero-Romero, F., Hernandez-Lemus, E., Leon-Mimila, P., Macin-Perez, G., Martinez-Hernandez, A., Menjivar, M., Morett, E., Orozco, L., Ortiz-Lopez, G., Perez-Villatoro, F., Rivera-Morales, J., Riveros-McKay, F., Villalobos-Comparan, M., Villamil-Ramirez, H., Villarreal-Molina, T., Canizales-Quinteros, S., Soberon, X. (2017). Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing. Nature Communications, 8 (1), 1005.
Open Access Artículo
Open Access Artículo
32 - Meysman,P., Collado-Vides,J., Morett,E., Viola,R., Engelen,K., Laukens,K. (2014). Structural properties of prokaryotic promoter regions correlate with functional features. PLoS ONE, 9 (2), e88717.
Open Access Artículo
33 - Balderas-Martinez,Y.I., Savageau,M., Salgado,H., Perez-Rueda,E., Morett,E., Collado-Vides,J. (2013). Transcription Factors in Escherichia coli Prefer the Holo Conformation. PLoS ONE, 8 (6), e65723.
Open Access Artículo
34 - Salgado,H., Peralta-Gil,M., Gama-Castro,S., Santos-Zavaleta,A., Muniz-Rascado,L., Garcia-Sotelo,J.S., Weiss,V., Solano-Lira,H., Martinez-Flores,I., Medina-Rivera,A., Salgado-Osorio,G., Alquicira-Hernandez,S., Alquicira-Hernandez,K., Lopez-Fuentes,A., Porron-Sotelo,L., Huerta,A.M., Bonavides-Martinez,C., Balderas-Martinez,Y.I., Pannier,L., Olvera,M., Labastida,A., Jimenez-Jacinto,V., Vega-Alvarado,L., Del Moral-Chavez,V., Hernandez-Alvarez,A., Morett,E., Collado-Vides,J. (2013). RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more. Nucleic Acids Research, 41 (D1), D203-D213.
Artículo
35 - Weiss,V., Medina-Rivera,A., Huerta,A.M., Santos-Zavaleta,A., Salgado,H., Morett,E., Collado-Vides,J. (2013). Evidence classification of high-throughput protocols and confidence integration in RegulonDB. Database (Oxford), 2013, bas059.
Open Access Artículo
37 - Flores,H., Lin,S., Contreras-Ferrat,G., Cronan,J.E., Morett,E. (2012). Evolution of a new function in an esterase: simple amino acid substitutions enable the activity present in the larger paralog, BioH. Protein Engineering Design & Selection, 25 (8), 387-395.
Open Access Artículo
38 - Gallego-Hernandez,A.L., Hernandez-Lucas,I., De la Cruz,M.A., Olvera,L., Morett,E., Medina-Aparicio,L., Ramirez-Trujillo,J.A., Vazquez,A., Fernandez-Mora,M., Calva,E. (2012). Transcriptional regulation of the assT-dsbL-dsbI gene cluster depends on LeuO, H-NS and specific growth conditions in Salmonella enterica serovar Typhi IMSS-1. Journal of Bacteriology, 194 (9), 2254-2264.
Open Access Artículo
40 - Gama-Castro,S., Salgado,H., Peralta-Gil,M., Santos-Zavaleta,A., Muniz-Rascado,L., Solano-Lira,H., Jimenez-Jacinto,V., Weiss,V., Garcia-Sotelo,J.S., Lopez-Fuentes,A., Porron-Sotelo,L., Alquicira-Hernandez,S., Medina-Rivera,A., Martinez-Flores,I., Alquicira-Hernandez,K., Martinez-Adame,R., Bonavides-Martinez,C., Miranda-Rios,J., Huerta,A.M., Mendoza-Vargas,A., Collado-Torres,L., Taboada,B., Vega-Alvarado,L., Olvera,M., Olvera,L., Grande,R., Morett,E., Collado-Vides,J. (2011). RegulonDB version 7.0: transcriptional regulation of Escherichia coli K-12 integrated within genetic sensory response units (Gensor Units). Nucleic Acids Research, 39 (Suppl 1), D98-D105.
Open Access Artículo
41 - Massimelli,M.J., Sanchez,D.G., Buchieri,M.V., Olvera,L., Beassoni,P.R., Schweizer,H.P., Morett,E., Lisa,A.T. (2011). Choline catabolism, sigma(54) factor and NtrC are required for the full expression of the Pseudomonas aeruginosa phosphorylcholine phosphatase gene. Microbiological Research, 166 (5), 380-390.
Open Access Revisión
42 - Collado-Vides,J., Salgado,H., Morett,E., Gama-Castro,S., Jimenez-Jacinto,V., Martinez-Flores,I., Medina-Rivera,A., Muniz-Rascado,L., Peralta-Gil,M., Santos-Zavaleta,A. (2009). Bioinformatics resources for the study of gene regulation in bacteria. Journal of Bacteriology, 191 (1), 23-31.
Open Access Artículo
43 - Mendoza-Vargas,A., Olvera,L., Olvera,M., Grande,R., Vega-Alvarado,L., Taboada,B., Jimenez-Jacinto,V., Salgado,H., Juarez,K., Contreras-Moreira,B., Huerta,A.M., Collado-Vides,J., Morett,E. (2009). Genome-Wide Identification of Transcription Start Sites, Promoters and Transcription Factor Binding Sites in E. coli. PLoS ONE, 4 (10), e7526.
Open Access Artículo
45 - Gama-Castro,S., Jimenez-Jacinto,V., Peralta-Gil,M., Santos-Zavaleta,A., Penaloza-Spinola,M.I., Contreras-Moreira,B., Segura-Salazar,J., Muniz-Rascado,L., Martinez-Flores,I., Salgado,H., Bonavides-Martinez,C., Abreu-Goodger,C., Rodriguez-Penagos,C., Miranda-Rios,J., Morett,E., Merino,E., Huerta,A.M., Trevino-Quintanilla,L., Collado-Vides,J. (2008). RegulonDB (version 6.0): gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation. Nucleic Acids Research, 36 (Database issue), D120-D124.
Open Access Artículo
47 - Watanabe,R.L., Morett,E., Vallejo,E.E. (2008). Inferring modules of functionally interacting proteins using the Bond Energy Algorithm. BMC Bioinformatics, 9 (1), 285.
Open Access Artículo
48 - Dago,A.E., Wigneshweraraj,S.R., Buck,M., Morett,E. (2007). A role for the conserved GAFTGA motif of AAA transcriptional activators in sensing promoter DNA conformation. Journal of Biological Chemistry, 282 (2), 1087-1097.
Artículo
49 - Hernandez-Urzua,E., Zamorano-Sanchez,D.S., Ponce-Coria,J., Morett,E., Grogan,S., Poole,R.K., Membrillo-Hernandez,J. (2007). Multiple regulators of the Flavohaemoglobin (hmp) gene of Salmonella enterica serovar Typhimurium include RamA, a transcriptional regulator conferring the multidrug resistance phenotype. Archives of Microbiology, 187 (1), 67-77.
Artículo; Actas Paper
50 - Aguilar-Diaz,H., Bobes,R.J., Carrero,J.C., Camacho-Carranza,R., Cervantes,C., Cevallos,M.A., Davila,G., Rodriguez-Dorantes,M., Escobedo,G., Fernandez,J.L., Fragoso,G., Gaytan,P., Garciarrubio,A., Gonzalez,V.M., Gonzalez,L., Jose,M.V., Jimenez,L., Laclette,J.P., Landa,A., Larralde,C., Morales-Montor,J., Morett,E., Ostoa-Saloma,P., Sciutto,E., Santamaria,R.I., Soberon,X., de la Torre P., Valdes,V., Yanez,J. (2006). The genome project of Taenia solium. Parasitology International, 55 (Suppl), S127-S130.
Open Access Artículo
51 - Avonce,N., Mendoza-Vargas,A., Morett,E., Iturriaga,G. (2006). Insights on the evolution of trehalose biosynthesis. BMC Evolutionary Biology, 6 (1), 109.
Open Access Artículo
52 - Huerta,A.M., Francino,M.P., Morett,E., Collado-Vides,J. (2006). Selection for Unequal Densities of sigma(70) Promoter-Like Signals in Different Regions of Large Bacterial Genomes. PLoS Genetics, 2 (11), e185.
Artículo
53 - Gaytan,P., Yanez,J., Grande,R., Morett,E., Soberon,X. (2005). Improving random mutagenesis by purification of the oligonucleotide variants. Combinatorial Chemistry & High Throughput Screening, 8 (6), 537-544.
Artículo
55 - Ciria,R., Abreu-Goodger,C., Morett,E., Merino,E. (2004). GeConT: gene context analysis. Bioinformatics, 20 (14), 2307-2308.
Artículo
57 - Morett,E., Korbel,J.O., Rajan,E., Saab-Rincon,G., Olvera,L., Olvera,M., Schmidt,S., Snel,B., Bork,P. (2003). Systematic discovery of analogous enzymes in thiamin biosynthesis. Nature Biotechnology, 21 (7), 790-795.
Open Access Artículo; Actas
58 - Morett,E., Korbel,J.O., Rajan,E., Saab-Rincon,G., Olvera,L., Olvera,M., Schmidt,S., Snel,B., Bork,P. (2002). Discovery of Analogous Enzymes in Thiamin Biosynthesis by Anticorrelation. Genome Informatics, 13, 365-366.
Artículo
59 - Chaney,M., Grande,R., Wigneshweraraj,S.R., Cannon,W., Casaz,P., Gallegos,M.T., Schumacher,J., Jones,S., Elderkin,S., Dago,A.E., Morett,E., Buck,M. (2001). Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action. Genes and Development, 15 (17), 2282-2294.
Artículo
60 - Juarez,K., Flores,H., Davila,S., Olvera,L., Gonzalez,V., Morett,E. (2000). Reciprocal domain evolution within a transactivator in a restricted sequence space. Proceedings of the National Academy of Sciences of the United States of America, 97 (7), 3314-3318.
Open Access Revisión
Artículo
63 - Morett,E., Bork,P. (1999). A novel transactivation domain in parkin. Trends in Biochemical Sciences, 24 (6), 229-231.
Artículo
Open Access Artículo
69 - Valderrama,B., Davalos,A., Girard,L., Morett,E., Mora,J. (1996). Regulatory proteins and cis-acting elements involved in the transcriptional control of Rhizobium etli reiterated nifH genes. Journal of Bacteriology, 178 (11), 3119-3126.
Open Access Artículo
70 - Barrios,H., Fischer,H.M., Hennecke,H., Morett,E. (1995). Overlapping promoters for two different RNA polymerase holoenzymes control Bradyrhizobium japonicum nifA expression. Journal of Bacteriology, 177 (7), 1760-1765. *
Open Access Artículo
72 - Morett,E., Fischer,H.M., Hennecke,H. (1991). Influence of oxygen on DNA binding, positive control, and stability of the Bradyrhizobium japonicum NifA regulatory protein. Journal of Bacteriology, 173 (11), 3478-3487. *
Open Access Artículo
73 - Cannon,W.V., Kreutzer,R., Kent,H.M., Morett,E., Buck,M. (1990). Activation of the Klebsiella pneumoniae nifU promoter: identification of multiple and overlapping upstream NifA binding sites. Nucleic Acids Research, 18 (7), 1693-1701. *
Artículo
74 - Morett,E., Kreutzer,R., Cannon,W., Buck,M. (1990). The influence of the Klebsiella pneumoniae regulatory gene nifL upon the transcriptional activator protein NifA. Molecular Microbiology, 4 (8), 1253-1258. *
Artículo
76 - Morett,E., Moreno,S., Espin,G. (1988). Transcription analysis of the three nifH genes of Rhizobium phaseoli with gene fusions. MGG Molecular & General Genetics, 213 (2-3), 499-504. *
Open Access Artículo
78 - Morett,E., Buck,M. (1988). NifA-dependent in vivo protection demonstrates that the upstream activator sequence of nif promoters is a protein binding site. Proceedings of the National Academy of Sciences of the United States of America, 85 (24), 9401-9405. *
Note
79 - Romero,D., Singleton,P.W., Segovia,L., Morett,E., Benbohlool,B., Palacios,R., Davila,G. (1988). Effect of Naturally Occurring nif Reiterations on Symbiotic Effectiveness in Rhizobium phaseoli. Applied and Environmental Microbiology, 54 (3), 848-850. *
Open Access Note
80 - Calderon,J., Morett,E., Mora,J. (1985). Omega-amidase pathway in the degradation of glutamine in Neurospora crassa. Journal of Bacteriology, 161 (2), 807-809. *
Nacional
82 - Gonzalez,G., Labastida,A., Jimenez,V., Vega,L., Olvera,M., Morett,E., Juarez,K. (2015). Genes involved in electron transfer mechanism in g. Sulfurreducens. Environmental Biotechnology and Engineering-2014. 1269-1276, 3, Mexico D.F..
Internacional
84 - Tapia,J.J., Morett,E., Vallejo,E.E. (2009). A clustering genetic algorithm for genomic data mining. Foundations of Computational Intelligence . Studies in Computational Intelligence, 249-275, 4, Berlin, Heidelberg: Springer.
Memoria in extenso
85 - Tapia,J.J., Vallejo,E.E., Morett,E. (2009). MOCEA: A multi-objective clustering evolutionary algorithm for inferring protein-protein functional interactions. Proceedings of the 11th Annual Genetic and Evolutionary Computation Conference, GECCO-2009. 1793-1794.
Memoria in extenso
86 - Molina-Lozano,H., Vallejo-Clemente,E.E., Morett-Sanchez,J.E. (2008). DNA sequence analysis using fuzzy grammars. IEEE International Conference on Fuzzy Systems. 1915-1921.
Memoria in extenso
87 - Martínez,M., Vallejo,E.E., Morett,E. (2007). Ancestral DNA sequence reconstruction using recursive genetic algorithms. Lecture Notes in Computer Science, vol 4828 cap 4. 390-400.
Memoria in extenso
88 - Fernandez,J.C., Vallejo,E.E., Morett,E. (2006). Fuzzy C-means for inferring functional coupling of proteins from their phylogenetic profiles. Computational Intelligence and Bioinformatics and Computational Biology, 2006. CIBCB '06. 2006 IEEE Symposium on. 1-8.
Memoria in extenso
89 - Watanabe,R., Vallejo,E.E., Morett,E. (2006). Inferring functional coupling of proteins using the Evolutionary Bond Energy Algorithm. Proceedings of the 2006 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB'06. 400-405.
Internacional
90 - Morett,E., Saab-Rincon,G., Merino,E., Bork,P., Rajan,E., Olvera,L., Olvera,M. (2003). High rate of gene displacement in vitamin biosynthesis pathways. Bioinformatics and genomes: current perspectives. 69-79, Norfolk,U.K..
Nacional
91 - Morett,E. (2001). Genetic regulation of nitrogen fixation: from ammonia ssimilation to protein evolution. Nitrogen Fixation Research Center XX Anniversary. 180-183.
Internacional
92 - Morett,E., Juarez,K., Davila,S., Olvera,L., Caro,S., Flores,H. (1998). Enhancing Nitrogen Fixation Gene Expression by Modifying the DNA-Binding Function of Rhizobium meliloti NifA. Biological Nitrogen Fixation for the 21st Century. Dordrecht, Holanda: Kluwer Academic Publishers.
Nacional divulgación
93 - Morett-Sanchez,J.E. (2025). Racismo vs genómica: ¿Es científicamente válido hablar de razas en la población humana?. Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 10 (39).
Preprint
94 - Miron-Toruno,M.F., Morett,E., Aguilar-Ordonez,I., Reynolds,A.W. (2024). Whole genome sequencing of 76 Mexican Indigenous reveals recent selection signatures linked to pathogens and diet adaptation. bioRxiv, Preprint posted July 29.
Open Access nacional divulgación
95 - Aguilar,I., Guzman,J., Miron,F., Morett,E. (2021). Conociendo el Genoma Indígena Mexicano: el proyecto 100G-MX. Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 26, 8-15.
Open Access Artículo
Open Access Artículo
99 - Miron-Toruno,F., Morett,E., Aguilar-Ordonez,I., Reynolds,A.W.. Genome-wide selection scans in Mexican Indigenous populations reveal recent signatures of pathogen and diet adaptation. Genome Biology and Evolution, 17 (3), evaf043.
Open Access Revisión
100 - Perez-Gonzalez,A.P., Aguilar-Ordonez,I., Caballero,N.A., Morett,E.. Genetic and genomic insights of the Comcáac people. Journal of Community Genetics, 16, 653?668.
Nacional divulgación
101 - Morett-Sanchez,J.E.. Racismo vs genómica: ¿Es científicamente válido hablar de razas en la población humana?. Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 10 (39).
Open Access Artículo
102 - Mier,P., Andrade-Navarro,M.A., Morett,E.. Homorepeat variability within the human population. NAR genomics and bioinformatics, 6 (2), lqae053.
Preprint
103 - Miron-Toruno,M.F., Morett,E., Aguilar-Ordonez,I., Reynolds,A.W.. Whole genome sequencing of 76 Mexican Indigenous reveals recent selection signatures linked to pathogens and diet adaptation. bioRxiv, Preprint posted July 29.
Open Access Revisión
104 - Aguilar-Ordonez,I., Guzman-Linares,J., Ballesteros-Villascan,J., Miron-Toruno,F., Perez-Gonzalez,A., Garcia-Lopez,J., Cruz-Lopez,F., Morett,E.. A Tale of Native American Whole-Genome Sequencing and Other Technologies. Diversity, 14 (8), 647.
Open Access Artículo
105 - Aguilar-Ordonez,I., Perez-Villatoro,F., Garcia-Ortiz,H., Barajas-Olmos,F., Ballesteros-Villascan,J., Gonzalez-Buenfil,R., Fresno,C., Garciarrubio,A., Fernandez-Lopez,J.C., Tovar,H., Hernandez-Lemus,E., Orozco,L., Soberon,X., Morett,E.. Whole genome variation in 27 Mexican indigenous populations, demographic and biomedical insights. PLoS ONE, 16 (4), e0249773, [correction May 25 2022].
Open Access Artículo
Open Access Artículo
107 - Lara,P., Vega-Alvarado,L., Sahonero-Canavesi,D.X., Koenen,M., Villanueva,L., Riveros-McKay,F., Morett,E., Juarez,K.. Transcriptome Analysis Reveals Cr(VI) Adaptation Mechanisms in Klebsiella sp. Strain AqSCr. Frontiers in Microbiology, 12, 656589.
Open Access Artículo
Open Access nacional divulgación
109 - Aguilar,I., Guzman,J., Miron,F., Morett,E.. Conociendo el Genoma Indígena Mexicano: el proyecto 100G-MX. Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 26, 8-15.
Open Access Artículo
110 - Jasso-Chavez,R., Lira-Silva,E., Gonzalez-Sanchez,K., Larios-Serrato,V., Mendoza-Monzoy,D.L., Perez-Villatoro,F., Morett,E., Vega-Segura,A., Torres-Marquez,M.E., Zepeda-Rodriguez,A., Moreno-Sanchez,R.. Marine Archaeon Methanosarcina acetivorans Enhances Polyphosphate Metabolism Under Persistent Cadmium Stress. Frontiers in Microbiology, 10, 2432.
Artículo; Actas Paper
Artículo; Actas Paper
Open Access Artículo
113 - Romero-Hidalgo, S., Ochoa-Leyva, A., Garciarrubio, A., Acuna-Alonzo, V., Antunez-Arguelles, E., Balcazar-Quintero, M., Barquera-Lozano, R., Carnevale, A., Cornejo-Granados, F., Fernandez-Lopez, J.C., Garcia-Herrera, R., Garcia-Ortiz, H., Granados-Silvestre, A., Granados, J., Guerrero-Romero, F., Hernandez-Lemus, E., Leon-Mimila, P., Macin-Perez, G., Martinez-Hernandez, A., Menjivar, M., Morett, E., Orozco, L., Ortiz-Lopez, G., Perez-Villatoro, F., Rivera-Morales, J., Riveros-McKay, F., Villalobos-Comparan, M., Villamil-Ramirez, H., Villarreal-Molina, T., Canizales-Quinteros, S., Soberon, X.. Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing. Nature Communications, 8 (1), 1005.
Nacional
115 - Gonzalez,G., Labastida,A., Jimenez,V., Vega,L., Olvera,M., Morett,E., Juarez,K.. Genes involved in electron transfer mechanism in g. Sulfurreducens. Environmental Biotechnology and Engineering-2014. 1269-1276, 3, Mexico D.F..
Nacional
Open Access Artículo
Open Access Artículo
118 - Meysman,P., Collado-Vides,J., Morett,E., Viola,R., Engelen,K., Laukens,K.. Structural properties of prokaryotic promoter regions correlate with functional features. PLoS ONE, 9 (2), e88717.
Open Access Artículo
119 - Balderas-Martinez,Y.I., Savageau,M., Salgado,H., Perez-Rueda,E., Morett,E., Collado-Vides,J.. Transcription Factors in Escherichia coli Prefer the Holo Conformation. PLoS ONE, 8 (6), e65723.
Open Access Artículo
120 - Salgado,H., Peralta-Gil,M., Gama-Castro,S., Santos-Zavaleta,A., Muniz-Rascado,L., Garcia-Sotelo,J.S., Weiss,V., Solano-Lira,H., Martinez-Flores,I., Medina-Rivera,A., Salgado-Osorio,G., Alquicira-Hernandez,S., Alquicira-Hernandez,K., Lopez-Fuentes,A., Porron-Sotelo,L., Huerta,A.M., Bonavides-Martinez,C., Balderas-Martinez,Y.I., Pannier,L., Olvera,M., Labastida,A., Jimenez-Jacinto,V., Vega-Alvarado,L., Del Moral-Chavez,V., Hernandez-Alvarez,A., Morett,E., Collado-Vides,J.. RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more. Nucleic Acids Research, 41 (D1), D203-D213.
Artículo
121 - Weiss,V., Medina-Rivera,A., Huerta,A.M., Santos-Zavaleta,A., Salgado,H., Morett,E., Collado-Vides,J.. Evidence classification of high-throughput protocols and confidence integration in RegulonDB. Database (Oxford), 2013, bas059.
Open Access Artículo
Open Access Artículo
123 - Flores,H., Lin,S., Contreras-Ferrat,G., Cronan,J.E., Morett,E.. Evolution of a new function in an esterase: simple amino acid substitutions enable the activity present in the larger paralog, BioH. Protein Engineering Design & Selection, 25 (8), 387-395.
Open Access Artículo
124 - Gallego-Hernandez,A.L., Hernandez-Lucas,I., De la Cruz,M.A., Olvera,L., Morett,E., Medina-Aparicio,L., Ramirez-Trujillo,J.A., Vazquez,A., Fernandez-Mora,M., Calva,E.. Transcriptional regulation of the assT-dsbL-dsbI gene cluster depends on LeuO, H-NS and specific growth conditions in Salmonella enterica serovar Typhi IMSS-1. Journal of Bacteriology, 194 (9), 2254-2264.
Artículo
Open Access Artículo
126 - Gama-Castro,S., Salgado,H., Peralta-Gil,M., Santos-Zavaleta,A., Muniz-Rascado,L., Solano-Lira,H., Jimenez-Jacinto,V., Weiss,V., Garcia-Sotelo,J.S., Lopez-Fuentes,A., Porron-Sotelo,L., Alquicira-Hernandez,S., Medina-Rivera,A., Martinez-Flores,I., Alquicira-Hernandez,K., Martinez-Adame,R., Bonavides-Martinez,C., Miranda-Rios,J., Huerta,A.M., Mendoza-Vargas,A., Collado-Torres,L., Taboada,B., Vega-Alvarado,L., Olvera,M., Olvera,L., Grande,R., Morett,E., Collado-Vides,J.. RegulonDB version 7.0: transcriptional regulation of Escherichia coli K-12 integrated within genetic sensory response units (Gensor Units). Nucleic Acids Research, 39 (Suppl 1), D98-D105.
Open Access Artículo
127 - Massimelli,M.J., Sanchez,D.G., Buchieri,M.V., Olvera,L., Beassoni,P.R., Schweizer,H.P., Morett,E., Lisa,A.T.. Choline catabolism, sigma(54) factor and NtrC are required for the full expression of the Pseudomonas aeruginosa phosphorylcholine phosphatase gene. Microbiological Research, 166 (5), 380-390.
Open Access Revisión
128 - Collado-Vides,J., Salgado,H., Morett,E., Gama-Castro,S., Jimenez-Jacinto,V., Martinez-Flores,I., Medina-Rivera,A., Muniz-Rascado,L., Peralta-Gil,M., Santos-Zavaleta,A.. Bioinformatics resources for the study of gene regulation in bacteria. Journal of Bacteriology, 191 (1), 23-31.
Open Access Artículo
Open Access Artículo
Internacional
131 - Tapia,J.J., Morett,E., Vallejo,E.E.. A clustering genetic algorithm for genomic data mining. Foundations of Computational Intelligence . Studies in Computational Intelligence, 249-275, 4, Berlin, Heidelberg: Springer.
Memoria in extenso
132 - Tapia,J.J., Vallejo,E.E., Morett,E.. MOCEA: A multi-objective clustering evolutionary algorithm for inferring protein-protein functional interactions. Proceedings of the 11th Annual Genetic and Evolutionary Computation Conference, GECCO-2009. 1793-1794.
Open Access Artículo
133 - Gama-Castro,S., Jimenez-Jacinto,V., Peralta-Gil,M., Santos-Zavaleta,A., Penaloza-Spinola,M.I., Contreras-Moreira,B., Segura-Salazar,J., Muniz-Rascado,L., Martinez-Flores,I., Salgado,H., Bonavides-Martinez,C., Abreu-Goodger,C., Rodriguez-Penagos,C., Miranda-Rios,J., Morett,E., Merino,E., Huerta,A.M., Trevino-Quintanilla,L., Collado-Vides,J.. RegulonDB (version 6.0): gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation. Nucleic Acids Research, 36 (Database issue), D120-D124.
Artículo
Open Access Artículo
135 - Watanabe,R.L., Morett,E., Vallejo,E.E.. Inferring modules of functionally interacting proteins using the Bond Energy Algorithm. BMC Bioinformatics, 9 (1), 285.
Memoria in extenso
136 - Molina-Lozano,H., Vallejo-Clemente,E.E., Morett-Sanchez,J.E.. DNA sequence analysis using fuzzy grammars. IEEE International Conference on Fuzzy Systems. 1915-1921.
Open Access Artículo
137 - Dago,A.E., Wigneshweraraj,S.R., Buck,M., Morett,E.. A role for the conserved GAFTGA motif of AAA transcriptional activators in sensing promoter DNA conformation. Journal of Biological Chemistry, 282 (2), 1087-1097.
Artículo
138 - Hernandez-Urzua,E., Zamorano-Sanchez,D.S., Ponce-Coria,J., Morett,E., Grogan,S., Poole,R.K., Membrillo-Hernandez,J.. Multiple regulators of the Flavohaemoglobin (hmp) gene of Salmonella enterica serovar Typhimurium include RamA, a transcriptional regulator conferring the multidrug resistance phenotype. Archives of Microbiology, 187 (1), 67-77.
Memoria in extenso
139 - Martínez,M., Vallejo,E.E., Morett,E.. Ancestral DNA sequence reconstruction using recursive genetic algorithms. Lecture Notes in Computer Science, vol 4828 cap 4. 390-400.
Artículo; Actas Paper
140 - Aguilar-Diaz,H., Bobes,R.J., Carrero,J.C., Camacho-Carranza,R., Cervantes,C., Cevallos,M.A., Davila,G., Rodriguez-Dorantes,M., Escobedo,G., Fernandez,J.L., Fragoso,G., Gaytan,P., Garciarrubio,A., Gonzalez,V.M., Gonzalez,L., Jose,M.V., Jimenez,L., Laclette,J.P., Landa,A., Larralde,C., Morales-Montor,J., Morett,E., Ostoa-Saloma,P., Sciutto,E., Santamaria,R.I., Soberon,X., de la Torre P., Valdes,V., Yanez,J.. The genome project of Taenia solium. Parasitology International, 55 (Suppl), S127-S130.
Open Access Artículo
141 - Avonce,N., Mendoza-Vargas,A., Morett,E., Iturriaga,G.. Insights on the evolution of trehalose biosynthesis. BMC Evolutionary Biology, 6 (1), 109.
Open Access Artículo
142 - Huerta,A.M., Francino,M.P., Morett,E., Collado-Vides,J.. Selection for Unequal Densities of sigma(70) Promoter-Like Signals in Different Regions of Large Bacterial Genomes. PLoS Genetics, 2 (11), e185.
Memoria in extenso
143 - Fernandez,J.C., Vallejo,E.E., Morett,E.. Fuzzy C-means for inferring functional coupling of proteins from their phylogenetic profiles. Computational Intelligence and Bioinformatics and Computational Biology, 2006. CIBCB '06. 2006 IEEE Symposium on. 1-8.
Memoria in extenso
144 - Watanabe,R., Vallejo,E.E., Morett,E.. Inferring functional coupling of proteins using the Evolutionary Bond Energy Algorithm. Proceedings of the 2006 IEEE Symposium on Computational Intelligence in Bioinformatics and Computational Biology, CIBCB'06. 400-405.
Artículo
145 - Gaytan,P., Yanez,J., Grande,R., Morett,E., Soberon,X.. Improving random mutagenesis by purification of the oligonucleotide variants. Combinatorial Chemistry & High Throughput Screening, 8 (6), 537-544.
Artículo
149 - Morett,E., Korbel,J.O., Rajan,E., Saab-Rincon,G., Olvera,L., Olvera,M., Schmidt,S., Snel,B., Bork,P.. Systematic discovery of analogous enzymes in thiamin biosynthesis. Nature Biotechnology, 21 (7), 790-795.
Internacional
150 - Morett,E., Saab-Rincon,G., Merino,E., Bork,P., Rajan,E., Olvera,L., Olvera,M.. High rate of gene displacement in vitamin biosynthesis pathways. Bioinformatics and genomes: current perspectives. 69-79, Norfolk,U.K..
Open Access Artículo; Actas
151 - Morett,E., Korbel,J.O., Rajan,E., Saab-Rincon,G., Olvera,L., Olvera,M., Schmidt,S., Snel,B., Bork,P.. Discovery of Analogous Enzymes in Thiamin Biosynthesis by Anticorrelation. Genome Informatics, 13, 365-366.
Artículo
152 - Chaney,M., Grande,R., Wigneshweraraj,S.R., Cannon,W., Casaz,P., Gallegos,M.T., Schumacher,J., Jones,S., Elderkin,S., Dago,A.E., Morett,E., Buck,M.. Binding of transcriptional activators to sigma 54 in the presence of the transition state analog ADP-aluminum fluoride: insights into activator mechanochemical action. Genes and Development, 15 (17), 2282-2294.
Nacional
153 - Morett,E.. Genetic regulation of nitrogen fixation: from ammonia ssimilation to protein evolution. Nitrogen Fixation Research Center XX Anniversary. 180-183.
Artículo
154 - Juarez,K., Flores,H., Davila,S., Olvera,L., Gonzalez,V., Morett,E.. Reciprocal domain evolution within a transactivator in a restricted sequence space. Proceedings of the National Academy of Sciences of the United States of America, 97 (7), 3314-3318.
Open Access Revisión
Artículo
Artículo
157 - Morett,E., Bork,P.. A novel transactivation domain in parkin. Trends in Biochemical Sciences, 24 (6), 229-231.
Open Access Artículo
Open Access Artículo
Open Access Artículo
Open Access Artículo
168 - Cannon,W.V., Kreutzer,R., Kent,H.M., Morett,E., Buck,M.. Activation of the Klebsiella pneumoniae nifU promoter: identification of multiple and overlapping upstream NifA binding sites. Nucleic Acids Research, 18 (7), 1693-1701. *
Artículo
169 - Morett,E., Kreutzer,R., Cannon,W., Buck,M.. The influence of the Klebsiella pneumoniae regulatory gene nifL upon the transcriptional activator protein NifA. Molecular Microbiology, 4 (8), 1253-1258. *
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Open Access Artículo
173 - Morett,E., Buck,M.. NifA-dependent in vivo protection demonstrates that the upstream activator sequence of nif promoters is a protein binding site. Proceedings of the National Academy of Sciences of the United States of America, 85 (24), 9401-9405. *
Note
174 - Romero,D., Singleton,P.W., Segovia,L., Morett,E., Benbohlool,B., Palacios,R., Davila,G.. Effect of Naturally Occurring nif Reiterations on Symbiotic Effectiveness in Rhizobium phaseoli. Applied and Environmental Microbiology, 54 (3), 848-850. *
Open Access Note
176 - Calderon,J., Morett,E., Mora,J.. Omega-amidase pathway in the degradation of glutamine in Neurospora crassa. Journal of Bacteriology, 161 (2), 807-809. *
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