Dr. Ignacio Lopez Gonzalez
Investigador
Farmacología de canales iónicos
Fisiología molecular del espermatozoide
Número de registros: 9
- Activos
- Vencidos
- El atp como inductor del cambio de volumen de la cabeza del espermatozoide humano, una etapa previa a la reacción acrosomal, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2024 - 2025
- The elasticity of male fertility by means of phonon microscopy, 2024 - 2025
- Revaluación del papel fisiológico del atp y de los receptores purinérgicos del espermatozoide humano en los eventos tempranos de la reacción acrosomal, 2022 - 2025
- El atp en la fisiología de la reproducción, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2022 - 2024
- El uso de la microscopía de conductancia iónica para evaluar la participación de los receptores purinérgicos del espermatozoide humano en la reacción acrosomal inducida por atp, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2018 - 2021
- Estudio de los canales iónicos del espermatozoide después de que ocurre la reacción acrosomal, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2014 - 2017
- Inhibición de la expresion de los canales de k+ shal, shab y shaw en los cuerpos fungiformes de drosophila melanogaster, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2010 - 2012
- Evaluación del papel de las corrientes de k+ dependientes de voltaje en los fenómenos de plasticidad sináptica involucrados en el establecimiento y la consolidación de la memoria asociativa en drosophila melanogaster, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2008 - 2011
- Inhibición de la expresión de los canales de k+ shal, shab y shaw en los cuerpos fungiformes de drosophila melanogaster, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2007 - 2009
Nivel B del PRIDE
Nivel I del SNII
Nivel I del SNII
Doctorado, en Ciencias Bioquímicas IBt-UNAM (2002)
- Activos
- Graduados
1 - Sanchez Carranza, Oscar (2015). Estudio farmacologico del canal de K+ SLO3 de humano para evaluar su contribucion en la hiperpolarizacion asociada a la capacitacion.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Lopez Gonzalez, Ignacio
2 - Sanchez Carranza, Oscar (2013). Desarrollo de herramientas moleculares para el estudio del canal de k+ slo3 especifico del espermatozoide de mamiferos .
Facultad de Ciencias,
Licenciatura en Biologia,
UNAM.
*
Asesor: Lopez Gonzalez, Ignacio
3 - Cortes Mendoza, Cesar Javier (2011). Establecimiento de la línea de moscas transgenicas UAS-Shall371D para evaluar el papel de los canales shal residentes del cuerpo fungiforme.
Instituto de Biotecnologia,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Lopez Gonzalez, Ignacio
Total de publicaciones: 34
- Tipo
- Fecha
Artículo
4 - Arcos-Hernandez,C., Suarez-Delgado,E., Islas,L.D., Romero,F., Lopez-Gonzalez,I., Ai,H.W., Nishigaki,T. (2023). How to study a highly toxic protein to bacteria: A case of voltage sensor domain of mouse sperm-specific sodium/proton exchanger.
Protein Expression and Purification,
201,
106172.
Artículo
5 - Lopez-Gonzalez,I., Sanchez-Cardenas,C., de la Vega-Beltran,J.L., Alvarado-Quevedo,B., Ocelotl-Oviedo,J.P., Gonzalez-Cota,A.L., Aldana,A., Orta,G., Darszon,A. (2023). ATP increases head volume in capacitated human sperm via a purinergic channel.
Biochemical and Biophysical Research Communications,
671,
318-326.
Revisión
6 - Darszon,A., Nishigaki,T., Lopez-Gonzalez,I., Visconti,P.E., Trevino,C.L. (2020). Differences and Similarities: The Richness of Comparative Sperm Physiology.
Physiology (Bethesda.),
35 (3),
196-208.
Artículo
7 - Garza-Lopez,E., Aldana,A., Darszon,A., Nishigaki,T., Lopez-Gonzalez,I. (2020). CaV3.1 channel pore pseudo-symmetry revealed by selectivity filter mutations in its domains I/II.
Cell Calcium,
89,
102214.
Artículo
8 - Bondarenko,O., Corzo,G., Santana,F.L., del Rio-Portilla,F., Darszon,A., Lopez-Gonzalez,I. (2019). Non-enzymatically oxidized arachidonic acid regulates T-type Ca(2+) currents in mouse spermatogenic cells.
FEBS Letters,
593 (14),
1735-1750.
Artículo
9 - Santana-Calvo, C., Romero, F., Lopez-Gonzalez, I., Nishigaki, T. (2018). Robust evaluation of intermolecular FRET using a large Stokes shift fluorophore as a donor.
Biotechniques,
65 (4),
211-218.
Artículo
10 - Garza-Lopez,E., Chavez,J.C., Santana-Calvo,C., Lopez-Gonzalez,I., Nishigaki,T. (2016). Cd2+ sensitivity and permeability of a low voltage-activated Ca2+ channel with CatSper-like selectivity filter.
Cell Calcium,
60 (1),
41-50.
Artículo
11 - Lopez-Gonzalez,I., Trevino,C.L., Darszon,A. (2016). Regulation of Spermatogenic Cell T-Type Ca Currents by Zn : Implications in Male Reproductive Physiology.
Journal of Cellular Physiology,
231 (3),
659-667.
Artículo
12 - Garza-Lopez,E., Sanchez-Carranza,O., Nishigaki,T., Lopez-Gonzalez,I. (2015). Pharmacological identification of endogenous slo1 channel-á1 subunit complexes in CHO cells using three àKTx1 subfamily toxins.
International Journal of Pharmacy & Therapeutics,
6 (1),
11-24.
Artículo
13 - Sanchez-Carranza,O., Torres-Rodriguez,P., Darszon,A., Trevino,C.L., Lopez-Gonzalez,I. (2015). Pharmacology of hSlo3 channels and their contribution in the capacitation-associated hyperpolarization of human sperm.
Biochemical and Biophysical Research Communications,
466 (3),
554-559.
Revisión
14 - Lopez-Gonzalez,I., Torres-Rodriguez,P., Sanchez-Carranza,O., Solis-Lopez,A., Santi,C.M., Darszon,A., Trevino,C.L. (2014). Membrane Hyperpolarization during Human Sperm Capacitation.
Molecular Human Reproduction,
20 (7),
619-629.
Revisión
15 - Darszon,A., Sanchez-Cardenas,C., Orta,G., Sanchez-Tusie,A.A., Beltran,C., Lopez-Gonzalez,I., Granados-Gonzalez,G., Trevino,C.L. (2012). Are TRP channels involved in sperm development and function?.
Cell and Tissue Research,
349 (3),
749-764.
Artículo
16 - Hernandez-Vargas,R., Fonseca-Ornelas,L., Lopez-Gonzalez,I., Riesgo-Escovar,J., Zurita,M., Reynaud,E. (2011). Synphilin suppresses a-synuclein neurotoxicity in a Parkinson's disease Drosophila model.
Genesis,
49 (5),
392-402.
Artículo
17 - Castillo,E., Lopez-Gonzalez,I., De Regil-Hernandez,R., Reyes-Duarte,D., Sanchez-Herrera,D., Lopez-Munguia,A., Darszon,A. (2007). Enzymatic synthesis of capsaicin analogs and their effect on the T-type Ca(2+) channels.
Biochemical and Biophysical Research Communications,
356 (2),
424-430.
Artículo
18 - Hernandez-Gonzalez,E.O., Sosnik,J., Edwards,J., Acevedo,J.J., Mendoza-Lujambio,I., Lopez-Gonzalez,I., Demarco,I., Wertheimer,E., Darszon,A., Visconti,P.E. (2006). Sodium and epithelial sodium channels participate in the regulation of the capacitation-associated hyperpolarization in mouse sperm.
Journal of Biological Chemistry,
281 (9),
5623-5633.
Artículo
19 - Rodriguez-Valentin,R., Lopez-Gonzalez,I., Jorquera,R., Labarca,P., Zurita,M., Reynaud,E. (2006). Oviduct contraction in Drosophila is modulated by a neural network that is both, octopaminergic and glutamatergic.
Journal of Cellular Physiology,
209 (1),
183-198.
Artículo
20 - Sandoz,G., Lopez-Gonzalez,I., Stamboulian,S., Weiss,N., Arnoult,C., De Waard,M. (2004). Repositioning of charged I-II loop amino acid residues within the electric field by beta subunit as a novel working hypothesis for the control of fast P/Q calcium channel inactivation.
European Journal of Neuroscience,
19 (7),
1759-1772.
*
Artículo
21 - Sandoz,G., Lopez-Gonzalez,I., Grunwald,D., Bichet,D., Altafaj,X., Weiss,N., Ronjat,M., Dupuis,A., De Waard,M. (2004). Cav{beta}-subunit displacement is a key step to induce the reluctant state of P/Q calcium channels by direct G protein regulation.
Proceedings of the National Academy of Sciences of the United States of America,
101 (16),
6267-6272.
*
Artículo
22 - Trevino,C.L., Felix,R., Castellano,L.E., Gutierrez,C., Rodriguez,D., Pacheco,J., Lopez-Gonzalez,I., Gomora,J.C., Tsutsumi,V., Hernandez-Cruz,A., Fiordelisio,T., Scaling,A.L., Darszon,A. (2004). Expression and differential cell distribution of low-threshold Ca(2+) channels in mammalian male germ cells and sperm.
FEBS Letters,
563 (1-3),
87-92.
Artículo
23 - Lopez-Gonzalez,I., Olamendi-Portugal,T., de la Vega-Beltran,J.L., van der Walt,J., Dyason,K., Possani,L.D., Felix,R., Darszon,A. (2003). Scorpion toxins that block T-type Ca(2+) channels in spermatogenic cells inhibit the sperm acrosome reaction.
Biochemical and Biophysical Research Communications,
300 (2),
408-414.
Artículo
24 - M'Barek,S., Lopez-Gonzalez,I., Andreotti,N., di Luccio,E., Visan,V., Grissmer,S., Judge,S., El Ayeb,M., Darbon,H., Rochat,H., Sampieri,F., Beraud,E., Fajloun,Z., De Waard,M., Sabatier,J.M. (2003). A maurotoxin with constrained standard disulfide bridging: innovative strategy of chemical synthesis, pharmacology, and docking on K+ channels.
Journal of Biological Chemistry,
278 (33),
31095-31104.
*
Artículo
25 - Olamendi-Portugal,T., Garcia,B.I., Lopez-Gonzalez,I., van der Walt,J., Dyason,K., Ulens,C., Tytgat,J., Felix,R., Darszon,A., Possani,L.D. (2002). Two new scorpion toxins that target voltage-gated Ca(2+) and Na(+) channels.
Biochemical and Biophysical Research Communications,
299 (4),
562-568.
Artículo
26 - Lopez-Gonzalez,I., de la Vega-Beltran,J.L., Santi,C.M., Florman,H.M., Felix,R., Darszon,A. (2001). Calmodulin antagonists inhibit t-type ca(2+) currents in mouse spermatogenic cells and the zona pellucida-induced sperm acrosome reaction.
Developmental Biology,
236 (1),
210-219.
Artículo
27 - Espinosa,F., Lopez-Gonzalez,I., Munoz-Garay,C., Felix,R., de la Vega-Beltran,J.L., Kopf,G.S., Visconti,P.E., Darszon,A. (2000). Dual regulation of the T-type Ca(2+) current by serum albumin and beta-estradiol in mammalian spermatogenic cells.
FEBS Letters,
475 (3),
251-256.
Artículo
28 - Espinosa,F., Lopez-Gonzalez,I., Serrano,C.J., Gasque,G., de la Vega-Beltran,J.L., Trevino,C.L., Darszon,A. (1999). Anion channel blockers differentially affect T-type Ca(2+) currents of mouse spermatogenic cells, alpha1E currents expressed in Xenopus oocytes and the sperm acrosome reaction.
Developmental Genetics,
25 (2),
103-114.
Artículo
29 - Darszon,A., Espinoza,F., Santi,C., Lievano,A., Lopez,I., de la Vega-Beltran,J.L., Delgado,R., Labarca,P., Hernandez,A. (1998). Ca 2+ and Cl - channels in sperm physiology.
Zygote,
6 (1 SUPPL.),
S22-S23.
Artículo
30 - Espinosa,F., de la Vega-Beltran,J.L., Lopez-Gonzalez,I., Delgado,R., Labarca,P., Darszon,A. (1998). Mouse sperm patch-clamp recordings reveal single Cl- channels sensitive to niflumic acid, a blocker of the sperm acrosome reaction.
FEBS Letters,
426 (1),
47-51.
Capítulo internacional
31 - Darszon, A., Ferreira, J.J., López-González, I., Orta, G., Treviño, C.L., Santi, C.M. (2022). Voltage-Dependent Calcium Channels (CaVs) and CatSper in Spermatogenic and Sperm Cells, in Voltage Gated Calcium Channels. Voltage-Gated Calcium Channels.
Cham: Springer.
Internacional
32 - Reyes, J. G., Sanchez-Cardenas, C., Acevedo-Castillo, W., Leyton, P., Lopez-Gonzalez, I., Felix, R., Gandini, M. A., Trevino, M. B., Trevino, C. L. (2014). Maitotoxin: An Enigmatic Toxic Molecule with Useful Applications in the Biomedical Sciences. Seafood and Freshwater Toxins. Pharmacology, Physiology, and Detection.
677-694,
Boca Raton,
3.
Internacional
33 - Felix,R., Lopez-Gonzalez,I., Munoz-Garay,C., Darszon,A. (2004). Ion channels and sperm function. Molecular Insights into Ion Channel Biology in Health and Disease.
Advances in Molecular and Cell Biology, 32,
407-431.
Nacional
34 - Darszon,A., Lopez,I, Trevino,C.L. (2003). Diálogo entre el espermatozoide y el óvulo. Fronteras de la Biología en los Inicios del Siglo XXI, Biología Celular, Genética Molecular y Biotecnología, Módulo II.
33-55,
Mexico,D.F..
Preprint
35 - Bondarenko,O., Corzo,G., Santana,F.L., del Rio-Portilla,F., Darszon,A., Lopez-Gonzalez,I. (2019). Non-enzymatically oxidized arachidonic acid regulates mouse spermatogenic cell T-type Ca 2+ currents.
bioRxiv,
Posted March 23, 2019.,
586297.
Preprint
36 - Garza-Lopez,E., Aldana,A., Darszon,A., Nishigaki,T., Lopez-Gonzalez,I. (2019). CaV3.1 channel pore pseudo-symmetry revealed by selectivity filter mutations in their domains I/II.
bioRxiv,
Posted May 02, 2019,
626069.
37 - Lopez Gonzalez, Ignacio (2002). Modulacion y farmacologia de la corriente de Ca2+ tipo T en celulas espermatogenicas de raton .
Instituto de Biotecnologia,
Doctor en Ciencias Bioquimicas,
UNAM.
Asesor: Darszon Israel, Alberto
Artículo
38 - Arcos-Hernandez,C., Suarez-Delgado,E., Islas,L.D., Romero,F., Lopez-Gonzalez,I., Ai,H.W., Nishigaki,T.. How to study a highly toxic protein to bacteria: A case of voltage sensor domain of mouse sperm-specific sodium/proton exchanger.
Protein Expression and Purification,
201,
106172.
Artículo
39 - Lopez-Gonzalez,I., Sanchez-Cardenas,C., de la Vega-Beltran,J.L., Alvarado-Quevedo,B., Ocelotl-Oviedo,J.P., Gonzalez-Cota,A.L., Aldana,A., Orta,G., Darszon,A.. ATP increases head volume in capacitated human sperm via a purinergic channel.
Biochemical and Biophysical Research Communications,
671,
318-326.
Capítulo internacional
40 - Darszon, A., Ferreira, J.J., López-González, I., Orta, G., Treviño, C.L., Santi, C.M.. Voltage-Dependent Calcium Channels (CaVs) and CatSper in Spermatogenic and Sperm Cells, in Voltage Gated Calcium Channels. Voltage-Gated Calcium Channels.
Cham: Springer.
Revisión
41 - Darszon,A., Nishigaki,T., Lopez-Gonzalez,I., Visconti,P.E., Trevino,C.L.. Differences and Similarities: The Richness of Comparative Sperm Physiology.
Physiology (Bethesda.),
35 (3),
196-208.
Artículo
42 - Garza-Lopez,E., Aldana,A., Darszon,A., Nishigaki,T., Lopez-Gonzalez,I.. CaV3.1 channel pore pseudo-symmetry revealed by selectivity filter mutations in its domains I/II.
Cell Calcium,
89,
102214.
Artículo
43 - Bondarenko,O., Corzo,G., Santana,F.L., del Rio-Portilla,F., Darszon,A., Lopez-Gonzalez,I.. Non-enzymatically oxidized arachidonic acid regulates T-type Ca(2+) currents in mouse spermatogenic cells.
FEBS Letters,
593 (14),
1735-1750.
Preprint
44 - Bondarenko,O., Corzo,G., Santana,F.L., del Rio-Portilla,F., Darszon,A., Lopez-Gonzalez,I.. Non-enzymatically oxidized arachidonic acid regulates mouse spermatogenic cell T-type Ca 2+ currents.
bioRxiv,
Posted March 23, 2019.,
586297.
Preprint
45 - Garza-Lopez,E., Aldana,A., Darszon,A., Nishigaki,T., Lopez-Gonzalez,I.. CaV3.1 channel pore pseudo-symmetry revealed by selectivity filter mutations in their domains I/II.
bioRxiv,
Posted May 02, 2019,
626069.
Artículo
46 - Santana-Calvo, C., Romero, F., Lopez-Gonzalez, I., Nishigaki, T.. Robust evaluation of intermolecular FRET using a large Stokes shift fluorophore as a donor.
Biotechniques,
65 (4),
211-218.
Artículo
47 - Garza-Lopez,E., Chavez,J.C., Santana-Calvo,C., Lopez-Gonzalez,I., Nishigaki,T.. Cd2+ sensitivity and permeability of a low voltage-activated Ca2+ channel with CatSper-like selectivity filter.
Cell Calcium,
60 (1),
41-50.
Artículo
48 - Lopez-Gonzalez,I., Trevino,C.L., Darszon,A.. Regulation of Spermatogenic Cell T-Type Ca Currents by Zn : Implications in Male Reproductive Physiology.
Journal of Cellular Physiology,
231 (3),
659-667.
Artículo
49 - Garza-Lopez,E., Sanchez-Carranza,O., Nishigaki,T., Lopez-Gonzalez,I.. Pharmacological identification of endogenous slo1 channel-á1 subunit complexes in CHO cells using three àKTx1 subfamily toxins.
International Journal of Pharmacy & Therapeutics,
6 (1),
11-24.
Artículo
50 - Sanchez-Carranza,O., Torres-Rodriguez,P., Darszon,A., Trevino,C.L., Lopez-Gonzalez,I.. Pharmacology of hSlo3 channels and their contribution in the capacitation-associated hyperpolarization of human sperm.
Biochemical and Biophysical Research Communications,
466 (3),
554-559.
Revisión
51 - Lopez-Gonzalez,I., Torres-Rodriguez,P., Sanchez-Carranza,O., Solis-Lopez,A., Santi,C.M., Darszon,A., Trevino,C.L.. Membrane Hyperpolarization during Human Sperm Capacitation.
Molecular Human Reproduction,
20 (7),
619-629.
Internacional
52 - Reyes, J. G., Sanchez-Cardenas, C., Acevedo-Castillo, W., Leyton, P., Lopez-Gonzalez, I., Felix, R., Gandini, M. A., Trevino, M. B., Trevino, C. L.. Maitotoxin: An Enigmatic Toxic Molecule with Useful Applications in the Biomedical Sciences. Seafood and Freshwater Toxins. Pharmacology, Physiology, and Detection.
677-694,
Boca Raton,
3.
Revisión
53 - Darszon,A., Sanchez-Cardenas,C., Orta,G., Sanchez-Tusie,A.A., Beltran,C., Lopez-Gonzalez,I., Granados-Gonzalez,G., Trevino,C.L.. Are TRP channels involved in sperm development and function?.
Cell and Tissue Research,
349 (3),
749-764.
Artículo
54 - Hernandez-Vargas,R., Fonseca-Ornelas,L., Lopez-Gonzalez,I., Riesgo-Escovar,J., Zurita,M., Reynaud,E.. Synphilin suppresses a-synuclein neurotoxicity in a Parkinson's disease Drosophila model.
Genesis,
49 (5),
392-402.
Artículo
55 - Castillo,E., Lopez-Gonzalez,I., De Regil-Hernandez,R., Reyes-Duarte,D., Sanchez-Herrera,D., Lopez-Munguia,A., Darszon,A.. Enzymatic synthesis of capsaicin analogs and their effect on the T-type Ca(2+) channels.
Biochemical and Biophysical Research Communications,
356 (2),
424-430.
Artículo
56 - Hernandez-Gonzalez,E.O., Sosnik,J., Edwards,J., Acevedo,J.J., Mendoza-Lujambio,I., Lopez-Gonzalez,I., Demarco,I., Wertheimer,E., Darszon,A., Visconti,P.E.. Sodium and epithelial sodium channels participate in the regulation of the capacitation-associated hyperpolarization in mouse sperm.
Journal of Biological Chemistry,
281 (9),
5623-5633.
Artículo
57 - Rodriguez-Valentin,R., Lopez-Gonzalez,I., Jorquera,R., Labarca,P., Zurita,M., Reynaud,E.. Oviduct contraction in Drosophila is modulated by a neural network that is both, octopaminergic and glutamatergic.
Journal of Cellular Physiology,
209 (1),
183-198.
Artículo
58 - Sandoz,G., Lopez-Gonzalez,I., Stamboulian,S., Weiss,N., Arnoult,C., De Waard,M.. Repositioning of charged I-II loop amino acid residues within the electric field by beta subunit as a novel working hypothesis for the control of fast P/Q calcium channel inactivation.
European Journal of Neuroscience,
19 (7),
1759-1772.
*
Artículo
59 - Sandoz,G., Lopez-Gonzalez,I., Grunwald,D., Bichet,D., Altafaj,X., Weiss,N., Ronjat,M., Dupuis,A., De Waard,M.. Cav{beta}-subunit displacement is a key step to induce the reluctant state of P/Q calcium channels by direct G protein regulation.
Proceedings of the National Academy of Sciences of the United States of America,
101 (16),
6267-6272.
*
Artículo
60 - Trevino,C.L., Felix,R., Castellano,L.E., Gutierrez,C., Rodriguez,D., Pacheco,J., Lopez-Gonzalez,I., Gomora,J.C., Tsutsumi,V., Hernandez-Cruz,A., Fiordelisio,T., Scaling,A.L., Darszon,A.. Expression and differential cell distribution of low-threshold Ca(2+) channels in mammalian male germ cells and sperm.
FEBS Letters,
563 (1-3),
87-92.
Internacional
61 - Felix,R., Lopez-Gonzalez,I., Munoz-Garay,C., Darszon,A.. Ion channels and sperm function. Molecular Insights into Ion Channel Biology in Health and Disease.
Advances in Molecular and Cell Biology, 32,
407-431.
Artículo
62 - Lopez-Gonzalez,I., Olamendi-Portugal,T., de la Vega-Beltran,J.L., van der Walt,J., Dyason,K., Possani,L.D., Felix,R., Darszon,A.. Scorpion toxins that block T-type Ca(2+) channels in spermatogenic cells inhibit the sperm acrosome reaction.
Biochemical and Biophysical Research Communications,
300 (2),
408-414.
Artículo
63 - M'Barek,S., Lopez-Gonzalez,I., Andreotti,N., di Luccio,E., Visan,V., Grissmer,S., Judge,S., El Ayeb,M., Darbon,H., Rochat,H., Sampieri,F., Beraud,E., Fajloun,Z., De Waard,M., Sabatier,J.M.. A maurotoxin with constrained standard disulfide bridging: innovative strategy of chemical synthesis, pharmacology, and docking on K+ channels.
Journal of Biological Chemistry,
278 (33),
31095-31104.
*
Nacional
64 - Darszon,A., Lopez,I, Trevino,C.L.. Diálogo entre el espermatozoide y el óvulo. Fronteras de la Biología en los Inicios del Siglo XXI, Biología Celular, Genética Molecular y Biotecnología, Módulo II.
33-55,
Mexico,D.F..
Artículo
65 - Olamendi-Portugal,T., Garcia,B.I., Lopez-Gonzalez,I., van der Walt,J., Dyason,K., Ulens,C., Tytgat,J., Felix,R., Darszon,A., Possani,L.D.. Two new scorpion toxins that target voltage-gated Ca(2+) and Na(+) channels.
Biochemical and Biophysical Research Communications,
299 (4),
562-568.
66 - Lopez Gonzalez, Ignacio. Modulacion y farmacologia de la corriente de Ca2+ tipo T en celulas espermatogenicas de raton .
Instituto de Biotecnologia,
Doctor en Ciencias Bioquimicas,
UNAM.
Asesor: Darszon Israel, Alberto
Artículo
67 - Lopez-Gonzalez,I., de la Vega-Beltran,J.L., Santi,C.M., Florman,H.M., Felix,R., Darszon,A.. Calmodulin antagonists inhibit t-type ca(2+) currents in mouse spermatogenic cells and the zona pellucida-induced sperm acrosome reaction.
Developmental Biology,
236 (1),
210-219.
Artículo
68 - Espinosa,F., Lopez-Gonzalez,I., Munoz-Garay,C., Felix,R., de la Vega-Beltran,J.L., Kopf,G.S., Visconti,P.E., Darszon,A.. Dual regulation of the T-type Ca(2+) current by serum albumin and beta-estradiol in mammalian spermatogenic cells.
FEBS Letters,
475 (3),
251-256.
Artículo
69 - Espinosa,F., Lopez-Gonzalez,I., Serrano,C.J., Gasque,G., de la Vega-Beltran,J.L., Trevino,C.L., Darszon,A.. Anion channel blockers differentially affect T-type Ca(2+) currents of mouse spermatogenic cells, alpha1E currents expressed in Xenopus oocytes and the sperm acrosome reaction.
Developmental Genetics,
25 (2),
103-114.
Artículo
70 - Darszon,A., Espinoza,F., Santi,C., Lievano,A., Lopez,I., de la Vega-Beltran,J.L., Delgado,R., Labarca,P., Hernandez,A.. Ca 2+ and Cl - channels in sperm physiology.
Zygote,
6 (1 SUPPL.),
S22-S23.
Artículo
71 - Espinosa,F., de la Vega-Beltran,J.L., Lopez-Gonzalez,I., Delgado,R., Labarca,P., Darszon,A.. Mouse sperm patch-clamp recordings reveal single Cl- channels sensitive to niflumic acid, a blocker of the sperm acrosome reaction.
FEBS Letters,
426 (1),
47-51.