Dr. Alejandro Alagón Cano
Investigador Emérito
Alejandro Alagón Cano (Ciudad de México, 1954) es un médico, investigador, catedrático y académico mexicano. Se ha especializado en las áreas de biotecnología de los anticuerpos y toxinología (véase toxina), en la investigación para el mejoramiento de antivenenos y el desarrollo de nuevos antivenenos. Recibió el Premio Nacional de Ciencias y Artes en el 2005.
Biología Molecular y Bioquímica de venenos de animales ponzoñosos
Bioprocesos con aplicaciones biotecnológicas y para la generación de medicamentos biotecnológicos
Antivenenos para animales ponzoñosos con una pureza y refinamiento que reducen de forma importante las reacciones adversas típicas de estas terapias de emergencia.
Número de registros: 24
- Activos
- Vencidos
- Desarrollo de un antiveneno recombinante a partir de anticuerpos monoclonales para tratar pacientes envenenados por araña viuda negra (latrodectus sp.), DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2025 - 2027
- Consecuencias funcionales de la variación genómica, transcriptómica y proteómica en el veneno de las serpientes de cascabel de cola negra y sus implicaciones en el tratamiento con antiveneno, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2020 - 2024
- Venenos y antivenenos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2020 - 2025
- Desarrollo de un sistema para evaluar la respuesta inmune temprana y convaleciente de pacientes infectados con sars-cov-2 y de inmunoterápicos para enfermos en estado crítico por covid-19, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1900
- Caracterización del veneno de tres serpientes de importancia médica en méxico: investigación básica y mejoramiento de antivenenos., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2021 - 2023
- 2º curso de animales venenosos en méxico, biología, investigación y clínica, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2018
- Investigación de venenos de serpientes para el mejoramiento de antivenenos, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2018 - 2021
- Automatización de llenado de bolsas de agua para ratas y ratones del bioterio del instituto de biotecnología-unam, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2015 - 2016
- Caracterización funcional del veneno de agkistrodon, así como la respuesta inmune en caballos contra los mismos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2014 - 2018
- Biotecnología de anticuerpos terapéuticos y diagnósticos, y toxinología aplicada, PRESUPUESTO UNAM, 2014 - 2020
- Identificación, análisis molecular y expresión heteróloga de neurotoxinas provenientes de elápidos y vipéridos para la generación de antivenenos de alta calidad, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2014 - 2017
- Análisis molecular y expresión heteróloga de neurotoxinas provenientes del veneno de coral (elápidos) para la generación de antivenenos de alta calidad, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2011 - 2013
- Phase 2 clinical trial of coralmyn for coral snake bite, UNIVERSITY OF ARIZONA, 2010 - 2016
- Desarrollo de un antiveneno de cobertura europea para el tratamiento de la intoxicación por mordedura de serpiente, FONDO DE COOPERACIÓN INTERNACIONAL EN CIENCIA Y TECNOLOGÍA UNIÓN EUROPEA - MÉXICO, 2009 - 2012
- Reconocimiento cruzado de venenos de coralillos de norteamerica, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2009
- Proyecto piloto referente al estudio del sistema linfático; a llevarse a cabo durante la segunda reunión de grupo de investigación sobre linfotoxicología, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2008 - 2009
- Toxoides recombinantes de arañas latrodectus y loxosceles., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2005
- Inhibición de funciones celulares en células humanas y de entamoeba histolytica mediante pna antisentido y antigene convalentemente modificados y usando glóbulos rojos acarreadores., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2002 - 2004
- Anticuerpos recombinantes humanos: obtención y evaluación funcional para el desarrollo de antivenenos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2000 - 2002
- Repertorios inteligentes de anticuerpos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2000 - 2002
- Caracterización de venenos y toxinas selectos de arañas mexicanas, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1999 - 2001
- Inhibición de funciones celulares en células humanas y en entamoeba histolytica mediante ácidos péptido nucleicos (pna) antisense y antigene., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1999 - 2002
- Enfoques moleculares para el estudio de la vía secretoria en entamoeba histolytica (3a. etapa), DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1997 - 2000
- Diseño de moléculas mejoradas de pna (ácido péptido-nucléico) para la expresión de genes específicos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1996 - 1998
Nivel D del PRIDE
Nivel Investigador Emérito del SNII
Nivel Investigador Emérito del SNII
Doctorado, en Ciencias, Instituto de Investigaciones Biomedicas, UNAM (1983)
Maestría, en Ciencias, Instituto de Investigaciones Biomedicas, UNAM (1980)
Licenciatura, Medico Cirujano, Fac. de Medicina, UNAM (1978)
Premio Luis Elizondo al sentido humano 2013, Sistema Tecnológico de Monterrey, 2013
Premio Nacional de Ciencias y Artes, Gobierno de la República, 2005
Premio UNAM 2004 Innovación Tecnológica, 2004
- Activos
- Graduados
-
Doctorado
-
Generación de antiveneno experimental neutralizante del veneno de abeja (Apis mellifera) y la reacción anafiláctica
-
Maestría
-
Audrey Michelle Rodríguez Solís
Cuantificación de veneno, familias proteicas y antiveneno en muestra de sangre de pacientes mordidos por vipéridos y elápidos mexicanos. -
Producción de un AcM neutralizante del veneno de L. mactans a partir de fragmentos recombinantes de la alfa-latrotoxina
-
Licenciatura
-
Caracterización de la alpha-latrotoxina de diferentes especies de arañas del género latrodectus del centro de México
1 - Yanez Mendoza, Manuel Francisco (2024). Caracterizacion funcional del veneno de la serpiente de coral mexicana Micrurus diastema .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
2 - Losoya Uribe, Luis Fernando (2024). Obtencion de un anticuerpo monoclonal neutralizante de la actividad esfingomielinasa D de Loxosceles boneti (Gertsch, 1958), como candidato en el desarrollo de un anticuerpo recombinante quimerico.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
3 - Corkidi Zajur, Tania (2023). Caracterizacion de la sphenotoxina de Ophryacus sphenophrys y su comparacion con la crotoxina clasica .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
4 - Aguayo Avalos, Oscar (2023). Evolucion de titulos de anticuerpos y potencias neutralizantes de sueros de caballo hiperinmunizados con mezclas complejas de venenos de viperidos y elapidos.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
5 - Colis Torres, Andrea (2021). Caracterizacion intraespecifica del veneno de Crotalus basiliscus (Cope, 1864) y su neutralizacion con un antiveneno mexicano.
Instituto de Biotecnología,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Alagon Cano, Alejandro
6 - Neri Castro, Edgar Enrique (2021). Farmacocinética en sangre y en linfa del veneno de la cascabel neotropical (Crotalus simus) en un modelo ovino.
Instituto de Investigaciones Biomedicas,
Doctorado en Ciencias Biomedicas,
UNAM.
*
Asesor: Alagon Cano, Alejandro
7 - Ponce Lopez, Jose Roberto (2020). Expresion heterologa de crotamina de Crotalus molossus nigrescens fusionada a esfingomielinasa D de loxosceles en Escherichia coli, para su utilizacion como posible inmunogeno.
Instituto de Biotecnologia,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Alagon Cano, Alejandro
8 - Benard Valle, Melisa (2020). Caracterizacion funcional y analisis de especificidad del veneno de la serpiente de coral Micrurus browni browni.
Instituto de Biotecnologia,
Doctorado en Bioquímicas,
UNAM.
Asesor: Alagon Cano, Alejandro
9 - Sarmiento Acuña, Karen Solanyi (2020). Comparación de la especificidad y capacidad neutralizante de dos antivenenos antiofídicos retados con veneno de serpiente del género Bothrops de Colombia.
Facultad de Medicina,
Maestría en Toxicología,
Universidad Nacional de Colombia.
*
Asesor: Castiblanco Rodríguez, Ana Lucía, Alagón Cano, Alejandro
10 - Corkidi Zajur, Tania (2020). Biodistribución de fragmentos de inmunoglobulinas tipo F(ab)? 2 en ratones, por análisis de imágenes.
Instituto de Investigacion en Ciencias Basicas y Aplicadas,
Licenciatura en Ciencias,
UAEM.
*
Asesor: Alagon Cano, Alejandro
11 - Castillo Perez, Irene Maria (2019). Producción de conjugados de crotamina y su evaluación como inmunógenos.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
12 - Borja Jiménez, Juan Miguel (2019). Variabilidad genética y caracterización bioquímica de las
metaloproteinasas y la toxina mojave de Crotalus scutulatus y Crotalus molossus del desierto
Chihuahuense.
Facultad de Ciencias Químicas,
Doctorado en Ciencias Biomédicas,
Universidad Juárez del Estado de Durango.
*
Asesor: Pérez Morales,Rebeca, Alagón Cano, Alejandro
13 - Barcenas Arriaga, Sergio (2018). Caracterizacion bioquimica y biologica del veneno de Bothrops asper (Garman, 1884) de Mexico .
Facultad de Ciencias,
Maestria en Ciencias Biologicas,
UNAM.
*
Asesor: Alagon Cano, Alejandro
14 - Roman Dominguez, Luis (2018). Aislamiento y caracterización de componentes con actividad edematizante presentes en el veneno de la serpiente Agkistrodon bilineatus.
Facultad de Medicina,
Maestria en Medicina Molecular,
UAEM.
*
Asesor: Petricevich, Vera Lucia, Alagon Cano, Alejandro
15 - Dzib Hau, Maria Fernanda (2016). Caracterizacion de los principales compuestos presentes en secreciones obtenidas de las glandulas parotidas de rhinella marina.
Instituto de Biotecnologia,
76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
16 - Vergara Bahena, Irene (2015). Caracterizacion del veneno de micrurus fulvius y biodistribucion in vivo de su principal toxina radiomarcada con 67galio.
Instituto de Biotecnologia,
94 paginas,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
17 - Hernandez Davila, Isabel Arely (2015). Crotoxina en el veneno de la serpiente de cascabel crotalus simus en Mexico : su relacion con la toxicidad y distribucion geografica .
Instituto de Biotecnologia,
76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
18 - Paniagua Meza, Dayanira (2014). Participacion del sistema linfatico en la absorcion y distribucion del veneno de micrurus fulvius.
Instituto de Biotecnologia,
74 paginas,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
19 - Mendoza Vera, Miguel Angel (2014). Expresion, purificacion y caracterizacion de la esfingomielinasa D recombinante de rhipicephalus microplus .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
20 - Guerrero Garzon, Jaime Felipe (2014). Clonacion, expresion y caracterizacion de alfaneurotoxinas de serpientes de coral mexicanas .
Instituto de Biotecnologia,
83 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
21 - Carbajal Saucedo, Alejandro (2014). Caracterizacion biologica, bioquimica e inmunoquimica del veneno de Micrurus laticollaris : bases para el desarrollo de un antiveneno de amplio espectro contra coralillos .
Instituto de Biotecnologia,
90 paginas,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
22 - Barron Castillo, Ulises (2014). Expresion de la alfaneurotoxina mlata1 de micrurus laticollaris en pichia pastoris y evaluacion de su uso como inmunogeno.
Instituto de Biotecnologia,
76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
23 - Rosa Hernandez, Guillermo de la (2011). Produccion de toxoides de serpientes africanas mediante radiacion gamma.
Instituto de Biotecnologia,
93 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
24 - Chavez Mendez, Ariana (2011). Participacion de los productos fosfoceramida y lisofosfatidato generados por la esfingomielinasa D del veneno de arana loxosceles, en la toxicidad de la enzima.
Instituto de Biotecnologia,
vi, 76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
25 - Calderon Corona, Arlene (2011). Caracterizacion de la respuesta inmune humoral en caballos contra el veneno de Micrurus tener.
Instituto de Biotecnologia,
78 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
26 - Benard Valle, Melisa (2011). Caracterizacion bioquimica del veneno de la serpiente de coral Micrurus tener.
Instituto de Biotecnologia,
42 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
27 - Vergara Bahena, Irene (2010). Influencia de la via de administracion en la capacidad neutralizante in vivo de dos antivenenos .
Instituto de Biotecnologia,
xi, 73 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
28 - Jimenez Martinez, Lucia (2009). Neutralizacion de esfingomielinasa D recombuinante de Loxosceles boneti con varias preparaciones derivadas de suero hiperinmune de caballo .
FMVZ,
Medico Veterinario Zootecnista,
UNAM.
*
Asesor: Alagon Cano, Alejandro
29 - Moctezuma Gonzalez, Claudia Lizbeth (2008). Produccion de un fragmento de anticuerpo recombinante quimerico anti esfingomielinasa D contra la mordedura de la arana Loxosceles.
Instituto de Biotecnologia,
53 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
30 - Chavez Mendez, Ariana (2007). Desarrollo, optimizacion y validacion de un metodo analitico tipo ELISA para cuantificar veneno de escorpion Centruroides en plasma humano .
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
Asesor: Alagon Cano, Alejandro
31 - Olguin Perez, Laura Patricia (2006). Caracterizacion de la actividad enzimatica de la esfingomielinasa D del veneno de las aranas violinistas Loxosceles boneti, L. reclusa Y L. laeta .
Instituto de Biotecnologia,
41, [2] paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
32 - Ramos Cerrillo, Blanca Margarita (2005). Produccion, evaluacion y caracterizacion de los inmunogenos recombinantes de las esfingomielinasa de L. boneti, L. reclusa y L. laeta .
Instituto de Biotecnologia,
(97, [15] paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
33 - Prud'Homme Sanchez, Monica Adriana (2004). Produccion y evaluacion de antigenos recombinantes de la alatrotoxina de Latrodectus mactans.
Instituto de Biotecnologia,
(vii, 77 paginas,
Maestria en Ciencias (Bioquimica),
UNAM.
Asesor: Alagon Cano, Alejandro
34 - Carbajal Saucedo, Alejandro (2004). Comparacion inmunoquimica del veneno de serpientes de coral (Elapidae : Mirurus, Micruroides) mexicanas .
Instituto de Biotecnologia,
53 paginas,
Maestria en Ciencias (Bioquimica),
UNAM.
Asesor: Alagon Cano, Alejandro
35 - Fuentes Silva, Deyanira (2003). Plegamiento in vitro de una toxina sintetica de arana.
Instituto de Biotecnologia,
76, VI paginas ,
Maestria en Ciencias Quimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
36 - Ramos Cerrillo, Blanca Margarita (2002). Comparacion bioquimica, inmunologica y toxinologica de los venenos de Loxosceles boneti y Loxosceles reclusa .
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
Asesor: Alagon Cano, Alejandro
37 - Ramos Ibarra, Marco Antonio (2001). Clonacion y localizacion intracelular de la subunidad de 54 kDa de la particula de reconocimiento de la secuencia senal (SRP54) de Entamoeba histolytica .
Instituto de Biotecnologia,
74, VII paginas,
Doctor en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
38 - Ortiz Suri, Ernesto (1998). Moleculas de PNA en sistemas fluorescentes de deteccion por hibridacion en la discriminacion de alelos .
Instituto de Biotecnologia,
56, [10] paginas,
Doctorado en Biotecnologia,
UNAM.
39 - Gonzalez Juarez, Carlos Antonio (1996). Desarrollo de una prueba diagnostica para la deteccion de hipotiroidismo congenito empleando anticuerpos monoclonales.
Instituto de Biotecnologia,
87, VI paginas,
Maestria en Biotecnologia,
UNAM.
Asesor: Alagon Cano, Alejandro
40 - Hernandez Vargas, Rene (1995). Caracterizacion molecular de un fragmento de un gene similar a HSP70 de Entamoeba histolytica.
Instituto de Biotecnologia,
57 paginas,
Maestria en Biotecnologia,
UNAM.
41 - Mercado Besserer, Gabriel Cuauhtemoc (1994). Obtencion y caracterizacion de un fragmento del gene SRP54 de Entamoeba histolytica.
Instituto de Biotecnologia,
Licenciatura en Investigacion Biomedica Basica,
UNAM.
42 - Herrera Medina, Enrique Macario (1992). Caracterizacion bioquimica del veneno de la hormiga Pogonomyrmex rugosus con enfasis en la fosfolipasa A1 .
Instituto de Biotecnologia,
53 paginas,
Maestria en Biotecnologia,
UNAM.
Asesor: Alagon Cano, Alejandro
43 - Cuevas Aguirre, Delia Anatolia (1992). Caracterizacion bioquimica de saliva de triatominos mexicanos.
Maestria en Biotecnologia,
UNAM.
44 - Vargas Villarreal, Javier (1991). Aislamiento y caracterizacion de una fosfolipasa A2 de Entamoeba histolytica con actividad litica directa .
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
64 paginas,
Doctorado en Investigacion Biomedica Basica,
UNAM.
Asesor: Alagon Cano, Alejandro
45 - Astorga Chaidez, Eleuterio (1991). Actividad inhibitoria de la agregacion plaquetaria por la saliva del murcielago hematofogo.
Instituto de Biotecnologia,
Maestría en Biotecnología,
UNAM.
Asesor: Alagon Cano, Alejandro
46 - Sosa Pineda, Beatriz (1988). Helodermatidina, una proteasa del veneno del monstruo de cuentas (heloderma horridum horridum) que activa plasminogeno .
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
42 paginas,
Maestria en Investigacion Biomedica Basica,
UNAM.
Asesor: Alagon Cano, Alejandro
47 - Amezcua Lopez, Jose (1987). Caracterizacion bioquimica del veneno de avispas Polistesdoxsalis (Fabricius) y Polivia occidentalis nigritella du Bysson.
Facultad de Ciencias,
UNAM.
*
Asesor: Alagon Cano, Alejandro
Total de publicaciones: 211
- Tipo
- Fecha
Artículo in press
48 - Alfaro-Chinchilla,A., Lomonte,B., Zuniga,L., Acevedo,M., Neri-Castro,E., Alagon,A., Bonilla,F., Diaz,C., Sasa,M. (2025). Venom composition, toxicity and cross-neutralization by PoliVal-ICP antivenom, of Mesoamerican jumping pitvipers genus Metlapilcoatlus (Viperidae: Crotalinae).
Transactions of the Royal Society of Tropical Medicine and Hygiene,
Advance access,
trae120.
Artículo
49 - Borja,M., Castaneda-Gaytan,G., Alagon,A., Strickland,J.L., Parkinson,C., Gutierrez-Martinez,A., Rodriguez-Lopez,B., Zarzosa,V., Lomonte,B., Saviola,A.J., Fernandez,J., Smith,C.F., Hansen,K.C., Perez-Robles,A., Castaneda-Perez,S., Hirst,S.R., Olvera-Rodriguez,F, Fernandez-Badillo,L, Sigala,J, Jones,J, Montano-Rubalcava,C, Ramirez-Chaparro,R., Margres,M., Acosta-Campana,G., Neri-Castro,E. (2025). Venom variation and ontogenetic changes in the Crotalus molossus complex: Insights into composition, activities, and antivenom neutralization.
Comparative Biochemistry and Physiology - C Toxicology and Pharmacology,
290,
110129.
Artículo
50 - Zarzosa,V., Neri-Castro,E., Lomonte,B., Fernandez,J., Rodriguez-Barrera,G., Rodriguez,B., Rodriguez-Solis,A.M., Olvera-Rodriguez,A., Benard-Valle,M., Saviola,A., Garcia-Vazquez,U.O., Fernandez-Badillo,L, Morales-Capellan,N., Borja,M., Zamudio,F., Alagon,A. (2025). Integrative transcriptomic, proteomic, biochemical and neutralization studies on the venom of Micrurus ephippifer.
Journal of Proteomics,
316,
105416.
Artículo
51 - Benard-Valle,M., Wouters,Y., Ljungars,A., Nguyen,G.T.T., Ahmadi,S., Ebersole,T.W., Dahl,C.H., Guadarrama-Martinez,A., Jeppesen,F., Eriksen,H., Rodriguez-Barrera,G., Boddum,K., Jenkins,T.P., Bjorn,S.P., Schoffelen,S., Voldborg,B.G., Alagon,A., Laustsen,A.H. (2024). In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model.
Nature Communications,
15 (1),
4310.
Artículo
52 - Bourke,L.A., Zdenek,C.N., Huynh,T.M., Hodgson,W.C., Alagon,A., Castro,E.N., Jones,J., Fry,B.G. (2024). Fangs and Foliage: Unearthing the Haemotoxic Secrets of Cannabis-Dwelling Rattlesnakes.
Toxicon,
244,
107756.
Artículo
53 - Campbell,S.I.D., Chow,C.Y., Neri-Castro,E., Alagon,A., Gomez,A., Soria,R., King,G.F., Fry,B.G. (2024). Taking the sting out of scorpions: Electrophysiological investigation of the relative efficacy of three antivenoms against medically significant Centruroides species.
Comparative Biochemistry and Physiology C Toxicology and Pharmacology,
283,
109977.
Artículo
54 - Dashevsky,D., Harris,R.J., Zdenek,C.N., Benard-Valle,M., Alagon,A., Portes-Junior,J.A., Tanaka-Azevedo,A.M., Grego,K.F., Sant'Anna,S.S., Frank,N., Fry,B.G. (2024). Red-on-Yellow Queen: Bio-Layer Interferometry Reveals Functional Diversity Within Micrurus Venoms and Toxin Resistance in Prey Species.
Journal of Molecular Evolution,
92,
317-328.
Artículo
55 - Guadarrama-Martinez,A., Neri-Castro,E., Boyer,L., Alagon,A. (2024). Variability in antivenom neutralization of Mexican viperid snake venoms.
PLoS Neglected Tropical Diseases,
18 (5),
e0012152.
Artículo
56 - Neri-Castro,E., Zarzosa,V., Benard-Valle,M., Rodriguez-Solis,A.M., Hernandez-Orihuela,L., Ortiz-Medina,J.A., Alagon,A. (2024). Quantifying venom production: A study on Micrurus snakes in Mexico.
Toxicon,
240,
107658.
Artículo
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127 - Neri-Castro,E., Lomonte,B., Gutierrez,M.C., Alagon,A., Gutierrez,J.M. (2013). Intraspecies variation in the venom of the rattlesnake Crotalus simus from Mexico: Different expression of crotoxin results in highly variable toxicity in the venoms of three subspecies.
Journal of Proteomics,
87,
103-121.
Artículo
128 - Oukkache,N., Chgoury,F., Lalaoui,M., Alagon-Cano,A., Ghalim,N. (2013). Comparison between two methods of scorpion venom milking in Morocco.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
19 (1),
5.
Artículo
129 - Vazquez,H., Olvera,F., Alagon,A., Sevcik,C. (2013). Production of anti-horse antibodies induced by IgG, F(ab') and Fab applied repeatedly to rabbits. Effect on antivenom pharmacokinetics.
Toxicon,
76,
362-369.
Artículo
130 - Clement,H., Olvera,A., Rodriguez,M., Zamudio,F., Palomares,L.A., Possani,L.D., Odell,G.V., Alagon,A., Sanchez-Lopez,R. (2012). Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom.
Toxicon,
60 (7),
1223-1227.
Artículo
131 - Clement,H., Costa de Oliveira,V, Zamudio,F.Z., Lago,N.R., Valdez-Cruz,N.A., Valle,M.B., Alagon,A.C., Possani,L.D., de Roodt,A.R. (2012). Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A(2) from Bothrops (Rhinocerophis) ammodytoides Venom.
Toxicon,
60 (7),
1314-1323.
Artículo
132 - Koludarov,I., Sunagar,K., Undheim,E.A., Jackson,T.N., Ruder,T., Whitehead,D., Saucedo,A.C., Mora,G.R., Alagon,A.C., King,G., Antunes,A., Fry,B.G. (2012). Structural and Molecular Diversification of the Anguimorpha Lizard Mandibular Venom Gland System in the Arboreal Species Abronia graminea.
Journal of Molecular Evolution,
75 (5-6),
168-183.
Artículo
133 - Paniagua,D., Jimenez,L., Romero,C., Vergara,I., Calderon,A., Benard,M., Bernas,M.J., Rilo,H., de Roodt,A., D'Suze,G., Witte,M.H., Boyer,L., Alagon,A. (2012). Lymphatic route of transport and pharmacokinetics of Micrurus fulvius (coral snake) venom in sheep.
Lymphology,
45 (4),
144-153.
Artículo
134 - Archundia,I.G., de Roodt,A.R., Ramos-Cerrillo,B., Chippaux,J.P., Olguin-Perez,L., Alagon,A., Stock,R.P. (2011). Neutralization of Vipera and Macrovipera venoms by two experimental polyvalent antisera: A study of paraspecificity.
Toxicon,
57 (7-8),
1049-1056.
Artículo
135 - Redaelli,E., Restano-Cassulini,R., Fuentes-Silva,D., Clement,H., Schiavon,E., Zamudio,F.Z., Odell,G., Arcangeli,A., Clare,J.J., Alagon,A., Rodriguez de la Vega,R.C., Possani,L.D., Wanke,E. (2010). Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.
Journal of Biological Chemistry,
285 (6),
4130-4142 .
Artículo
136 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2010). Pharmacokinetics of a F(ab')(2) scorpion antivenom administered intramuscularly in healthy human volunteers.
International Immunopharmacology,
10 (11),
1318-1324.
Artículo
137 - Vazquez,H., Olvera,F., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2010). Pharmacokinetics in rabbits and anti-sphingomyelinase D neutralizing power of Fab, F(ab')2, IgG and IgG(T) fragments from hyper immune equine plasma.
International Immunopharmacology,
10 (4),
447-454.
Artículo
138 - Boyer,L.V., Theodorou,A.A., Berg,R.A., Mallie,J., Chavez-Mendez,A., Garcia-Ubbelohde,W., Hardiman,S., Alagon,A. (2009). Antivenom for critically ill children with neurotoxicity from scorpion stings.
New England Journal of Medicine,
360 (20),
2090-2098 (Reply 2009 vol 361 632).
Artículo
139 - Casasola,A., Ramos-Cerrillo,B., de Roodt,A.R., Saucedo,A.C., Chippaux,J.P., Alagon,A., Stock,R.P. (2009). Paraspecific neutralization of the venom of African species of cobra by an equine antiserum against Naja melanoleuca: A comparative study.
Toxicon,
53 (6),
602-608.
Artículo
140 - Chase,P., Boyer-Hassen,L., McNally,J., Vazquez,H.L., Theodorou,A.A., Walter,F.G., Alagon,A. (2009). Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients.
Clinical Toxicology,
47 (1),
24-28.
Artículo
141 - Corzo,G., Bernard,C., Clement,H., Villegas,E., Bosmans,F., Tytgat,J., Possani,L.D., Darbon,H., Alagon,A. (2009). Insecticidal peptides from the theraposid spider Brachypelma albiceps: A NMR-based model of Ba2.
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics,
1794 (8),
1190-1196.
Artículo
142 - Chippaux,J.P., Alagon,A. (2008). [Envenomation and poisoning by venomous or poisonous animals. VII: arachnidism in the New World].
Medecine Tropicale,
68 (3),
215-221.
Artículo
143 - Corzo,G., Diego-Garcia,E., Clement,H., Peigneur,S., Odell,G., Tytgat,J., Possani,L.D., Alagon,A. (2008). An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.
Peptides,
29 (11),
1901-1908.
Artículo
144 - Ramos-Cerrillo,B., de Roodt,A.R., Chippaux,J.P., Olguin,L., Casasola,A., Guzman,G., Paniagua-Solis,J., Alagon,A., Stock,R.P. (2008). Characterization of a new polyvalent antivenom (Antivipmyn((R)) Africa) against African vipers and elapids.
Toxicon,
52 (8),
881-888.
Artículo
145 - Chippaux,J.P., Massougbodji,A., Stock,R.P., Alagon,A. (2007). Clinical Trial of an F(ab')2 Polyvalent Equine Antivenom for African Snake Bites in Benin.
American Journal of Tropical Medicine and Hygiene,
77 (3),
538-546.
Artículo
146 - Clement,H., Odell,G., Zamudio,F.Z., Redaelli,E., Wanke,E., Alagon,A., Possani,L.D. (2007). Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels.
Toxicon,
50 (1),
65-74.
Artículo
147 - de Roodt,A.R., Estevez-Ramirez,J., Litwin,S., Magana,P., Olvera,A., Alagon,A. (2007). Toxicity of two North American Loxosceles (brown recluse spiders) venoms and their neutralization by antivenoms.
Clinical Toxicology,
45 (6),
678-687.
Carta
148 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R., Algaron,A., Fox,J.W. (2007). Upregulation of IL-6, IL-8, CXCL1, and CXCL2 Dominates Gene Expression in Human Fibroblast Cells Exposed to Loxosceles reclusa Sphingomyelinase D: Insights into Spider Venom Dermonecrosis.
Journal of Investigative Dermatology,
127 (5),
1264-1266.
Carta
149 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R.P., Alagon,A., Fox,J.W. (2007). Upregulation of cytokine expression in fibroblasts exposed to Loxosceles sphingomyelinase D: What is the trigger? - Response to Moolenaar et al.
Journal of Investigative Dermatology,
127 (5),
1267-1268.
Artículo
150 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Alagon,A. (2007). Antigenic cross-reactivity between sixteen venoms from scorpions belonging to six genera.
Clinical Toxicology,
45 (2),
158-163.
Artículo
151 - Almagro,J.C., Martinez,L., Smith,S.L., Alagon,A., Estevez,J., Paniagua,J. (2006). Analysis of the horse V(H) repertoire and comparison with the human IGHV germline genes, and sheep, cattle and pig V(H) sequences.
Molecular Immunology,
43 (11),
1836-1845.
Artículo
152 - Olvera,A., Ramos-Cerrillo,B., Estevez,J., Clement,H., de Roodt,A., Paniagua-Solis,J., Vazquez,H., Zavaleta,A., Salas-Arruz,M., Stock,R.P., Alagon,A. (2006). North and South American Loxosceles spiders: Development of a polyvalent antivenom with recombinant sphingomyelinases D as antigens.
Toxicon,
48 (1),
64-74.
Artículo
153 - de Roodt,A.R., Estevez-Ramirez,J., Paniagua-Solis,J.F., Litwin,S., Carvajal-Saucedo,A., Dolab,J.A., Robles-Ortiz,L.E., Alagon,A. (2005). [Toxicity of venoms from snakes of medical importance in Mexico].
Gaceta Medica de Mexico,
141 (1),
13-21.
Artículo
154 - de Roodt,A.R., Salomon,O.D., Orduna,T.A., Robles-Ortiz,L.E., Paniagua-Solis,J.F., Cano,A.A. (2005). Poisoning by bee sting.
Gaceta Medica de Mexico,
141 (3),
215-222.
Artículo
155 - Ramos,M.A., Sanchez-Lopez,R., Mares,R.E., Olvera,F., Alagon,A. (2005). Identification of an Entamoeba histolytica gene encoding a protein disulfide isomerase that functionally complements the dsbA mutation in Escherichia coli.
Molecular and Biochemical Parasitology,
143 (2),
236-240.
Artículo
156 - Sadurni,P., Alagon,A., Aliev,R., Burillo,G., Hoffman,A.S. (2005). Immobilization of streptavidin-horseradish peroxidase onto a biotinylated poly(acrylic acid) backbone that had been radiation-grafted to a PTFE film.
Journal of Biomaterials Science-Polymer Edition,
16 (2),
181-187.
Artículo
157 - Salgado,M., Villagomez-Castro,J.C., Rocha-Rodriguez,R., Sabanero-Lopez,M., Ramos,M.A., Alagon,A., Lopez-Romero,E., Sanchez-Lopez,R. (2005). Entamoeba histolytica: Biochemical and molecular insights into the activities within microsomal fractions.
Experimental Parasitology,
110 (4),
363-373.
Artículo
158 - Sanchez,R., Saralegui,A., Olivos-Garcia,A., Scapolla,C., Damonte,G., Sanchez-Lopez,R., Alagon,A., Stock,R.P. (2005). Entamoeba histolytica: intracellular distribution of the sec61alpha subunit of the secretory pathway and down-regulation by antisense peptide nucleic acids.
Experimental Parasitology,
109 (4),
241-251.
Artículo
159 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Mancilla-Nava,R., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2005). Pharmacokinetics of a F(ab')(2) scorpion antivenom in healthy human volunteers.
Toxicon,
46 (7),
797-805.
Artículo
160 - de Roodt,A.R., Paniagua-Solis,J.F., Dolab,J.A., Estevez-Ramirez,J., Ramos-Cerrillo,B., Litwin,S., Dokmetjian,J.C., Alagon,A. (2004). Effectiveness of two common antivenoms for North, Central, and South American Micrurus envenomations.
Journal of Toxicology - Clinical Toxicology,
42 (2),
171-178.
Artículo
161 - Ramos-Cerrillo,B., Olvera,A., Odell,G.V., Zamudio,F., Paniagua-Solis,J., Alagon,A., Stock,R.P. (2004). Genetic and enzymatic characterization of sphingomyelinase D isoforms from the North American fiddleback spiders Loxosceles boneti and Loxosceles reclusa.
Toxicon,
44 (5),
507-514 .
Artículo
162 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Aguilar,V., Alagon,A. (2003). Relationship between plasmatic levels of various cytokines, tumour necrosis factor, enzymes, glucose and venom concentration following Tityus scorpion sting.
Toxicon,
41 (3),
367-375.
Artículo
163 - Nieto-Sotelo,J., Martinez,L.M., Ponce,G., Cassab,G.I., Alagon,A., Meeley,R.B., Ribaut,J.M., Yang,R. (2002). Maize HSP101 Plays Important Roles in Both Induced and Basal Thermotolerance and Primary Root Growth.
Plant Cell,
14 (7),
1621-1633.
Artículo
164 - Ramos,M.A., Sanchez-Lopez,R., Olvera,F., Alagon,A. (2002). Entamoeba histolytica genomic organization: identification, structure, and phylogenetic relationship of two serine-threonine protein kinases.
Experimental Parasitology,
100 (2),
135-139.
Artículo
165 - Sanchez,R., Alagon,A., Stock,R.P. (2002). Entamoeba histolytica: intracellular distribution of the proteasome.
Experimental Parasitology,
102 (3-4),
187-190.
Artículo
166 - Juarez,P., Sanchez-Lopez,R., Stock,R.P., Olvera,A., Ramos,M.A., Alagon,A. (2001). Characterization of the Ehrab8 gene, a marker of the late stages of the secretory pathway of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
116 (2),
223-228.
Artículo
167 - Stock,R.P., Olvera,A., Sanchez,R., Saralegui,A., Scarfi,S., Sanchez-Lopez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Alagon,A. (2001). Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers.
Nature Biotechnology,
19 (3),
231-234.
Artículo
168 - Gutierrez,A., Sanchez-Lopez,R., Ramos,M.A., Alagon,A. (2000). Cloning of the Entamoeba histolytica STT3 gene, a subunit of the oligosaccharyltransferase complex.
Archives of Medical Research,
31 (4 Suppl),
S162-S164.
Artículo
169 - Juarez,P., Sanchez-Lopez,R., Ramos,M.A., Stock,R.P., Alagon,A. (2000). Rab8 as a molecular model of vesicular trafficking to investigate the latter steps of the secretory pathway in Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S157-S159.
Artículo
170 - Ramos,M.A., Alagon,A. (2000). Molecular cloning of a gene encoding a PDI-like protein from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S173-S175.
Artículo
171 - Ramos,M.A., Sanchez-Lopez,R., Alagon,A. (2000). Genomic organization of a 7 Kb gene cluster from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S263-S265.
Artículo
172 - Sanchez-Lopez,R., Gutierrez,A., Juarez,P., Olvera,A., Olvera,F., Ramos,M.A., Sanchez,R., Saralegui,A., Stock,R.P., Alagon,A. (2000). Molecular genetics of the secretory pathway in Entamoeba histolytica: an overview.
Archives of Medical Research,
31 (4 Suppl),
S151-S152.
Artículo
173 - Sanchez-Lopez,R., Siminovich,B., Alagon,A. (2000). Entamoeba histolytica codes for a protein homologue of the Sec61 alpha subunit, a component of the endoplasmic reticulum translocon.
Archives of Medical Research,
31 (4 Suppl),
S168-S170.
Artículo
174 - Stock,R.P., Olvera,A., Scarfi,S., Sanchez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Landt,O., Alagon,A. (2000). Inhibition of neomycin phosphorotransferase expression in Entamoeba histolytica with antisense peptide nucleic acid (PNA) oligomers.
Archives of Medical Research,
31 (4 Suppl),
S271-S272.
Artículo
175 - Que,X., Kim,D., Alagon,A., Hirata,K., Shike,H., Shimizu,C., Gonzalez,A., Burns,J.C., Reed,S.L. (1999). Pantropic retroviral vectors mediate gene transfer and expression in Entamoeba histolytica.
Molecular and Biochemical Parasitology,
99 (2),
237-245.
Artículo
176 - Sanchez-Gonzalez,M., Alagon,A., Rodriguez-Sotres,R., Lopez-Munguia,A. (1999). Proteolytic processing of dextransucrase of Leuconostoc mesenteroides.
Fems Microbiology Letters,
181 (1),
25-30.
Artículo
177 - Sanchez-Lopez,R., Gama-Castro,S., Ramos,M.A., Merino,E., Lizardi,P.M., Alagon,A. (1998). Cloning and expression of the Entamoeba histolytica ERD2 gene.
Molecular and Biochemical Parasitology,
92 (2),
355-359.
Artículo
178 - Vargas-Villarreal,J., Olvera-Rodriguez,A., Mata-Cardenas,B.D., Martinez-Rodriguez,H.G., Said-Fernandez,S., Alagon-Cano,A. (1998). Isolation of an Entamoeba histolytica intracellular alkaline phospholipase A(2).
Parasitology Research,
84 (4),
310-314.
Artículo; Actas Paper
Artículo
180 - Ramos,M.A., Mercado,G.C., Salgado,L.M., Sanchez-Lopez,R., Stock,R.P., Lizardi,P.M., Alagon,A. (1997). Entamoeba histolytica contains a gene encoding a homologue to the 54 kDa subunit of the signal recognition particle.
Molecular and Biochemical Parasitology,
88 (1-2),
225-235.
Artículo; Actas Paper
181 - Ramos,M.A., Stock,R.P., Lizardi,P.M., Alagon,A. (1997). The secretory pathway of Entamoeba histolytica: characterization and expression of the SRP54 gene.
Archives of Medical Research,
28 (Spec No:56-8.),
56-58.
Artículo
182 - Ramos,M.A., Stock,R.P., Sanchez-Lopez,R., Olvera,F., Lizardi,P.M., Alagon,A. (1997). The Entamoeba histolytica proteasome alpha-subunit gene.
Molecular and Biochemical Parasitology,
84 (1),
131-135.
Artículo; Actas Paper
183 - Sanchez-Lopez,R., Gama-Castro,S., Lizardi,P.M., Alagon,A. (1997). The secretory pathway of Entamoeba histolytica: characterization and expression of the ERD2 gene.
Archives of Medical Research,
28 (Spec No:59-61.),
59-61.
Artículo
184 - Estrada,G., Colin,L., Gaytan,P., Alagon,A., Lizardi,P.M. (1996). Sequence-specific detection of PCR-amplified DNA by restriction enzyme release of hybrids.
Molecular and cellular probes,
10 (3),
179-185.
Artículo
185 - Miranda,R., Salgado,L.M., Sanchez-Lopez,R., Alagon,A., Lizardi,P.M. (1996). Identification and analysis of the u6 small nuclear RNA gene from Entamoeba histolytica.
Gene,
180 (1-2),
37-42.
Artículo
186 - Ortega-Pierres,G., Alagon,A., Cortes,A., Olvera,F., Olvera,A., Gonzalez,A., Lizardi,P., Berzunza-Cruz,M., Saavedra-Lira,E., Perez-Montfort,R., Velasco-Castrejon,O., Sotero-Delgado Dominguez,I., Becker,I., Hernandez,R., Martinez-Calvillo,S., Frixione,E., Ruiz,L., Santillan,M., Vega,L., Tejero,J.M., Undeen,A.H., Kretschmer,R.R., Herion,P., Saavedra,R., Yepez-Mulia,L. (1996). [Impact of new methodologies in the study of parasites].
Gaceta Medica de Mexico,
132 (5),
475-517.
Artículo
187 - Michel,B., Lizardi,P.M., Alagon,A., Zurita,M. (1995). Identification and analysis of the start site of ribosomal RNA transcription of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
73 (1-2),
19-30.
Artículo
188 - Noeske-Jungblut,C., Haendler,B., Donner,P., Alagon,A., Possani,L., Schleuning,W.D. (1995). Triabin, a highly potent exosite inhibitor of thrombin.
Journal of Biological Chemistry,
270 (48),
28629-28634.
Artículo
189 - Noeske-Jungblut,C., Kratzschmar,J., Haendler,B., Alagon,A., Possani,L., Verhallen,P., Donner,P., Schleuning,W.D. (1994). An inhibitor of collagen-induced platelet aggregation from the saliva of Triatoma pallidipennis.
Journal of Biological Chemistry,
269 (7),
5050-5053.
Artículo
190 - Palmeros,B., Guereca,L., Alagon,A., Soberon-Chavez,G. (1994). Biochemical characterization of the lipolytic activity of pseudomonas aeruginosa IGB 83.
Process Biochemistry,
29 (3),
207-212.
Artículo
191 - Cevallos,M.A., Porta,H., Alagon,A.C., Lizardi,P.M. (1993). Sequence of the 5.8S ribosomal gene of pathogenic and non-pathogenic isolates of Entamoeba histolytica.
Nucleic Acids Research,
21 (2),
355-355.
Note
192 - Cevallos,M.A., Navarro-Duque,C., Varela-Julia,M., Alagon,A.C. (1992). Molecular mass determination and assay of venom hyaluronidases by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Toxicon,
30 (8),
925-930.
Note
193 - Michel,B., Alagon,A., Lizardi,P.M., Zurita,M. (1992). Characterization of a repetitive DNA element from Entamoeba histolytica.
Molecular and Biochemical Parasitology,
51 (1),
165-168.
Artículo
194 - Possani,L.D., Fletcher,P.L., Fletcher,M.D., Rode,G.S., Mochca-Morales,J., Lucas,S., Coronas,F.V., Alagon,A.C., Martin,B.M. (1992). Structural and functional characteristics of toxins purified from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello.
Memorias do Instituto Butantan,
54 (2),
35-52.
Artículo
195 - Schleuning,W.D., Alagon,A., Boidol,W., Bringmann,P., Petri,T., Kratzschmar,J., Haendler,B., Langer,G., Baldus,B., Witt,W. (1992). Plasminogen activators from the saliva of Desmodus rotundus (common vampire bat): unique fibrin specificity.
Annals of the New York Academy of Sciences,
667,
395-403.
*
Artículo
196 - Kratzschmar,J., Haendler,B., Langer,G., Boidol,W., Bringmann,P., Alagon,A., Donner,P., Schleuning,W.D. (1991). The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression.
Gene,
105 (2),
229-237.
Note
197 - Vargas-Villarreal,J., Martin-Polo,J.J., Reynaud,E., Alagon,A.C. (1991). A new affinity adsorbent for the purification of phospholipases A1 and A2 from animal venoms.
Toxicon,
29 (1),
119-124.
Artículo
198 - Zurita,M., Alagon,A., Vargas-Villarreal,J., Lizardi,P.M. (1991). The Entamoeba histolytica rDNA episome: nuclear localization, DNAase I sensitivity map, and specific DNA-protein interactions.
Molecular Microbiology,
5 (8),
1843-1851.
Note
199 - Laclette,J.P., Alagon,A., Willms,K., Torre-Blanco,A. (1990). Purification of antigen B from Taenia solium cysticerci by affinity to mammalian collagen.
Journal of Parasitology,
76 (2),
273-275.
Artículo
200 - Alagon,A.C., Guzman,H.S., Martin,B.M., Ramirez,A.N., Carbone,E., Possani,L.D. (1988). Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch.
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology,
89 (1),
153-161.
Artículo
201 - Alagon,A., Possani,L.D., Smart,J., Schleuning,W.D. (1986). Helodermatine, a kallikrein-like, hypotensive enzyme from the venom of Heloderma horridum horridum (Mexican beaded lizard).
Journal of Experimental Medicine,
164 (6),
1835-1845.
Artículo
202 - Sosa,B.P., Alagon,A.C., Martin,B.M., Possani,L.D. (1986). Biochemical characterization of the phospholipase A2 purified from the venom of the Mexican beaded lizard (Heloderma horridum horridum Wiegmann).
Biochemistry,
25 (10),
2927-2933.
*
Artículo
203 - King,T.P., Alagon,A.C., Kuan,J., Sobotka,A.K., Lichtenstein,L.M. (1983). Immunochemical studies of yellowjacket venom proteins.
Molecular Immunology,
20 (3),
297-308.
*
Artículo
204 - Alagon,A.C., Maldonado,M.E., Julia,J.Z., Sanchez,C.R., Possani,L.D. (1982). Venom from two sub-species of Heloderma horridum (Mexican beaded lizard): general characterization and purification of N-benzoyl-L-arginine ethyl ester hydrolase.
Toxicon,
20 (2),
463-475.
*
Artículo
205 - King,T.P., Alagon,A., Kochoumian,L., Kuan,J., Sobotka,A., Lichtenstein,L.M. (1981). Limited proteolysis of antigens E and K from ragweed pollen.
Archives of Biochemistry and Biophysics,
212 (1),
127-135.
*
Artículo
206 - Possani,L., Steinmetz,W.E., Dent,M.A., Alagon,A.C., Wuthrich,K. (1981). Preliminary spectroscopic characterization of six toxins from Latin American scorpions.
Biochimica et Biophysica Acta (BBA) - Protein Structure,
669 (2),
183-192.
*
Artículo
207 - Alagon,A.C., King,T.P. (1980). Activation of polysaccharides with 2-iminothiolane and its uses.
Biochemistry,
19 (18),
4341-4345.
*
Artículo
208 - Alagon,A.C., Molinar,R.R., Possani,L.D., Fletcher,P.L., Cronan,J.E., Julia,J.Z. (1980). Venom from the snake Bothrops asper Garman. Purification and characterization of three phospholipases A2.
Biochemical Journal,
185 (3),
695-704.
*
Artículo
209 - Possani,L.D., Fletcher,P.L., Alagon,A.B., Alagon,A.C., Julia,J.Z. (1980). Purification and characterization of a mammalian toxin from venom of the Mexican scorpion, Centruroides limpidus tecomanus Hoffmann.
Toxicon,
18 (2),
175-183.
*
Note
210 - Possani,L.D., Sosa,B.P., Alagon,A.C., Burchfield,P.M. (1980). The venom from the snakes Agkistrodon bilineatus Taylori and Crotalus durissus Totonacus: lethality, biochemical and immunological properties.
Toxicon,
18 (3),
356-360.
*
Artículo
211 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Varela,M.J., Julia,J.Z. (1979). Purification and characterization of a phospholipase A2 from the venom of the coral snake, Micrurus fulvius microgalbineus (Brown and Smith).
Biochemical Journal,
179 (3),
603-606.
*
Artículo
212 - Sosa,B.P., Alagon,A.C., Possani,L.D., Julia,J.Z. (1979). Comparison of phospholipase activity with direct and indirect lytic effects of animal venoms upon human red cells.
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry,
64 (2),
231-234.
*
Artículo
213 - King,T.P., Sobotka,A.K., Alagon,A., Kochoumian,L., Lichtenstein,L.M. (1978). Protein allergens of white-faced hornet, yellow hornet, and yellow jacket venoms.
Biochemistry,
17 (24),
5165-5174.
*
Artículo
214 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Erickson,B.W. (1977). Purification and properties of mammalian toxins from the venom of Brazilian Scorpion Tityus serrulatus Lutz and Mello.
Archives of Biochemistry and Biophysics,
180 (2),
394-403.
*
Artículo
215 - Frenk,J., Acuna,D.L., Bobadilla,J.L., Alagon,A. (1976). [Liberal medicine and institutional medicine in Mexico].
Salud Publica de Mexico,
18 (3),
481-493.
*
Capítulo nacional
216 - Nares-Torices,M.A., Olguin-Sanchez,E., Rodrigues-Alvarez,D., Alagon-Cano,A., Sanchez-Villegas,M.C.S. (2021). Loxoscelismo. Una Mirada a la Toxinologia de Mexico.
35-58,
Ciudad de Mexico: Cognitio Journal.
Capítulo internacional
217 - Neri-Castro,E., Benard-Valle,M., Lopez de Leon,J., Boyer,L., Alagon,A. (2021). Envenomations by Reptiles in Mexico. Handbook of Venoms and Toxins of Reptiles 2a.
529-542,
2a.
Nacional
218 - Neri-Castro,E., Reyna,M.A., Alagon-Cano,A. (2021). Serpientes Venenosas. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
384-396,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
Nacional
219 - Reyna-Rojas,M.A., Neri-Castro,E.E., Alagon-Cano,A. (2021). Uso, manejo y percepción de herpetofauna en dos localidades del municipio de Tlaltizap án. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
398-411,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
Nacional
220 - Neri-Castro,E.E., Alagon-Cano,A. (2020). Reptiles venenosos: veneno y tratamiento. Biodiversidad en Morelos. Estudio de estado 2, vol 2.
306-310,
2,
Mexico: CONABIO.
Nacional
221 - Alagon,A. (2019). Biotecnología de antivenenos mexicana. Manos que sanan. Avances en la medicina potosina.
185-187,
San Luis Potosí, México: Graphstyle Publishers.
Internacional
222 - Paniagua, D., Vergara, I., Boyer, L., Alagon, A. (2017). Role of Lymphatic System on Snake Venom Absorption. Snake Venoms. Toxicology Series.
453-474,
Dordrecht.
Internacional
223 - Benard-Valle,M., Neri,E., Fry,B., Boyer,L., Cochran,C., Alam,M., Jackson,T.N.W., Paniagua,D., Sheira,D., Olvera-Rodriguez,F., Koludorov,I., Sunagar,K., Alagon,A. (2015). Antivenom research and development. Venomous reptiles and their toxins: Evolution, pathophysiology and biodiscovery .
61-72,
New York.
Internacional
224 - Boyer,L., Alagon,A., Fry,B.G., Jackson,T.N.W., Sunagar,K., Chippaux,J.P. (2015). Signs, symptoms and treatment of envenomation. Venomous Reptiles and Their Toxins: Evolution, Pathophysiology and Biodiscovery.
32-60,
New York: Oxford University Press.
Internacional
225 - Paniagua,D., Vergara,I., Boyer,L., Alagon,A. (2015). Role of Lymphatic System on Snake Venom Absorption. Snake Venoms.
Toxinology,
1-19.
Nacional
226 - Alagon,A., Odell,G. (2011). La biologia y taxonomia de las aranas americanas. Emergencias por Animales Ponzonosos en las Americas .
181-201,
Mexico: Instituto Bioclon & Laboratorios Silanes.
Nacional
227 - Alagon,A., Possani,L.D. (2003). Desarrollo de nuevos f rmacos a partir de la fauna tropical. Fronteras de la Biología en los Inicios del Siglo XXI, Módulo VII .
123-160,
Mexico,D.F..
Nacional
228 - Estrada,G., Sanchez,R., Lizardi,P.M., Alagon,A. (1998). Entamoeba histolytica y la reaccion en cadena de polimerasa por hibridazion y liberacion enzimatica (PCR-HERA). Biologia molecular en medicina.
Coleccion de textos politecnicos, series biotecnologicas.,
47-60,
Mexico DF.
Internacional
229 - Dehesa-Davila,M., Alagon,A.C., Possani,L.D. (1995). Clinical toxicology of scorpion stings. Handbook of clinical toxicology of animal venoms and poisons.
221-238,
New York.
Nacional
230 - Alagon,A., Carillo,C., Chavez-Haro,A., De la Mora-Zerpa,C., Larralde,C., Lamas,N, Martin,E, Osnaya-Romero,N., Perez,Y, Possani,L.D., Romero-Zamora,L. (2003). Práctica Médica Efectiva- Alacranismo (T63.2, X22).
Mexico.
Nacional divulgacion
231 - Alagon Cano,A. (2023). Antivenenos contra animales ponzoñosos: una historia de aventuras científicas y de éxitos para México.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
9 (32).
Nacional Case report
232 - Madrigal-Anaya,J.C., Cruz-Ibarra,A., Rodriguez-Uvalle,N.C., Gil-Alarcon,G., Alagon,A., Rodriguez-Flores,G., Boyer,L., Neri-Castro,E. (2022). A case of exotic envenomation by Naja kaouthia in Mexico.
Latin American Journal of Clinical Sciences and Medical Technology,
4,
1-8.
nacional divulgación
233 - Neri-Castro,E., Alagon-Cano,A. (2021). Descubrimientos recientes: Venenos de serpientes.
Hypatia,
66.
nacional divulgacion
Nacional Editorial
235 - Neri-Castro,E.E., Benard-Valle,M., Gil,J., Lopez de Leon J., Borja,M., Alagon,A. (2020). Serpientes venenosas en México: una revisión al estudio de los venenos, los antivenenos y la epidemiología .
Revista Latinoamericana de Herpetologia,
3 (2),
5-22.
Preprint
236 - Montes-Grajales,D., Jimenez,B., Rogel,M.A., Alagon,A., Esturau-Escofet,N., Esquivel,B., Martinez-Romero,J., Martinez-Romero,E. (2019). Nitrogen-fixing Klebsiella variicola in feces from herbivorous tortoises.
bioRxiv,
Preprint posted June 10, 2019,
666818.
Divulgación
237 - Reyna-Rojas,M.A., Garcia-Flores,A., Neri-Castro,E., Alagon-Cano,A., Monroy-Martinez,R. (2015). Conocimiento etnoherpetológico de dos comunidades aledañas a la reserva estatal sierra de montenegro, Morelos, Mexico.
Etnobiologia,
13 (2),
37-48.
Divulgación
238 - Corzo-Burguete,G., Alagon-Cano,A., Clement-Carretero,H., Jurado-Reyes,S.M., Herrera-Herrera,E. (2014). Los venenos de tar ntulas y la absorción de medicinas en nuestro cuerpo.
Hypatia,
48 (2).
Divulgación
239 - Neri-Castro,E., Benard-Valle,M., Alagon-Cano,A. (2014). Reptiles venenosos en M?xico.
Revista Digital Universitaria,
15 (11),
art 86.
Divulgación
Divulgación
241 - Alagon-Cano,A., Corzo,G., Clement-Carretero,H., Garcia-Garcia,F. (2010). Arañas: venenos con potencial biotecnológico.
Hypatia,
33.
Divulgación
242 - Rodriguez,M., Prud`Homme,M., Alagon,A., Stock,R. (2009). Expresión de a-latrotoxina Recombinante Activa de Latrodectus mactans Utilizando el Sistema de Células de Insecto-Baculovirus.
BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria,
13 (2),
34-47.
Nacional
243 - Mata-Gonzalez,M.T., Garcia-Ubbelohde,W., Alagon-Cano,A., Paniagua-Solis,J. (2008). Anticuerpos monoclonales para uso terap?utico en humanos.
Informaceutico Mexico,
15 (9-10),
30-36.
Nacional
244 - Rendon-Anaya,M., Alagon,A. (2008). Mecanismos moleculares de diversificación de inmunoglobulinas.
Revista de Educación Bioquímica,
27 (1),
19-29.
Biographical-Item
245 - Alagon,A., Clement-Carretero,H., Lomonte,B., Gutierrez,J.M., Ownby,C.L. (2007). Obituary of George V. Odell, 1926-2006.
Toxicon,
49 (6),
886-887.
Divulgación
246 - Olvera-Rodriguez,A., Alagon-Cano,A., Ramos-Cerrillo,B., Cardoso-Torres,H.M., Olvera-Rodriguez,F. (2007). La partitura de la araña violinista: Envenenamiento fatal.
Hypatia,
22.
Editorial Material
247 - Stock,R.P., Massougbodji,A., Alagon,A., Chippaux,J.P. (2007). Bringing antivenoms to Sub-Saharan Africa.
Nature Biotechnology,
25 (2),
173-177.
News Item
248 - Chippaux,J.P., Stock,R.P., Alagon,A. (2005). Report of the 2nd international conference on envenomations in Africa (Deuxieme colloque international sur les envenomations en Afrique).
Toxicon,
46 (1),
115-118.
Divulgación
Divulgación
Divulgación
251 - Alagon,A. (2002). Anticuerpos seguros y eficaces: la revoluacion de los nuevos antivenenos.
Revista Universidad de Mexico,
617.
Divulgación
Divulgación
253 - Ramos,M.A., Alagon,A. (2001). Ruta secretoria y Entamoeba histolytica.
Mensaje Bioquimico,
25,
111-128.
Nacional
254 - Estrada-Galvan,B., Scheinvar,L., Alagon,A., Olalde-Parra,G. (2000). Resultados preliminares de electroforesis en proteínas como método auxiliar en la taxonomía de Opuntia spp.
Acta Cientifica Potosina,
15 (1),
7-24.
Nacional
Nacional
256 - Arauco,R., Alagon,A. (1979). [Propanolol in arterial hypertension. Beta-blockaders. Recent advances].
Prensa médica mexicana,
44 (5-6),
97-104.
*
257 - Alagon Cano, Alejandro (1988). Enzimas hidroliticas del veneno de heloderma horridum horridum : fosfolipasa A2 y calicreina .
Doctorado en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
258 - Alagon Cano, Alejandro (1980). Estudio sobre los venenos de varias especies zoologicas.
Instituto de Investigacions Biomedicas,
Maestria en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
Artículo in press
259 - Alfaro-Chinchilla,A., Lomonte,B., Zuniga,L., Acevedo,M., Neri-Castro,E., Alagon,A., Bonilla,F., Diaz,C., Sasa,M.. Venom composition, toxicity and cross-neutralization by PoliVal-ICP antivenom, of Mesoamerican jumping pitvipers genus Metlapilcoatlus (Viperidae: Crotalinae).
Transactions of the Royal Society of Tropical Medicine and Hygiene,
Advance access,
trae120.
Artículo
260 - Borja,M., Castaneda-Gaytan,G., Alagon,A., Strickland,J.L., Parkinson,C., Gutierrez-Martinez,A., Rodriguez-Lopez,B., Zarzosa,V., Lomonte,B., Saviola,A.J., Fernandez,J., Smith,C.F., Hansen,K.C., Perez-Robles,A., Castaneda-Perez,S., Hirst,S.R., Olvera-Rodriguez,F, Fernandez-Badillo,L, Sigala,J, Jones,J, Montano-Rubalcava,C, Ramirez-Chaparro,R., Margres,M., Acosta-Campana,G., Neri-Castro,E.. Venom variation and ontogenetic changes in the Crotalus molossus complex: Insights into composition, activities, and antivenom neutralization.
Comparative Biochemistry and Physiology - C Toxicology and Pharmacology,
290,
110129.
Artículo
261 - Zarzosa,V., Neri-Castro,E., Lomonte,B., Fernandez,J., Rodriguez-Barrera,G., Rodriguez,B., Rodriguez-Solis,A.M., Olvera-Rodriguez,A., Benard-Valle,M., Saviola,A., Garcia-Vazquez,U.O., Fernandez-Badillo,L, Morales-Capellan,N., Borja,M., Zamudio,F., Alagon,A.. Integrative transcriptomic, proteomic, biochemical and neutralization studies on the venom of Micrurus ephippifer.
Journal of Proteomics,
316,
105416.
Artículo
262 - Benard-Valle,M., Wouters,Y., Ljungars,A., Nguyen,G.T.T., Ahmadi,S., Ebersole,T.W., Dahl,C.H., Guadarrama-Martinez,A., Jeppesen,F., Eriksen,H., Rodriguez-Barrera,G., Boddum,K., Jenkins,T.P., Bjorn,S.P., Schoffelen,S., Voldborg,B.G., Alagon,A., Laustsen,A.H.. In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model.
Nature Communications,
15 (1),
4310.
Artículo
263 - Bourke,L.A., Zdenek,C.N., Huynh,T.M., Hodgson,W.C., Alagon,A., Castro,E.N., Jones,J., Fry,B.G.. Fangs and Foliage: Unearthing the Haemotoxic Secrets of Cannabis-Dwelling Rattlesnakes.
Toxicon,
244,
107756.
Artículo
264 - Campbell,S.I.D., Chow,C.Y., Neri-Castro,E., Alagon,A., Gomez,A., Soria,R., King,G.F., Fry,B.G.. Taking the sting out of scorpions: Electrophysiological investigation of the relative efficacy of three antivenoms against medically significant Centruroides species.
Comparative Biochemistry and Physiology C Toxicology and Pharmacology,
283,
109977.
Artículo
265 - Dashevsky,D., Harris,R.J., Zdenek,C.N., Benard-Valle,M., Alagon,A., Portes-Junior,J.A., Tanaka-Azevedo,A.M., Grego,K.F., Sant'Anna,S.S., Frank,N., Fry,B.G.. Red-on-Yellow Queen: Bio-Layer Interferometry Reveals Functional Diversity Within Micrurus Venoms and Toxin Resistance in Prey Species.
Journal of Molecular Evolution,
92,
317-328.
Artículo
266 - Guadarrama-Martinez,A., Neri-Castro,E., Boyer,L., Alagon,A.. Variability in antivenom neutralization of Mexican viperid snake venoms.
PLoS Neglected Tropical Diseases,
18 (5),
e0012152.
Artículo
267 - Neri-Castro,E., Zarzosa,V., Benard-Valle,M., Rodriguez-Solis,A.M., Hernandez-Orihuela,L., Ortiz-Medina,J.A., Alagon,A.. Quantifying venom production: A study on Micrurus snakes in Mexico.
Toxicon,
240,
107658.
Artículo
268 - Neri-Castro,E., Zarzosa,V., Lomonte,B., Zamudio,F., Hernandez-Orihuela,L., Olvera-Rodriguez,A., Rodriguez-Solis,A.M., Borja,M., Garcia-Vazquez,U.O., Jones,J.M., Parkinson,C.L., Alagon,A.. Exploring Venom Diversity in Mixcoatlus browni and Mixcoatlus barbouri: A Comparative Analysis of Two Rare Mexican Snake Species with Crotoxin-like Presence.
Biochimie,
225,
81-88.
Artículo
269 - Olivares-Hernandez,R., Riano-Umbarila,L., Becerril,B., Alagon-Cano,A., Vazquez-Lopez,H.. Pharmacokinetic evaluation of a single chain antibody fragment against scorpion toxins in sheep.
Toxicon,
242,
107691.
Artículo
270 - Valdez-Cruz,N.A., Rosiles-Becerril,D., Martinez-Olivares,C.E., Garcia-Hernandez,E., Cobos-Marin,L., Garzon,D., Lopez-Salas,F.E., Zavala,G., Luviano,A., Olvera,A., Alagon,A., Ramirez,O.T., Trujillo-Roldan,M.A. Oral administration of a recombinant modified RBD antigen of SARS-CoV-2 as a possible immunostimulant for the care of COVID-19.
Microbial Cell Factories,
23 (1),
41.
Artículo
271 - Zarzosa,V., Lomonte,B., Zamudio,F., Ponce-Lopez,R., Olvera-Rodriguez,F., Borja,M., Alagon,A., Neri-Castro,E.. Venom of the neotropical rattlesnake, Crotalus culminatus: Intraspecific variation, neutralization by antivenoms, and immunogenicity in rabbits.
Biochimie,
216,
160-174.
Artículo
272 - Borja,M., Neri-Castro,E., Gutierrez-Martinez,A., Bledsoe,R., Zarzosa,V., Rodriguez-Lopez,B., Strickland,J.L., Becerra-Lopez,J., Valenzuela-Ceballos,S., Parkinson,C.L., Alagon,A., Castaneda-Gaytan,G.. Ontogenetic change in the venom composition of one Mexican black-tailed rattlesnake (Crotalus molossus nigrescens) from Durango, Mexico.
Toxicon,
24,
107280.
Artículo
273 - Perez-Juarez,H., Serrano-Vazquez,A., Godinez-Alvarez,H., Gonzalez,E., Rojas-Velazquez,L., Moran,P., Portillo-Bobadilla,T., Ramiro,M., Hernandez,E., Lau,C., Martinez,M., Padilla,M.L.A., Zaragoza,M.E., Taboada,B., Palomares,L.A., Lopez,S., Alagon,A., Arias,C.F., Ximenez,C.. Longitudinal anti-SARS-CoV-2 antibody immune response in acute and convalescent patients.
Frontiers in Cellular and Infection Microbiology,
13,
1239700.
Artículo
274 - Siegrist,A.A., Boyer,L., Balchan,N.R., Vazquez,H., Alagon,A., de Roodt,A., Craig,I.S., Poulin,I.S., Timmerman,A., Trocola,D.. Outcomes of treatment of snake and scorpion envenomation in birds of prey, with and without antivenom.
Journal of Zoo and Wildlife Medicine,
53 (4),
870-881.
Nacional divulgacion
275 - Alagon Cano,A.. Antivenenos contra animales ponzoñosos: una historia de aventuras científicas y de éxitos para México.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
9 (32).
Artículo
276 - Colis-Torres,A., Neri-Castro,E., Strickland,J.L., Olvera-Rodriguez,A., Borja,M., Calvete,J., Jones,J., Parkinson,C.L., Banuelos,J., Lopez de Leon,J., Alagon,A.. Intraspecific venom variation of Mexican West Coast Rattlesnakes (Crotalus basiliscus) and its implications for antivenom production.
Biochimie,
192,
114-124.
Artículo
277 - Neri-Castro,E., Strickland,J.L., Carbajal-Marquez,R.A., Zuniga,J., Ponce-Lopez,R., Olvera,F., Alagon,A.. Characterization of the venom and external morphology of a natural hybrid between Crotalus atrox and Crotalus mictlantecuhtli.
Toxicon,
207,
43-47.
Artículo
278 - Neri-Castro,E., Zarzosa,V., Colis-Torres,A., Fry,B.G., Olvera-Rodriguez,A., Jones,J., Reyes-Velazquez,J., Zamudio,F., Borja,M., Alagon,A., Lomonte,B.. Proteomic and toxicological characterization of the venoms of the most enigmatic group of rattlesnakes: The long-tailed rattlesnakes.
Biochimie,
202,
226-236.
Artículo
279 - Olvera-Rodriguez,A., Amaro-Ruiz,M.G., Benard-Valle,M., Neri-Castro,E., Olvera-Rodriguez,F., Alagon,A.. Neutralization of black widow spider (Latrodectus mactans) venom with rabbit polyclonal serum hyperimmunized with recombinant alpha-latrotoxin fragments.
Biochimie,
201,
55-62.
Artículo
280 - Youngman,N.J., Carlsson,D.J., Jones,L., Neri-Castro,E., Alagon,A., Fry,B.G.. Cloud serpent coagulotoxicity: The biochemical mechanisms underpinning the anticoagulant actions of Mixcoatlus and Ophryacus venoms.
Toxicon,
211,
44-49.
Nacional Case report
281 - Madrigal-Anaya,J.C., Cruz-Ibarra,A., Rodriguez-Uvalle,N.C., Gil-Alarcon,G., Alagon,A., Rodriguez-Flores,G., Boyer,L., Neri-Castro,E.. A case of exotic envenomation by Naja kaouthia in Mexico.
Latin American Journal of Clinical Sciences and Medical Technology,
4,
1-8.
Artículo
282 - Archundia,I.G., de la Rosa,G., Olvera,F., Calderon,A., Benard-Valle,M., Alagon,A., Corzo,G.. Assessment of neutralization of Micrurus venoms with a blend of anti-Micrurus tener and anti-ScNtx antibodies.
Vaccine,
39 (6),
1000-1006.
Artículo
283 - Benard-Valle, M., Neri-Castro, E., Elizalde-Morales, N., Olvera-Rodriguez, A., Strickland, J., Acosta, G., Alagon, A.. Protein composition and biochemical characterization of venom from Sonoran Coral Snakes (Micruroides euryxanthus).
Biochimie,
182,
206-216.
Artículo
284 - Bourke, L. A., Zdenek, C. N., Neri-Castro, E., Benard-Valle, M., Alagon, A., Gutierrez, J. M., Sanchez, E. F., Aldridge, M., Fry, B. G.. Pan-American Lancehead Pit-Vipers: Coagulotoxic Venom Effects and Antivenom Neutralisation of Bothrops asper and B. atrox Geographical Variants.
Toxins (Basel),
13 (2),
78.
Artículo
285 - Dashevsky,D., Benard-Valle,M., Neri-Castro,E., Youngman,N.J., Zdenek,C.N., Alagon,A., Portes-Junior,J.A., Frank,N., Fry,B.G.. Anticoagulant Micrurus venoms: targets and neutralization.
Toxicology Letters,
337,
91-97.
Artículo
286 - de Roodt,A.R., Lanari,L.C., Ramirez,J.E., Gomez,C., Barragan,J., Litwin,S., van Grootheest,J.H., Desio,M., Dokmetjian,J.C., Dolab,J.A., Damin,C.F., Alagon,A.. Cross-reactivity of some micrurus venoms against experimental and therapeutic anti-micrurus antivenoms.
Toxicon,
200,
153-164.
Artículo
287 - Franco-Servin,C., Neri-Castro,E., Benard-Valle,M., Alagon,A., Rosales-Garcia,R.A., Guerrero-Alba,R., Poblano-Sanchez,J.E., Silva-Briano,M., Guerrero-Barrera,A.L., Sigala-Rodriguez,J.J.. Biological and Biochemical Characterization of Coronado Island Rattlesnake (Crotalus helleri caliginis) Venom and Antivenom Neutralization.
Toxins (Basel),
13 (8),
582.
Artículo
288 - Ponce-Lopez,R., Neri-Castro,E., Olvera-Rodriguez,F., Sanchez,E.E., Alagon,A., Olvera-Rodriguez,A.. Neutralization of crotamine by polyclonal antibodies generated against two whole rattlesnake venoms and a novel recombinant fusion protein.
Toxicon,
197,
70-78.
Artículo
289 - Rodrigues,C.F.B., Zdenek,C.N., Serino-Silva,C., de Morais-Zani,K., Grego,K.F., Benard-Valle,M., Neri-Castro,E., Alagon,A., Tanaka-Azevedo,A.M., Fry,B.G.. Boa g PLI from Boa constrictor Blood is a Broad-Spectrum Inhibitor of Venom PLA(2) Pathophysiological Actions.
Journal of Chemical Ecology,
47,
907-914.
Artículo
290 - Seneci,L., Zdenek,C.N., Chowdhury,A., Rodrigues,C.F.B., Neri-Castro,E., Benard-Valle,M., Alagon,A., Fry,B.G.. A Clot Twist: Extreme Variation in Coagulotoxicity Mechanisms in Mexican Neotropical Rattlesnake Venoms.
Frontiers in Immunology,
12,
612846.
Artículo
291 - Seneci,L., Zdenek,C.N., Bourke,L.A., Cochran,C., Sanchez,E.E., Neri-Castro,E., Benard-Valle,M., Alagon,A., Frank,N., Fry,B.G.. A symphony of destruction: Dynamic differential fibrinogenolytic toxicity by rattlesnake (Crotalus and Sistrurus) venoms.
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology,
245,
109034.
Capítulo nacional
292 - Nares-Torices,M.A., Olguin-Sanchez,E., Rodrigues-Alvarez,D., Alagon-Cano,A., Sanchez-Villegas,M.C.S.. Loxoscelismo. Una Mirada a la Toxinologia de Mexico.
35-58,
Ciudad de Mexico: Cognitio Journal.
Capítulo internacional
293 - Neri-Castro,E., Benard-Valle,M., Lopez de Leon,J., Boyer,L., Alagon,A.. Envenomations by Reptiles in Mexico. Handbook of Venoms and Toxins of Reptiles 2a.
529-542,
2a.
Nacional
294 - Neri-Castro,E., Reyna,M.A., Alagon-Cano,A.. Serpientes Venenosas. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
384-396,
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Nacional
295 - Reyna-Rojas,M.A., Neri-Castro,E.E., Alagon-Cano,A.. Uso, manejo y percepción de herpetofauna en dos localidades del municipio de Tlaltizap án. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
398-411,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
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296 - Neri-Castro,E., Alagon-Cano,A.. Descubrimientos recientes: Venenos de serpientes.
Hypatia,
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298 - Benard-Valle,M., Neri-Castro,E.E., Yanez-Mendoza,M.F., Lomonte,B., Olvera,A., Zamudio,F., Restano-Cassulini,R., Possani,L.D., Jimenez-Ferrer,E., Alagon,A.. Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: Identification of the first lethal multimeric neurotoxin in coral snake venom.
Journal of Proteomics,
225,
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299 - Braga,J.R.M., Jorge,A.R.C., Marinho,A.D., de Moraes Silveira,J.A., Nogueira-Junior,F.A., Benard-Valle,M., Alagon,A., de Menezes,R.R.P.P., Martins,A.M.C., Feijao,L.X., Monteiro,H.S.A., Jorge,R.J.B.. Renal effects of venoms of Mexican coral snakes Micrurus browni and Micrurus laticollaris.
Toxicon,
181,
45-52.
Artículo
300 - Chippaux,J.P., Celis,A., Boyer,L., Alagon,A.. Factors involved in the resilience of incidence and decrease of mortality from scorpion stings in Mexico.
Toxicon,
188,
65-75.
Artículo
301 - Garcia-Osorio,B., Lomonte,B., Benard-Valle,M., Lopez de Leon J., Roman-Dominguez,L., Mejia-Dominguez,N., Lara-Hernandez,F., Alagon,A., Neri-Castro,E.. Ontogenetic changes in the venom of Metlapilcoatlus nummifer, the Mexican jumping viper.
Toxicon,
184,
204-214.
Artículo
302 - Grashof,D., Zdenek,C.N., Dobson,J.S., Youngman,N.J., Coimbra,F., Benard-Valle,M., Alagon,A., Fry,B.G.. A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms.
Toxins (Basel),
12 (2).
Artículo
303 - Neri-Castro,E., Sanz,L., Olvera-Rodriguez,A., Benard-Valle,M., Alagon,A., Calvete,J.J.. Venomics and biochemical analysis of the black-tailed horned pitviper, Mixcoatlus melanurus, and characterization of Melanurutoxin, a novel crotoxin homolog.
Journal of Proteomics,
225,
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304 - Neri-Castro,E., Benard-Valle,M., Paniagua,D., Boyer,L.V., Possani,D., Lopez-Casillas,F., Olvera,A., Romero,C., Zamudio,F., Alagon,A.. Neotropical Rattlesnake (Crotalus simus) Venom Pharmacokinetics in Lymph and Blood Using an Ovine Model.
Toxins (Basel),
12 (7),
455.
Artículo
305 - Paniagua,D., Crowns,K., Montonera,M., Wertheimer,A., Alagon,A., Boyer,L.. Postmortem histopathology and detection of venom by ELISA following suicide by cobra (Naja kaouthia) envenomation.
Forensic Toxicology,
38 (2),
523-528.
Artículo
306 - Ponce-Lopez,R., Neri-Castro,E., Borja,M., Strickland,J.L., Alagon,A.. Neutralizing potency and immunochemical evaluation of an anti-Crotalus mictlantecuhtli experimental serum.
Toxicon,
187,
171-180.
Artículo
307 - Rivas-Mercado E., Neri-Castro E., Benard-Valle M., Rucavado-Romero,A., Olvera-Rodriguez A., Zamudio-Zuniga F., Alagon,A., Garza-Ocanas L.. Disintegrins extracted from totonacan rattlesnake (Crotalus totonacus) venom and their anti-adhesive and anti-migration effects on MDA-MB-231 and HMEC-1 cells.
Toxicology in Vitro,
65,
104809.
Artículo
308 - Sanchez,M., Solano,G., Vargas,M., Reta-Mares,F., Neri-Castro,E., Alagon,A., Sanchez,A., Villalta,M., Leon,G., Segura,A.. Toxicological profile of medically relevant Crotalus species from Mexico and their neutralization by a Crotalus basiliscus/Bothrops asper antivenom.
Toxicon,
179,
92-100.
Nacional
309 - Neri-Castro,E.E., Alagon-Cano,A.. Reptiles venenosos: veneno y tratamiento. Biodiversidad en Morelos. Estudio de estado 2, vol 2.
306-310,
2,
Mexico: CONABIO.
Nacional Editorial
310 - Neri-Castro,E.E., Benard-Valle,M., Gil,J., Lopez de Leon J., Borja,M., Alagon,A.. Serpientes venenosas en México: una revisión al estudio de los venenos, los antivenenos y la epidemiología .
Revista Latinoamericana de Herpetologia,
3 (2),
5-22.
Artículo
311 - de la Rosa,G., Olvera,F., Archundia,I.G., Lomonte,B., Alagon,A., Corzo,G.. Horse immunization with short-chain consensus a-neurotoxin generates antibodies against broad spectrum of elapid venomous species.
Nature Communications,
10 (1),
3642.
Artículo
312 - Kakumanu,R., Hodgson,W.C., Ravi,R., Alagon,A., Harris,R.J., Brust,A., Alewood,P.F., Kemp-Harper,B.K., Fry,B.G.. Vampire Venom: Vasodilatory Mechanisms of Vampire Bat (Desmodus rotundus) Blood Feeding.
Toxins (Basel),
11 (1),
26.
Artículo
313 - Neri-Castro, E., Lomonte, B., Valdes, M., Ponce-Lopez, R., Benard-Valle, M., Borja, M., Strickland, J. L., Jones, J. M., Grunwald, C., Zamudio, F., Alagon, A.. Venom characterization of the three species of Ophryacus and proteomic profiling of O. sphenophrys unveils Sphenotoxin, a novel Crotoxin-like heterodimeric beta-neurotoxin.
Journal of Proteomics,
192,
196-207.
Artículo
314 - Neri-Castro,E., Hernandez-Davila,A., Olvera-Rodriguez,A., Cardoso-Torres,H., Benard-Valle,M., Bastiaans,E., Lopez-Gutierrez,O., Alagon,A.. Detection and quantification of a á-neurotoxin (crotoxin homologs) in the venom of the rattlesnakes Crotalus simus, C. culminatus and C. tzabcan from Mexico.
Toxicon X,
2,
100007.
Artículo
315 - Paniagua,D., Vergara,I., Roman,R., Romero,C., Benard-Valle,M., Calderon,A., Jimenez,L., Bernas,M.J., Witte,M.H., Boyer,L.V., Alagon,A.. Antivenom effect on lymphatic absorption and pharmacokinetics of coral snake venom using a large animal model.
Clinical Toxicology,
57 (8),
727-734.
Artículo
316 - Roman-Dominguez,L., Neri-Castro,E., Vazquez-Lopez,H., Garcia-Osorio,B., Archundia,I.G., Ortiz-Medina,J.A., Petricevich,V.L., Alagon,A., Benard-Valle,M.. Biochemical and immunochemical characterization of venoms from snakes of the genus Agkistrodon.
Toxicon X,
4,
100013.
Nacional
317 - Alagon,A.. Biotecnología de antivenenos mexicana. Manos que sanan. Avances en la medicina potosina.
185-187,
San Luis Potosí, México: Graphstyle Publishers.
Preprint
318 - Montes-Grajales,D., Jimenez,B., Rogel,M.A., Alagon,A., Esturau-Escofet,N., Esquivel,B., Martinez-Romero,J., Martinez-Romero,E.. Nitrogen-fixing Klebsiella variicola in feces from herbivorous tortoises.
bioRxiv,
Preprint posted June 10, 2019,
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Artículo
319 - Borja, M., Neri-Castro, E., Castaneda-Gaytan, G., Strickland, J.L., Parkinson, C.L., Castaneda-Gaytan, J., Ponce-Lopez, R., Lomonte, B., Olvera-Rodriguez, A., Alagon, A., Perez-Morales, R.. Biological and Proteolytic Variation in the Venom of Crotalus scutulatus scutulatus from Mexico.
Toxins (Basel),
10 (1),
35.
Artículo
320 - Borja,M., Neri-Castro,E., Perez-Morales,R., Strickland,J.L., Ponce-Lopez,R., Parkinson,C.L., Espinosa-Fematt,J., Saenz-Mata,J., Flores-Martinez,E., Alagon,A., Castaneda-Gaytan,G.. Ontogenetic Change in the Venom of Mexican Black-Tailed Rattlesnakes (Crotalus molossus nigrescens).
Toxins (Basel),
10 (12).
Artículo
321 - Calcines-Cruz, C., Olvera, A., Castro-Acosta, R.M., Zavala, G., Alagon, A., Trujillo-Roldan, M.A., Valdez-Cruz, N.A.. Recombinant-phospholipase A2 production and architecture of inclusion bodies are affected by pH in Escherichia coli.
International Journal of Biological Macromolecules,
108,
826-836.
Artículo
322 - Dobson, J., Yang, D., Op den, Brouw B., Cochran, C., Huynh, T., Kurrupu, S., Sanchez, E.E., Massey, D.J., Baumann, K., Jackson, T.N.W., Nouwens, A., Josh, P., Neri-Castro, E., Alagon, A., Hodgson, W.C., Fry, B.G.. Rattling the border wall: Pathophysiological implications of functional and proteomic venom variation between Mexican and US subspecies of the desert rattlesnake Crotalus scutulatus.
Comparative Biochemistry and Physiology C Toxicology and Pharmacology,
205,
62-69.
Artículo
323 - Guerrero-Garzon, J.F., Benard-Valle, M., Restano-Cassulini, R., Zamudio, F., Corzo, G., Alagon, A., Olvera-Rodriguez, A.. Cloning and sequencing of three-finger toxins from the venom glands of four Micrurus species from Mexico and heterologous expression of an alpha-neurotoxin from Micrurus diastema.
Biochimie,
147,
114-121.
Artículo
324 - de la Rosa G., Pastor, N., Alagon, A., Corzo, G.. Synthetic peptide antigens derived from long-chain alpha-neurotoxins: Immunogenicity effect against elapid venoms.
Peptides,
88,
80-86.
Artículo
325 - Durban, J., Sanz, L., Trevisan-Silva, D., Neri-Castro, E., Alagon, A., Calvete, J.J.. Integrated venomics and venom gland transcriptome analysis of juvenile and adult Mexican rattlesnakes Crotalus simus, C. tzabcan and C. culminatus revealed miRNA-modulated ontogenetic shifts.
Journal of Proteome Research,
16 (9),
3370-3390.
Artículo
326 - Hernandez-Vargas, M.J., Gil, J., Lozano, L., Pedraza-Escalona, M., Ortiz, E., Encarnacion-Guevara, S., Alagon, A., Corzo, G.. Proteomic and transcriptomic analysis of saliva components from the hematophagous reduviid Triatoma pallidipennis.
Journal of Proteomics,
162,
30-39.
Artículo
327 - Rivas, E., Neri-Castro, E., Benard-Valle, M., Hernandez-Davila, A.I., Zamudio, F., Alagon, A.. General characterization of the venoms from two species of rattlesnakes and an intergrade population (C. lepidus x aquilus) from Aguascalientes and Zacatecas, Mexico.
Toxicon,
138,
191-195.
Artículo
328 - Valdez-Cruz, N.A., Reynoso-Cereceda, G.I., Perez-Rodriguez, S., Restrepo-Pineda, S., Gonzalez-Santana, J., Olvera, A., Zavala, G., Alagon, A., Trujillo-Roldan, M.A.. Production of a recombinant phospholipase A2 in Escherichia coli using resonant acoustic mixing that improves oxygen transfer in shake flasks.
Microbial Cell Factories,
16 (1),
129.
Artículo
329 - Yang, D.C., Dobson, J., Cochran, C., Dashevsky, D., Arbuckle, K., Benard, M., Boyer, L., Alagon, A., Hendrikx, I., Hodgson, W.C., Fry, B.G.. The Bold and the Beautiful: a Neurotoxicity Comparison of New World Coral Snakes in the Micruroides and Micrurus Genera and Relative Neutralization by Antivenom.
Neurotoxicity Research,
32 (3),
487-495.
Internacional
330 - Paniagua, D., Vergara, I., Boyer, L., Alagon, A.. Role of Lymphatic System on Snake Venom Absorption. Snake Venoms. Toxicology Series.
453-474,
Dordrecht.
Artículo
331 - Clement,H., Flores,V., de la Rosa,G., Zamudio,F., Alagon,A., Corzo,G.. Heterologous expression, protein folding and antibody recognition of a neurotoxin from the Mexican coral snake Micrurus laticorallis.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
22 (1),
25.
Revisión
332 - Lomonte,B., Rey-Suarez,P., Fernandez,J., Sasa,M., Pla,D., Vargas,N., Benard-Valle,M., Sanz,L., Correa-Netto,C., Nunez,V., Alape-Giron,A., Alagon,A., Gutierrez,J.M., Calvete,J.J.. Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses.
Toxicon,
122,
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Artículo
333 - Olvera,F., Rosales,A., Olvera,A., Diaz,P., Sevcik,C., Salazar,V., Alagon,A., Hernandez,H., D'Suze,G.. An efficient approach to clone and express active Neopladine 2, an anticancer peptide from Tityus discrepans scorpion venom.
Process Biochemistry,
51 (5),
624-631.
Artículo
334 - Vergara,I., Castillo,E.Y., Romero-Pina,M.E., Torres-Viquez,I., Paniagua,D., Boyer,L.V., Alagon,A., Medina,L.A.. Biodistribution and Lymphatic Tracking of the Main Neurotoxin of Micrurus fulvius Venom by Molecular Imaging.
Toxins (Basel),
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Artículo
335 - Bush,S.P., Ruha,A.M., Seifert,S.A., Morgan,D.L., Lewis,B.J., Arnold,T.C., Clark,R.F., Meggs,W.J., Toschlog,E.A., Borron,S.W., Figge,G.R., Sollee,D.R., Shirazi,F.M., Wolk,R., de Chazal,I, Quan,D., Garcia-Ubbelohde,W., Alagon,A., Gerkin,R.D., Boyer,L.V.. Comparison of F(ab') versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial.
Clinical Toxicology,
53 (1),
37-45.
Revisión
336 - Chippaux,J.P., Boyer,L.V., Alagon,A.. Post-exposure treatment of Ebola virus using passive immunotherapy: proposal for a new strategy.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
21,
3,
3.
Internacional
337 - Benard-Valle,M., Neri,E., Fry,B., Boyer,L., Cochran,C., Alam,M., Jackson,T.N.W., Paniagua,D., Sheira,D., Olvera-Rodriguez,F., Koludorov,I., Sunagar,K., Alagon,A.. Antivenom research and development. Venomous reptiles and their toxins: Evolution, pathophysiology and biodiscovery .
61-72,
New York.
Internacional
338 - Boyer,L., Alagon,A., Fry,B.G., Jackson,T.N.W., Sunagar,K., Chippaux,J.P.. Signs, symptoms and treatment of envenomation. Venomous Reptiles and Their Toxins: Evolution, Pathophysiology and Biodiscovery.
32-60,
New York: Oxford University Press.
Internacional
339 - Paniagua,D., Vergara,I., Boyer,L., Alagon,A.. Role of Lymphatic System on Snake Venom Absorption. Snake Venoms.
Toxinology,
1-19.
Divulgación
340 - Reyna-Rojas,M.A., Garcia-Flores,A., Neri-Castro,E., Alagon-Cano,A., Monroy-Martinez,R.. Conocimiento etnoherpetológico de dos comunidades aledañas a la reserva estatal sierra de montenegro, Morelos, Mexico.
Etnobiologia,
13 (2),
37-48.
Artículo
341 - Benard-Valle,M., Carbajal-Saucedo,A., de Roodt,A., Lopez-Vera,E., Alagon,A.. Biochemical characterization of the venom of the coral snake Micrurus tener and comparative biological activities in the mouse and a reptile model.
Toxicon,
77,
6-15.
Artículo
342 - Borja,M., Castaneda,G., Espinosa,J., Neri,E., Carbajal,A., Clement,H., Garcia,O., Alagon,A.. Mojave Rattlesnake (Crotalus scutulatus scutulatus) with Type B Venom from Mexico.
Copeia,
2014 (1),
7-13.
Artículo
343 - Carbajal-Saucedo,A., Floriano,R.S., Belo,C.A., Olvera-Rodriguez,A., Alagon,A., Rodrigues-Simioni,L.. Neuromuscular Activity of Micrurus laticollaris (Squamata: Elapidae) Venom in Vitro.
Toxins (Basel),
6 (1),
359-370.
Artículo
344 - Castellanos-Mendoza,A., Castro-Acosta,R.M., Olvera,A., Zavala,G., Mendoza-Vera,M., Garcia-Hernandez,E., Alagon,A., Trujillo-Roldan,M.A., Valdez-Cruz,N.A.. Influence of pH control in the formation of inclusion bodies during production of recombinant sphingomyelinase-D in Escherichia coli.
Microbial Cell Factories,
13 (1),
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Artículo
345 - de Roodt,A.R., Clement,H., Dolab,J.A., Litwin,S., Hajos,S.E., Boyer,L., Alagon,A.. Protein content of antivenoms and relationship with their immunochemical reactivity and neutralization assays.
Clinical Toxicology,
52 (6),
594-603.
Artículo
346 - Diaz,P., Malave,C., Zerpa,N., Vazquez,H., D'Suze,G., Montero,Y., Castillo,C., Alagon,A., Sevcik,C.. IgY pharmacokinetics in rabbits: Implications for IgY use as antivenoms.
Toxicon,
90,
124-133.
Artículo
347 - Lanari,L.C., Olvera,A., Costa de Oliveira,V, Laskowicz,R.D., Boyer,L., Lago,N.R., Alagon,A., de Roodt,A.R.. Intraspecific differences in the immunochemical reactivity and neutralization of venom from Argentinean Bothrops (Rhinocerophis) alternatus by specific experimental antivenoms.
Toxicon,
85,
31-45 [corrigendum vol 88 p 138].
Artículo
348 - Sanchez-Villegas,M del C., Rodriguez-Alvarez,D., Ortega-Carrillo,C., Alagon-Cano,A., Zaldivar-Cervera,J., Loria-Castellanos,J., Urzua-Rodríguez,N.A.. [Systemic loxoscelism presented in a pregnant patient].
Revista Médica del Instituto Mexicano del Seguro Social,
52 (1),
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Artículo
349 - Sanchez-Villegas,M del C., Nazario-Santiago,C., Alagon-Cano,A., Merquez-Avila,G., Ramos-Cervantes,M.T., Loria-Castellanos,J.. Cunico-epidemiological characteristics of pediatric patients with poisoning by loxosceles spiders bite.
Prensa Medica Argentina,
100 (9),
605-613.
Artículo
350 - Vergara,I., Pedraza-Escalona,M., Paniagua,D., Restano-Cassulini,R., Zamudio,F., Batista,C.V., Possani,L.D., Alagon,A.. Eastern coral snake Micrurus fulvius venom toxicity in mice is mainly determined by neurotoxic phospholipases A.
Journal of Proteomics,
105,
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Divulgación
351 - Corzo-Burguete,G., Alagon-Cano,A., Clement-Carretero,H., Jurado-Reyes,S.M., Herrera-Herrera,E.. Los venenos de tar ntulas y la absorción de medicinas en nuestro cuerpo.
Hypatia,
48 (2).
Divulgación
352 - Neri-Castro,E., Benard-Valle,M., Alagon-Cano,A.. Reptiles venenosos en M?xico.
Revista Digital Universitaria,
15 (11),
art 86.
Artículo
353 - Boyer,L., Degan,J., Ruha,A.M., Mallie,J., Mangin,E., Alagon,A.. Safety of Intravenous Equine F(ab'): Insights following Clinical Trials involving 1534 Recipients of Scorpion Antivenom.
Toxicon,
76,
386-393.
Artículo
354 - Boyer,L.V., Chase,P.B., Degan,J.A., Figge,G., Buelna-Romero,A., Luchetti,C., Alagon,A.. Subacute coagulopathy in a randomized, comparative trial of Fab and F(ab') antivenoms.
Toxicon,
74,
101-108.
Artículo
355 - Boyer,L.V., Theodorou,A.T., Chase,P.B., Osnaya,N., Berg,M., Mallie,J., Carbajal,Y., de Jesus-Hernandez,T., Olvera,F., Alagon,A.. Effectiveness of Centruroides scorpion antivenom compared to historical controls.
Toxicon,
76,
377-385.
Artículo
356 - Low,D.H., Sunagar,K., Undheim,E.A., Ali,S.A., Alagon,A.C., Ruder,T., Jackson,T.N., Pineda-Gonzalez,S., King,G.F., Jones,A., Antunes,A., Fry,B.G.. Dracula's children: Molecular evolution of vampire bat venom.
Journal of Proteomics,
89C,
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Artículo
357 - Neri-Castro,E., Lomonte,B., Gutierrez,M.C., Alagon,A., Gutierrez,J.M.. Intraspecies variation in the venom of the rattlesnake Crotalus simus from Mexico: Different expression of crotoxin results in highly variable toxicity in the venoms of three subspecies.
Journal of Proteomics,
87,
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358 - Oukkache,N., Chgoury,F., Lalaoui,M., Alagon-Cano,A., Ghalim,N.. Comparison between two methods of scorpion venom milking in Morocco.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
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359 - Vazquez,H., Olvera,F., Alagon,A., Sevcik,C.. Production of anti-horse antibodies induced by IgG, F(ab') and Fab applied repeatedly to rabbits. Effect on antivenom pharmacokinetics.
Toxicon,
76,
362-369.
Divulgación
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361 - Clement,H., Olvera,A., Rodriguez,M., Zamudio,F., Palomares,L.A., Possani,L.D., Odell,G.V., Alagon,A., Sanchez-Lopez,R.. Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom.
Toxicon,
60 (7),
1223-1227.
Artículo
362 - Clement,H., Costa de Oliveira,V, Zamudio,F.Z., Lago,N.R., Valdez-Cruz,N.A., Valle,M.B., Alagon,A.C., Possani,L.D., de Roodt,A.R.. Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A(2) from Bothrops (Rhinocerophis) ammodytoides Venom.
Toxicon,
60 (7),
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Artículo
363 - Koludarov,I., Sunagar,K., Undheim,E.A., Jackson,T.N., Ruder,T., Whitehead,D., Saucedo,A.C., Mora,G.R., Alagon,A.C., King,G., Antunes,A., Fry,B.G.. Structural and Molecular Diversification of the Anguimorpha Lizard Mandibular Venom Gland System in the Arboreal Species Abronia graminea.
Journal of Molecular Evolution,
75 (5-6),
168-183.
Artículo
364 - Paniagua,D., Jimenez,L., Romero,C., Vergara,I., Calderon,A., Benard,M., Bernas,M.J., Rilo,H., de Roodt,A., D'Suze,G., Witte,M.H., Boyer,L., Alagon,A.. Lymphatic route of transport and pharmacokinetics of Micrurus fulvius (coral snake) venom in sheep.
Lymphology,
45 (4),
144-153.
Artículo
365 - Archundia,I.G., de Roodt,A.R., Ramos-Cerrillo,B., Chippaux,J.P., Olguin-Perez,L., Alagon,A., Stock,R.P.. Neutralization of Vipera and Macrovipera venoms by two experimental polyvalent antisera: A study of paraspecificity.
Toxicon,
57 (7-8),
1049-1056.
Nacional
366 - Alagon,A., Odell,G.. La biologia y taxonomia de las aranas americanas. Emergencias por Animales Ponzonosos en las Americas .
181-201,
Mexico: Instituto Bioclon & Laboratorios Silanes.
Artículo
367 - Redaelli,E., Restano-Cassulini,R., Fuentes-Silva,D., Clement,H., Schiavon,E., Zamudio,F.Z., Odell,G., Arcangeli,A., Clare,J.J., Alagon,A., Rodriguez de la Vega,R.C., Possani,L.D., Wanke,E.. Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.
Journal of Biological Chemistry,
285 (6),
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368 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics of a F(ab')(2) scorpion antivenom administered intramuscularly in healthy human volunteers.
International Immunopharmacology,
10 (11),
1318-1324.
Artículo
369 - Vazquez,H., Olvera,F., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics in rabbits and anti-sphingomyelinase D neutralizing power of Fab, F(ab')2, IgG and IgG(T) fragments from hyper immune equine plasma.
International Immunopharmacology,
10 (4),
447-454.
Divulgación
370 - Alagon-Cano,A., Corzo,G., Clement-Carretero,H., Garcia-Garcia,F.. Arañas: venenos con potencial biotecnológico.
Hypatia,
33.
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371 - Boyer,L.V., Theodorou,A.A., Berg,R.A., Mallie,J., Chavez-Mendez,A., Garcia-Ubbelohde,W., Hardiman,S., Alagon,A.. Antivenom for critically ill children with neurotoxicity from scorpion stings.
New England Journal of Medicine,
360 (20),
2090-2098 (Reply 2009 vol 361 632).
Artículo
372 - Casasola,A., Ramos-Cerrillo,B., de Roodt,A.R., Saucedo,A.C., Chippaux,J.P., Alagon,A., Stock,R.P.. Paraspecific neutralization of the venom of African species of cobra by an equine antiserum against Naja melanoleuca: A comparative study.
Toxicon,
53 (6),
602-608.
Artículo
373 - Chase,P., Boyer-Hassen,L., McNally,J., Vazquez,H.L., Theodorou,A.A., Walter,F.G., Alagon,A.. Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients.
Clinical Toxicology,
47 (1),
24-28.
Artículo
374 - Corzo,G., Bernard,C., Clement,H., Villegas,E., Bosmans,F., Tytgat,J., Possani,L.D., Darbon,H., Alagon,A.. Insecticidal peptides from the theraposid spider Brachypelma albiceps: A NMR-based model of Ba2.
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics,
1794 (8),
1190-1196.
Divulgación
375 - Rodriguez,M., Prud`Homme,M., Alagon,A., Stock,R.. Expresión de a-latrotoxina Recombinante Activa de Latrodectus mactans Utilizando el Sistema de Células de Insecto-Baculovirus.
BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria,
13 (2),
34-47.
Artículo
376 - Chippaux,J.P., Alagon,A.. [Envenomation and poisoning by venomous or poisonous animals. VII: arachnidism in the New World].
Medecine Tropicale,
68 (3),
215-221.
Artículo
377 - Corzo,G., Diego-Garcia,E., Clement,H., Peigneur,S., Odell,G., Tytgat,J., Possani,L.D., Alagon,A.. An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.
Peptides,
29 (11),
1901-1908.
Artículo
378 - Ramos-Cerrillo,B., de Roodt,A.R., Chippaux,J.P., Olguin,L., Casasola,A., Guzman,G., Paniagua-Solis,J., Alagon,A., Stock,R.P.. Characterization of a new polyvalent antivenom (Antivipmyn((R)) Africa) against African vipers and elapids.
Toxicon,
52 (8),
881-888.
Nacional
379 - Mata-Gonzalez,M.T., Garcia-Ubbelohde,W., Alagon-Cano,A., Paniagua-Solis,J.. Anticuerpos monoclonales para uso terap?utico en humanos.
Informaceutico Mexico,
15 (9-10),
30-36.
Nacional
380 - Rendon-Anaya,M., Alagon,A.. Mecanismos moleculares de diversificación de inmunoglobulinas.
Revista de Educación Bioquímica,
27 (1),
19-29.
Artículo
381 - Chippaux,J.P., Massougbodji,A., Stock,R.P., Alagon,A.. Clinical Trial of an F(ab')2 Polyvalent Equine Antivenom for African Snake Bites in Benin.
American Journal of Tropical Medicine and Hygiene,
77 (3),
538-546.
Artículo
382 - Clement,H., Odell,G., Zamudio,F.Z., Redaelli,E., Wanke,E., Alagon,A., Possani,L.D.. Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels.
Toxicon,
50 (1),
65-74.
Artículo
383 - de Roodt,A.R., Estevez-Ramirez,J., Litwin,S., Magana,P., Olvera,A., Alagon,A.. Toxicity of two North American Loxosceles (brown recluse spiders) venoms and their neutralization by antivenoms.
Clinical Toxicology,
45 (6),
678-687.
Carta
384 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R., Algaron,A., Fox,J.W.. Upregulation of IL-6, IL-8, CXCL1, and CXCL2 Dominates Gene Expression in Human Fibroblast Cells Exposed to Loxosceles reclusa Sphingomyelinase D: Insights into Spider Venom Dermonecrosis.
Journal of Investigative Dermatology,
127 (5),
1264-1266.
Carta
385 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R.P., Alagon,A., Fox,J.W.. Upregulation of cytokine expression in fibroblasts exposed to Loxosceles sphingomyelinase D: What is the trigger? - Response to Moolenaar et al.
Journal of Investigative Dermatology,
127 (5),
1267-1268.
Artículo
386 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Alagon,A.. Antigenic cross-reactivity between sixteen venoms from scorpions belonging to six genera.
Clinical Toxicology,
45 (2),
158-163.
Biographical-Item
387 - Alagon,A., Clement-Carretero,H., Lomonte,B., Gutierrez,J.M., Ownby,C.L.. Obituary of George V. Odell, 1926-2006.
Toxicon,
49 (6),
886-887.
Divulgación
388 - Olvera-Rodriguez,A., Alagon-Cano,A., Ramos-Cerrillo,B., Cardoso-Torres,H.M., Olvera-Rodriguez,F.. La partitura de la araña violinista: Envenenamiento fatal.
Hypatia,
22.
Editorial Material
389 - Stock,R.P., Massougbodji,A., Alagon,A., Chippaux,J.P.. Bringing antivenoms to Sub-Saharan Africa.
Nature Biotechnology,
25 (2),
173-177.
Artículo
390 - Almagro,J.C., Martinez,L., Smith,S.L., Alagon,A., Estevez,J., Paniagua,J.. Analysis of the horse V(H) repertoire and comparison with the human IGHV germline genes, and sheep, cattle and pig V(H) sequences.
Molecular Immunology,
43 (11),
1836-1845.
Artículo
391 - Olvera,A., Ramos-Cerrillo,B., Estevez,J., Clement,H., de Roodt,A., Paniagua-Solis,J., Vazquez,H., Zavaleta,A., Salas-Arruz,M., Stock,R.P., Alagon,A.. North and South American Loxosceles spiders: Development of a polyvalent antivenom with recombinant sphingomyelinases D as antigens.
Toxicon,
48 (1),
64-74.
Artículo
392 - de Roodt,A.R., Estevez-Ramirez,J., Paniagua-Solis,J.F., Litwin,S., Carvajal-Saucedo,A., Dolab,J.A., Robles-Ortiz,L.E., Alagon,A.. [Toxicity of venoms from snakes of medical importance in Mexico].
Gaceta Medica de Mexico,
141 (1),
13-21.
Artículo
393 - de Roodt,A.R., Salomon,O.D., Orduna,T.A., Robles-Ortiz,L.E., Paniagua-Solis,J.F., Cano,A.A.. Poisoning by bee sting.
Gaceta Medica de Mexico,
141 (3),
215-222.
Artículo
394 - Ramos,M.A., Sanchez-Lopez,R., Mares,R.E., Olvera,F., Alagon,A.. Identification of an Entamoeba histolytica gene encoding a protein disulfide isomerase that functionally complements the dsbA mutation in Escherichia coli.
Molecular and Biochemical Parasitology,
143 (2),
236-240.
Artículo
395 - Sadurni,P., Alagon,A., Aliev,R., Burillo,G., Hoffman,A.S.. Immobilization of streptavidin-horseradish peroxidase onto a biotinylated poly(acrylic acid) backbone that had been radiation-grafted to a PTFE film.
Journal of Biomaterials Science-Polymer Edition,
16 (2),
181-187.
Artículo
396 - Salgado,M., Villagomez-Castro,J.C., Rocha-Rodriguez,R., Sabanero-Lopez,M., Ramos,M.A., Alagon,A., Lopez-Romero,E., Sanchez-Lopez,R.. Entamoeba histolytica: Biochemical and molecular insights into the activities within microsomal fractions.
Experimental Parasitology,
110 (4),
363-373.
Artículo
397 - Sanchez,R., Saralegui,A., Olivos-Garcia,A., Scapolla,C., Damonte,G., Sanchez-Lopez,R., Alagon,A., Stock,R.P.. Entamoeba histolytica: intracellular distribution of the sec61alpha subunit of the secretory pathway and down-regulation by antisense peptide nucleic acids.
Experimental Parasitology,
109 (4),
241-251.
Artículo
398 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Mancilla-Nava,R., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics of a F(ab')(2) scorpion antivenom in healthy human volunteers.
Toxicon,
46 (7),
797-805.
News Item
399 - Chippaux,J.P., Stock,R.P., Alagon,A.. Report of the 2nd international conference on envenomations in Africa (Deuxieme colloque international sur les envenomations en Afrique).
Toxicon,
46 (1),
115-118.
Artículo
400 - de Roodt,A.R., Paniagua-Solis,J.F., Dolab,J.A., Estevez-Ramirez,J., Ramos-Cerrillo,B., Litwin,S., Dokmetjian,J.C., Alagon,A.. Effectiveness of two common antivenoms for North, Central, and South American Micrurus envenomations.
Journal of Toxicology - Clinical Toxicology,
42 (2),
171-178.
Artículo
401 - Ramos-Cerrillo,B., Olvera,A., Odell,G.V., Zamudio,F., Paniagua-Solis,J., Alagon,A., Stock,R.P.. Genetic and enzymatic characterization of sphingomyelinase D isoforms from the North American fiddleback spiders Loxosceles boneti and Loxosceles reclusa.
Toxicon,
44 (5),
507-514 .
Divulgación
402 - Alagon,A., Odell,G.. Acroceroide parasitism of the Mexican tarantula Aphonopelma duplex.
Forum Magazine.American Tarantula Society,
13,
57-58.
Divulgación
Artículo
404 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Aguilar,V., Alagon,A.. Relationship between plasmatic levels of various cytokines, tumour necrosis factor, enzymes, glucose and venom concentration following Tityus scorpion sting.
Toxicon,
41 (3),
367-375.
Nacional
405 - Alagon,A., Possani,L.D.. Desarrollo de nuevos f rmacos a partir de la fauna tropical. Fronteras de la Biología en los Inicios del Siglo XXI, Módulo VII .
123-160,
Mexico,D.F..
Nacional
406 - Alagon,A., Carillo,C., Chavez-Haro,A., De la Mora-Zerpa,C., Larralde,C., Lamas,N, Martin,E, Osnaya-Romero,N., Perez,Y, Possani,L.D., Romero-Zamora,L.. Práctica Médica Efectiva- Alacranismo (T63.2, X22).
Mexico.
Artículo
407 - Nieto-Sotelo,J., Martinez,L.M., Ponce,G., Cassab,G.I., Alagon,A., Meeley,R.B., Ribaut,J.M., Yang,R.. Maize HSP101 Plays Important Roles in Both Induced and Basal Thermotolerance and Primary Root Growth.
Plant Cell,
14 (7),
1621-1633.
Artículo
408 - Ramos,M.A., Sanchez-Lopez,R., Olvera,F., Alagon,A.. Entamoeba histolytica genomic organization: identification, structure, and phylogenetic relationship of two serine-threonine protein kinases.
Experimental Parasitology,
100 (2),
135-139.
Artículo
409 - Sanchez,R., Alagon,A., Stock,R.P.. Entamoeba histolytica: intracellular distribution of the proteasome.
Experimental Parasitology,
102 (3-4),
187-190.
Divulgación
410 - Alagon,A.. Anticuerpos seguros y eficaces: la revoluacion de los nuevos antivenenos.
Revista Universidad de Mexico,
617.
Divulgación
Artículo
412 - Juarez,P., Sanchez-Lopez,R., Stock,R.P., Olvera,A., Ramos,M.A., Alagon,A.. Characterization of the Ehrab8 gene, a marker of the late stages of the secretory pathway of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
116 (2),
223-228.
Artículo
413 - Stock,R.P., Olvera,A., Sanchez,R., Saralegui,A., Scarfi,S., Sanchez-Lopez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Alagon,A.. Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers.
Nature Biotechnology,
19 (3),
231-234.
Divulgación
414 - Ramos,M.A., Alagon,A.. Ruta secretoria y Entamoeba histolytica.
Mensaje Bioquimico,
25,
111-128.
Artículo
415 - Gutierrez,A., Sanchez-Lopez,R., Ramos,M.A., Alagon,A.. Cloning of the Entamoeba histolytica STT3 gene, a subunit of the oligosaccharyltransferase complex.
Archives of Medical Research,
31 (4 Suppl),
S162-S164.
Artículo
416 - Juarez,P., Sanchez-Lopez,R., Ramos,M.A., Stock,R.P., Alagon,A.. Rab8 as a molecular model of vesicular trafficking to investigate the latter steps of the secretory pathway in Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S157-S159.
Artículo
417 - Ramos,M.A., Alagon,A.. Molecular cloning of a gene encoding a PDI-like protein from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S173-S175.
Artículo
418 - Ramos,M.A., Sanchez-Lopez,R., Alagon,A.. Genomic organization of a 7 Kb gene cluster from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S263-S265.
Artículo
419 - Sanchez-Lopez,R., Gutierrez,A., Juarez,P., Olvera,A., Olvera,F., Ramos,M.A., Sanchez,R., Saralegui,A., Stock,R.P., Alagon,A.. Molecular genetics of the secretory pathway in Entamoeba histolytica: an overview.
Archives of Medical Research,
31 (4 Suppl),
S151-S152.
Artículo
420 - Sanchez-Lopez,R., Siminovich,B., Alagon,A.. Entamoeba histolytica codes for a protein homologue of the Sec61 alpha subunit, a component of the endoplasmic reticulum translocon.
Archives of Medical Research,
31 (4 Suppl),
S168-S170.
Artículo
421 - Stock,R.P., Olvera,A., Scarfi,S., Sanchez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Landt,O., Alagon,A.. Inhibition of neomycin phosphorotransferase expression in Entamoeba histolytica with antisense peptide nucleic acid (PNA) oligomers.
Archives of Medical Research,
31 (4 Suppl),
S271-S272.
Nacional
422 - Estrada-Galvan,B., Scheinvar,L., Alagon,A., Olalde-Parra,G.. Resultados preliminares de electroforesis en proteínas como método auxiliar en la taxonomía de Opuntia spp.
Acta Cientifica Potosina,
15 (1),
7-24.
Artículo
423 - Que,X., Kim,D., Alagon,A., Hirata,K., Shike,H., Shimizu,C., Gonzalez,A., Burns,J.C., Reed,S.L.. Pantropic retroviral vectors mediate gene transfer and expression in Entamoeba histolytica.
Molecular and Biochemical Parasitology,
99 (2),
237-245.
Artículo
424 - Sanchez-Gonzalez,M., Alagon,A., Rodriguez-Sotres,R., Lopez-Munguia,A.. Proteolytic processing of dextransucrase of Leuconostoc mesenteroides.
Fems Microbiology Letters,
181 (1),
25-30.
Artículo
425 - Sanchez-Lopez,R., Gama-Castro,S., Ramos,M.A., Merino,E., Lizardi,P.M., Alagon,A.. Cloning and expression of the Entamoeba histolytica ERD2 gene.
Molecular and Biochemical Parasitology,
92 (2),
355-359.
Artículo
426 - Vargas-Villarreal,J., Olvera-Rodriguez,A., Mata-Cardenas,B.D., Martinez-Rodriguez,H.G., Said-Fernandez,S., Alagon-Cano,A.. Isolation of an Entamoeba histolytica intracellular alkaline phospholipase A(2).
Parasitology Research,
84 (4),
310-314.
Nacional
427 - Estrada,G., Sanchez,R., Lizardi,P.M., Alagon,A.. Entamoeba histolytica y la reaccion en cadena de polimerasa por hibridazion y liberacion enzimatica (PCR-HERA). Biologia molecular en medicina.
Coleccion de textos politecnicos, series biotecnologicas.,
47-60,
Mexico DF.
Artículo; Actas Paper
428 - Olvera,A., Olvera,F., Vines,R.R., Recillas-Targa,F., Lizardi,P.M., Dhar,S., Bhattacharya,S., Petri,W.,Jr, Alagon,A.. Stable transfection of Entamoeba histolytica trophozoites by lipofection.
Archives of Medical Research,
28 . (Spec No:49-51),
49-51.
Artículo
429 - Ramos,M.A., Mercado,G.C., Salgado,L.M., Sanchez-Lopez,R., Stock,R.P., Lizardi,P.M., Alagon,A.. Entamoeba histolytica contains a gene encoding a homologue to the 54 kDa subunit of the signal recognition particle.
Molecular and Biochemical Parasitology,
88 (1-2),
225-235.
Artículo; Actas Paper
430 - Ramos,M.A., Stock,R.P., Lizardi,P.M., Alagon,A.. The secretory pathway of Entamoeba histolytica: characterization and expression of the SRP54 gene.
Archives of Medical Research,
28 (Spec No:56-8.),
56-58.
Artículo
431 - Ramos,M.A., Stock,R.P., Sanchez-Lopez,R., Olvera,F., Lizardi,P.M., Alagon,A.. The Entamoeba histolytica proteasome alpha-subunit gene.
Molecular and Biochemical Parasitology,
84 (1),
131-135.
Artículo; Actas Paper
432 - Sanchez-Lopez,R., Gama-Castro,S., Lizardi,P.M., Alagon,A.. The secretory pathway of Entamoeba histolytica: characterization and expression of the ERD2 gene.
Archives of Medical Research,
28 (Spec No:59-61.),
59-61.
Artículo
433 - Estrada,G., Colin,L., Gaytan,P., Alagon,A., Lizardi,P.M.. Sequence-specific detection of PCR-amplified DNA by restriction enzyme release of hybrids.
Molecular and cellular probes,
10 (3),
179-185.
Artículo
434 - Miranda,R., Salgado,L.M., Sanchez-Lopez,R., Alagon,A., Lizardi,P.M.. Identification and analysis of the u6 small nuclear RNA gene from Entamoeba histolytica.
Gene,
180 (1-2),
37-42.
Artículo
435 - Ortega-Pierres,G., Alagon,A., Cortes,A., Olvera,F., Olvera,A., Gonzalez,A., Lizardi,P., Berzunza-Cruz,M., Saavedra-Lira,E., Perez-Montfort,R., Velasco-Castrejon,O., Sotero-Delgado Dominguez,I., Becker,I., Hernandez,R., Martinez-Calvillo,S., Frixione,E., Ruiz,L., Santillan,M., Vega,L., Tejero,J.M., Undeen,A.H., Kretschmer,R.R., Herion,P., Saavedra,R., Yepez-Mulia,L.. [Impact of new methodologies in the study of parasites].
Gaceta Medica de Mexico,
132 (5),
475-517.
Nacional
Artículo
437 - Michel,B., Lizardi,P.M., Alagon,A., Zurita,M.. Identification and analysis of the start site of ribosomal RNA transcription of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
73 (1-2),
19-30.
Artículo
438 - Noeske-Jungblut,C., Haendler,B., Donner,P., Alagon,A., Possani,L., Schleuning,W.D.. Triabin, a highly potent exosite inhibitor of thrombin.
Journal of Biological Chemistry,
270 (48),
28629-28634.
Internacional
439 - Dehesa-Davila,M., Alagon,A.C., Possani,L.D.. Clinical toxicology of scorpion stings. Handbook of clinical toxicology of animal venoms and poisons.
221-238,
New York.
Artículo
440 - Noeske-Jungblut,C., Kratzschmar,J., Haendler,B., Alagon,A., Possani,L., Verhallen,P., Donner,P., Schleuning,W.D.. An inhibitor of collagen-induced platelet aggregation from the saliva of Triatoma pallidipennis.
Journal of Biological Chemistry,
269 (7),
5050-5053.
Artículo
441 - Palmeros,B., Guereca,L., Alagon,A., Soberon-Chavez,G.. Biochemical characterization of the lipolytic activity of pseudomonas aeruginosa IGB 83.
Process Biochemistry,
29 (3),
207-212.
Artículo
442 - Cevallos,M.A., Porta,H., Alagon,A.C., Lizardi,P.M.. Sequence of the 5.8S ribosomal gene of pathogenic and non-pathogenic isolates of Entamoeba histolytica.
Nucleic Acids Research,
21 (2),
355-355.
Note
443 - Cevallos,M.A., Navarro-Duque,C., Varela-Julia,M., Alagon,A.C.. Molecular mass determination and assay of venom hyaluronidases by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Toxicon,
30 (8),
925-930.
Note
444 - Michel,B., Alagon,A., Lizardi,P.M., Zurita,M.. Characterization of a repetitive DNA element from Entamoeba histolytica.
Molecular and Biochemical Parasitology,
51 (1),
165-168.
Artículo
445 - Possani,L.D., Fletcher,P.L., Fletcher,M.D., Rode,G.S., Mochca-Morales,J., Lucas,S., Coronas,F.V., Alagon,A.C., Martin,B.M.. Structural and functional characteristics of toxins purified from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello.
Memorias do Instituto Butantan,
54 (2),
35-52.
Artículo
446 - Schleuning,W.D., Alagon,A., Boidol,W., Bringmann,P., Petri,T., Kratzschmar,J., Haendler,B., Langer,G., Baldus,B., Witt,W.. Plasminogen activators from the saliva of Desmodus rotundus (common vampire bat): unique fibrin specificity.
Annals of the New York Academy of Sciences,
667,
395-403.
*
Artículo
447 - Kratzschmar,J., Haendler,B., Langer,G., Boidol,W., Bringmann,P., Alagon,A., Donner,P., Schleuning,W.D.. The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression.
Gene,
105 (2),
229-237.
Note
448 - Vargas-Villarreal,J., Martin-Polo,J.J., Reynaud,E., Alagon,A.C.. A new affinity adsorbent for the purification of phospholipases A1 and A2 from animal venoms.
Toxicon,
29 (1),
119-124.
Artículo
449 - Zurita,M., Alagon,A., Vargas-Villarreal,J., Lizardi,P.M.. The Entamoeba histolytica rDNA episome: nuclear localization, DNAase I sensitivity map, and specific DNA-protein interactions.
Molecular Microbiology,
5 (8),
1843-1851.
Note
450 - Laclette,J.P., Alagon,A., Willms,K., Torre-Blanco,A.. Purification of antigen B from Taenia solium cysticerci by affinity to mammalian collagen.
Journal of Parasitology,
76 (2),
273-275.
Artículo
451 - Alagon,A.C., Guzman,H.S., Martin,B.M., Ramirez,A.N., Carbone,E., Possani,L.D.. Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch.
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology,
89 (1),
153-161.
452 - Alagon Cano, Alejandro. Enzimas hidroliticas del veneno de heloderma horridum horridum : fosfolipasa A2 y calicreina .
Doctorado en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
Artículo
453 - Alagon,A., Possani,L.D., Smart,J., Schleuning,W.D.. Helodermatine, a kallikrein-like, hypotensive enzyme from the venom of Heloderma horridum horridum (Mexican beaded lizard).
Journal of Experimental Medicine,
164 (6),
1835-1845.
Artículo
454 - Sosa,B.P., Alagon,A.C., Martin,B.M., Possani,L.D.. Biochemical characterization of the phospholipase A2 purified from the venom of the Mexican beaded lizard (Heloderma horridum horridum Wiegmann).
Biochemistry,
25 (10),
2927-2933.
*
Artículo
455 - King,T.P., Alagon,A.C., Kuan,J., Sobotka,A.K., Lichtenstein,L.M.. Immunochemical studies of yellowjacket venom proteins.
Molecular Immunology,
20 (3),
297-308.
*
Artículo
456 - Alagon,A.C., Maldonado,M.E., Julia,J.Z., Sanchez,C.R., Possani,L.D.. Venom from two sub-species of Heloderma horridum (Mexican beaded lizard): general characterization and purification of N-benzoyl-L-arginine ethyl ester hydrolase.
Toxicon,
20 (2),
463-475.
*
Artículo
457 - King,T.P., Alagon,A., Kochoumian,L., Kuan,J., Sobotka,A., Lichtenstein,L.M.. Limited proteolysis of antigens E and K from ragweed pollen.
Archives of Biochemistry and Biophysics,
212 (1),
127-135.
*
Artículo
458 - Possani,L., Steinmetz,W.E., Dent,M.A., Alagon,A.C., Wuthrich,K.. Preliminary spectroscopic characterization of six toxins from Latin American scorpions.
Biochimica et Biophysica Acta (BBA) - Protein Structure,
669 (2),
183-192.
*
Artículo
459 - Alagon,A.C., King,T.P.. Activation of polysaccharides with 2-iminothiolane and its uses.
Biochemistry,
19 (18),
4341-4345.
*
Artículo
460 - Alagon,A.C., Molinar,R.R., Possani,L.D., Fletcher,P.L., Cronan,J.E., Julia,J.Z.. Venom from the snake Bothrops asper Garman. Purification and characterization of three phospholipases A2.
Biochemical Journal,
185 (3),
695-704.
*
Artículo
461 - Possani,L.D., Fletcher,P.L., Alagon,A.B., Alagon,A.C., Julia,J.Z.. Purification and characterization of a mammalian toxin from venom of the Mexican scorpion, Centruroides limpidus tecomanus Hoffmann.
Toxicon,
18 (2),
175-183.
*
Note
462 - Possani,L.D., Sosa,B.P., Alagon,A.C., Burchfield,P.M.. The venom from the snakes Agkistrodon bilineatus Taylori and Crotalus durissus Totonacus: lethality, biochemical and immunological properties.
Toxicon,
18 (3),
356-360.
*
463 - Alagon Cano, Alejandro. Estudio sobre los venenos de varias especies zoologicas.
Instituto de Investigacions Biomedicas,
Maestria en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
Artículo
464 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Varela,M.J., Julia,J.Z.. Purification and characterization of a phospholipase A2 from the venom of the coral snake, Micrurus fulvius microgalbineus (Brown and Smith).
Biochemical Journal,
179 (3),
603-606.
*
Artículo
465 - Sosa,B.P., Alagon,A.C., Possani,L.D., Julia,J.Z.. Comparison of phospholipase activity with direct and indirect lytic effects of animal venoms upon human red cells.
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry,
64 (2),
231-234.
*
Nacional
466 - Arauco,R., Alagon,A.. [Propanolol in arterial hypertension. Beta-blockaders. Recent advances].
Prensa médica mexicana,
44 (5-6),
97-104.
*
Artículo
467 - King,T.P., Sobotka,A.K., Alagon,A., Kochoumian,L., Lichtenstein,L.M.. Protein allergens of white-faced hornet, yellow hornet, and yellow jacket venoms.
Biochemistry,
17 (24),
5165-5174.
*
Artículo
468 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Erickson,B.W.. Purification and properties of mammalian toxins from the venom of Brazilian Scorpion Tityus serrulatus Lutz and Mello.
Archives of Biochemistry and Biophysics,
180 (2),
394-403.
*
Artículo
469 - Frenk,J., Acuna,D.L., Bobadilla,J.L., Alagon,A.. [Liberal medicine and institutional medicine in Mexico].
Salud Publica de Mexico,
18 (3),
481-493.
*
- Teléfonos
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Oficina +52 (777) 329-1649
desde la CDMX 562-27649
Red UNAM 27649 -
Laboratorio +52 (777) 329-1602
desde la CDMX 562-27602
Red UNAM 27602