Dr. Alejandro Alagón Cano
Investigador Emérito
Alejandro Alagón Cano (Ciudad de México, 1954) es un médico, investigador, catedrático y académico mexicano. Se ha especializado en las áreas de biotecnología de los anticuerpos y toxinología (véase toxina), en la investigación para el mejoramiento de antivenenos y el desarrollo de nuevos antivenenos. Recibió el Premio Nacional de Ciencias y Artes en el 2005.
Biología Molecular y Bioquímica de venenos de animales ponzoñosos
Bioprocesos con aplicaciones biotecnológicas y para la generación de medicamentos biotecnológicos
Antivenenos para animales ponzoñosos con una pureza y refinamiento que reducen de forma importante las reacciones adversas típicas de estas terapias de emergencia.
Número de registros: 24
- Activos
- Vencidos
- Desarrollo de un antiveneno recombinante a partir de anticuerpos monoclonales para tratar pacientes envenenados por araña viuda negra (latrodectus sp.), DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2025 - 2027
- Consecuencias funcionales de la variación genómica, transcriptómica y proteómica en el veneno de las serpientes de cascabel de cola negra y sus implicaciones en el tratamiento con antiveneno, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2020 - 2024
- Venenos y antivenenos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2020 - 2025
- Desarrollo de un sistema para evaluar la respuesta inmune temprana y convaleciente de pacientes infectados con sars-cov-2 y de inmunoterápicos para enfermos en estado crítico por covid-19, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1900
- Caracterización del veneno de tres serpientes de importancia médica en méxico: investigación básica y mejoramiento de antivenenos., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2021 - 2023
- 2º curso de animales venenosos en méxico, biología, investigación y clínica, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2018
- Investigación de venenos de serpientes para el mejoramiento de antivenenos, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2018 - 2021
- Automatización de llenado de bolsas de agua para ratas y ratones del bioterio del instituto de biotecnología-unam, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2015 - 2016
- Caracterización funcional del veneno de agkistrodon, así como la respuesta inmune en caballos contra los mismos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2014 - 2018
- Biotecnología de anticuerpos terapéuticos y diagnósticos, y toxinología aplicada, PRESUPUESTO UNAM, 2014 - 2020
- Identificación, análisis molecular y expresión heteróloga de neurotoxinas provenientes de elápidos y vipéridos para la generación de antivenenos de alta calidad, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2014 - 2017
- Análisis molecular y expresión heteróloga de neurotoxinas provenientes del veneno de coral (elápidos) para la generación de antivenenos de alta calidad, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2011 - 2013
- Phase 2 clinical trial of coralmyn for coral snake bite, UNIVERSITY OF ARIZONA, 2010 - 2016
- Desarrollo de un antiveneno de cobertura europea para el tratamiento de la intoxicación por mordedura de serpiente, FONDO DE COOPERACIÓN INTERNACIONAL EN CIENCIA Y TECNOLOGÍA UNIÓN EUROPEA - MÉXICO, 2009 - 2012
- Reconocimiento cruzado de venenos de coralillos de norteamerica, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2009
- Proyecto piloto referente al estudio del sistema linfático; a llevarse a cabo durante la segunda reunión de grupo de investigación sobre linfotoxicología, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2008 - 2009
- Toxoides recombinantes de arañas latrodectus y loxosceles., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2005
- Inhibición de funciones celulares en células humanas y de entamoeba histolytica mediante pna antisentido y antigene convalentemente modificados y usando glóbulos rojos acarreadores., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2002 - 2004
- Anticuerpos recombinantes humanos: obtención y evaluación funcional para el desarrollo de antivenenos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2000 - 2002
- Repertorios inteligentes de anticuerpos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2000 - 2002
- Caracterización de venenos y toxinas selectos de arañas mexicanas, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1999 - 2001
- Inhibición de funciones celulares en células humanas y en entamoeba histolytica mediante ácidos péptido nucleicos (pna) antisense y antigene., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1999 - 2002
- Enfoques moleculares para el estudio de la vía secretoria en entamoeba histolytica (3a. etapa), DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1997 - 2000
- Diseño de moléculas mejoradas de pna (ácido péptido-nucléico) para la expresión de genes específicos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1996 - 1998
Nivel D del PRIDE
Nivel Investigador Emérito del SNII
Nivel Investigador Emérito del SNII
Doctorado, en Ciencias, Instituto de Investigaciones Biomedicas, UNAM (1983)
Maestría, en Ciencias, Instituto de Investigaciones Biomedicas, UNAM (1980)
Licenciatura, Medico Cirujano, Fac. de Medicina, UNAM (1978)
Premio Luis Elizondo al sentido humano 2013, Sistema Tecnológico de Monterrey, 2013
Premio Nacional de Ciencias y Artes, Gobierno de la República, 2005
Premio UNAM 2004 Innovación Tecnológica, 2004
- Activos
- Graduados
-
Doctorado
-
Generación de antiveneno experimental neutralizante del veneno de abeja (Apis mellifera) y la reacción anafiláctica
-
Maestría
-
Audrey Michelle Rodríguez Solís
Cuantificación de veneno, familias proteicas y antiveneno en muestra de sangre de pacientes mordidos por vipéridos y elápidos mexicanos. -
Producción de un AcM neutralizante del veneno de L. mactans a partir de fragmentos recombinantes de la alfa-latrotoxina
-
Licenciatura
1 - Yanez Mendoza, Manuel Francisco (2024). Caracterizacion funcional del veneno de la serpiente de coral mexicana Micrurus diastema .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
2 - Losoya Uribe, Luis Fernando (2024). Obtencion de un anticuerpo monoclonal neutralizante de la actividad esfingomielinasa D de Loxosceles boneti (Gertsch, 1958), como candidato en el desarrollo de un anticuerpo recombinante quimerico.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
3 - Corkidi Zajur, Tania (2023). Caracterizacion de la sphenotoxina de Ophryacus sphenophrys y su comparacion con la crotoxina clasica .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
4 - Aguayo Avalos, Oscar (2023). Evolucion de titulos de anticuerpos y potencias neutralizantes de sueros de caballo hiperinmunizados con mezclas complejas de venenos de viperidos y elapidos.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
5 - Colis Torres, Andrea (2021). Caracterizacion intraespecifica del veneno de Crotalus basiliscus (Cope, 1864) y su neutralizacion con un antiveneno mexicano.
Instituto de Biotecnología,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Alagon Cano, Alejandro
6 - Neri Castro, Edgar Enrique (2021). Farmacocinética en sangre y en linfa del veneno de la cascabel neotropical (Crotalus simus) en un modelo ovino.
Instituto de Investigaciones Biomedicas,
Doctorado en Ciencias Biomedicas,
UNAM.
*
Asesor: Alagon Cano, Alejandro
7 - Ponce Lopez, Jose Roberto (2020). Expresion heterologa de crotamina de Crotalus molossus nigrescens fusionada a esfingomielinasa D de loxosceles en Escherichia coli, para su utilizacion como posible inmunogeno.
Instituto de Biotecnologia,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Alagon Cano, Alejandro
8 - Benard Valle, Melisa (2020). Caracterizacion funcional y analisis de especificidad del veneno de la serpiente de coral Micrurus browni browni.
Instituto de Biotecnologia,
Doctorado en Bioquímicas,
UNAM.
Asesor: Alagon Cano, Alejandro
9 - Sarmiento Acuña, Karen Solanyi (2020). Comparación de la especificidad y capacidad neutralizante de dos antivenenos antiofídicos retados con veneno de serpiente del género Bothrops de Colombia.
Facultad de Medicina,
Maestría en Toxicología,
Universidad Nacional de Colombia.
*
Asesor: Castiblanco Rodríguez, Ana Lucía, Alagón Cano, Alejandro
10 - Corkidi Zajur, Tania (2020). Biodistribución de fragmentos de inmunoglobulinas tipo F(ab)? 2 en ratones, por análisis de imágenes.
Instituto de Investigacion en Ciencias Basicas y Aplicadas,
Licenciatura en Ciencias,
UAEM.
*
Asesor: Alagon Cano, Alejandro
11 - Castillo Perez, Irene Maria (2019). Producción de conjugados de crotamina y su evaluación como inmunógenos.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
12 - Borja Jiménez, Juan Miguel (2019). Variabilidad genética y caracterización bioquímica de las
metaloproteinasas y la toxina mojave de Crotalus scutulatus y Crotalus molossus del desierto
Chihuahuense.
Facultad de Ciencias Químicas,
Doctorado en Ciencias Biomédicas,
Universidad Juárez del Estado de Durango.
*
Asesor: Pérez Morales,Rebeca, Alagón Cano, Alejandro
13 - Barcenas Arriaga, Sergio (2018). Caracterizacion bioquimica y biologica del veneno de Bothrops asper (Garman, 1884) de Mexico .
Facultad de Ciencias,
Maestria en Ciencias Biologicas,
UNAM.
*
Asesor: Alagon Cano, Alejandro
14 - Roman Dominguez, Luis (2018). Aislamiento y caracterización de componentes con actividad edematizante presentes en el veneno de la serpiente Agkistrodon bilineatus.
Facultad de Medicina,
Maestria en Medicina Molecular,
UAEM.
*
Asesor: Petricevich, Vera Lucia, Alagon Cano, Alejandro
15 - Dzib Hau, Maria Fernanda (2016). Caracterizacion de los principales compuestos presentes en secreciones obtenidas de las glandulas parotidas de rhinella marina.
Instituto de Biotecnologia,
76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
16 - Vergara Bahena, Irene (2015). Caracterizacion del veneno de micrurus fulvius y biodistribucion in vivo de su principal toxina radiomarcada con 67galio.
Instituto de Biotecnologia,
94 paginas,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
17 - Hernandez Davila, Isabel Arely (2015). Crotoxina en el veneno de la serpiente de cascabel crotalus simus en Mexico : su relacion con la toxicidad y distribucion geografica .
Instituto de Biotecnologia,
76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
18 - Paniagua Meza, Dayanira (2014). Participacion del sistema linfatico en la absorcion y distribucion del veneno de micrurus fulvius.
Instituto de Biotecnologia,
74 paginas,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
19 - Mendoza Vera, Miguel Angel (2014). Expresion, purificacion y caracterizacion de la esfingomielinasa D recombinante de rhipicephalus microplus .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
20 - Guerrero Garzon, Jaime Felipe (2014). Clonacion, expresion y caracterizacion de alfaneurotoxinas de serpientes de coral mexicanas .
Instituto de Biotecnologia,
83 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
21 - Carbajal Saucedo, Alejandro (2014). Caracterizacion biologica, bioquimica e inmunoquimica del veneno de Micrurus laticollaris : bases para el desarrollo de un antiveneno de amplio espectro contra coralillos .
Instituto de Biotecnologia,
90 paginas,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
22 - Barron Castillo, Ulises (2014). Expresion de la alfaneurotoxina mlata1 de micrurus laticollaris en pichia pastoris y evaluacion de su uso como inmunogeno.
Instituto de Biotecnologia,
76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
23 - Rosa Hernandez, Guillermo de la (2011). Produccion de toxoides de serpientes africanas mediante radiacion gamma.
Instituto de Biotecnologia,
93 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
24 - Chavez Mendez, Ariana (2011). Participacion de los productos fosfoceramida y lisofosfatidato generados por la esfingomielinasa D del veneno de arana loxosceles, en la toxicidad de la enzima.
Instituto de Biotecnologia,
vi, 76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
25 - Calderon Corona, Arlene (2011). Caracterizacion de la respuesta inmune humoral en caballos contra el veneno de Micrurus tener.
Instituto de Biotecnologia,
78 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
26 - Benard Valle, Melisa (2011). Caracterizacion bioquimica del veneno de la serpiente de coral Micrurus tener.
Instituto de Biotecnologia,
42 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
27 - Vergara Bahena, Irene (2010). Influencia de la via de administracion en la capacidad neutralizante in vivo de dos antivenenos .
Instituto de Biotecnologia,
xi, 73 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
28 - Jimenez Martinez, Lucia (2009). Neutralizacion de esfingomielinasa D recombuinante de Loxosceles boneti con varias preparaciones derivadas de suero hiperinmune de caballo .
FMVZ,
Medico Veterinario Zootecnista,
UNAM.
*
Asesor: Alagon Cano, Alejandro
29 - Moctezuma Gonzalez, Claudia Lizbeth (2008). Produccion de un fragmento de anticuerpo recombinante quimerico anti esfingomielinasa D contra la mordedura de la arana Loxosceles.
Instituto de Biotecnologia,
53 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
30 - Chavez Mendez, Ariana (2007). Desarrollo, optimizacion y validacion de un metodo analitico tipo ELISA para cuantificar veneno de escorpion Centruroides en plasma humano .
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
Asesor: Alagon Cano, Alejandro
31 - Olguin Perez, Laura Patricia (2006). Caracterizacion de la actividad enzimatica de la esfingomielinasa D del veneno de las aranas violinistas Loxosceles boneti, L. reclusa Y L. laeta .
Instituto de Biotecnologia,
41, [2] paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
32 - Ramos Cerrillo, Blanca Margarita (2005). Produccion, evaluacion y caracterizacion de los inmunogenos recombinantes de las esfingomielinasa de L. boneti, L. reclusa y L. laeta .
Instituto de Biotecnologia,
(97, [15] paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
33 - Prud'Homme Sanchez, Monica Adriana (2004). Produccion y evaluacion de antigenos recombinantes de la alatrotoxina de Latrodectus mactans.
Instituto de Biotecnologia,
(vii, 77 paginas,
Maestria en Ciencias (Bioquimica),
UNAM.
Asesor: Alagon Cano, Alejandro
34 - Carbajal Saucedo, Alejandro (2004). Comparacion inmunoquimica del veneno de serpientes de coral (Elapidae : Mirurus, Micruroides) mexicanas .
Instituto de Biotecnologia,
53 paginas,
Maestria en Ciencias (Bioquimica),
UNAM.
Asesor: Alagon Cano, Alejandro
35 - Fuentes Silva, Deyanira (2003). Plegamiento in vitro de una toxina sintetica de arana.
Instituto de Biotecnologia,
76, VI paginas ,
Maestria en Ciencias Quimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
36 - Ramos Cerrillo, Blanca Margarita (2002). Comparacion bioquimica, inmunologica y toxinologica de los venenos de Loxosceles boneti y Loxosceles reclusa .
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
Asesor: Alagon Cano, Alejandro
37 - Ramos Ibarra, Marco Antonio (2001). Clonacion y localizacion intracelular de la subunidad de 54 kDa de la particula de reconocimiento de la secuencia senal (SRP54) de Entamoeba histolytica .
Instituto de Biotecnologia,
74, VII paginas,
Doctor en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
38 - Ortiz Suri, Ernesto (1998). Moleculas de PNA en sistemas fluorescentes de deteccion por hibridacion en la discriminacion de alelos .
Instituto de Biotecnologia,
56, [10] paginas,
Doctorado en Biotecnologia,
UNAM.
39 - Gonzalez Juarez, Carlos Antonio (1996). Desarrollo de una prueba diagnostica para la deteccion de hipotiroidismo congenito empleando anticuerpos monoclonales.
Instituto de Biotecnologia,
87, VI paginas,
Maestria en Biotecnologia,
UNAM.
Asesor: Alagon Cano, Alejandro
40 - Hernandez Vargas, Rene (1995). Caracterizacion molecular de un fragmento de un gene similar a HSP70 de Entamoeba histolytica.
Instituto de Biotecnologia,
57 paginas,
Maestria en Biotecnologia,
UNAM.
41 - Mercado Besserer, Gabriel Cuauhtemoc (1994). Obtencion y caracterizacion de un fragmento del gene SRP54 de Entamoeba histolytica.
Instituto de Biotecnologia,
Licenciatura en Investigacion Biomedica Basica,
UNAM.
42 - Herrera Medina, Enrique Macario (1992). Caracterizacion bioquimica del veneno de la hormiga Pogonomyrmex rugosus con enfasis en la fosfolipasa A1 .
Instituto de Biotecnologia,
53 paginas,
Maestria en Biotecnologia,
UNAM.
Asesor: Alagon Cano, Alejandro
43 - Cuevas Aguirre, Delia Anatolia (1992). Caracterizacion bioquimica de saliva de triatominos mexicanos.
Maestria en Biotecnologia,
UNAM.
44 - Vargas Villarreal, Javier (1991). Aislamiento y caracterizacion de una fosfolipasa A2 de Entamoeba histolytica con actividad litica directa .
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
64 paginas,
Doctorado en Investigacion Biomedica Basica,
UNAM.
Asesor: Alagon Cano, Alejandro
45 - Astorga Chaidez, Eleuterio (1991). Actividad inhibitoria de la agregacion plaquetaria por la saliva del murcielago hematofogo.
Instituto de Biotecnologia,
Maestría en Biotecnología,
UNAM.
Asesor: Alagon Cano, Alejandro
46 - Sosa Pineda, Beatriz (1988). Helodermatidina, una proteasa del veneno del monstruo de cuentas (heloderma horridum horridum) que activa plasminogeno .
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
42 paginas,
Maestria en Investigacion Biomedica Basica,
UNAM.
Asesor: Alagon Cano, Alejandro
47 - Amezcua Lopez, Jose (1987). Caracterizacion bioquimica del veneno de avispas Polistesdoxsalis (Fabricius) y Polivia occidentalis nigritella du Bysson.
Facultad de Ciencias,
UNAM.
*
Asesor: Alagon Cano, Alejandro
Total de publicaciones: 214
- Tipo
- Fecha
Artículo in press
48 - Alfaro-Chinchilla,A., Lomonte,B., Zuniga,L., Acevedo,M., Neri-Castro,E., Alagon,A., Bonilla,F., Diaz,C., Sasa,M. (2025). Venom composition, toxicity and cross-neutralization by PoliVal-ICP antivenom, of Mesoamerican jumping pitvipers genus Metlapilcoatlus (Viperidae: Crotalinae).
Transactions of the Royal Society of Tropical Medicine and Hygiene,
Advance access,
trae120.
Artículo
49 - Borja,M., Castaneda-Gaytan,G., Alagon,A., Strickland,J.L., Parkinson,C., Gutierrez-Martinez,A., Rodriguez-Lopez,B., Zarzosa,V., Lomonte,B., Saviola,A.J., Fernandez,J., Smith,C.F., Hansen,K.C., Perez-Robles,A., Castaneda-Perez,S., Hirst,S.R., Olvera-Rodriguez,F, Fernandez-Badillo,L, Sigala,J, Jones,J, Montano-Rubalcava,C, Ramirez-Chaparro,R., Margres,M., Acosta-Campana,G., Neri-Castro,E. (2025). Venom variation and ontogenetic changes in the Crotalus molossus complex: Insights into composition, activities, and antivenom neutralization.
Comparative Biochemistry and Physiology - C Toxicology and Pharmacology,
290,
110129.
Artículo
50 - Damsbo,A., Benard-Valle,M., Jansen,T., Burlet,N.J., Overath,M.D., Guadarrama-Martinez,A., Boddum,K., Alagon,A., Rivera-de-Torre,E., Laustsen,A.H. (2025). Discovery of broadly neutralizing V(H)Hs against short-chain a-neurotoxins using a consensus toxin as an antigen.
MAbs,
17 (1),
2522838.
Artículo
51 - Damsbo,A., Burlet,N.J., Fernandez-Quintero,M.L., Benard-Valle,M., Overath,M.D., Guadarrama-Martinez,A., Vlamynck,A., Bisbo,I., Villalobos,C., Tulika,T., Alagon,A., Loeffler,J.R., Ward,A.B., Boddum,K., Morth,J.P., Rivera-de-Torre,E., Laustsen,A.H. (2025). Structural mechanisms behind the neutralisation of long-chain a-neurotoxins by broadly neutralising V(H)Hs discovered using a consensus antigen.
Communications Chemistry,
8 (1),
209.
Artículo in press
52 - Seneci,L., Chandrasekara,U., Chowdhury,A., Zarzosa,V., Guadarrama-Martinez,A., Neri-Castro,E., Alagon,A., Soria,R., Fry,B.G. (2025). The X Factor: Regional differences in the level of ontogenetic variations in procoagulant venom activity in the Northwestern Neotropical Rattlesnake (Crotalus culminatus).
Biochimie,
Jul 16 [Online ahead of print].
Artículo
53 - Zarzosa,V., Neri-Castro,E., Lomonte,B., Fernandez,J., Rodriguez-Barrera,G., Rodriguez,B., Rodriguez-Solis,A.M., Olvera-Rodriguez,A., Benard-Valle,M., Saviola,A., Garcia-Vazquez,U.O., Fernandez-Badillo,L, Morales-Capellan,N., Borja,M., Zamudio,F., Alagon,A. (2025). Integrative transcriptomic, proteomic, biochemical and neutralization studies on the venom of Micrurus ephippifer.
Journal of Proteomics,
316,
105416.
Artículo
54 - Benard-Valle,M., Wouters,Y., Ljungars,A., Nguyen,G.T.T., Ahmadi,S., Ebersole,T.W., Dahl,C.H., Guadarrama-Martinez,A., Jeppesen,F., Eriksen,H., Rodriguez-Barrera,G., Boddum,K., Jenkins,T.P., Bjorn,S.P., Schoffelen,S., Voldborg,B.G., Alagon,A., Laustsen,A.H. (2024). In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model.
Nature Communications,
15 (1),
4310.
Artículo
55 - Bourke,L.A., Zdenek,C.N., Huynh,T.M., Hodgson,W.C., Alagon,A., Castro,E.N., Jones,J., Fry,B.G. (2024). Fangs and Foliage: Unearthing the Haemotoxic Secrets of Cannabis-Dwelling Rattlesnakes.
Toxicon,
244,
107756.
Artículo
56 - Campbell,S.I.D., Chow,C.Y., Neri-Castro,E., Alagon,A., Gomez,A., Soria,R., King,G.F., Fry,B.G. (2024). Taking the sting out of scorpions: Electrophysiological investigation of the relative efficacy of three antivenoms against medically significant Centruroides species.
Comparative Biochemistry and Physiology C Toxicology and Pharmacology,
283,
109977.
Artículo
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76,
386-393.
Artículo
127 - Boyer,L.V., Chase,P.B., Degan,J.A., Figge,G., Buelna-Romero,A., Luchetti,C., Alagon,A. (2013). Subacute coagulopathy in a randomized, comparative trial of Fab and F(ab') antivenoms.
Toxicon,
74,
101-108.
Artículo
128 - Boyer,L.V., Theodorou,A.T., Chase,P.B., Osnaya,N., Berg,M., Mallie,J., Carbajal,Y., de Jesus-Hernandez,T., Olvera,F., Alagon,A. (2013). Effectiveness of Centruroides scorpion antivenom compared to historical controls.
Toxicon,
76,
377-385.
Artículo
129 - Low,D.H., Sunagar,K., Undheim,E.A., Ali,S.A., Alagon,A.C., Ruder,T., Jackson,T.N., Pineda-Gonzalez,S., King,G.F., Jones,A., Antunes,A., Fry,B.G. (2013). Dracula's children: Molecular evolution of vampire bat venom.
Journal of Proteomics,
89C,
95-111.
Artículo
130 - Neri-Castro,E., Lomonte,B., Gutierrez,M.C., Alagon,A., Gutierrez,J.M. (2013). Intraspecies variation in the venom of the rattlesnake Crotalus simus from Mexico: Different expression of crotoxin results in highly variable toxicity in the venoms of three subspecies.
Journal of Proteomics,
87,
103-121.
Artículo
131 - Oukkache,N., Chgoury,F., Lalaoui,M., Alagon-Cano,A., Ghalim,N. (2013). Comparison between two methods of scorpion venom milking in Morocco.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
19 (1),
5.
Artículo
132 - Vazquez,H., Olvera,F., Alagon,A., Sevcik,C. (2013). Production of anti-horse antibodies induced by IgG, F(ab') and Fab applied repeatedly to rabbits. Effect on antivenom pharmacokinetics.
Toxicon,
76,
362-369.
Artículo
133 - Clement,H., Olvera,A., Rodriguez,M., Zamudio,F., Palomares,L.A., Possani,L.D., Odell,G.V., Alagon,A., Sanchez-Lopez,R. (2012). Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom.
Toxicon,
60 (7),
1223-1227.
Artículo
134 - Clement,H., Costa de Oliveira,V, Zamudio,F.Z., Lago,N.R., Valdez-Cruz,N.A., Valle,M.B., Alagon,A.C., Possani,L.D., de Roodt,A.R. (2012). Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A(2) from Bothrops (Rhinocerophis) ammodytoides Venom.
Toxicon,
60 (7),
1314-1323.
Artículo
135 - Koludarov,I., Sunagar,K., Undheim,E.A., Jackson,T.N., Ruder,T., Whitehead,D., Saucedo,A.C., Mora,G.R., Alagon,A.C., King,G., Antunes,A., Fry,B.G. (2012). Structural and Molecular Diversification of the Anguimorpha Lizard Mandibular Venom Gland System in the Arboreal Species Abronia graminea.
Journal of Molecular Evolution,
75 (5-6),
168-183.
Artículo
136 - Paniagua,D., Jimenez,L., Romero,C., Vergara,I., Calderon,A., Benard,M., Bernas,M.J., Rilo,H., de Roodt,A., D'Suze,G., Witte,M.H., Boyer,L., Alagon,A. (2012). Lymphatic route of transport and pharmacokinetics of Micrurus fulvius (coral snake) venom in sheep.
Lymphology,
45 (4),
144-153.
Artículo
137 - Archundia,I.G., de Roodt,A.R., Ramos-Cerrillo,B., Chippaux,J.P., Olguin-Perez,L., Alagon,A., Stock,R.P. (2011). Neutralization of Vipera and Macrovipera venoms by two experimental polyvalent antisera: A study of paraspecificity.
Toxicon,
57 (7-8),
1049-1056.
Artículo
138 - Redaelli,E., Restano-Cassulini,R., Fuentes-Silva,D., Clement,H., Schiavon,E., Zamudio,F.Z., Odell,G., Arcangeli,A., Clare,J.J., Alagon,A., Rodriguez de la Vega,R.C., Possani,L.D., Wanke,E. (2010). Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.
Journal of Biological Chemistry,
285 (6),
4130-4142 .
Artículo
139 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2010). Pharmacokinetics of a F(ab')(2) scorpion antivenom administered intramuscularly in healthy human volunteers.
International Immunopharmacology,
10 (11),
1318-1324.
Artículo
140 - Vazquez,H., Olvera,F., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2010). Pharmacokinetics in rabbits and anti-sphingomyelinase D neutralizing power of Fab, F(ab')2, IgG and IgG(T) fragments from hyper immune equine plasma.
International Immunopharmacology,
10 (4),
447-454.
Artículo
141 - Boyer,L.V., Theodorou,A.A., Berg,R.A., Mallie,J., Chavez-Mendez,A., Garcia-Ubbelohde,W., Hardiman,S., Alagon,A. (2009). Antivenom for critically ill children with neurotoxicity from scorpion stings.
New England Journal of Medicine,
360 (20),
2090-2098 (Reply 2009 vol 361 632).
Artículo
142 - Casasola,A., Ramos-Cerrillo,B., de Roodt,A.R., Saucedo,A.C., Chippaux,J.P., Alagon,A., Stock,R.P. (2009). Paraspecific neutralization of the venom of African species of cobra by an equine antiserum against Naja melanoleuca: A comparative study.
Toxicon,
53 (6),
602-608.
Artículo
143 - Chase,P., Boyer-Hassen,L., McNally,J., Vazquez,H.L., Theodorou,A.A., Walter,F.G., Alagon,A. (2009). Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients.
Clinical Toxicology,
47 (1),
24-28.
Artículo
144 - Corzo,G., Bernard,C., Clement,H., Villegas,E., Bosmans,F., Tytgat,J., Possani,L.D., Darbon,H., Alagon,A. (2009). Insecticidal peptides from the theraposid spider Brachypelma albiceps: A NMR-based model of Ba2.
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics,
1794 (8),
1190-1196.
Artículo
145 - Chippaux,J.P., Alagon,A. (2008). [Envenomation and poisoning by venomous or poisonous animals. VII: arachnidism in the New World].
Medecine Tropicale,
68 (3),
215-221.
Artículo
146 - Corzo,G., Diego-Garcia,E., Clement,H., Peigneur,S., Odell,G., Tytgat,J., Possani,L.D., Alagon,A. (2008). An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.
Peptides,
29 (11),
1901-1908.
Artículo
147 - Ramos-Cerrillo,B., de Roodt,A.R., Chippaux,J.P., Olguin,L., Casasola,A., Guzman,G., Paniagua-Solis,J., Alagon,A., Stock,R.P. (2008). Characterization of a new polyvalent antivenom (Antivipmyn((R)) Africa) against African vipers and elapids.
Toxicon,
52 (8),
881-888.
Artículo
148 - Chippaux,J.P., Massougbodji,A., Stock,R.P., Alagon,A. (2007). Clinical Trial of an F(ab')2 Polyvalent Equine Antivenom for African Snake Bites in Benin.
American Journal of Tropical Medicine and Hygiene,
77 (3),
538-546.
Artículo
149 - Clement,H., Odell,G., Zamudio,F.Z., Redaelli,E., Wanke,E., Alagon,A., Possani,L.D. (2007). Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels.
Toxicon,
50 (1),
65-74.
Artículo
150 - de Roodt,A.R., Estevez-Ramirez,J., Litwin,S., Magana,P., Olvera,A., Alagon,A. (2007). Toxicity of two North American Loxosceles (brown recluse spiders) venoms and their neutralization by antivenoms.
Clinical Toxicology,
45 (6),
678-687.
Carta
151 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R., Algaron,A., Fox,J.W. (2007). Upregulation of IL-6, IL-8, CXCL1, and CXCL2 Dominates Gene Expression in Human Fibroblast Cells Exposed to Loxosceles reclusa Sphingomyelinase D: Insights into Spider Venom Dermonecrosis.
Journal of Investigative Dermatology,
127 (5),
1264-1266.
Carta
152 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R.P., Alagon,A., Fox,J.W. (2007). Upregulation of cytokine expression in fibroblasts exposed to Loxosceles sphingomyelinase D: What is the trigger? - Response to Moolenaar et al.
Journal of Investigative Dermatology,
127 (5),
1267-1268.
Artículo
153 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Alagon,A. (2007). Antigenic cross-reactivity between sixteen venoms from scorpions belonging to six genera.
Clinical Toxicology,
45 (2),
158-163.
Artículo
154 - Almagro,J.C., Martinez,L., Smith,S.L., Alagon,A., Estevez,J., Paniagua,J. (2006). Analysis of the horse V(H) repertoire and comparison with the human IGHV germline genes, and sheep, cattle and pig V(H) sequences.
Molecular Immunology,
43 (11),
1836-1845.
Artículo
155 - Olvera,A., Ramos-Cerrillo,B., Estevez,J., Clement,H., de Roodt,A., Paniagua-Solis,J., Vazquez,H., Zavaleta,A., Salas-Arruz,M., Stock,R.P., Alagon,A. (2006). North and South American Loxosceles spiders: Development of a polyvalent antivenom with recombinant sphingomyelinases D as antigens.
Toxicon,
48 (1),
64-74.
Artículo
156 - de Roodt,A.R., Estevez-Ramirez,J., Paniagua-Solis,J.F., Litwin,S., Carvajal-Saucedo,A., Dolab,J.A., Robles-Ortiz,L.E., Alagon,A. (2005). [Toxicity of venoms from snakes of medical importance in Mexico].
Gaceta Medica de Mexico,
141 (1),
13-21.
Artículo
157 - de Roodt,A.R., Salomon,O.D., Orduna,T.A., Robles-Ortiz,L.E., Paniagua-Solis,J.F., Cano,A.A. (2005). Poisoning by bee sting.
Gaceta Medica de Mexico,
141 (3),
215-222.
Artículo
158 - Ramos,M.A., Sanchez-Lopez,R., Mares,R.E., Olvera,F., Alagon,A. (2005). Identification of an Entamoeba histolytica gene encoding a protein disulfide isomerase that functionally complements the dsbA mutation in Escherichia coli.
Molecular and Biochemical Parasitology,
143 (2),
236-240.
Artículo
159 - Sadurni,P., Alagon,A., Aliev,R., Burillo,G., Hoffman,A.S. (2005). Immobilization of streptavidin-horseradish peroxidase onto a biotinylated poly(acrylic acid) backbone that had been radiation-grafted to a PTFE film.
Journal of Biomaterials Science-Polymer Edition,
16 (2),
181-187.
Artículo
160 - Salgado,M., Villagomez-Castro,J.C., Rocha-Rodriguez,R., Sabanero-Lopez,M., Ramos,M.A., Alagon,A., Lopez-Romero,E., Sanchez-Lopez,R. (2005). Entamoeba histolytica: Biochemical and molecular insights into the activities within microsomal fractions.
Experimental Parasitology,
110 (4),
363-373.
Artículo
161 - Sanchez,R., Saralegui,A., Olivos-Garcia,A., Scapolla,C., Damonte,G., Sanchez-Lopez,R., Alagon,A., Stock,R.P. (2005). Entamoeba histolytica: intracellular distribution of the sec61alpha subunit of the secretory pathway and down-regulation by antisense peptide nucleic acids.
Experimental Parasitology,
109 (4),
241-251.
Artículo
162 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Mancilla-Nava,R., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2005). Pharmacokinetics of a F(ab')(2) scorpion antivenom in healthy human volunteers.
Toxicon,
46 (7),
797-805.
Artículo
163 - de Roodt,A.R., Paniagua-Solis,J.F., Dolab,J.A., Estevez-Ramirez,J., Ramos-Cerrillo,B., Litwin,S., Dokmetjian,J.C., Alagon,A. (2004). Effectiveness of two common antivenoms for North, Central, and South American Micrurus envenomations.
Journal of Toxicology - Clinical Toxicology,
42 (2),
171-178.
Artículo
164 - Ramos-Cerrillo,B., Olvera,A., Odell,G.V., Zamudio,F., Paniagua-Solis,J., Alagon,A., Stock,R.P. (2004). Genetic and enzymatic characterization of sphingomyelinase D isoforms from the North American fiddleback spiders Loxosceles boneti and Loxosceles reclusa.
Toxicon,
44 (5),
507-514 .
Artículo
165 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Aguilar,V., Alagon,A. (2003). Relationship between plasmatic levels of various cytokines, tumour necrosis factor, enzymes, glucose and venom concentration following Tityus scorpion sting.
Toxicon,
41 (3),
367-375.
Artículo
166 - Nieto-Sotelo,J., Martinez,L.M., Ponce,G., Cassab,G.I., Alagon,A., Meeley,R.B., Ribaut,J.M., Yang,R. (2002). Maize HSP101 Plays Important Roles in Both Induced and Basal Thermotolerance and Primary Root Growth.
Plant Cell,
14 (7),
1621-1633.
Artículo
167 - Ramos,M.A., Sanchez-Lopez,R., Olvera,F., Alagon,A. (2002). Entamoeba histolytica genomic organization: identification, structure, and phylogenetic relationship of two serine-threonine protein kinases.
Experimental Parasitology,
100 (2),
135-139.
Artículo
168 - Sanchez,R., Alagon,A., Stock,R.P. (2002). Entamoeba histolytica: intracellular distribution of the proteasome.
Experimental Parasitology,
102 (3-4),
187-190.
Artículo
169 - Juarez,P., Sanchez-Lopez,R., Stock,R.P., Olvera,A., Ramos,M.A., Alagon,A. (2001). Characterization of the Ehrab8 gene, a marker of the late stages of the secretory pathway of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
116 (2),
223-228.
Artículo
170 - Stock,R.P., Olvera,A., Sanchez,R., Saralegui,A., Scarfi,S., Sanchez-Lopez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Alagon,A. (2001). Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers.
Nature Biotechnology,
19 (3),
231-234.
Artículo
171 - Gutierrez,A., Sanchez-Lopez,R., Ramos,M.A., Alagon,A. (2000). Cloning of the Entamoeba histolytica STT3 gene, a subunit of the oligosaccharyltransferase complex.
Archives of Medical Research,
31 (4 Suppl),
S162-S164.
Artículo
172 - Juarez,P., Sanchez-Lopez,R., Ramos,M.A., Stock,R.P., Alagon,A. (2000). Rab8 as a molecular model of vesicular trafficking to investigate the latter steps of the secretory pathway in Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S157-S159.
Artículo
173 - Ramos,M.A., Alagon,A. (2000). Molecular cloning of a gene encoding a PDI-like protein from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S173-S175.
Artículo
174 - Ramos,M.A., Sanchez-Lopez,R., Alagon,A. (2000). Genomic organization of a 7 Kb gene cluster from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S263-S265.
Artículo
175 - Sanchez-Lopez,R., Gutierrez,A., Juarez,P., Olvera,A., Olvera,F., Ramos,M.A., Sanchez,R., Saralegui,A., Stock,R.P., Alagon,A. (2000). Molecular genetics of the secretory pathway in Entamoeba histolytica: an overview.
Archives of Medical Research,
31 (4 Suppl),
S151-S152.
Artículo
176 - Sanchez-Lopez,R., Siminovich,B., Alagon,A. (2000). Entamoeba histolytica codes for a protein homologue of the Sec61 alpha subunit, a component of the endoplasmic reticulum translocon.
Archives of Medical Research,
31 (4 Suppl),
S168-S170.
Artículo
177 - Stock,R.P., Olvera,A., Scarfi,S., Sanchez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Landt,O., Alagon,A. (2000). Inhibition of neomycin phosphorotransferase expression in Entamoeba histolytica with antisense peptide nucleic acid (PNA) oligomers.
Archives of Medical Research,
31 (4 Suppl),
S271-S272.
Artículo
178 - Que,X., Kim,D., Alagon,A., Hirata,K., Shike,H., Shimizu,C., Gonzalez,A., Burns,J.C., Reed,S.L. (1999). Pantropic retroviral vectors mediate gene transfer and expression in Entamoeba histolytica.
Molecular and Biochemical Parasitology,
99 (2),
237-245.
Artículo
179 - Sanchez-Gonzalez,M., Alagon,A., Rodriguez-Sotres,R., Lopez-Munguia,A. (1999). Proteolytic processing of dextransucrase of Leuconostoc mesenteroides.
Fems Microbiology Letters,
181 (1),
25-30.
Artículo
180 - Sanchez-Lopez,R., Gama-Castro,S., Ramos,M.A., Merino,E., Lizardi,P.M., Alagon,A. (1998). Cloning and expression of the Entamoeba histolytica ERD2 gene.
Molecular and Biochemical Parasitology,
92 (2),
355-359.
Artículo
181 - Vargas-Villarreal,J., Olvera-Rodriguez,A., Mata-Cardenas,B.D., Martinez-Rodriguez,H.G., Said-Fernandez,S., Alagon-Cano,A. (1998). Isolation of an Entamoeba histolytica intracellular alkaline phospholipase A(2).
Parasitology Research,
84 (4),
310-314.
Artículo; Actas Paper
Artículo
183 - Ramos,M.A., Mercado,G.C., Salgado,L.M., Sanchez-Lopez,R., Stock,R.P., Lizardi,P.M., Alagon,A. (1997). Entamoeba histolytica contains a gene encoding a homologue to the 54 kDa subunit of the signal recognition particle.
Molecular and Biochemical Parasitology,
88 (1-2),
225-235.
Artículo; Actas Paper
184 - Ramos,M.A., Stock,R.P., Lizardi,P.M., Alagon,A. (1997). The secretory pathway of Entamoeba histolytica: characterization and expression of the SRP54 gene.
Archives of Medical Research,
28 (Spec No:56-8.),
56-58.
Artículo
185 - Ramos,M.A., Stock,R.P., Sanchez-Lopez,R., Olvera,F., Lizardi,P.M., Alagon,A. (1997). The Entamoeba histolytica proteasome alpha-subunit gene.
Molecular and Biochemical Parasitology,
84 (1),
131-135.
Artículo; Actas Paper
186 - Sanchez-Lopez,R., Gama-Castro,S., Lizardi,P.M., Alagon,A. (1997). The secretory pathway of Entamoeba histolytica: characterization and expression of the ERD2 gene.
Archives of Medical Research,
28 (Spec No:59-61.),
59-61.
Artículo
187 - Estrada,G., Colin,L., Gaytan,P., Alagon,A., Lizardi,P.M. (1996). Sequence-specific detection of PCR-amplified DNA by restriction enzyme release of hybrids.
Molecular and cellular probes,
10 (3),
179-185.
Artículo
188 - Miranda,R., Salgado,L.M., Sanchez-Lopez,R., Alagon,A., Lizardi,P.M. (1996). Identification and analysis of the u6 small nuclear RNA gene from Entamoeba histolytica.
Gene,
180 (1-2),
37-42.
Artículo
189 - Ortega-Pierres,G., Alagon,A., Cortes,A., Olvera,F., Olvera,A., Gonzalez,A., Lizardi,P., Berzunza-Cruz,M., Saavedra-Lira,E., Perez-Montfort,R., Velasco-Castrejon,O., Sotero-Delgado Dominguez,I., Becker,I., Hernandez,R., Martinez-Calvillo,S., Frixione,E., Ruiz,L., Santillan,M., Vega,L., Tejero,J.M., Undeen,A.H., Kretschmer,R.R., Herion,P., Saavedra,R., Yepez-Mulia,L. (1996). [Impact of new methodologies in the study of parasites].
Gaceta Medica de Mexico,
132 (5),
475-517.
Artículo
190 - Michel,B., Lizardi,P.M., Alagon,A., Zurita,M. (1995). Identification and analysis of the start site of ribosomal RNA transcription of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
73 (1-2),
19-30.
Artículo
191 - Noeske-Jungblut,C., Haendler,B., Donner,P., Alagon,A., Possani,L., Schleuning,W.D. (1995). Triabin, a highly potent exosite inhibitor of thrombin.
Journal of Biological Chemistry,
270 (48),
28629-28634.
Artículo
192 - Noeske-Jungblut,C., Kratzschmar,J., Haendler,B., Alagon,A., Possani,L., Verhallen,P., Donner,P., Schleuning,W.D. (1994). An inhibitor of collagen-induced platelet aggregation from the saliva of Triatoma pallidipennis.
Journal of Biological Chemistry,
269 (7),
5050-5053.
Artículo
193 - Palmeros,B., Guereca,L., Alagon,A., Soberon-Chavez,G. (1994). Biochemical characterization of the lipolytic activity of pseudomonas aeruginosa IGB 83.
Process Biochemistry,
29 (3),
207-212.
Artículo
194 - Cevallos,M.A., Porta,H., Alagon,A.C., Lizardi,P.M. (1993). Sequence of the 5.8S ribosomal gene of pathogenic and non-pathogenic isolates of Entamoeba histolytica.
Nucleic Acids Research,
21 (2),
355-355.
Note
195 - Cevallos,M.A., Navarro-Duque,C., Varela-Julia,M., Alagon,A.C. (1992). Molecular mass determination and assay of venom hyaluronidases by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Toxicon,
30 (8),
925-930.
Note
196 - Michel,B., Alagon,A., Lizardi,P.M., Zurita,M. (1992). Characterization of a repetitive DNA element from Entamoeba histolytica.
Molecular and Biochemical Parasitology,
51 (1),
165-168.
Artículo
197 - Possani,L.D., Fletcher,P.L., Fletcher,M.D., Rode,G.S., Mochca-Morales,J., Lucas,S., Coronas,F.V., Alagon,A.C., Martin,B.M. (1992). Structural and functional characteristics of toxins purified from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello.
Memorias do Instituto Butantan,
54 (2),
35-52.
Artículo
198 - Schleuning,W.D., Alagon,A., Boidol,W., Bringmann,P., Petri,T., Kratzschmar,J., Haendler,B., Langer,G., Baldus,B., Witt,W. (1992). Plasminogen activators from the saliva of Desmodus rotundus (common vampire bat): unique fibrin specificity.
Annals of the New York Academy of Sciences,
667,
395-403.
*
Artículo
199 - Kratzschmar,J., Haendler,B., Langer,G., Boidol,W., Bringmann,P., Alagon,A., Donner,P., Schleuning,W.D. (1991). The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression.
Gene,
105 (2),
229-237.
Note
200 - Vargas-Villarreal,J., Martin-Polo,J.J., Reynaud,E., Alagon,A.C. (1991). A new affinity adsorbent for the purification of phospholipases A1 and A2 from animal venoms.
Toxicon,
29 (1),
119-124.
Artículo
201 - Zurita,M., Alagon,A., Vargas-Villarreal,J., Lizardi,P.M. (1991). The Entamoeba histolytica rDNA episome: nuclear localization, DNAase I sensitivity map, and specific DNA-protein interactions.
Molecular Microbiology,
5 (8),
1843-1851.
Note
202 - Laclette,J.P., Alagon,A., Willms,K., Torre-Blanco,A. (1990). Purification of antigen B from Taenia solium cysticerci by affinity to mammalian collagen.
Journal of Parasitology,
76 (2),
273-275.
Artículo
203 - Alagon,A.C., Guzman,H.S., Martin,B.M., Ramirez,A.N., Carbone,E., Possani,L.D. (1988). Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch.
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology,
89 (1),
153-161.
Artículo
204 - Alagon,A., Possani,L.D., Smart,J., Schleuning,W.D. (1986). Helodermatine, a kallikrein-like, hypotensive enzyme from the venom of Heloderma horridum horridum (Mexican beaded lizard).
Journal of Experimental Medicine,
164 (6),
1835-1845.
Artículo
205 - Sosa,B.P., Alagon,A.C., Martin,B.M., Possani,L.D. (1986). Biochemical characterization of the phospholipase A2 purified from the venom of the Mexican beaded lizard (Heloderma horridum horridum Wiegmann).
Biochemistry,
25 (10),
2927-2933.
*
Artículo
206 - King,T.P., Alagon,A.C., Kuan,J., Sobotka,A.K., Lichtenstein,L.M. (1983). Immunochemical studies of yellowjacket venom proteins.
Molecular Immunology,
20 (3),
297-308.
*
Artículo
207 - Alagon,A.C., Maldonado,M.E., Julia,J.Z., Sanchez,C.R., Possani,L.D. (1982). Venom from two sub-species of Heloderma horridum (Mexican beaded lizard): general characterization and purification of N-benzoyl-L-arginine ethyl ester hydrolase.
Toxicon,
20 (2),
463-475.
*
Artículo
208 - King,T.P., Alagon,A., Kochoumian,L., Kuan,J., Sobotka,A., Lichtenstein,L.M. (1981). Limited proteolysis of antigens E and K from ragweed pollen.
Archives of Biochemistry and Biophysics,
212 (1),
127-135.
*
Artículo
209 - Possani,L., Steinmetz,W.E., Dent,M.A., Alagon,A.C., Wuthrich,K. (1981). Preliminary spectroscopic characterization of six toxins from Latin American scorpions.
Biochimica et Biophysica Acta (BBA) - Protein Structure,
669 (2),
183-192.
*
Artículo
210 - Alagon,A.C., King,T.P. (1980). Activation of polysaccharides with 2-iminothiolane and its uses.
Biochemistry,
19 (18),
4341-4345.
*
Artículo
211 - Alagon,A.C., Molinar,R.R., Possani,L.D., Fletcher,P.L., Cronan,J.E., Julia,J.Z. (1980). Venom from the snake Bothrops asper Garman. Purification and characterization of three phospholipases A2.
Biochemical Journal,
185 (3),
695-704.
*
Artículo
212 - Possani,L.D., Fletcher,P.L., Alagon,A.B., Alagon,A.C., Julia,J.Z. (1980). Purification and characterization of a mammalian toxin from venom of the Mexican scorpion, Centruroides limpidus tecomanus Hoffmann.
Toxicon,
18 (2),
175-183.
*
Note
213 - Possani,L.D., Sosa,B.P., Alagon,A.C., Burchfield,P.M. (1980). The venom from the snakes Agkistrodon bilineatus Taylori and Crotalus durissus Totonacus: lethality, biochemical and immunological properties.
Toxicon,
18 (3),
356-360.
*
Artículo
214 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Varela,M.J., Julia,J.Z. (1979). Purification and characterization of a phospholipase A2 from the venom of the coral snake, Micrurus fulvius microgalbineus (Brown and Smith).
Biochemical Journal,
179 (3),
603-606.
*
Artículo
215 - Sosa,B.P., Alagon,A.C., Possani,L.D., Julia,J.Z. (1979). Comparison of phospholipase activity with direct and indirect lytic effects of animal venoms upon human red cells.
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry,
64 (2),
231-234.
*
Artículo
216 - King,T.P., Sobotka,A.K., Alagon,A., Kochoumian,L., Lichtenstein,L.M. (1978). Protein allergens of white-faced hornet, yellow hornet, and yellow jacket venoms.
Biochemistry,
17 (24),
5165-5174.
*
Artículo
217 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Erickson,B.W. (1977). Purification and properties of mammalian toxins from the venom of Brazilian Scorpion Tityus serrulatus Lutz and Mello.
Archives of Biochemistry and Biophysics,
180 (2),
394-403.
*
Artículo
218 - Frenk,J., Acuna,D.L., Bobadilla,J.L., Alagon,A. (1976). [Liberal medicine and institutional medicine in Mexico].
Salud Publica de Mexico,
18 (3),
481-493.
*
Capítulo nacional
219 - Nares-Torices,M.A., Olguin-Sanchez,E., Rodrigues-Alvarez,D., Alagon-Cano,A., Sanchez-Villegas,M.C.S. (2021). Loxoscelismo. Una Mirada a la Toxinologia de Mexico.
35-58,
Ciudad de Mexico: Cognitio Journal.
Capítulo internacional
220 - Neri-Castro,E., Benard-Valle,M., Lopez de Leon,J., Boyer,L., Alagon,A. (2021). Envenomations by Reptiles in Mexico. Handbook of Venoms and Toxins of Reptiles 2a.
529-542,
2a.
Nacional
221 - Neri-Castro,E., Reyna,M.A., Alagon-Cano,A. (2021). Serpientes Venenosas. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
384-396,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
Nacional
222 - Reyna-Rojas,M.A., Neri-Castro,E.E., Alagon-Cano,A. (2021). Uso, manejo y percepción de herpetofauna en dos localidades del municipio de Tlaltizap án. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
398-411,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
Nacional
223 - Neri-Castro,E.E., Alagon-Cano,A. (2020). Reptiles venenosos: veneno y tratamiento. Biodiversidad en Morelos. Estudio de estado 2, vol 2.
306-310,
2,
Mexico: CONABIO.
Nacional
224 - Alagon,A. (2019). Biotecnología de antivenenos mexicana. Manos que sanan. Avances en la medicina potosina.
185-187,
San Luis Potosí, México: Graphstyle Publishers.
Internacional
225 - Paniagua, D., Vergara, I., Boyer, L., Alagon, A. (2017). Role of Lymphatic System on Snake Venom Absorption. Snake Venoms. Toxicology Series.
453-474,
Dordrecht.
Internacional
226 - Benard-Valle,M., Neri,E., Fry,B., Boyer,L., Cochran,C., Alam,M., Jackson,T.N.W., Paniagua,D., Sheira,D., Olvera-Rodriguez,F., Koludorov,I., Sunagar,K., Alagon,A. (2015). Antivenom research and development. Venomous reptiles and their toxins: Evolution, pathophysiology and biodiscovery .
61-72,
New York.
Internacional
227 - Boyer,L., Alagon,A., Fry,B.G., Jackson,T.N.W., Sunagar,K., Chippaux,J.P. (2015). Signs, symptoms and treatment of envenomation. Venomous Reptiles and Their Toxins: Evolution, Pathophysiology and Biodiscovery.
32-60,
New York: Oxford University Press.
Internacional
228 - Paniagua,D., Vergara,I., Boyer,L., Alagon,A. (2015). Role of Lymphatic System on Snake Venom Absorption. Snake Venoms.
Toxinology,
1-19.
Nacional
229 - Alagon,A., Odell,G. (2011). La biologia y taxonomia de las aranas americanas. Emergencias por Animales Ponzonosos en las Americas .
181-201,
Mexico: Instituto Bioclon & Laboratorios Silanes.
Nacional
230 - Alagon,A., Possani,L.D. (2003). Desarrollo de nuevos f rmacos a partir de la fauna tropical. Fronteras de la Biología en los Inicios del Siglo XXI, Módulo VII .
123-160,
Mexico,D.F..
Nacional
231 - Estrada,G., Sanchez,R., Lizardi,P.M., Alagon,A. (1998). Entamoeba histolytica y la reaccion en cadena de polimerasa por hibridazion y liberacion enzimatica (PCR-HERA). Biologia molecular en medicina.
Coleccion de textos politecnicos, series biotecnologicas.,
47-60,
Mexico DF.
Internacional
232 - Dehesa-Davila,M., Alagon,A.C., Possani,L.D. (1995). Clinical toxicology of scorpion stings. Handbook of clinical toxicology of animal venoms and poisons.
221-238,
New York.
Nacional
233 - Alagon,A., Carillo,C., Chavez-Haro,A., De la Mora-Zerpa,C., Larralde,C., Lamas,N, Martin,E, Osnaya-Romero,N., Perez,Y, Possani,L.D., Romero-Zamora,L. (2003). Práctica Médica Efectiva- Alacranismo (T63.2, X22).
Mexico.
Nacional divulgacion
234 - Alagon Cano,A. (2023). Antivenenos contra animales ponzoñosos: una historia de aventuras científicas y de éxitos para México.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
9 (32).
Nacional Case report
235 - Madrigal-Anaya,J.C., Cruz-Ibarra,A., Rodriguez-Uvalle,N.C., Gil-Alarcon,G., Alagon,A., Rodriguez-Flores,G., Boyer,L., Neri-Castro,E. (2022). A case of exotic envenomation by Naja kaouthia in Mexico.
Latin American Journal of Clinical Sciences and Medical Technology,
4,
1-8.
nacional divulgación
236 - Neri-Castro,E., Alagon-Cano,A. (2021). Descubrimientos recientes: Venenos de serpientes.
Hypatia,
66.
nacional divulgacion
Nacional Editorial
238 - Neri-Castro,E.E., Benard-Valle,M., Gil,J., Lopez de Leon J., Borja,M., Alagon,A. (2020). Serpientes venenosas en México: una revisión al estudio de los venenos, los antivenenos y la epidemiología .
Revista Latinoamericana de Herpetologia,
3 (2),
5-22.
Preprint
239 - Montes-Grajales,D., Jimenez,B., Rogel,M.A., Alagon,A., Esturau-Escofet,N., Esquivel,B., Martinez-Romero,J., Martinez-Romero,E. (2019). Nitrogen-fixing Klebsiella variicola in feces from herbivorous tortoises.
bioRxiv,
Preprint posted June 10, 2019,
666818.
Divulgación
240 - Reyna-Rojas,M.A., Garcia-Flores,A., Neri-Castro,E., Alagon-Cano,A., Monroy-Martinez,R. (2015). Conocimiento etnoherpetológico de dos comunidades aledañas a la reserva estatal sierra de montenegro, Morelos, Mexico.
Etnobiologia,
13 (2),
37-48.
Divulgación
241 - Corzo-Burguete,G., Alagon-Cano,A., Clement-Carretero,H., Jurado-Reyes,S.M., Herrera-Herrera,E. (2014). Los venenos de tar ntulas y la absorción de medicinas en nuestro cuerpo.
Hypatia,
48 (2).
Divulgación
242 - Neri-Castro,E., Benard-Valle,M., Alagon-Cano,A. (2014). Reptiles venenosos en M?xico.
Revista Digital Universitaria,
15 (11),
art 86.
Divulgación
Divulgación
244 - Alagon-Cano,A., Corzo,G., Clement-Carretero,H., Garcia-Garcia,F. (2010). Arañas: venenos con potencial biotecnológico.
Hypatia,
33.
Divulgación
245 - Rodriguez,M., Prud`Homme,M., Alagon,A., Stock,R. (2009). Expresión de a-latrotoxina Recombinante Activa de Latrodectus mactans Utilizando el Sistema de Células de Insecto-Baculovirus.
BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria,
13 (2),
34-47.
Nacional
246 - Mata-Gonzalez,M.T., Garcia-Ubbelohde,W., Alagon-Cano,A., Paniagua-Solis,J. (2008). Anticuerpos monoclonales para uso terap?utico en humanos.
Informaceutico Mexico,
15 (9-10),
30-36.
Nacional
247 - Rendon-Anaya,M., Alagon,A. (2008). Mecanismos moleculares de diversificación de inmunoglobulinas.
Revista de Educación Bioquímica,
27 (1),
19-29.
Biographical-Item
248 - Alagon,A., Clement-Carretero,H., Lomonte,B., Gutierrez,J.M., Ownby,C.L. (2007). Obituary of George V. Odell, 1926-2006.
Toxicon,
49 (6),
886-887.
Divulgación
249 - Olvera-Rodriguez,A., Alagon-Cano,A., Ramos-Cerrillo,B., Cardoso-Torres,H.M., Olvera-Rodriguez,F. (2007). La partitura de la araña violinista: Envenenamiento fatal.
Hypatia,
22.
Editorial Material
250 - Stock,R.P., Massougbodji,A., Alagon,A., Chippaux,J.P. (2007). Bringing antivenoms to Sub-Saharan Africa.
Nature Biotechnology,
25 (2),
173-177.
News Item
251 - Chippaux,J.P., Stock,R.P., Alagon,A. (2005). Report of the 2nd international conference on envenomations in Africa (Deuxieme colloque international sur les envenomations en Afrique).
Toxicon,
46 (1),
115-118.
Divulgación
Divulgación
Divulgación
254 - Alagon,A. (2002). Anticuerpos seguros y eficaces: la revoluacion de los nuevos antivenenos.
Revista Universidad de Mexico,
617.
Divulgación
Divulgación
256 - Ramos,M.A., Alagon,A. (2001). Ruta secretoria y Entamoeba histolytica.
Mensaje Bioquimico,
25,
111-128.
Nacional
257 - Estrada-Galvan,B., Scheinvar,L., Alagon,A., Olalde-Parra,G. (2000). Resultados preliminares de electroforesis en proteínas como método auxiliar en la taxonomía de Opuntia spp.
Acta Cientifica Potosina,
15 (1),
7-24.
Nacional
Nacional
259 - Arauco,R., Alagon,A. (1979). [Propanolol in arterial hypertension. Beta-blockaders. Recent advances].
Prensa médica mexicana,
44 (5-6),
97-104.
*
260 - Alagon Cano, Alejandro (1988). Enzimas hidroliticas del veneno de heloderma horridum horridum : fosfolipasa A2 y calicreina .
Doctorado en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
261 - Alagon Cano, Alejandro (1980). Estudio sobre los venenos de varias especies zoologicas.
Instituto de Investigacions Biomedicas,
Maestria en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
Artículo in press
262 - Alfaro-Chinchilla,A., Lomonte,B., Zuniga,L., Acevedo,M., Neri-Castro,E., Alagon,A., Bonilla,F., Diaz,C., Sasa,M.. Venom composition, toxicity and cross-neutralization by PoliVal-ICP antivenom, of Mesoamerican jumping pitvipers genus Metlapilcoatlus (Viperidae: Crotalinae).
Transactions of the Royal Society of Tropical Medicine and Hygiene,
Advance access,
trae120.
Artículo
263 - Borja,M., Castaneda-Gaytan,G., Alagon,A., Strickland,J.L., Parkinson,C., Gutierrez-Martinez,A., Rodriguez-Lopez,B., Zarzosa,V., Lomonte,B., Saviola,A.J., Fernandez,J., Smith,C.F., Hansen,K.C., Perez-Robles,A., Castaneda-Perez,S., Hirst,S.R., Olvera-Rodriguez,F, Fernandez-Badillo,L, Sigala,J, Jones,J, Montano-Rubalcava,C, Ramirez-Chaparro,R., Margres,M., Acosta-Campana,G., Neri-Castro,E.. Venom variation and ontogenetic changes in the Crotalus molossus complex: Insights into composition, activities, and antivenom neutralization.
Comparative Biochemistry and Physiology - C Toxicology and Pharmacology,
290,
110129.
Artículo
264 - Damsbo,A., Benard-Valle,M., Jansen,T., Burlet,N.J., Overath,M.D., Guadarrama-Martinez,A., Boddum,K., Alagon,A., Rivera-de-Torre,E., Laustsen,A.H.. Discovery of broadly neutralizing V(H)Hs against short-chain a-neurotoxins using a consensus toxin as an antigen.
MAbs,
17 (1),
2522838.
Artículo
265 - Damsbo,A., Burlet,N.J., Fernandez-Quintero,M.L., Benard-Valle,M., Overath,M.D., Guadarrama-Martinez,A., Vlamynck,A., Bisbo,I., Villalobos,C., Tulika,T., Alagon,A., Loeffler,J.R., Ward,A.B., Boddum,K., Morth,J.P., Rivera-de-Torre,E., Laustsen,A.H.. Structural mechanisms behind the neutralisation of long-chain a-neurotoxins by broadly neutralising V(H)Hs discovered using a consensus antigen.
Communications Chemistry,
8 (1),
209.
Artículo in press
266 - Seneci,L., Chandrasekara,U., Chowdhury,A., Zarzosa,V., Guadarrama-Martinez,A., Neri-Castro,E., Alagon,A., Soria,R., Fry,B.G.. The X Factor: Regional differences in the level of ontogenetic variations in procoagulant venom activity in the Northwestern Neotropical Rattlesnake (Crotalus culminatus).
Biochimie,
Jul 16 [Online ahead of print].
Artículo
267 - Zarzosa,V., Neri-Castro,E., Lomonte,B., Fernandez,J., Rodriguez-Barrera,G., Rodriguez,B., Rodriguez-Solis,A.M., Olvera-Rodriguez,A., Benard-Valle,M., Saviola,A., Garcia-Vazquez,U.O., Fernandez-Badillo,L, Morales-Capellan,N., Borja,M., Zamudio,F., Alagon,A.. Integrative transcriptomic, proteomic, biochemical and neutralization studies on the venom of Micrurus ephippifer.
Journal of Proteomics,
316,
105416.
Artículo
268 - Benard-Valle,M., Wouters,Y., Ljungars,A., Nguyen,G.T.T., Ahmadi,S., Ebersole,T.W., Dahl,C.H., Guadarrama-Martinez,A., Jeppesen,F., Eriksen,H., Rodriguez-Barrera,G., Boddum,K., Jenkins,T.P., Bjorn,S.P., Schoffelen,S., Voldborg,B.G., Alagon,A., Laustsen,A.H.. In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model.
Nature Communications,
15 (1),
4310.
Artículo
269 - Bourke,L.A., Zdenek,C.N., Huynh,T.M., Hodgson,W.C., Alagon,A., Castro,E.N., Jones,J., Fry,B.G.. Fangs and Foliage: Unearthing the Haemotoxic Secrets of Cannabis-Dwelling Rattlesnakes.
Toxicon,
244,
107756.
Artículo
270 - Campbell,S.I.D., Chow,C.Y., Neri-Castro,E., Alagon,A., Gomez,A., Soria,R., King,G.F., Fry,B.G.. Taking the sting out of scorpions: Electrophysiological investigation of the relative efficacy of three antivenoms against medically significant Centruroides species.
Comparative Biochemistry and Physiology C Toxicology and Pharmacology,
283,
109977.
Artículo
271 - Dashevsky,D., Harris,R.J., Zdenek,C.N., Benard-Valle,M., Alagon,A., Portes-Junior,J.A., Tanaka-Azevedo,A.M., Grego,K.F., Sant'Anna,S.S., Frank,N., Fry,B.G.. Red-on-Yellow Queen: Bio-Layer Interferometry Reveals Functional Diversity Within Micrurus Venoms and Toxin Resistance in Prey Species.
Journal of Molecular Evolution,
92,
317-328.
Artículo
272 - Guadarrama-Martinez,A., Neri-Castro,E., Boyer,L., Alagon,A.. Variability in antivenom neutralization of Mexican viperid snake venoms.
PLoS Neglected Tropical Diseases,
18 (5),
e0012152.
Artículo
273 - Neri-Castro,E., Zarzosa,V., Benard-Valle,M., Rodriguez-Solis,A.M., Hernandez-Orihuela,L., Ortiz-Medina,J.A., Alagon,A.. Quantifying venom production: A study on Micrurus snakes in Mexico.
Toxicon,
240,
107658.
Artículo
274 - Neri-Castro,E., Zarzosa,V., Lomonte,B., Zamudio,F., Hernandez-Orihuela,L., Olvera-Rodriguez,A., Rodriguez-Solis,A.M., Borja,M., Garcia-Vazquez,U.O., Jones,J.M., Parkinson,C.L., Alagon,A.. Exploring Venom Diversity in Mixcoatlus browni and Mixcoatlus barbouri: A Comparative Analysis of Two Rare Mexican Snake Species with Crotoxin-like Presence.
Biochimie,
225,
81-88.
Artículo
275 - Olivares-Hernandez,R., Riano-Umbarila,L., Becerril,B., Alagon-Cano,A., Vazquez-Lopez,H.. Pharmacokinetic evaluation of a single chain antibody fragment against scorpion toxins in sheep.
Toxicon,
242,
107691.
Artículo
276 - Valdez-Cruz,N.A., Rosiles-Becerril,D., Martinez-Olivares,C.E., Garcia-Hernandez,E., Cobos-Marin,L., Garzon,D., Lopez-Salas,F.E., Zavala,G., Luviano,A., Olvera,A., Alagon,A., Ramirez,O.T., Trujillo-Roldan,M.A. Oral administration of a recombinant modified RBD antigen of SARS-CoV-2 as a possible immunostimulant for the care of COVID-19.
Microbial Cell Factories,
23 (1),
41.
Artículo
277 - Zarzosa,V., Lomonte,B., Zamudio,F., Ponce-Lopez,R., Olvera-Rodriguez,F., Borja,M., Alagon,A., Neri-Castro,E.. Venom of the neotropical rattlesnake, Crotalus culminatus: Intraspecific variation, neutralization by antivenoms, and immunogenicity in rabbits.
Biochimie,
216,
160-174.
Artículo
278 - Borja,M., Neri-Castro,E., Gutierrez-Martinez,A., Bledsoe,R., Zarzosa,V., Rodriguez-Lopez,B., Strickland,J.L., Becerra-Lopez,J., Valenzuela-Ceballos,S., Parkinson,C.L., Alagon,A., Castaneda-Gaytan,G.. Ontogenetic change in the venom composition of one Mexican black-tailed rattlesnake (Crotalus molossus nigrescens) from Durango, Mexico.
Toxicon,
24,
107280.
Artículo
279 - Perez-Juarez,H., Serrano-Vazquez,A., Godinez-Alvarez,H., Gonzalez,E., Rojas-Velazquez,L., Moran,P., Portillo-Bobadilla,T., Ramiro,M., Hernandez,E., Lau,C., Martinez,M., Padilla,M.L.A., Zaragoza,M.E., Taboada,B., Palomares,L.A., Lopez,S., Alagon,A., Arias,C.F., Ximenez,C.. Longitudinal anti-SARS-CoV-2 antibody immune response in acute and convalescent patients.
Frontiers in Cellular and Infection Microbiology,
13,
1239700.
Artículo
280 - Siegrist,A.A., Boyer,L., Balchan,N.R., Vazquez,H., Alagon,A., de Roodt,A., Craig,I.S., Poulin,I.S., Timmerman,A., Trocola,D.. Outcomes of treatment of snake and scorpion envenomation in birds of prey, with and without antivenom.
Journal of Zoo and Wildlife Medicine,
53 (4),
870-881.
Nacional divulgacion
281 - Alagon Cano,A.. Antivenenos contra animales ponzoñosos: una historia de aventuras científicas y de éxitos para México.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
9 (32).
Artículo
282 - Colis-Torres,A., Neri-Castro,E., Strickland,J.L., Olvera-Rodriguez,A., Borja,M., Calvete,J., Jones,J., Parkinson,C.L., Banuelos,J., Lopez de Leon,J., Alagon,A.. Intraspecific venom variation of Mexican West Coast Rattlesnakes (Crotalus basiliscus) and its implications for antivenom production.
Biochimie,
192,
114-124.
Artículo
283 - Neri-Castro,E., Strickland,J.L., Carbajal-Marquez,R.A., Zuniga,J., Ponce-Lopez,R., Olvera,F., Alagon,A.. Characterization of the venom and external morphology of a natural hybrid between Crotalus atrox and Crotalus mictlantecuhtli.
Toxicon,
207,
43-47.
Artículo
284 - Neri-Castro,E., Zarzosa,V., Colis-Torres,A., Fry,B.G., Olvera-Rodriguez,A., Jones,J., Reyes-Velazquez,J., Zamudio,F., Borja,M., Alagon,A., Lomonte,B.. Proteomic and toxicological characterization of the venoms of the most enigmatic group of rattlesnakes: The long-tailed rattlesnakes.
Biochimie,
202,
226-236.
Artículo
285 - Olvera-Rodriguez,A., Amaro-Ruiz,M.G., Benard-Valle,M., Neri-Castro,E., Olvera-Rodriguez,F., Alagon,A.. Neutralization of black widow spider (Latrodectus mactans) venom with rabbit polyclonal serum hyperimmunized with recombinant alpha-latrotoxin fragments.
Biochimie,
201,
55-62.
Artículo
286 - Youngman,N.J., Carlsson,D.J., Jones,L., Neri-Castro,E., Alagon,A., Fry,B.G.. Cloud serpent coagulotoxicity: The biochemical mechanisms underpinning the anticoagulant actions of Mixcoatlus and Ophryacus venoms.
Toxicon,
211,
44-49.
Nacional Case report
287 - Madrigal-Anaya,J.C., Cruz-Ibarra,A., Rodriguez-Uvalle,N.C., Gil-Alarcon,G., Alagon,A., Rodriguez-Flores,G., Boyer,L., Neri-Castro,E.. A case of exotic envenomation by Naja kaouthia in Mexico.
Latin American Journal of Clinical Sciences and Medical Technology,
4,
1-8.
Artículo
288 - Archundia,I.G., de la Rosa,G., Olvera,F., Calderon,A., Benard-Valle,M., Alagon,A., Corzo,G.. Assessment of neutralization of Micrurus venoms with a blend of anti-Micrurus tener and anti-ScNtx antibodies.
Vaccine,
39 (6),
1000-1006.
Artículo
289 - Benard-Valle, M., Neri-Castro, E., Elizalde-Morales, N., Olvera-Rodriguez, A., Strickland, J., Acosta, G., Alagon, A.. Protein composition and biochemical characterization of venom from Sonoran Coral Snakes (Micruroides euryxanthus).
Biochimie,
182,
206-216.
Artículo
290 - Bourke, L. A., Zdenek, C. N., Neri-Castro, E., Benard-Valle, M., Alagon, A., Gutierrez, J. M., Sanchez, E. F., Aldridge, M., Fry, B. G.. Pan-American Lancehead Pit-Vipers: Coagulotoxic Venom Effects and Antivenom Neutralisation of Bothrops asper and B. atrox Geographical Variants.
Toxins (Basel),
13 (2),
78.
Artículo
291 - Dashevsky,D., Benard-Valle,M., Neri-Castro,E., Youngman,N.J., Zdenek,C.N., Alagon,A., Portes-Junior,J.A., Frank,N., Fry,B.G.. Anticoagulant Micrurus venoms: targets and neutralization.
Toxicology Letters,
337,
91-97.
Artículo
292 - de Roodt,A.R., Lanari,L.C., Ramirez,J.E., Gomez,C., Barragan,J., Litwin,S., van Grootheest,J.H., Desio,M., Dokmetjian,J.C., Dolab,J.A., Damin,C.F., Alagon,A.. Cross-reactivity of some micrurus venoms against experimental and therapeutic anti-micrurus antivenoms.
Toxicon,
200,
153-164.
Artículo
293 - Franco-Servin,C., Neri-Castro,E., Benard-Valle,M., Alagon,A., Rosales-Garcia,R.A., Guerrero-Alba,R., Poblano-Sanchez,J.E., Silva-Briano,M., Guerrero-Barrera,A.L., Sigala-Rodriguez,J.J.. Biological and Biochemical Characterization of Coronado Island Rattlesnake (Crotalus helleri caliginis) Venom and Antivenom Neutralization.
Toxins (Basel),
13 (8),
582.
Artículo
294 - Ponce-Lopez,R., Neri-Castro,E., Olvera-Rodriguez,F., Sanchez,E.E., Alagon,A., Olvera-Rodriguez,A.. Neutralization of crotamine by polyclonal antibodies generated against two whole rattlesnake venoms and a novel recombinant fusion protein.
Toxicon,
197,
70-78.
Artículo
295 - Rodrigues,C.F.B., Zdenek,C.N., Serino-Silva,C., de Morais-Zani,K., Grego,K.F., Benard-Valle,M., Neri-Castro,E., Alagon,A., Tanaka-Azevedo,A.M., Fry,B.G.. Boa g PLI from Boa constrictor Blood is a Broad-Spectrum Inhibitor of Venom PLA(2) Pathophysiological Actions.
Journal of Chemical Ecology,
47,
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296 - Seneci,L., Zdenek,C.N., Chowdhury,A., Rodrigues,C.F.B., Neri-Castro,E., Benard-Valle,M., Alagon,A., Fry,B.G.. A Clot Twist: Extreme Variation in Coagulotoxicity Mechanisms in Mexican Neotropical Rattlesnake Venoms.
Frontiers in Immunology,
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297 - Seneci,L., Zdenek,C.N., Bourke,L.A., Cochran,C., Sanchez,E.E., Neri-Castro,E., Benard-Valle,M., Alagon,A., Frank,N., Fry,B.G.. A symphony of destruction: Dynamic differential fibrinogenolytic toxicity by rattlesnake (Crotalus and Sistrurus) venoms.
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology,
245,
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Capítulo nacional
298 - Nares-Torices,M.A., Olguin-Sanchez,E., Rodrigues-Alvarez,D., Alagon-Cano,A., Sanchez-Villegas,M.C.S.. Loxoscelismo. Una Mirada a la Toxinologia de Mexico.
35-58,
Ciudad de Mexico: Cognitio Journal.
Capítulo internacional
299 - Neri-Castro,E., Benard-Valle,M., Lopez de Leon,J., Boyer,L., Alagon,A.. Envenomations by Reptiles in Mexico. Handbook of Venoms and Toxins of Reptiles 2a.
529-542,
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300 - Neri-Castro,E., Reyna,M.A., Alagon-Cano,A.. Serpientes Venenosas. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
384-396,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
Nacional
301 - Reyna-Rojas,M.A., Neri-Castro,E.E., Alagon-Cano,A.. Uso, manejo y percepción de herpetofauna en dos localidades del municipio de Tlaltizap án. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
398-411,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
nacional divulgación
302 - Neri-Castro,E., Alagon-Cano,A.. Descubrimientos recientes: Venenos de serpientes.
Hypatia,
66.
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Artículo
304 - Benard-Valle,M., Neri-Castro,E.E., Yanez-Mendoza,M.F., Lomonte,B., Olvera,A., Zamudio,F., Restano-Cassulini,R., Possani,L.D., Jimenez-Ferrer,E., Alagon,A.. Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: Identification of the first lethal multimeric neurotoxin in coral snake venom.
Journal of Proteomics,
225,
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Artículo
305 - Braga,J.R.M., Jorge,A.R.C., Marinho,A.D., de Moraes Silveira,J.A., Nogueira-Junior,F.A., Benard-Valle,M., Alagon,A., de Menezes,R.R.P.P., Martins,A.M.C., Feijao,L.X., Monteiro,H.S.A., Jorge,R.J.B.. Renal effects of venoms of Mexican coral snakes Micrurus browni and Micrurus laticollaris.
Toxicon,
181,
45-52.
Artículo
306 - Chippaux,J.P., Celis,A., Boyer,L., Alagon,A.. Factors involved in the resilience of incidence and decrease of mortality from scorpion stings in Mexico.
Toxicon,
188,
65-75.
Artículo
307 - Garcia-Osorio,B., Lomonte,B., Benard-Valle,M., Lopez de Leon J., Roman-Dominguez,L., Mejia-Dominguez,N., Lara-Hernandez,F., Alagon,A., Neri-Castro,E.. Ontogenetic changes in the venom of Metlapilcoatlus nummifer, the Mexican jumping viper.
Toxicon,
184,
204-214.
Artículo
308 - Grashof,D., Zdenek,C.N., Dobson,J.S., Youngman,N.J., Coimbra,F., Benard-Valle,M., Alagon,A., Fry,B.G.. A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms.
Toxins (Basel),
12 (2).
Artículo
309 - Neri-Castro,E., Sanz,L., Olvera-Rodriguez,A., Benard-Valle,M., Alagon,A., Calvete,J.J.. Venomics and biochemical analysis of the black-tailed horned pitviper, Mixcoatlus melanurus, and characterization of Melanurutoxin, a novel crotoxin homolog.
Journal of Proteomics,
225,
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310 - Neri-Castro,E., Benard-Valle,M., Paniagua,D., Boyer,L.V., Possani,D., Lopez-Casillas,F., Olvera,A., Romero,C., Zamudio,F., Alagon,A.. Neotropical Rattlesnake (Crotalus simus) Venom Pharmacokinetics in Lymph and Blood Using an Ovine Model.
Toxins (Basel),
12 (7),
455.
Artículo
311 - Paniagua,D., Crowns,K., Montonera,M., Wertheimer,A., Alagon,A., Boyer,L.. Postmortem histopathology and detection of venom by ELISA following suicide by cobra (Naja kaouthia) envenomation.
Forensic Toxicology,
38 (2),
523-528.
Artículo
312 - Ponce-Lopez,R., Neri-Castro,E., Borja,M., Strickland,J.L., Alagon,A.. Neutralizing potency and immunochemical evaluation of an anti-Crotalus mictlantecuhtli experimental serum.
Toxicon,
187,
171-180.
Artículo
313 - Rivas-Mercado E., Neri-Castro E., Benard-Valle M., Rucavado-Romero,A., Olvera-Rodriguez A., Zamudio-Zuniga F., Alagon,A., Garza-Ocanas L.. Disintegrins extracted from totonacan rattlesnake (Crotalus totonacus) venom and their anti-adhesive and anti-migration effects on MDA-MB-231 and HMEC-1 cells.
Toxicology in Vitro,
65,
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Artículo
314 - Sanchez,M., Solano,G., Vargas,M., Reta-Mares,F., Neri-Castro,E., Alagon,A., Sanchez,A., Villalta,M., Leon,G., Segura,A.. Toxicological profile of medically relevant Crotalus species from Mexico and their neutralization by a Crotalus basiliscus/Bothrops asper antivenom.
Toxicon,
179,
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Nacional
315 - Neri-Castro,E.E., Alagon-Cano,A.. Reptiles venenosos: veneno y tratamiento. Biodiversidad en Morelos. Estudio de estado 2, vol 2.
306-310,
2,
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Nacional Editorial
316 - Neri-Castro,E.E., Benard-Valle,M., Gil,J., Lopez de Leon J., Borja,M., Alagon,A.. Serpientes venenosas en México: una revisión al estudio de los venenos, los antivenenos y la epidemiología .
Revista Latinoamericana de Herpetologia,
3 (2),
5-22.
Artículo
317 - de la Rosa,G., Olvera,F., Archundia,I.G., Lomonte,B., Alagon,A., Corzo,G.. Horse immunization with short-chain consensus a-neurotoxin generates antibodies against broad spectrum of elapid venomous species.
Nature Communications,
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3642.
Artículo
318 - Kakumanu,R., Hodgson,W.C., Ravi,R., Alagon,A., Harris,R.J., Brust,A., Alewood,P.F., Kemp-Harper,B.K., Fry,B.G.. Vampire Venom: Vasodilatory Mechanisms of Vampire Bat (Desmodus rotundus) Blood Feeding.
Toxins (Basel),
11 (1),
26.
Artículo
319 - Neri-Castro, E., Lomonte, B., Valdes, M., Ponce-Lopez, R., Benard-Valle, M., Borja, M., Strickland, J. L., Jones, J. M., Grunwald, C., Zamudio, F., Alagon, A.. Venom characterization of the three species of Ophryacus and proteomic profiling of O. sphenophrys unveils Sphenotoxin, a novel Crotoxin-like heterodimeric beta-neurotoxin.
Journal of Proteomics,
192,
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Artículo
320 - Neri-Castro,E., Hernandez-Davila,A., Olvera-Rodriguez,A., Cardoso-Torres,H., Benard-Valle,M., Bastiaans,E., Lopez-Gutierrez,O., Alagon,A.. Detection and quantification of a á-neurotoxin (crotoxin homologs) in the venom of the rattlesnakes Crotalus simus, C. culminatus and C. tzabcan from Mexico.
Toxicon X,
2,
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Artículo
321 - Paniagua,D., Vergara,I., Roman,R., Romero,C., Benard-Valle,M., Calderon,A., Jimenez,L., Bernas,M.J., Witte,M.H., Boyer,L.V., Alagon,A.. Antivenom effect on lymphatic absorption and pharmacokinetics of coral snake venom using a large animal model.
Clinical Toxicology,
57 (8),
727-734.
Artículo
322 - Roman-Dominguez,L., Neri-Castro,E., Vazquez-Lopez,H., Garcia-Osorio,B., Archundia,I.G., Ortiz-Medina,J.A., Petricevich,V.L., Alagon,A., Benard-Valle,M.. Biochemical and immunochemical characterization of venoms from snakes of the genus Agkistrodon.
Toxicon X,
4,
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Nacional
323 - Alagon,A.. Biotecnología de antivenenos mexicana. Manos que sanan. Avances en la medicina potosina.
185-187,
San Luis Potosí, México: Graphstyle Publishers.
Preprint
324 - Montes-Grajales,D., Jimenez,B., Rogel,M.A., Alagon,A., Esturau-Escofet,N., Esquivel,B., Martinez-Romero,J., Martinez-Romero,E.. Nitrogen-fixing Klebsiella variicola in feces from herbivorous tortoises.
bioRxiv,
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325 - Borja, M., Neri-Castro, E., Castaneda-Gaytan, G., Strickland, J.L., Parkinson, C.L., Castaneda-Gaytan, J., Ponce-Lopez, R., Lomonte, B., Olvera-Rodriguez, A., Alagon, A., Perez-Morales, R.. Biological and Proteolytic Variation in the Venom of Crotalus scutulatus scutulatus from Mexico.
Toxins (Basel),
10 (1),
35.
Artículo
326 - Borja,M., Neri-Castro,E., Perez-Morales,R., Strickland,J.L., Ponce-Lopez,R., Parkinson,C.L., Espinosa-Fematt,J., Saenz-Mata,J., Flores-Martinez,E., Alagon,A., Castaneda-Gaytan,G.. Ontogenetic Change in the Venom of Mexican Black-Tailed Rattlesnakes (Crotalus molossus nigrescens).
Toxins (Basel),
10 (12).
Artículo
327 - Calcines-Cruz, C., Olvera, A., Castro-Acosta, R.M., Zavala, G., Alagon, A., Trujillo-Roldan, M.A., Valdez-Cruz, N.A.. Recombinant-phospholipase A2 production and architecture of inclusion bodies are affected by pH in Escherichia coli.
International Journal of Biological Macromolecules,
108,
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Artículo
328 - Dobson, J., Yang, D., Op den, Brouw B., Cochran, C., Huynh, T., Kurrupu, S., Sanchez, E.E., Massey, D.J., Baumann, K., Jackson, T.N.W., Nouwens, A., Josh, P., Neri-Castro, E., Alagon, A., Hodgson, W.C., Fry, B.G.. Rattling the border wall: Pathophysiological implications of functional and proteomic venom variation between Mexican and US subspecies of the desert rattlesnake Crotalus scutulatus.
Comparative Biochemistry and Physiology C Toxicology and Pharmacology,
205,
62-69.
Artículo
329 - Guerrero-Garzon, J.F., Benard-Valle, M., Restano-Cassulini, R., Zamudio, F., Corzo, G., Alagon, A., Olvera-Rodriguez, A.. Cloning and sequencing of three-finger toxins from the venom glands of four Micrurus species from Mexico and heterologous expression of an alpha-neurotoxin from Micrurus diastema.
Biochimie,
147,
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Artículo
330 - de la Rosa G., Pastor, N., Alagon, A., Corzo, G.. Synthetic peptide antigens derived from long-chain alpha-neurotoxins: Immunogenicity effect against elapid venoms.
Peptides,
88,
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Artículo
331 - Durban, J., Sanz, L., Trevisan-Silva, D., Neri-Castro, E., Alagon, A., Calvete, J.J.. Integrated venomics and venom gland transcriptome analysis of juvenile and adult Mexican rattlesnakes Crotalus simus, C. tzabcan and C. culminatus revealed miRNA-modulated ontogenetic shifts.
Journal of Proteome Research,
16 (9),
3370-3390.
Artículo
332 - Hernandez-Vargas, M.J., Gil, J., Lozano, L., Pedraza-Escalona, M., Ortiz, E., Encarnacion-Guevara, S., Alagon, A., Corzo, G.. Proteomic and transcriptomic analysis of saliva components from the hematophagous reduviid Triatoma pallidipennis.
Journal of Proteomics,
162,
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Artículo
333 - Rivas, E., Neri-Castro, E., Benard-Valle, M., Hernandez-Davila, A.I., Zamudio, F., Alagon, A.. General characterization of the venoms from two species of rattlesnakes and an intergrade population (C. lepidus x aquilus) from Aguascalientes and Zacatecas, Mexico.
Toxicon,
138,
191-195.
Artículo
334 - Valdez-Cruz, N.A., Reynoso-Cereceda, G.I., Perez-Rodriguez, S., Restrepo-Pineda, S., Gonzalez-Santana, J., Olvera, A., Zavala, G., Alagon, A., Trujillo-Roldan, M.A.. Production of a recombinant phospholipase A2 in Escherichia coli using resonant acoustic mixing that improves oxygen transfer in shake flasks.
Microbial Cell Factories,
16 (1),
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Artículo
335 - Yang, D.C., Dobson, J., Cochran, C., Dashevsky, D., Arbuckle, K., Benard, M., Boyer, L., Alagon, A., Hendrikx, I., Hodgson, W.C., Fry, B.G.. The Bold and the Beautiful: a Neurotoxicity Comparison of New World Coral Snakes in the Micruroides and Micrurus Genera and Relative Neutralization by Antivenom.
Neurotoxicity Research,
32 (3),
487-495.
Internacional
336 - Paniagua, D., Vergara, I., Boyer, L., Alagon, A.. Role of Lymphatic System on Snake Venom Absorption. Snake Venoms. Toxicology Series.
453-474,
Dordrecht.
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337 - Clement,H., Flores,V., de la Rosa,G., Zamudio,F., Alagon,A., Corzo,G.. Heterologous expression, protein folding and antibody recognition of a neurotoxin from the Mexican coral snake Micrurus laticorallis.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
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Revisión
338 - Lomonte,B., Rey-Suarez,P., Fernandez,J., Sasa,M., Pla,D., Vargas,N., Benard-Valle,M., Sanz,L., Correa-Netto,C., Nunez,V., Alape-Giron,A., Alagon,A., Gutierrez,J.M., Calvete,J.J.. Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses.
Toxicon,
122,
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Artículo
339 - Olvera,F., Rosales,A., Olvera,A., Diaz,P., Sevcik,C., Salazar,V., Alagon,A., Hernandez,H., D'Suze,G.. An efficient approach to clone and express active Neopladine 2, an anticancer peptide from Tityus discrepans scorpion venom.
Process Biochemistry,
51 (5),
624-631.
Artículo
340 - Vergara,I., Castillo,E.Y., Romero-Pina,M.E., Torres-Viquez,I., Paniagua,D., Boyer,L.V., Alagon,A., Medina,L.A.. Biodistribution and Lymphatic Tracking of the Main Neurotoxin of Micrurus fulvius Venom by Molecular Imaging.
Toxins (Basel),
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341 - Bush,S.P., Ruha,A.M., Seifert,S.A., Morgan,D.L., Lewis,B.J., Arnold,T.C., Clark,R.F., Meggs,W.J., Toschlog,E.A., Borron,S.W., Figge,G.R., Sollee,D.R., Shirazi,F.M., Wolk,R., de Chazal,I, Quan,D., Garcia-Ubbelohde,W., Alagon,A., Gerkin,R.D., Boyer,L.V.. Comparison of F(ab') versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial.
Clinical Toxicology,
53 (1),
37-45.
Revisión
342 - Chippaux,J.P., Boyer,L.V., Alagon,A.. Post-exposure treatment of Ebola virus using passive immunotherapy: proposal for a new strategy.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
21,
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343 - Benard-Valle,M., Neri,E., Fry,B., Boyer,L., Cochran,C., Alam,M., Jackson,T.N.W., Paniagua,D., Sheira,D., Olvera-Rodriguez,F., Koludorov,I., Sunagar,K., Alagon,A.. Antivenom research and development. Venomous reptiles and their toxins: Evolution, pathophysiology and biodiscovery .
61-72,
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Internacional
344 - Boyer,L., Alagon,A., Fry,B.G., Jackson,T.N.W., Sunagar,K., Chippaux,J.P.. Signs, symptoms and treatment of envenomation. Venomous Reptiles and Their Toxins: Evolution, Pathophysiology and Biodiscovery.
32-60,
New York: Oxford University Press.
Internacional
345 - Paniagua,D., Vergara,I., Boyer,L., Alagon,A.. Role of Lymphatic System on Snake Venom Absorption. Snake Venoms.
Toxinology,
1-19.
Divulgación
346 - Reyna-Rojas,M.A., Garcia-Flores,A., Neri-Castro,E., Alagon-Cano,A., Monroy-Martinez,R.. Conocimiento etnoherpetológico de dos comunidades aledañas a la reserva estatal sierra de montenegro, Morelos, Mexico.
Etnobiologia,
13 (2),
37-48.
Artículo
347 - Benard-Valle,M., Carbajal-Saucedo,A., de Roodt,A., Lopez-Vera,E., Alagon,A.. Biochemical characterization of the venom of the coral snake Micrurus tener and comparative biological activities in the mouse and a reptile model.
Toxicon,
77,
6-15.
Artículo
348 - Borja,M., Castaneda,G., Espinosa,J., Neri,E., Carbajal,A., Clement,H., Garcia,O., Alagon,A.. Mojave Rattlesnake (Crotalus scutulatus scutulatus) with Type B Venom from Mexico.
Copeia,
2014 (1),
7-13.
Artículo
349 - Carbajal-Saucedo,A., Floriano,R.S., Belo,C.A., Olvera-Rodriguez,A., Alagon,A., Rodrigues-Simioni,L.. Neuromuscular Activity of Micrurus laticollaris (Squamata: Elapidae) Venom in Vitro.
Toxins (Basel),
6 (1),
359-370.
Artículo
350 - Castellanos-Mendoza,A., Castro-Acosta,R.M., Olvera,A., Zavala,G., Mendoza-Vera,M., Garcia-Hernandez,E., Alagon,A., Trujillo-Roldan,M.A., Valdez-Cruz,N.A.. Influence of pH control in the formation of inclusion bodies during production of recombinant sphingomyelinase-D in Escherichia coli.
Microbial Cell Factories,
13 (1),
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Artículo
351 - de Roodt,A.R., Clement,H., Dolab,J.A., Litwin,S., Hajos,S.E., Boyer,L., Alagon,A.. Protein content of antivenoms and relationship with their immunochemical reactivity and neutralization assays.
Clinical Toxicology,
52 (6),
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Artículo
352 - Diaz,P., Malave,C., Zerpa,N., Vazquez,H., D'Suze,G., Montero,Y., Castillo,C., Alagon,A., Sevcik,C.. IgY pharmacokinetics in rabbits: Implications for IgY use as antivenoms.
Toxicon,
90,
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Artículo
353 - Lanari,L.C., Olvera,A., Costa de Oliveira,V, Laskowicz,R.D., Boyer,L., Lago,N.R., Alagon,A., de Roodt,A.R.. Intraspecific differences in the immunochemical reactivity and neutralization of venom from Argentinean Bothrops (Rhinocerophis) alternatus by specific experimental antivenoms.
Toxicon,
85,
31-45 [corrigendum vol 88 p 138].
Artículo
354 - Sanchez-Villegas,M del C., Rodriguez-Alvarez,D., Ortega-Carrillo,C., Alagon-Cano,A., Zaldivar-Cervera,J., Loria-Castellanos,J., Urzua-Rodríguez,N.A.. [Systemic loxoscelism presented in a pregnant patient].
Revista Médica del Instituto Mexicano del Seguro Social,
52 (1),
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Artículo
355 - Sanchez-Villegas,M del C., Nazario-Santiago,C., Alagon-Cano,A., Merquez-Avila,G., Ramos-Cervantes,M.T., Loria-Castellanos,J.. Cunico-epidemiological characteristics of pediatric patients with poisoning by loxosceles spiders bite.
Prensa Medica Argentina,
100 (9),
605-613.
Artículo
356 - Vergara,I., Pedraza-Escalona,M., Paniagua,D., Restano-Cassulini,R., Zamudio,F., Batista,C.V., Possani,L.D., Alagon,A.. Eastern coral snake Micrurus fulvius venom toxicity in mice is mainly determined by neurotoxic phospholipases A.
Journal of Proteomics,
105,
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Divulgación
357 - Corzo-Burguete,G., Alagon-Cano,A., Clement-Carretero,H., Jurado-Reyes,S.M., Herrera-Herrera,E.. Los venenos de tar ntulas y la absorción de medicinas en nuestro cuerpo.
Hypatia,
48 (2).
Divulgación
358 - Neri-Castro,E., Benard-Valle,M., Alagon-Cano,A.. Reptiles venenosos en M?xico.
Revista Digital Universitaria,
15 (11),
art 86.
Artículo
359 - Boyer,L., Degan,J., Ruha,A.M., Mallie,J., Mangin,E., Alagon,A.. Safety of Intravenous Equine F(ab'): Insights following Clinical Trials involving 1534 Recipients of Scorpion Antivenom.
Toxicon,
76,
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Artículo
360 - Boyer,L.V., Chase,P.B., Degan,J.A., Figge,G., Buelna-Romero,A., Luchetti,C., Alagon,A.. Subacute coagulopathy in a randomized, comparative trial of Fab and F(ab') antivenoms.
Toxicon,
74,
101-108.
Artículo
361 - Boyer,L.V., Theodorou,A.T., Chase,P.B., Osnaya,N., Berg,M., Mallie,J., Carbajal,Y., de Jesus-Hernandez,T., Olvera,F., Alagon,A.. Effectiveness of Centruroides scorpion antivenom compared to historical controls.
Toxicon,
76,
377-385.
Artículo
362 - Low,D.H., Sunagar,K., Undheim,E.A., Ali,S.A., Alagon,A.C., Ruder,T., Jackson,T.N., Pineda-Gonzalez,S., King,G.F., Jones,A., Antunes,A., Fry,B.G.. Dracula's children: Molecular evolution of vampire bat venom.
Journal of Proteomics,
89C,
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Artículo
363 - Neri-Castro,E., Lomonte,B., Gutierrez,M.C., Alagon,A., Gutierrez,J.M.. Intraspecies variation in the venom of the rattlesnake Crotalus simus from Mexico: Different expression of crotoxin results in highly variable toxicity in the venoms of three subspecies.
Journal of Proteomics,
87,
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364 - Oukkache,N., Chgoury,F., Lalaoui,M., Alagon-Cano,A., Ghalim,N.. Comparison between two methods of scorpion venom milking in Morocco.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
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365 - Vazquez,H., Olvera,F., Alagon,A., Sevcik,C.. Production of anti-horse antibodies induced by IgG, F(ab') and Fab applied repeatedly to rabbits. Effect on antivenom pharmacokinetics.
Toxicon,
76,
362-369.
Divulgación
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367 - Clement,H., Olvera,A., Rodriguez,M., Zamudio,F., Palomares,L.A., Possani,L.D., Odell,G.V., Alagon,A., Sanchez-Lopez,R.. Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom.
Toxicon,
60 (7),
1223-1227.
Artículo
368 - Clement,H., Costa de Oliveira,V, Zamudio,F.Z., Lago,N.R., Valdez-Cruz,N.A., Valle,M.B., Alagon,A.C., Possani,L.D., de Roodt,A.R.. Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A(2) from Bothrops (Rhinocerophis) ammodytoides Venom.
Toxicon,
60 (7),
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Artículo
369 - Koludarov,I., Sunagar,K., Undheim,E.A., Jackson,T.N., Ruder,T., Whitehead,D., Saucedo,A.C., Mora,G.R., Alagon,A.C., King,G., Antunes,A., Fry,B.G.. Structural and Molecular Diversification of the Anguimorpha Lizard Mandibular Venom Gland System in the Arboreal Species Abronia graminea.
Journal of Molecular Evolution,
75 (5-6),
168-183.
Artículo
370 - Paniagua,D., Jimenez,L., Romero,C., Vergara,I., Calderon,A., Benard,M., Bernas,M.J., Rilo,H., de Roodt,A., D'Suze,G., Witte,M.H., Boyer,L., Alagon,A.. Lymphatic route of transport and pharmacokinetics of Micrurus fulvius (coral snake) venom in sheep.
Lymphology,
45 (4),
144-153.
Artículo
371 - Archundia,I.G., de Roodt,A.R., Ramos-Cerrillo,B., Chippaux,J.P., Olguin-Perez,L., Alagon,A., Stock,R.P.. Neutralization of Vipera and Macrovipera venoms by two experimental polyvalent antisera: A study of paraspecificity.
Toxicon,
57 (7-8),
1049-1056.
Nacional
372 - Alagon,A., Odell,G.. La biologia y taxonomia de las aranas americanas. Emergencias por Animales Ponzonosos en las Americas .
181-201,
Mexico: Instituto Bioclon & Laboratorios Silanes.
Artículo
373 - Redaelli,E., Restano-Cassulini,R., Fuentes-Silva,D., Clement,H., Schiavon,E., Zamudio,F.Z., Odell,G., Arcangeli,A., Clare,J.J., Alagon,A., Rodriguez de la Vega,R.C., Possani,L.D., Wanke,E.. Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.
Journal of Biological Chemistry,
285 (6),
4130-4142 .
Artículo
374 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics of a F(ab')(2) scorpion antivenom administered intramuscularly in healthy human volunteers.
International Immunopharmacology,
10 (11),
1318-1324.
Artículo
375 - Vazquez,H., Olvera,F., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics in rabbits and anti-sphingomyelinase D neutralizing power of Fab, F(ab')2, IgG and IgG(T) fragments from hyper immune equine plasma.
International Immunopharmacology,
10 (4),
447-454.
Divulgación
376 - Alagon-Cano,A., Corzo,G., Clement-Carretero,H., Garcia-Garcia,F.. Arañas: venenos con potencial biotecnológico.
Hypatia,
33.
Artículo
377 - Boyer,L.V., Theodorou,A.A., Berg,R.A., Mallie,J., Chavez-Mendez,A., Garcia-Ubbelohde,W., Hardiman,S., Alagon,A.. Antivenom for critically ill children with neurotoxicity from scorpion stings.
New England Journal of Medicine,
360 (20),
2090-2098 (Reply 2009 vol 361 632).
Artículo
378 - Casasola,A., Ramos-Cerrillo,B., de Roodt,A.R., Saucedo,A.C., Chippaux,J.P., Alagon,A., Stock,R.P.. Paraspecific neutralization of the venom of African species of cobra by an equine antiserum against Naja melanoleuca: A comparative study.
Toxicon,
53 (6),
602-608.
Artículo
379 - Chase,P., Boyer-Hassen,L., McNally,J., Vazquez,H.L., Theodorou,A.A., Walter,F.G., Alagon,A.. Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients.
Clinical Toxicology,
47 (1),
24-28.
Artículo
380 - Corzo,G., Bernard,C., Clement,H., Villegas,E., Bosmans,F., Tytgat,J., Possani,L.D., Darbon,H., Alagon,A.. Insecticidal peptides from the theraposid spider Brachypelma albiceps: A NMR-based model of Ba2.
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics,
1794 (8),
1190-1196.
Divulgación
381 - Rodriguez,M., Prud`Homme,M., Alagon,A., Stock,R.. Expresión de a-latrotoxina Recombinante Activa de Latrodectus mactans Utilizando el Sistema de Células de Insecto-Baculovirus.
BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria,
13 (2),
34-47.
Artículo
382 - Chippaux,J.P., Alagon,A.. [Envenomation and poisoning by venomous or poisonous animals. VII: arachnidism in the New World].
Medecine Tropicale,
68 (3),
215-221.
Artículo
383 - Corzo,G., Diego-Garcia,E., Clement,H., Peigneur,S., Odell,G., Tytgat,J., Possani,L.D., Alagon,A.. An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.
Peptides,
29 (11),
1901-1908.
Artículo
384 - Ramos-Cerrillo,B., de Roodt,A.R., Chippaux,J.P., Olguin,L., Casasola,A., Guzman,G., Paniagua-Solis,J., Alagon,A., Stock,R.P.. Characterization of a new polyvalent antivenom (Antivipmyn((R)) Africa) against African vipers and elapids.
Toxicon,
52 (8),
881-888.
Nacional
385 - Mata-Gonzalez,M.T., Garcia-Ubbelohde,W., Alagon-Cano,A., Paniagua-Solis,J.. Anticuerpos monoclonales para uso terap?utico en humanos.
Informaceutico Mexico,
15 (9-10),
30-36.
Nacional
386 - Rendon-Anaya,M., Alagon,A.. Mecanismos moleculares de diversificación de inmunoglobulinas.
Revista de Educación Bioquímica,
27 (1),
19-29.
Artículo
387 - Chippaux,J.P., Massougbodji,A., Stock,R.P., Alagon,A.. Clinical Trial of an F(ab')2 Polyvalent Equine Antivenom for African Snake Bites in Benin.
American Journal of Tropical Medicine and Hygiene,
77 (3),
538-546.
Artículo
388 - Clement,H., Odell,G., Zamudio,F.Z., Redaelli,E., Wanke,E., Alagon,A., Possani,L.D.. Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels.
Toxicon,
50 (1),
65-74.
Artículo
389 - de Roodt,A.R., Estevez-Ramirez,J., Litwin,S., Magana,P., Olvera,A., Alagon,A.. Toxicity of two North American Loxosceles (brown recluse spiders) venoms and their neutralization by antivenoms.
Clinical Toxicology,
45 (6),
678-687.
Carta
390 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R., Algaron,A., Fox,J.W.. Upregulation of IL-6, IL-8, CXCL1, and CXCL2 Dominates Gene Expression in Human Fibroblast Cells Exposed to Loxosceles reclusa Sphingomyelinase D: Insights into Spider Venom Dermonecrosis.
Journal of Investigative Dermatology,
127 (5),
1264-1266.
Carta
391 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R.P., Alagon,A., Fox,J.W.. Upregulation of cytokine expression in fibroblasts exposed to Loxosceles sphingomyelinase D: What is the trigger? - Response to Moolenaar et al.
Journal of Investigative Dermatology,
127 (5),
1267-1268.
Artículo
392 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Alagon,A.. Antigenic cross-reactivity between sixteen venoms from scorpions belonging to six genera.
Clinical Toxicology,
45 (2),
158-163.
Biographical-Item
393 - Alagon,A., Clement-Carretero,H., Lomonte,B., Gutierrez,J.M., Ownby,C.L.. Obituary of George V. Odell, 1926-2006.
Toxicon,
49 (6),
886-887.
Divulgación
394 - Olvera-Rodriguez,A., Alagon-Cano,A., Ramos-Cerrillo,B., Cardoso-Torres,H.M., Olvera-Rodriguez,F.. La partitura de la araña violinista: Envenenamiento fatal.
Hypatia,
22.
Editorial Material
395 - Stock,R.P., Massougbodji,A., Alagon,A., Chippaux,J.P.. Bringing antivenoms to Sub-Saharan Africa.
Nature Biotechnology,
25 (2),
173-177.
Artículo
396 - Almagro,J.C., Martinez,L., Smith,S.L., Alagon,A., Estevez,J., Paniagua,J.. Analysis of the horse V(H) repertoire and comparison with the human IGHV germline genes, and sheep, cattle and pig V(H) sequences.
Molecular Immunology,
43 (11),
1836-1845.
Artículo
397 - Olvera,A., Ramos-Cerrillo,B., Estevez,J., Clement,H., de Roodt,A., Paniagua-Solis,J., Vazquez,H., Zavaleta,A., Salas-Arruz,M., Stock,R.P., Alagon,A.. North and South American Loxosceles spiders: Development of a polyvalent antivenom with recombinant sphingomyelinases D as antigens.
Toxicon,
48 (1),
64-74.
Artículo
398 - de Roodt,A.R., Estevez-Ramirez,J., Paniagua-Solis,J.F., Litwin,S., Carvajal-Saucedo,A., Dolab,J.A., Robles-Ortiz,L.E., Alagon,A.. [Toxicity of venoms from snakes of medical importance in Mexico].
Gaceta Medica de Mexico,
141 (1),
13-21.
Artículo
399 - de Roodt,A.R., Salomon,O.D., Orduna,T.A., Robles-Ortiz,L.E., Paniagua-Solis,J.F., Cano,A.A.. Poisoning by bee sting.
Gaceta Medica de Mexico,
141 (3),
215-222.
Artículo
400 - Ramos,M.A., Sanchez-Lopez,R., Mares,R.E., Olvera,F., Alagon,A.. Identification of an Entamoeba histolytica gene encoding a protein disulfide isomerase that functionally complements the dsbA mutation in Escherichia coli.
Molecular and Biochemical Parasitology,
143 (2),
236-240.
Artículo
401 - Sadurni,P., Alagon,A., Aliev,R., Burillo,G., Hoffman,A.S.. Immobilization of streptavidin-horseradish peroxidase onto a biotinylated poly(acrylic acid) backbone that had been radiation-grafted to a PTFE film.
Journal of Biomaterials Science-Polymer Edition,
16 (2),
181-187.
Artículo
402 - Salgado,M., Villagomez-Castro,J.C., Rocha-Rodriguez,R., Sabanero-Lopez,M., Ramos,M.A., Alagon,A., Lopez-Romero,E., Sanchez-Lopez,R.. Entamoeba histolytica: Biochemical and molecular insights into the activities within microsomal fractions.
Experimental Parasitology,
110 (4),
363-373.
Artículo
403 - Sanchez,R., Saralegui,A., Olivos-Garcia,A., Scapolla,C., Damonte,G., Sanchez-Lopez,R., Alagon,A., Stock,R.P.. Entamoeba histolytica: intracellular distribution of the sec61alpha subunit of the secretory pathway and down-regulation by antisense peptide nucleic acids.
Experimental Parasitology,
109 (4),
241-251.
Artículo
404 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Mancilla-Nava,R., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics of a F(ab')(2) scorpion antivenom in healthy human volunteers.
Toxicon,
46 (7),
797-805.
News Item
405 - Chippaux,J.P., Stock,R.P., Alagon,A.. Report of the 2nd international conference on envenomations in Africa (Deuxieme colloque international sur les envenomations en Afrique).
Toxicon,
46 (1),
115-118.
Artículo
406 - de Roodt,A.R., Paniagua-Solis,J.F., Dolab,J.A., Estevez-Ramirez,J., Ramos-Cerrillo,B., Litwin,S., Dokmetjian,J.C., Alagon,A.. Effectiveness of two common antivenoms for North, Central, and South American Micrurus envenomations.
Journal of Toxicology - Clinical Toxicology,
42 (2),
171-178.
Artículo
407 - Ramos-Cerrillo,B., Olvera,A., Odell,G.V., Zamudio,F., Paniagua-Solis,J., Alagon,A., Stock,R.P.. Genetic and enzymatic characterization of sphingomyelinase D isoforms from the North American fiddleback spiders Loxosceles boneti and Loxosceles reclusa.
Toxicon,
44 (5),
507-514 .
Divulgación
408 - Alagon,A., Odell,G.. Acroceroide parasitism of the Mexican tarantula Aphonopelma duplex.
Forum Magazine.American Tarantula Society,
13,
57-58.
Divulgación
Artículo
410 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Aguilar,V., Alagon,A.. Relationship between plasmatic levels of various cytokines, tumour necrosis factor, enzymes, glucose and venom concentration following Tityus scorpion sting.
Toxicon,
41 (3),
367-375.
Nacional
411 - Alagon,A., Possani,L.D.. Desarrollo de nuevos f rmacos a partir de la fauna tropical. Fronteras de la Biología en los Inicios del Siglo XXI, Módulo VII .
123-160,
Mexico,D.F..
Nacional
412 - Alagon,A., Carillo,C., Chavez-Haro,A., De la Mora-Zerpa,C., Larralde,C., Lamas,N, Martin,E, Osnaya-Romero,N., Perez,Y, Possani,L.D., Romero-Zamora,L.. Práctica Médica Efectiva- Alacranismo (T63.2, X22).
Mexico.
Artículo
413 - Nieto-Sotelo,J., Martinez,L.M., Ponce,G., Cassab,G.I., Alagon,A., Meeley,R.B., Ribaut,J.M., Yang,R.. Maize HSP101 Plays Important Roles in Both Induced and Basal Thermotolerance and Primary Root Growth.
Plant Cell,
14 (7),
1621-1633.
Artículo
414 - Ramos,M.A., Sanchez-Lopez,R., Olvera,F., Alagon,A.. Entamoeba histolytica genomic organization: identification, structure, and phylogenetic relationship of two serine-threonine protein kinases.
Experimental Parasitology,
100 (2),
135-139.
Artículo
415 - Sanchez,R., Alagon,A., Stock,R.P.. Entamoeba histolytica: intracellular distribution of the proteasome.
Experimental Parasitology,
102 (3-4),
187-190.
Divulgación
416 - Alagon,A.. Anticuerpos seguros y eficaces: la revoluacion de los nuevos antivenenos.
Revista Universidad de Mexico,
617.
Divulgación
Artículo
418 - Juarez,P., Sanchez-Lopez,R., Stock,R.P., Olvera,A., Ramos,M.A., Alagon,A.. Characterization of the Ehrab8 gene, a marker of the late stages of the secretory pathway of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
116 (2),
223-228.
Artículo
419 - Stock,R.P., Olvera,A., Sanchez,R., Saralegui,A., Scarfi,S., Sanchez-Lopez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Alagon,A.. Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers.
Nature Biotechnology,
19 (3),
231-234.
Divulgación
420 - Ramos,M.A., Alagon,A.. Ruta secretoria y Entamoeba histolytica.
Mensaje Bioquimico,
25,
111-128.
Artículo
421 - Gutierrez,A., Sanchez-Lopez,R., Ramos,M.A., Alagon,A.. Cloning of the Entamoeba histolytica STT3 gene, a subunit of the oligosaccharyltransferase complex.
Archives of Medical Research,
31 (4 Suppl),
S162-S164.
Artículo
422 - Juarez,P., Sanchez-Lopez,R., Ramos,M.A., Stock,R.P., Alagon,A.. Rab8 as a molecular model of vesicular trafficking to investigate the latter steps of the secretory pathway in Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S157-S159.
Artículo
423 - Ramos,M.A., Alagon,A.. Molecular cloning of a gene encoding a PDI-like protein from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S173-S175.
Artículo
424 - Ramos,M.A., Sanchez-Lopez,R., Alagon,A.. Genomic organization of a 7 Kb gene cluster from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S263-S265.
Artículo
425 - Sanchez-Lopez,R., Gutierrez,A., Juarez,P., Olvera,A., Olvera,F., Ramos,M.A., Sanchez,R., Saralegui,A., Stock,R.P., Alagon,A.. Molecular genetics of the secretory pathway in Entamoeba histolytica: an overview.
Archives of Medical Research,
31 (4 Suppl),
S151-S152.
Artículo
426 - Sanchez-Lopez,R., Siminovich,B., Alagon,A.. Entamoeba histolytica codes for a protein homologue of the Sec61 alpha subunit, a component of the endoplasmic reticulum translocon.
Archives of Medical Research,
31 (4 Suppl),
S168-S170.
Artículo
427 - Stock,R.P., Olvera,A., Scarfi,S., Sanchez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Landt,O., Alagon,A.. Inhibition of neomycin phosphorotransferase expression in Entamoeba histolytica with antisense peptide nucleic acid (PNA) oligomers.
Archives of Medical Research,
31 (4 Suppl),
S271-S272.
Nacional
428 - Estrada-Galvan,B., Scheinvar,L., Alagon,A., Olalde-Parra,G.. Resultados preliminares de electroforesis en proteínas como método auxiliar en la taxonomía de Opuntia spp.
Acta Cientifica Potosina,
15 (1),
7-24.
Artículo
429 - Que,X., Kim,D., Alagon,A., Hirata,K., Shike,H., Shimizu,C., Gonzalez,A., Burns,J.C., Reed,S.L.. Pantropic retroviral vectors mediate gene transfer and expression in Entamoeba histolytica.
Molecular and Biochemical Parasitology,
99 (2),
237-245.
Artículo
430 - Sanchez-Gonzalez,M., Alagon,A., Rodriguez-Sotres,R., Lopez-Munguia,A.. Proteolytic processing of dextransucrase of Leuconostoc mesenteroides.
Fems Microbiology Letters,
181 (1),
25-30.
Artículo
431 - Sanchez-Lopez,R., Gama-Castro,S., Ramos,M.A., Merino,E., Lizardi,P.M., Alagon,A.. Cloning and expression of the Entamoeba histolytica ERD2 gene.
Molecular and Biochemical Parasitology,
92 (2),
355-359.
Artículo
432 - Vargas-Villarreal,J., Olvera-Rodriguez,A., Mata-Cardenas,B.D., Martinez-Rodriguez,H.G., Said-Fernandez,S., Alagon-Cano,A.. Isolation of an Entamoeba histolytica intracellular alkaline phospholipase A(2).
Parasitology Research,
84 (4),
310-314.
Nacional
433 - Estrada,G., Sanchez,R., Lizardi,P.M., Alagon,A.. Entamoeba histolytica y la reaccion en cadena de polimerasa por hibridazion y liberacion enzimatica (PCR-HERA). Biologia molecular en medicina.
Coleccion de textos politecnicos, series biotecnologicas.,
47-60,
Mexico DF.
Artículo; Actas Paper
434 - Olvera,A., Olvera,F., Vines,R.R., Recillas-Targa,F., Lizardi,P.M., Dhar,S., Bhattacharya,S., Petri,W.,Jr, Alagon,A.. Stable transfection of Entamoeba histolytica trophozoites by lipofection.
Archives of Medical Research,
28 . (Spec No:49-51),
49-51.
Artículo
435 - Ramos,M.A., Mercado,G.C., Salgado,L.M., Sanchez-Lopez,R., Stock,R.P., Lizardi,P.M., Alagon,A.. Entamoeba histolytica contains a gene encoding a homologue to the 54 kDa subunit of the signal recognition particle.
Molecular and Biochemical Parasitology,
88 (1-2),
225-235.
Artículo; Actas Paper
436 - Ramos,M.A., Stock,R.P., Lizardi,P.M., Alagon,A.. The secretory pathway of Entamoeba histolytica: characterization and expression of the SRP54 gene.
Archives of Medical Research,
28 (Spec No:56-8.),
56-58.
Artículo
437 - Ramos,M.A., Stock,R.P., Sanchez-Lopez,R., Olvera,F., Lizardi,P.M., Alagon,A.. The Entamoeba histolytica proteasome alpha-subunit gene.
Molecular and Biochemical Parasitology,
84 (1),
131-135.
Artículo; Actas Paper
438 - Sanchez-Lopez,R., Gama-Castro,S., Lizardi,P.M., Alagon,A.. The secretory pathway of Entamoeba histolytica: characterization and expression of the ERD2 gene.
Archives of Medical Research,
28 (Spec No:59-61.),
59-61.
Artículo
439 - Estrada,G., Colin,L., Gaytan,P., Alagon,A., Lizardi,P.M.. Sequence-specific detection of PCR-amplified DNA by restriction enzyme release of hybrids.
Molecular and cellular probes,
10 (3),
179-185.
Artículo
440 - Miranda,R., Salgado,L.M., Sanchez-Lopez,R., Alagon,A., Lizardi,P.M.. Identification and analysis of the u6 small nuclear RNA gene from Entamoeba histolytica.
Gene,
180 (1-2),
37-42.
Artículo
441 - Ortega-Pierres,G., Alagon,A., Cortes,A., Olvera,F., Olvera,A., Gonzalez,A., Lizardi,P., Berzunza-Cruz,M., Saavedra-Lira,E., Perez-Montfort,R., Velasco-Castrejon,O., Sotero-Delgado Dominguez,I., Becker,I., Hernandez,R., Martinez-Calvillo,S., Frixione,E., Ruiz,L., Santillan,M., Vega,L., Tejero,J.M., Undeen,A.H., Kretschmer,R.R., Herion,P., Saavedra,R., Yepez-Mulia,L.. [Impact of new methodologies in the study of parasites].
Gaceta Medica de Mexico,
132 (5),
475-517.
Nacional
Artículo
443 - Michel,B., Lizardi,P.M., Alagon,A., Zurita,M.. Identification and analysis of the start site of ribosomal RNA transcription of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
73 (1-2),
19-30.
Artículo
444 - Noeske-Jungblut,C., Haendler,B., Donner,P., Alagon,A., Possani,L., Schleuning,W.D.. Triabin, a highly potent exosite inhibitor of thrombin.
Journal of Biological Chemistry,
270 (48),
28629-28634.
Internacional
445 - Dehesa-Davila,M., Alagon,A.C., Possani,L.D.. Clinical toxicology of scorpion stings. Handbook of clinical toxicology of animal venoms and poisons.
221-238,
New York.
Artículo
446 - Noeske-Jungblut,C., Kratzschmar,J., Haendler,B., Alagon,A., Possani,L., Verhallen,P., Donner,P., Schleuning,W.D.. An inhibitor of collagen-induced platelet aggregation from the saliva of Triatoma pallidipennis.
Journal of Biological Chemistry,
269 (7),
5050-5053.
Artículo
447 - Palmeros,B., Guereca,L., Alagon,A., Soberon-Chavez,G.. Biochemical characterization of the lipolytic activity of pseudomonas aeruginosa IGB 83.
Process Biochemistry,
29 (3),
207-212.
Artículo
448 - Cevallos,M.A., Porta,H., Alagon,A.C., Lizardi,P.M.. Sequence of the 5.8S ribosomal gene of pathogenic and non-pathogenic isolates of Entamoeba histolytica.
Nucleic Acids Research,
21 (2),
355-355.
Note
449 - Cevallos,M.A., Navarro-Duque,C., Varela-Julia,M., Alagon,A.C.. Molecular mass determination and assay of venom hyaluronidases by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Toxicon,
30 (8),
925-930.
Note
450 - Michel,B., Alagon,A., Lizardi,P.M., Zurita,M.. Characterization of a repetitive DNA element from Entamoeba histolytica.
Molecular and Biochemical Parasitology,
51 (1),
165-168.
Artículo
451 - Possani,L.D., Fletcher,P.L., Fletcher,M.D., Rode,G.S., Mochca-Morales,J., Lucas,S., Coronas,F.V., Alagon,A.C., Martin,B.M.. Structural and functional characteristics of toxins purified from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello.
Memorias do Instituto Butantan,
54 (2),
35-52.
Artículo
452 - Schleuning,W.D., Alagon,A., Boidol,W., Bringmann,P., Petri,T., Kratzschmar,J., Haendler,B., Langer,G., Baldus,B., Witt,W.. Plasminogen activators from the saliva of Desmodus rotundus (common vampire bat): unique fibrin specificity.
Annals of the New York Academy of Sciences,
667,
395-403.
*
Artículo
453 - Kratzschmar,J., Haendler,B., Langer,G., Boidol,W., Bringmann,P., Alagon,A., Donner,P., Schleuning,W.D.. The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression.
Gene,
105 (2),
229-237.
Note
454 - Vargas-Villarreal,J., Martin-Polo,J.J., Reynaud,E., Alagon,A.C.. A new affinity adsorbent for the purification of phospholipases A1 and A2 from animal venoms.
Toxicon,
29 (1),
119-124.
Artículo
455 - Zurita,M., Alagon,A., Vargas-Villarreal,J., Lizardi,P.M.. The Entamoeba histolytica rDNA episome: nuclear localization, DNAase I sensitivity map, and specific DNA-protein interactions.
Molecular Microbiology,
5 (8),
1843-1851.
Note
456 - Laclette,J.P., Alagon,A., Willms,K., Torre-Blanco,A.. Purification of antigen B from Taenia solium cysticerci by affinity to mammalian collagen.
Journal of Parasitology,
76 (2),
273-275.
Artículo
457 - Alagon,A.C., Guzman,H.S., Martin,B.M., Ramirez,A.N., Carbone,E., Possani,L.D.. Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch.
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology,
89 (1),
153-161.
458 - Alagon Cano, Alejandro. Enzimas hidroliticas del veneno de heloderma horridum horridum : fosfolipasa A2 y calicreina .
Doctorado en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
Artículo
459 - Alagon,A., Possani,L.D., Smart,J., Schleuning,W.D.. Helodermatine, a kallikrein-like, hypotensive enzyme from the venom of Heloderma horridum horridum (Mexican beaded lizard).
Journal of Experimental Medicine,
164 (6),
1835-1845.
Artículo
460 - Sosa,B.P., Alagon,A.C., Martin,B.M., Possani,L.D.. Biochemical characterization of the phospholipase A2 purified from the venom of the Mexican beaded lizard (Heloderma horridum horridum Wiegmann).
Biochemistry,
25 (10),
2927-2933.
*
Artículo
461 - King,T.P., Alagon,A.C., Kuan,J., Sobotka,A.K., Lichtenstein,L.M.. Immunochemical studies of yellowjacket venom proteins.
Molecular Immunology,
20 (3),
297-308.
*
Artículo
462 - Alagon,A.C., Maldonado,M.E., Julia,J.Z., Sanchez,C.R., Possani,L.D.. Venom from two sub-species of Heloderma horridum (Mexican beaded lizard): general characterization and purification of N-benzoyl-L-arginine ethyl ester hydrolase.
Toxicon,
20 (2),
463-475.
*
Artículo
463 - King,T.P., Alagon,A., Kochoumian,L., Kuan,J., Sobotka,A., Lichtenstein,L.M.. Limited proteolysis of antigens E and K from ragweed pollen.
Archives of Biochemistry and Biophysics,
212 (1),
127-135.
*
Artículo
464 - Possani,L., Steinmetz,W.E., Dent,M.A., Alagon,A.C., Wuthrich,K.. Preliminary spectroscopic characterization of six toxins from Latin American scorpions.
Biochimica et Biophysica Acta (BBA) - Protein Structure,
669 (2),
183-192.
*
Artículo
465 - Alagon,A.C., King,T.P.. Activation of polysaccharides with 2-iminothiolane and its uses.
Biochemistry,
19 (18),
4341-4345.
*
Artículo
466 - Alagon,A.C., Molinar,R.R., Possani,L.D., Fletcher,P.L., Cronan,J.E., Julia,J.Z.. Venom from the snake Bothrops asper Garman. Purification and characterization of three phospholipases A2.
Biochemical Journal,
185 (3),
695-704.
*
Artículo
467 - Possani,L.D., Fletcher,P.L., Alagon,A.B., Alagon,A.C., Julia,J.Z.. Purification and characterization of a mammalian toxin from venom of the Mexican scorpion, Centruroides limpidus tecomanus Hoffmann.
Toxicon,
18 (2),
175-183.
*
Note
468 - Possani,L.D., Sosa,B.P., Alagon,A.C., Burchfield,P.M.. The venom from the snakes Agkistrodon bilineatus Taylori and Crotalus durissus Totonacus: lethality, biochemical and immunological properties.
Toxicon,
18 (3),
356-360.
*
469 - Alagon Cano, Alejandro. Estudio sobre los venenos de varias especies zoologicas.
Instituto de Investigacions Biomedicas,
Maestria en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
Artículo
470 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Varela,M.J., Julia,J.Z.. Purification and characterization of a phospholipase A2 from the venom of the coral snake, Micrurus fulvius microgalbineus (Brown and Smith).
Biochemical Journal,
179 (3),
603-606.
*
Artículo
471 - Sosa,B.P., Alagon,A.C., Possani,L.D., Julia,J.Z.. Comparison of phospholipase activity with direct and indirect lytic effects of animal venoms upon human red cells.
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry,
64 (2),
231-234.
*
Nacional
472 - Arauco,R., Alagon,A.. [Propanolol in arterial hypertension. Beta-blockaders. Recent advances].
Prensa médica mexicana,
44 (5-6),
97-104.
*
Artículo
473 - King,T.P., Sobotka,A.K., Alagon,A., Kochoumian,L., Lichtenstein,L.M.. Protein allergens of white-faced hornet, yellow hornet, and yellow jacket venoms.
Biochemistry,
17 (24),
5165-5174.
*
Artículo
474 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Erickson,B.W.. Purification and properties of mammalian toxins from the venom of Brazilian Scorpion Tityus serrulatus Lutz and Mello.
Archives of Biochemistry and Biophysics,
180 (2),
394-403.
*
Artículo
475 - Frenk,J., Acuna,D.L., Bobadilla,J.L., Alagon,A.. [Liberal medicine and institutional medicine in Mexico].
Salud Publica de Mexico,
18 (3),
481-493.
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- Teléfonos
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