Dr. Alejandro Alagón Cano
Investigador Emérito
Alejandro Alagón Cano (Ciudad de México, 1954) es un médico, investigador, catedrático y académico mexicano. Se ha especializado en las áreas de biotecnología de los anticuerpos y toxinología (véase toxina), en la investigación para el mejoramiento de antivenenos y el desarrollo de nuevos antivenenos. Recibió el Premio Nacional de Ciencias y Artes en el 2005.
Biología Molecular y Bioquímica de venenos de animales ponzoñosos
Bioprocesos con aplicaciones biotecnológicas y para la generación de medicamentos biotecnológicos
Antivenenos para animales ponzoñosos con una pureza y refinamiento que reducen de forma importante las reacciones adversas típicas de estas terapias de emergencia.
Número de registros: 24
- Activos
- Vencidos
- Desarrollo de un antiveneno recombinante a partir de anticuerpos monoclonales para tratar pacientes envenenados por araña viuda negra (latrodectus sp.), DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2025 - 2027
- Consecuencias funcionales de la variación genómica, transcriptómica y proteómica en el veneno de las serpientes de cascabel de cola negra y sus implicaciones en el tratamiento con antiveneno, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2020 - 2024
- Venenos y antivenenos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2020 - 2025
- Desarrollo de un sistema para evaluar la respuesta inmune temprana y convaleciente de pacientes infectados con sars-cov-2 y de inmunoterápicos para enfermos en estado crítico por covid-19, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1900
- Caracterización del veneno de tres serpientes de importancia médica en méxico: investigación básica y mejoramiento de antivenenos., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2021 - 2023
- 2º curso de animales venenosos en méxico, biología, investigación y clínica, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2018
- Investigación de venenos de serpientes para el mejoramiento de antivenenos, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2018 - 2021
- Automatización de llenado de bolsas de agua para ratas y ratones del bioterio del instituto de biotecnología-unam, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2015 - 2016
- Caracterización funcional del veneno de agkistrodon, así como la respuesta inmune en caballos contra los mismos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2014 - 2018
- Biotecnología de anticuerpos terapéuticos y diagnósticos, y toxinología aplicada, PRESUPUESTO UNAM, 2014 - 2020
- Identificación, análisis molecular y expresión heteróloga de neurotoxinas provenientes de elápidos y vipéridos para la generación de antivenenos de alta calidad, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2014 - 2017
- Análisis molecular y expresión heteróloga de neurotoxinas provenientes del veneno de coral (elápidos) para la generación de antivenenos de alta calidad, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2011 - 2013
- Phase 2 clinical trial of coralmyn for coral snake bite, UNIVERSITY OF ARIZONA, 2010 - 2016
- Desarrollo de un antiveneno de cobertura europea para el tratamiento de la intoxicación por mordedura de serpiente, FONDO DE COOPERACIÓN INTERNACIONAL EN CIENCIA Y TECNOLOGÍA UNIÓN EUROPEA - MÉXICO, 2009 - 2012
- Reconocimiento cruzado de venenos de coralillos de norteamerica, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2009
- Proyecto piloto referente al estudio del sistema linfático; a llevarse a cabo durante la segunda reunión de grupo de investigación sobre linfotoxicología, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2008 - 2009
- Toxoides recombinantes de arañas latrodectus y loxosceles., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2005
- Inhibición de funciones celulares en células humanas y de entamoeba histolytica mediante pna antisentido y antigene convalentemente modificados y usando glóbulos rojos acarreadores., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2002 - 2004
- Anticuerpos recombinantes humanos: obtención y evaluación funcional para el desarrollo de antivenenos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2000 - 2002
- Repertorios inteligentes de anticuerpos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2000 - 2002
- Caracterización de venenos y toxinas selectos de arañas mexicanas, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1999 - 2001
- Inhibición de funciones celulares en células humanas y en entamoeba histolytica mediante ácidos péptido nucleicos (pna) antisense y antigene., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1999 - 2002
- Enfoques moleculares para el estudio de la vía secretoria en entamoeba histolytica (3a. etapa), DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1997 - 2000
- Diseño de moléculas mejoradas de pna (ácido péptido-nucléico) para la expresión de genes específicos, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1996 - 1998
Nivel D del PRIDE
Nivel Investigador Emérito del SNII
Nivel Investigador Emérito del SNII
Doctorado, en Ciencias, Instituto de Investigaciones Biomedicas, UNAM (1983)
Maestría, en Ciencias, Instituto de Investigaciones Biomedicas, UNAM (1980)
Licenciatura, Medico Cirujano, Fac. de Medicina, UNAM (1978)
Premio Luis Elizondo al sentido humano 2013, Sistema Tecnológico de Monterrey, 2013
Premio Nacional de Ciencias y Artes, Gobierno de la República, 2005
Premio UNAM 2004 Innovación Tecnológica, 2004
- Activos
- Graduados
-
Doctorado (UNAM u Otros)
-
Generación de antiveneno experimental neutralizante del veneno de abeja (Apis mellifera) y la reacción anafiláctica
-
Maestría (UNAM u Otros)
-
Audrey Michelle Rodríguez Solís
Cuantificación de veneno, familias proteicas y antiveneno en muestra de sangre de pacientes mordidos por vipéridos y elápidos mexicanos.
1 - Sanchez Ramirez,Fatima (2026). Producción de anticuerpos recombinantes a partir de anticuerpos monoclonales neutralizantes del veneno de Latrodectus mactans (Walckenaer, 1805).
Instituto de Biotecnologia,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Alagon Cano,Alejandro
2 - Guadarrama Martinez, Alid (2025). Caracterizacion bioquimica y proteomica del veneno de crotalus atrox.
Instituto de Biotecnología,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
3 - Yanez Mendoza, Manuel Francisco (2024). Caracterizacion funcional del veneno de la serpiente de coral mexicana Micrurus diastema.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
4 - Losoya Uribe, Luis Fernando (2024). Obtencion de un anticuerpo monoclonal neutralizante de la actividad esfingomielinasa D de Loxosceles boneti (Gertsch, 1958), como candidato en el desarrollo de un anticuerpo recombinante quimerico.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
5 - Corkidi Zajur, Tania (2023). Caracterizacion de la sphenotoxina de Ophryacus sphenophrys y su comparacion con la crotoxina clasica.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
6 - Aguayo Avalos, Oscar (2023). Evolucion de titulos de anticuerpos y potencias neutralizantes de sueros de caballo hiperinmunizados con mezclas complejas de venenos de viperidos y elapidos.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
7 - Neri Castro, Edgar Enrique (2021). Farmacocinética en sangre y en linfa del veneno de la cascabel neotropical (Crotalus simus) en un modelo ovino.
Instituto de Investigaciones Biomedicas,
Doctorado en Ciencias Biomedicas,
UNAM.
*
Asesor: Alagon Cano, Alejandro
8 - Colis Torres, Andrea (2021). Caracterizacion intraespecifica del veneno de Crotalus basiliscus (Cope, 1864) y su neutralizacion con un antiveneno mexicano.
Instituto de Biotecnología,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Alagon Cano, Alejandro
9 - Sarmiento Acuña, Karen Solanyi (2020). Comparación de la especificidad y capacidad neutralizante de dos antivenenos antiofídicos retados con veneno de serpiente del género Bothrops de Colombia.
Facultad de Medicina,
Maestría en Toxicología,
Universidad Nacional de Colombia.
*
Asesor: Castiblanco Rodríguez, Ana Lucía, Alagón Cano, Alejandro
10 - Corkidi Zajur, Tania (2020). Biodistribución de fragmentos de inmunoglobulinas tipo F(ab)? 2 en ratones, por análisis de imágenes.
Instituto de Investigacion en Ciencias Basicas y Aplicadas,
Licenciatura en Ciencias,
UAEM.
*
Asesor: Alagon Cano, Alejandro
11 - Ponce Lopez, Jose Roberto (2020). Expresion heterologa de crotamina de Crotalus molossus nigrescens fusionada a esfingomielinasa D de loxosceles en Escherichia coli, para su utilizacion como posible inmunogeno.
Instituto de Biotecnologia,
Maestría en Ciencias Bioquímicas,
UNAM.
Asesor: Alagon Cano, Alejandro
12 - Benard Valle, Melisa (2020). Caracterizacion funcional y analisis de especificidad del veneno de la serpiente de coral Micrurus browni browni.
Instituto de Biotecnologia,
Doctorado en Bioquímicas,
UNAM.
Asesor: Alagon Cano, Alejandro
13 - Borja Jiménez, Juan Miguel (2019). Variabilidad genética y caracterización bioquímica de las
metaloproteinasas y la toxina mojave de Crotalus scutulatus y Crotalus molossus del desierto
Chihuahuense.
Facultad de Ciencias Químicas,
Doctorado en Ciencias Biomédicas,
Universidad Juárez del Estado de Durango.
*
Asesor: Pérez Morales,Rebeca, Alagón Cano, Alejandro
14 - Castillo Perez, Irene Maria (2019). Producción de conjugados de crotamina y su evaluación como inmunógenos.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
*
Asesor: Alagon Cano, Alejandro
15 - Barcenas Arriaga, Sergio (2018). Caracterizacion bioquimica y biologica del veneno de Bothrops asper (Garman, 1884) de Mexico.
Facultad de Ciencias,
Maestria en Ciencias Biologicas,
UNAM.
*
Asesor: Alagon Cano, Alejandro
16 - Roman Dominguez, Luis (2018). Aislamiento y caracterización de componentes con actividad edematizante presentes en el veneno de la serpiente Agkistrodon bilineatus.
Facultad de Medicina,
Maestria en Medicina Molecular,
UAEM.
*
Asesor: Petricevich, Vera Lucia, Alagon Cano, Alejandro
17 - Dzib Hau, Maria Fernanda (2016). Caracterizacion de los principales compuestos presentes en secreciones obtenidas de las glandulas parotidas de rhinella marina.
Instituto de Biotecnologia,
76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
18 - Hernandez Davila, Isabel Arely (2015). Crotoxina en el veneno de la serpiente de cascabel crotalus simus en Mexico : su relacion con la toxicidad y distribucion geografica.
Instituto de Biotecnologia,
76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
19 - Vergara Bahena, Irene (2015). Caracterizacion del veneno de micrurus fulvius y biodistribucion in vivo de su principal toxina radiomarcada con 67galio.
Instituto de Biotecnologia,
94 paginas,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
20 - Paniagua Meza, Dayanira (2014). Participacion del sistema linfatico en la absorcion y distribucion del veneno de micrurus fulvius.
Instituto de Biotecnologia,
74 paginas,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
21 - Mendoza Vera, Miguel Angel (2014). Expresion, purificacion y caracterizacion de la esfingomielinasa D recombinante de rhipicephalus microplus.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
22 - Guerrero Garzon, Jaime Felipe (2014). Clonacion, expresion y caracterizacion de alfaneurotoxinas de serpientes de coral mexicanas.
Instituto de Biotecnologia,
83 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
23 - Carbajal Saucedo, Alejandro (2014). Caracterizacion biologica, bioquimica e inmunoquimica del veneno de Micrurus laticollaris : bases para el desarrollo de un antiveneno de amplio espectro contra coralillos.
Instituto de Biotecnologia,
90 paginas,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
24 - Barron Castillo, Ulises (2014). Expresion de la alfaneurotoxina mlata1 de micrurus laticollaris en pichia pastoris y evaluacion de su uso como inmunogeno.
Instituto de Biotecnologia,
76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
25 - Calderon Corona, Arlene (2011). Caracterizacion de la respuesta inmune humoral en caballos contra el veneno de Micrurus tener.
Instituto de Biotecnologia,
78 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
26 - Benard Valle, Melisa (2011). Caracterizacion bioquimica del veneno de la serpiente de coral Micrurus tener.
Instituto de Biotecnologia,
42 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
27 - Chavez Mendez, Ariana (2011). Participacion de los productos fosfoceramida y lisofosfatidato generados por la esfingomielinasa D del veneno de arana loxosceles, en la toxicidad de la enzima.
Instituto de Biotecnologia,
vi, 76 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
28 - Rosa Hernandez, Guillermo de la (2011). Produccion de toxoides de serpientes africanas mediante radiacion gamma.
Instituto de Biotecnologia,
93 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
29 - Vergara Bahena, Irene (2010). Influencia de la via de administracion en la capacidad neutralizante in vivo de dos antivenenos.
Instituto de Biotecnologia,
xi, 73 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
30 - Jimenez Martinez, Lucia (2009). Neutralizacion de esfingomielinasa D recombuinante de Loxosceles boneti con varias preparaciones derivadas de suero hiperinmune de caballo.
FMVZ,
Medico Veterinario Zootecnista,
UNAM.
*
Asesor: Alagon Cano, Alejandro
31 - Moctezuma Gonzalez, Claudia Lizbeth (2008). Produccion de un fragmento de anticuerpo recombinante quimerico anti esfingomielinasa D contra la mordedura de la arana Loxosceles.
Instituto de Biotecnologia,
53 paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
32 - Chavez Mendez, Ariana (2007). Desarrollo, optimizacion y validacion de un metodo analitico tipo ELISA para cuantificar veneno de escorpion Centruroides en plasma humano.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
Asesor: Alagon Cano, Alejandro
33 - Olguin Perez, Laura Patricia (2006). Caracterizacion de la actividad enzimatica de la esfingomielinasa D del veneno de las aranas violinistas Loxosceles boneti, L. reclusa Y L. laeta.
Instituto de Biotecnologia,
41, [2] paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
34 - Ramos Cerrillo, Blanca Margarita (2005). Produccion, evaluacion y caracterizacion de los inmunogenos recombinantes de las esfingomielinasa de L. boneti, L. reclusa y L. laeta.
Instituto de Biotecnologia,
(97, [15] paginas,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
35 - Prud'Homme Sanchez, Monica Adriana (2004). Produccion y evaluacion de antigenos recombinantes de la alatrotoxina de Latrodectus mactans.
Instituto de Biotecnologia,
(vii, 77 paginas,
Maestria en Ciencias (Bioquimica),
UNAM.
Asesor: Alagon Cano, Alejandro
36 - Carbajal Saucedo, Alejandro (2004). Comparacion inmunoquimica del veneno de serpientes de coral (Elapidae : Mirurus, Micruroides) mexicanas.
Instituto de Biotecnologia,
53 paginas,
Maestria en Ciencias (Bioquimica),
UNAM.
Asesor: Alagon Cano, Alejandro
37 - Fuentes Silva, Deyanira (2003). Plegamiento in vitro de una toxina sintetica de arana.
Instituto de Biotecnologia,
76, VI paginas,
Maestria en Ciencias Quimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
38 - Ramos Cerrillo, Blanca Margarita (2002). Comparacion bioquimica, inmunologica y toxinologica de los venenos de Loxosceles boneti y Loxosceles reclusa.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
Asesor: Alagon Cano, Alejandro
39 - Ramos Ibarra, Marco Antonio (2001). Clonacion y localizacion intracelular de la subunidad de 54 kDa de la particula de reconocimiento de la secuencia senal (SRP54) de Entamoeba histolytica.
Instituto de Biotecnologia,
74, VII paginas,
Doctor en Ciencias Bioquimicas,
UNAM.
Asesor: Alagon Cano, Alejandro
40 - Ortiz Suri, Ernesto (1998). Moleculas de PNA en sistemas fluorescentes de deteccion por hibridacion en la discriminacion de alelos.
Instituto de Biotecnologia,
56, [10] paginas,
Doctorado en Biotecnologia,
UNAM.
41 - Gonzalez Juarez, Carlos Antonio (1996). Desarrollo de una prueba diagnostica para la deteccion de hipotiroidismo congenito empleando anticuerpos monoclonales.
Instituto de Biotecnologia,
87, VI paginas,
Maestria en Biotecnologia,
UNAM.
Asesor: Alagon Cano, Alejandro
42 - Hernandez Vargas, Rene (1995). Caracterizacion molecular de un fragmento de un gene similar a HSP70 de Entamoeba histolytica.
Instituto de Biotecnologia,
57 paginas,
Maestria en Biotecnologia,
UNAM.
43 - Mercado Besserer, Gabriel Cuauhtemoc (1994). Obtencion y caracterizacion de un fragmento del gene SRP54 de Entamoeba histolytica.
Instituto de Biotecnologia,
Licenciatura en Investigacion Biomedica Basica,
UNAM.
44 - Herrera Medina, Enrique Macario (1992). Caracterizacion bioquimica del veneno de la hormiga Pogonomyrmex rugosus con enfasis en la fosfolipasa A1.
Instituto de Biotecnologia,
53 paginas,
Maestria en Biotecnologia,
UNAM.
Asesor: Alagon Cano, Alejandro
45 - Cuevas Aguirre, Delia Anatolia (1992). Caracterizacion bioquimica de saliva de triatominos mexicanos.
Maestria en Biotecnologia,
UNAM.
46 - Astorga Chaidez, Eleuterio (1991). Actividad inhibitoria de la agregacion plaquetaria por la saliva del murcielago hematofogo.
Instituto de Biotecnologia,
Maestría en Biotecnología,
UNAM.
Asesor: Alagon Cano, Alejandro
47 - Vargas Villarreal, Javier (1991). Aislamiento y caracterizacion de una fosfolipasa A2 de Entamoeba histolytica con actividad litica directa.
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
64 paginas,
Doctorado en Investigacion Biomedica Basica,
UNAM.
Asesor: Alagon Cano, Alejandro
48 - Sosa Pineda, Beatriz (1988). Helodermatidina, una proteasa del veneno del monstruo de cuentas (heloderma horridum horridum) que activa plasminogeno.
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
42 paginas,
Maestria en Investigacion Biomedica Basica,
UNAM.
Asesor: Alagon Cano, Alejandro
49 - Amezcua Lopez, Jose (1987). Caracterizacion bioquimica del veneno de avispas Polistesdoxsalis (Fabricius) y Polivia occidentalis nigritella du Bysson.
Facultad de Ciencias,
Licenciatura en biología,
UNAM.
*
Asesor: Alagon Cano, Alejandro
* Indica publicación con otra institución de adscripción
Total de publicaciones: 224
- Tipo
- Fecha
Artículo
50 - Antonio-Perez,A., Clement,H., Sanchez-Lopez,R., Alagon,A., Benitez-Cardoza,C.G., Ortega-Lopez,J. (2026). Chaperone-assisted chromatography oxidative refolding of disulfide-rich hyaluronidase from inclusion bodies.
Biotechnology and Bioprocess Engineering,
31,
783-795.
Revisión
51 - Benard-Valle,M., Ahmadi,S., Modahl,Cassandra M., Neri-Castro,E., Alagon,A., Boyer,L., Ljungars,A., Laustsen,A.H. (2026). Large animal models for the assessment of snakebite envenoming therapies.
npj Drug Discovery,
3 (1),
12.
Artículo
52 - Cavalcante,J.S., Almeida,J.S., Coutinho,J.V.C., Neri-Castro,E., Pucca,M.B., Alagon,A., Ferreira Junior,R.S. (2026). Translational medicine protocol for proteomics clinical research on snakebite envenoming: contributions for develop studies in mechanisms and new biomarkers.
Archives of Toxicology,
100 (4),
1617-1628.
Artículo
53 - Gonzalez-Ruiz,J.M., Huerta-Olvera,S.G., Plascencia-Jimenez,J.A., Martinez-Gallegos,E.Y., Guzman-Villalpando,J.M., Avina-Galindo,F.I., Ojeda-Vazquez,C.A., Hernandez-Munoz,E.A., Zavala-Sanchez,E.V., Vazquez-Lopez,H., Alagon,A., Banos-Hernandez,C.J. (2026). Factors associated with clinical severity in scorpion envenomation: a retrospective cross-sectional study in western Mexico between 2021 and 2025.
Frontiers in Toxicolology,
8,
1880720.
Artículo
54 - Zarzosa,V., Vazquez-Garcia,E., Lomonte,B., Rodriguez,B., Fernandez,J., Garcia-Vazquez,U.O., Zamudio,F., Olvera-Rodriguez,A., Olvera-Rodriguez,F., Hernandez-Orihuela,L., Benard-Valle,M., Alagon,A., Neri-Castro,E. (2026). Integrative venomics of the coral snake Micrurus elegans: composition, toxicity, and neutralization by antivenom.
Biochimie,
247 (agosto),
151-166.
Artículo
55 - Ahmadi,S., Burlet,N.J., Benard-Valle,M., Guadarrama-Martinez,A., Kerwin,S., Cardoso,I.A., Marriott,A.E., Edge,R.J., Crittenden,E., Neri-Castro,E., Fernandez-Quintero,M.L., Nguyen,G.T.T., O'Brien,C., Wouters,Y., Kalogeropoulos,K., Thumtecho,S., Ebersole,T.W., Dahl,C.H., Glegg-Sorensen,E.U., Jansen,T., Boddum,K., Manousaki,E., Rivera-de-Torre,E., Ward,A.B., Morth,J.P., Alagon,A., Mackessy,S.P., Ainsworth,S., Menzies,S.K., Casewell,N.R., Jenkins,T.P., Ljungars,A., Laustsen,A.H. (2025). Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites.
Nature,
647,
716-725.
Artículo
56 - Alfaro-Chinchilla,A., Lomonte,B., Zuniga,L., Acevedo,M., Neri-Castro,E., Alagon,A., Bonilla,F., Diaz,C., Sasa,M. (2025). Venom composition, toxicity and cross-neutralization by PoliVal-ICP antivenom, of Mesoamerican jumping pitvipers genus Metlapilcoatlus (Viperidae: Crotalinae).
Transactions of the Royal Society of Tropical Medicine and Hygiene,
119 (8),
954-970.
Artículo
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Revisión
123 - Chippaux,J.P., Boyer,L.V., Alagon,A. (2015). Post-exposure treatment of Ebola virus using passive immunotherapy: proposal for a new strategy.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
21,
3,
3.
Artículo
124 - Benard-Valle,M., Carbajal-Saucedo,A., de Roodt,A., Lopez-Vera,E., Alagon,A. (2014). Biochemical characterization of the venom of the coral snake Micrurus tener and comparative biological activities in the mouse and a reptile model.
Toxicon,
77,
6-15.
Artículo
125 - Borja,M., Castaneda,G., Espinosa,J., Neri,E., Carbajal,A., Clement,H., Garcia,O., Alagon,A. (2014). Mojave Rattlesnake (Crotalus scutulatus scutulatus) with Type B Venom from Mexico.
Copeia,
2014 (1),
7-13.
Artículo
126 - Carbajal-Saucedo,A., Floriano,R.S., Belo,C.A., Olvera-Rodriguez,A., Alagon,A., Rodrigues-Simioni,L. (2014). Neuromuscular Activity of Micrurus laticollaris (Squamata: Elapidae) Venom in Vitro.
Toxins (Basel),
6 (1),
359-370.
Artículo
127 - Castellanos-Mendoza,A., Castro-Acosta,R.M., Olvera,A., Zavala,G., Mendoza-Vera,M., Garcia-Hernandez,E., Alagon,A., Trujillo-Roldan,M.A., Valdez-Cruz,N.A. (2014). Influence of pH control in the formation of inclusion bodies during production of recombinant sphingomyelinase-D in Escherichia coli.
Microbial Cell Factories,
13 (1),
137.
Artículo
128 - de Roodt,A.R., Clement,H., Dolab,J.A., Litwin,S., Hajos,S.E., Boyer,L., Alagon,A. (2014). Protein content of antivenoms and relationship with their immunochemical reactivity and neutralization assays.
Clinical Toxicology,
52 (6),
594-603.
Artículo
129 - Diaz,P., Malave,C., Zerpa,N., Vazquez,H., D'Suze,G., Montero,Y., Castillo,C., Alagon,A., Sevcik,C. (2014). IgY pharmacokinetics in rabbits: Implications for IgY use as antivenoms.
Toxicon,
90,
124-133.
Artículo
130 - Lanari,L.C., Olvera,A., Costa de Oliveira,V, Laskowicz,R.D., Boyer,L., Lago,N.R., Alagon,A., de Roodt,A.R. (2014). Intraspecific differences in the immunochemical reactivity and neutralization of venom from Argentinean Bothrops (Rhinocerophis) alternatus by specific experimental antivenoms.
Toxicon,
85,
31-45 [corrigendum vol 88 p 138].
Artículo
131 - Sanchez-Villegas,M del C., Nazario-Santiago,C., Alagon-Cano,A., Merquez-Avila,G., Ramos-Cervantes,M.T., Loria-Castellanos,J. (2014). Cunico-epidemiological characteristics of pediatric patients with poisoning by loxosceles spiders bite.
Prensa Medica Argentina,
100 (9),
605-613.
Artículo
132 - Sanchez-Villegas,M del C., Rodriguez-Alvarez,D., Ortega-Carrillo,C., Alagon-Cano,A., Zaldivar-Cervera,J., Loria-Castellanos,J., Urzua-Rodríguez,N.A. (2014). [Systemic loxoscelism presented in a pregnant patient].
Revista Médica del Instituto Mexicano del Seguro Social,
52 (1),
98-103.
Artículo
133 - Vergara,I., Pedraza-Escalona,M., Paniagua,D., Restano-Cassulini,R., Zamudio,F., Batista,C.V., Possani,L.D., Alagon,A. (2014). Eastern coral snake Micrurus fulvius venom toxicity in mice is mainly determined by neurotoxic phospholipases A.
Journal of Proteomics,
105,
295-306.
Artículo
134 - Boyer,L., Degan,J., Ruha,A.M., Mallie,J., Mangin,E., Alagon,A. (2013). Safety of Intravenous Equine F(ab'): Insights following Clinical Trials involving 1534 Recipients of Scorpion Antivenom.
Toxicon,
76,
386-393.
Artículo
135 - Boyer,L.V., Theodorou,A.T., Chase,P.B., Osnaya,N., Berg,M., Mallie,J., Carbajal,Y., de Jesus-Hernandez,T., Olvera,F., Alagon,A. (2013). Effectiveness of Centruroides scorpion antivenom compared to historical controls.
Toxicon,
76,
377-385.
Artículo
136 - Boyer,L.V., Chase,P.B., Degan,J.A., Figge,G., Buelna-Romero,A., Luchetti,C., Alagon,A. (2013). Subacute coagulopathy in a randomized, comparative trial of Fab and F(ab') antivenoms.
Toxicon,
74,
101-108.
Artículo
137 - Low,D.H., Sunagar,K., Undheim,E.A., Ali,S.A., Alagon,A.C., Ruder,T., Jackson,T.N., Pineda-Gonzalez,S., King,G.F., Jones,A., Antunes,A., Fry,B.G. (2013). Dracula's children: Molecular evolution of vampire bat venom.
Journal of Proteomics,
89C,
95-111.
Artículo
138 - Neri-Castro,E., Lomonte,B., Gutierrez,M.C., Alagon,A., Gutierrez,J.M. (2013). Intraspecies variation in the venom of the rattlesnake Crotalus simus from Mexico: Different expression of crotoxin results in highly variable toxicity in the venoms of three subspecies.
Journal of Proteomics,
87,
103-121.
Artículo
139 - Oukkache,N., Chgoury,F., Lalaoui,M., Alagon-Cano,A., Ghalim,N. (2013). Comparison between two methods of scorpion venom milking in Morocco.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
19 (1),
5.
Artículo
140 - Vazquez,H., Olvera,F., Alagon,A., Sevcik,C. (2013). Production of anti-horse antibodies induced by IgG, F(ab') and Fab applied repeatedly to rabbits. Effect on antivenom pharmacokinetics.
Toxicon,
76,
362-369.
Artículo
141 - Clement,H., Costa de Oliveira,V, Zamudio,F.Z., Lago,N.R., Valdez-Cruz,N.A., Valle,M.B., Alagon,A.C., Possani,L.D., de Roodt,A.R. (2012). Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A(2) from Bothrops (Rhinocerophis) ammodytoides Venom.
Toxicon,
60 (7),
1314-1323.
Artículo
142 - Clement,H., Olvera,A., Rodriguez,M., Zamudio,F., Palomares,L.A., Possani,L.D., Odell,G.V., Alagon,A., Sanchez-Lopez,R. (2012). Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom.
Toxicon,
60 (7),
1223-1227.
Artículo
143 - Koludarov,I., Sunagar,K., Undheim,E.A., Jackson,T.N., Ruder,T., Whitehead,D., Saucedo,A.C., Mora,G.R., Alagon,A.C., King,G., Antunes,A., Fry,B.G. (2012). Structural and Molecular Diversification of the Anguimorpha Lizard Mandibular Venom Gland System in the Arboreal Species Abronia graminea.
Journal of Molecular Evolution,
75 (5-6),
168-183.
Artículo
144 - Paniagua,D., Jimenez,L., Romero,C., Vergara,I., Calderon,A., Benard,M., Bernas,M.J., Rilo,H., de Roodt,A., D'Suze,G., Witte,M.H., Boyer,L., Alagon,A. (2012). Lymphatic route of transport and pharmacokinetics of Micrurus fulvius (coral snake) venom in sheep.
Lymphology,
45 (4),
144-153.
Artículo
145 - Archundia,I.G., de Roodt,A.R., Ramos-Cerrillo,B., Chippaux,J.P., Olguin-Perez,L., Alagon,A., Stock,R.P. (2011). Neutralization of Vipera and Macrovipera venoms by two experimental polyvalent antisera: A study of paraspecificity.
Toxicon,
57 (7-8),
1049-1056.
Artículo
146 - Redaelli,E., Restano-Cassulini,R., Fuentes-Silva,D., Clement,H., Schiavon,E., Zamudio,F.Z., Odell,G., Arcangeli,A., Clare,J.J., Alagon,A., Rodriguez de la Vega,R.C., Possani,L.D., Wanke,E. (2010). Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.
Journal of Biological Chemistry,
285 (6),
4130-4142.
Artículo
147 - Vazquez,H., Olvera,F., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2010). Pharmacokinetics in rabbits and anti-sphingomyelinase D neutralizing power of Fab, F(ab')2, IgG and IgG(T) fragments from hyper immune equine plasma.
International Immunopharmacology,
10 (4),
447-454.
Artículo
148 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2010). Pharmacokinetics of a F(ab')(2) scorpion antivenom administered intramuscularly in healthy human volunteers.
International Immunopharmacology,
10 (11),
1318-1324.
Artículo
149 - Boyer,L.V., Theodorou,A.A., Berg,R.A., Mallie,J., Chavez-Mendez,A., Garcia-Ubbelohde,W., Hardiman,S., Alagon,A. (2009). Antivenom for critically ill children with neurotoxicity from scorpion stings.
New England Journal of Medicine,
360 (20),
2090-2098 (Reply 2009 vol 361 632).
Artículo
150 - Casasola,A., Ramos-Cerrillo,B., de Roodt,A.R., Saucedo,A.C., Chippaux,J.P., Alagon,A., Stock,R.P. (2009). Paraspecific neutralization of the venom of African species of cobra by an equine antiserum against Naja melanoleuca: A comparative study.
Toxicon,
53 (6),
602-608.
Artículo
151 - Chase,P., Boyer-Hassen,L., McNally,J., Vazquez,H.L., Theodorou,A.A., Walter,F.G., Alagon,A. (2009). Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients.
Clinical Toxicology,
47 (1),
24-28.
Artículo
152 - Corzo,G., Bernard,C., Clement,H., Villegas,E., Bosmans,F., Tytgat,J., Possani,L.D., Darbon,H., Alagon,A. (2009). Insecticidal peptides from the theraposid spider Brachypelma albiceps: A NMR-based model of Ba2.
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics,
1794 (8),
1190-1196.
Artículo
153 - Chippaux,J.P., Alagon,A. (2008). [Envenomation and poisoning by venomous or poisonous animals. VII: arachnidism in the New World].
Medecine Tropicale,
68 (3),
215-221.
Artículo
154 - Corzo,G., Diego-Garcia,E., Clement,H., Peigneur,S., Odell,G., Tytgat,J., Possani,L.D., Alagon,A. (2008). An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.
Peptides,
29 (11),
1901-1908.
Artículo
155 - Ramos-Cerrillo,B., de Roodt,A.R., Chippaux,J.P., Olguin,L., Casasola,A., Guzman,G., Paniagua-Solis,J., Alagon,A., Stock,R.P. (2008). Characterization of a new polyvalent antivenom (Antivipmyn((R)) Africa) against African vipers and elapids.
Toxicon,
52 (8),
881-888.
Artículo
156 - Chippaux,J.P., Massougbodji,A., Stock,R.P., Alagon,A. (2007). Clinical Trial of an F(ab')2 Polyvalent Equine Antivenom for African Snake Bites in Benin.
American Journal of Tropical Medicine and Hygiene,
77 (3),
538-546.
Artículo
157 - Clement,H., Odell,G., Zamudio,F.Z., Redaelli,E., Wanke,E., Alagon,A., Possani,L.D. (2007). Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels.
Toxicon,
50 (1),
65-74.
Artículo
158 - de Roodt,A.R., Estevez-Ramirez,J., Litwin,S., Magana,P., Olvera,A., Alagon,A. (2007). Toxicity of two North American Loxosceles (brown recluse spiders) venoms and their neutralization by antivenoms.
Clinical Toxicology,
45 (6),
678-687.
Carta
159 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R.P., Alagon,A., Fox,J.W. (2007). Upregulation of cytokine expression in fibroblasts exposed to Loxosceles sphingomyelinase D: What is the trigger? - Response to Moolenaar et al.
Journal of Investigative Dermatology,
127 (5),
1267-1268.
Carta
160 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R., Algaron,A., Fox,J.W. (2007). Upregulation of IL-6, IL-8, CXCL1, and CXCL2 Dominates Gene Expression in Human Fibroblast Cells Exposed to Loxosceles reclusa Sphingomyelinase D: Insights into Spider Venom Dermonecrosis.
Journal of Investigative Dermatology,
127 (5),
1264-1266.
Artículo
161 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Alagon,A. (2007). Antigenic cross-reactivity between sixteen venoms from scorpions belonging to six genera.
Clinical Toxicology,
45 (2),
158-163.
Artículo
162 - Almagro,J.C., Martinez,L., Smith,S.L., Alagon,A., Estevez,J., Paniagua,J. (2006). Analysis of the horse V(H) repertoire and comparison with the human IGHV germline genes, and sheep, cattle and pig V(H) sequences.
Molecular Immunology,
43 (11),
1836-1845.
Artículo
163 - Olvera,A., Ramos-Cerrillo,B., Estevez,J., Clement,H., de Roodt,A., Paniagua-Solis,J., Vazquez,H., Zavaleta,A., Salas-Arruz,M., Stock,R.P., Alagon,A. (2006). North and South American Loxosceles spiders: Development of a polyvalent antivenom with recombinant sphingomyelinases D as antigens.
Toxicon,
48 (1),
64-74.
Artículo
164 - de Roodt,A.R., Salomon,O.D., Orduna,T.A., Robles-Ortiz,L.E., Paniagua-Solis,J.F., Cano,A.A. (2005). Poisoning by bee sting.
Gaceta Medica de Mexico,
141 (3),
215-222.
Artículo
165 - de Roodt,A.R., Estevez-Ramirez,J., Paniagua-Solis,J.F., Litwin,S., Carvajal-Saucedo,A., Dolab,J.A., Robles-Ortiz,L.E., Alagon,A. (2005). [Toxicity of venoms from snakes of medical importance in Mexico].
Gaceta Medica de Mexico,
141 (1),
13-21.
Artículo
166 - Ramos,M.A., Sanchez-Lopez,R., Mares,R.E., Olvera,F., Alagon,A. (2005). Identification of an Entamoeba histolytica gene encoding a protein disulfide isomerase that functionally complements the dsbA mutation in Escherichia coli.
Molecular and Biochemical Parasitology,
143 (2),
236-240.
Artículo
167 - Sadurni,P., Alagon,A., Aliev,R., Burillo,G., Hoffman,A.S. (2005). Immobilization of streptavidin-horseradish peroxidase onto a biotinylated poly(acrylic acid) backbone that had been radiation-grafted to a PTFE film.
Journal of Biomaterials Science-Polymer Edition,
16 (2),
181-187.
Artículo
168 - Salgado,M., Villagomez-Castro,J.C., Rocha-Rodriguez,R., Sabanero-Lopez,M., Ramos,M.A., Alagon,A., Lopez-Romero,E., Sanchez-Lopez,R. (2005). Entamoeba histolytica: Biochemical and molecular insights into the activities within microsomal fractions.
Experimental Parasitology,
110 (4),
363-373.
Artículo
169 - Sanchez,R., Saralegui,A., Olivos-Garcia,A., Scapolla,C., Damonte,G., Sanchez-Lopez,R., Alagon,A., Stock,R.P. (2005). Entamoeba histolytica: intracellular distribution of the sec61alpha subunit of the secretory pathway and down-regulation by antisense peptide nucleic acids.
Experimental Parasitology,
109 (4),
241-251.
Artículo
170 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Mancilla-Nava,R., Paniagua-Solis,J., Alagon,A., Sevcik,C. (2005). Pharmacokinetics of a F(ab')(2) scorpion antivenom in healthy human volunteers.
Toxicon,
46 (7),
797-805.
Artículo
171 - de Roodt,A.R., Paniagua-Solis,J.F., Dolab,J.A., Estevez-Ramirez,J., Ramos-Cerrillo,B., Litwin,S., Dokmetjian,J.C., Alagon,A. (2004). Effectiveness of two common antivenoms for North, Central, and South American Micrurus envenomations.
Journal of Toxicology - Clinical Toxicology,
42 (2),
171-178.
Artículo
172 - Ramos-Cerrillo,B., Olvera,A., Odell,G.V., Zamudio,F., Paniagua-Solis,J., Alagon,A., Stock,R.P. (2004). Genetic and enzymatic characterization of sphingomyelinase D isoforms from the North American fiddleback spiders Loxosceles boneti and Loxosceles reclusa.
Toxicon,
44 (5),
507-514.
Artículo
173 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Aguilar,V., Alagon,A. (2003). Relationship between plasmatic levels of various cytokines, tumour necrosis factor, enzymes, glucose and venom concentration following Tityus scorpion sting.
Toxicon,
41 (3),
367-375.
Artículo
174 - Nieto-Sotelo,J., Martinez,L.M., Ponce,G., Cassab,G.I., Alagon,A., Meeley,R.B., Ribaut,J.M., Yang,R. (2002). Maize HSP101 Plays Important Roles in Both Induced and Basal Thermotolerance and Primary Root Growth.
Plant Cell,
14 (7),
1621-1633.
Artículo
175 - Ramos,M.A., Sanchez-Lopez,R., Olvera,F., Alagon,A. (2002). Entamoeba histolytica genomic organization: identification, structure, and phylogenetic relationship of two serine-threonine protein kinases.
Experimental Parasitology,
100 (2),
135-139.
Artículo
176 - Sanchez,R., Alagon,A., Stock,R.P. (2002). Entamoeba histolytica: intracellular distribution of the proteasome.
Experimental Parasitology,
102 (3-4),
187-190.
Artículo
177 - Juarez,P., Sanchez-Lopez,R., Stock,R.P., Olvera,A., Ramos,M.A., Alagon,A. (2001). Characterization of the Ehrab8 gene, a marker of the late stages of the secretory pathway of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
116 (2),
223-228.
Artículo
178 - Stock,R.P., Olvera,A., Sanchez,R., Saralegui,A., Scarfi,S., Sanchez-Lopez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Alagon,A. (2001). Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers.
Nature Biotechnology,
19 (3),
231-234.
Artículo
179 - Gutierrez,A., Sanchez-Lopez,R., Ramos,M.A., Alagon,A. (2000). Cloning of the Entamoeba histolytica STT3 gene, a subunit of the oligosaccharyltransferase complex.
Archives of Medical Research,
31 (4 Suppl),
S162-S164.
Artículo
180 - Juarez,P., Sanchez-Lopez,R., Ramos,M.A., Stock,R.P., Alagon,A. (2000). Rab8 as a molecular model of vesicular trafficking to investigate the latter steps of the secretory pathway in Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S157-S159.
Artículo
181 - Ramos,M.A., Alagon,A. (2000). Molecular cloning of a gene encoding a PDI-like protein from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S173-S175.
Artículo
182 - Ramos,M.A., Sanchez-Lopez,R., Alagon,A. (2000). Genomic organization of a 7 Kb gene cluster from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S263-S265.
Artículo
183 - Sanchez-Lopez,R., Siminovich,B., Alagon,A. (2000). Entamoeba histolytica codes for a protein homologue of the Sec61 alpha subunit, a component of the endoplasmic reticulum translocon.
Archives of Medical Research,
31 (4 Suppl),
S168-S170.
Artículo
184 - Sanchez-Lopez,R., Gutierrez,A., Juarez,P., Olvera,A., Olvera,F., Ramos,M.A., Sanchez,R., Saralegui,A., Stock,R.P., Alagon,A. (2000). Molecular genetics of the secretory pathway in Entamoeba histolytica: an overview.
Archives of Medical Research,
31 (4 Suppl),
S151-S152.
Artículo
185 - Stock,R.P., Olvera,A., Scarfi,S., Sanchez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Landt,O., Alagon,A. (2000). Inhibition of neomycin phosphorotransferase expression in Entamoeba histolytica with antisense peptide nucleic acid (PNA) oligomers.
Archives of Medical Research,
31 (4 Suppl),
S271-S272.
Artículo
186 - Que,X., Kim,D., Alagon,A., Hirata,K., Shike,H., Shimizu,C., Gonzalez,A., Burns,J.C., Reed,S.L. (1999). Pantropic retroviral vectors mediate gene transfer and expression in Entamoeba histolytica.
Molecular and Biochemical Parasitology,
99 (2),
237-245.
Artículo
187 - Sanchez-Gonzalez,M., Alagon,A., Rodriguez-Sotres,R., Lopez-Munguia,A. (1999). Proteolytic processing of dextransucrase of Leuconostoc mesenteroides.
Fems Microbiology Letters,
181 (1),
25-30.
Artículo
188 - Sanchez-Lopez,R., Gama-Castro,S., Ramos,M.A., Merino,E., Lizardi,P.M., Alagon,A. (1998). Cloning and expression of the Entamoeba histolytica ERD2 gene.
Molecular and Biochemical Parasitology,
92 (2),
355-359.
Artículo
189 - Vargas-Villarreal,J., Olvera-Rodriguez,A., Mata-Cardenas,B.D., Martinez-Rodriguez,H.G., Said-Fernandez,S., Alagon-Cano,A. (1998). Isolation of an Entamoeba histolytica intracellular alkaline phospholipase A(2).
Parasitology Research,
84 (4),
310-314.
Artículo; Actas Paper
Artículo
191 - Ramos,M.A., Mercado,G.C., Salgado,L.M., Sanchez-Lopez,R., Stock,R.P., Lizardi,P.M., Alagon,A. (1997). Entamoeba histolytica contains a gene encoding a homologue to the 54 kDa subunit of the signal recognition particle.
Molecular and Biochemical Parasitology,
88 (1-2),
225-235.
Artículo
192 - Ramos,M.A., Stock,R.P., Sanchez-Lopez,R., Olvera,F., Lizardi,P.M., Alagon,A. (1997). The Entamoeba histolytica proteasome alpha-subunit gene.
Molecular and Biochemical Parasitology,
84 (1),
131-135.
Artículo; Actas Paper
193 - Ramos,M.A., Stock,R.P., Lizardi,P.M., Alagon,A. (1997). The secretory pathway of Entamoeba histolytica: characterization and expression of the SRP54 gene.
Archives of Medical Research,
28 (Spec No:56-8.),
56-58.
Artículo; Actas Paper
194 - Sanchez-Lopez,R., Gama-Castro,S., Lizardi,P.M., Alagon,A. (1997). The secretory pathway of Entamoeba histolytica: characterization and expression of the ERD2 gene.
Archives of Medical Research,
28 (Spec No:59-61.),
59-61.
Artículo
195 - Estrada,G., Colin,L., Gaytan,P., Alagon,A., Lizardi,P.M. (1996). Sequence-specific detection of PCR-amplified DNA by restriction enzyme release of hybrids.
Molecular and cellular probes,
10 (3),
179-185.
Artículo
196 - Miranda,R., Salgado,L.M., Sanchez-Lopez,R., Alagon,A., Lizardi,P.M. (1996). Identification and analysis of the u6 small nuclear RNA gene from Entamoeba histolytica.
Gene,
180 (1-2),
37-42.
Artículo
197 - Ortega-Pierres,G., Alagon,A., Cortes,A., Olvera,F., Olvera,A., Gonzalez,A., Lizardi,P., Berzunza-Cruz,M., Saavedra-Lira,E., Perez-Montfort,R., Velasco-Castrejon,O., Sotero-Delgado Dominguez,I., Becker,I., Hernandez,R., Martinez-Calvillo,S., Frixione,E., Ruiz,L., Santillan,M., Vega,L., Tejero,J.M., Undeen,A.H., Kretschmer,R.R., Herion,P., Saavedra,R., Yepez-Mulia,L. (1996). [Impact of new methodologies in the study of parasites].
Gaceta Medica de Mexico,
132 (5),
475-517.
Artículo
198 - Michel,B., Lizardi,P.M., Alagon,A., Zurita,M. (1995). Identification and analysis of the start site of ribosomal RNA transcription of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
73 (1-2),
19-30.
Artículo
199 - Noeske-Jungblut,C., Haendler,B., Donner,P., Alagon,A., Possani,L., Schleuning,W.D. (1995). Triabin, a highly potent exosite inhibitor of thrombin.
Journal of Biological Chemistry,
270 (48),
28629-28634.
Artículo
200 - Noeske-Jungblut,C., Kratzschmar,J., Haendler,B., Alagon,A., Possani,L., Verhallen,P., Donner,P., Schleuning,W.D. (1994). An inhibitor of collagen-induced platelet aggregation from the saliva of Triatoma pallidipennis.
Journal of Biological Chemistry,
269 (7),
5050-5053.
Artículo
201 - Palmeros,B., Guereca,L., Alagon,A., Soberon-Chavez,G. (1994). Biochemical characterization of the lipolytic activity of pseudomonas aeruginosa IGB 83.
Process Biochemistry,
29 (3),
207-212.
Artículo
202 - Cevallos,M.A., Porta,H., Alagon,A.C., Lizardi,P.M. (1993). Sequence of the 5.8S ribosomal gene of pathogenic and non-pathogenic isolates of Entamoeba histolytica.
Nucleic Acids Research,
21 (2),
355-355.
Note
203 - Cevallos,M.A., Navarro-Duque,C., Varela-Julia,M., Alagon,A.C. (1992). Molecular mass determination and assay of venom hyaluronidases by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Toxicon,
30 (8),
925-930.
Note
204 - Michel,B., Alagon,A., Lizardi,P.M., Zurita,M. (1992). Characterization of a repetitive DNA element from Entamoeba histolytica.
Molecular and Biochemical Parasitology,
51 (1),
165-168.
Artículo
205 - Possani,L.D., Fletcher,P.L., Fletcher,M.D., Rode,G.S., Mochca-Morales,J., Lucas,S., Coronas,F.V., Alagon,A.C., Martin,B.M. (1992). Structural and functional characteristics of toxins purified from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello.
Memorias do Instituto Butantan,
54 (2),
35-52.
Artículo
206 - Schleuning,W.D., Alagon,A., Boidol,W., Bringmann,P., Petri,T., Kratzschmar,J., Haendler,B., Langer,G., Baldus,B., Witt,W. (1992). Plasminogen activators from the saliva of Desmodus rotundus (common vampire bat): unique fibrin specificity.
Annals of the New York Academy of Sciences,
667,
395-403.
*
Artículo
207 - Kratzschmar,J., Haendler,B., Langer,G., Boidol,W., Bringmann,P., Alagon,A., Donner,P., Schleuning,W.D. (1991). The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression.
Gene,
105 (2),
229-237.
Note
208 - Vargas-Villarreal,J., Martin-Polo,J.J., Reynaud,E., Alagon,A.C. (1991). A new affinity adsorbent for the purification of phospholipases A1 and A2 from animal venoms.
Toxicon,
29 (1),
119-124.
Artículo
209 - Zurita,M., Alagon,A., Vargas-Villarreal,J., Lizardi,P.M. (1991). The Entamoeba histolytica rDNA episome: nuclear localization, DNAase I sensitivity map, and specific DNA-protein interactions.
Molecular Microbiology,
5 (8),
1843-1851.
Note
210 - Laclette,J.P., Alagon,A., Willms,K., Torre-Blanco,A. (1990). Purification of antigen B from Taenia solium cysticerci by affinity to mammalian collagen.
Journal of Parasitology,
76 (2),
273-275.
Artículo
211 - Alagon,A.C., Guzman,H.S., Martin,B.M., Ramirez,A.N., Carbone,E., Possani,L.D. (1988). Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch.
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology,
89 (1),
153-161.
Artículo
212 - Alagon,A., Possani,L.D., Smart,J., Schleuning,W.D. (1986). Helodermatine, a kallikrein-like, hypotensive enzyme from the venom of Heloderma horridum horridum (Mexican beaded lizard).
Journal of Experimental Medicine,
164 (6),
1835-1845.
Artículo
213 - Sosa,B.P., Alagon,A.C., Martin,B.M., Possani,L.D. (1986). Biochemical characterization of the phospholipase A2 purified from the venom of the Mexican beaded lizard (Heloderma horridum horridum Wiegmann).
Biochemistry,
25 (10),
2927-2933.
*
Artículo
214 - King,T.P., Alagon,A.C., Kuan,J., Sobotka,A.K., Lichtenstein,L.M. (1983). Immunochemical studies of yellowjacket venom proteins.
Molecular Immunology,
20 (3),
297-308.
*
Artículo
215 - Alagon,A.C., Maldonado,M.E., Julia,J.Z., Sanchez,C.R., Possani,L.D. (1982). Venom from two sub-species of Heloderma horridum (Mexican beaded lizard): general characterization and purification of N-benzoyl-L-arginine ethyl ester hydrolase.
Toxicon,
20 (2),
463-475.
*
Artículo
216 - King,T.P., Alagon,A., Kochoumian,L., Kuan,J., Sobotka,A., Lichtenstein,L.M. (1981). Limited proteolysis of antigens E and K from ragweed pollen.
Archives of Biochemistry and Biophysics,
212 (1),
127-135.
*
Artículo
217 - Possani,L., Steinmetz,W.E., Dent,M.A., Alagon,A.C., Wuthrich,K. (1981). Preliminary spectroscopic characterization of six toxins from Latin American scorpions.
Biochimica et Biophysica Acta (BBA) - Protein Structure,
669 (2),
183-192.
*
Artículo
218 - Alagon,A.C., Molinar,R.R., Possani,L.D., Fletcher,P.L., Cronan,J.E., Julia,J.Z. (1980). Venom from the snake Bothrops asper Garman. Purification and characterization of three phospholipases A2.
Biochemical Journal,
185 (3),
695-704.
*
Artículo
219 - Alagon,A.C., King,T.P. (1980). Activation of polysaccharides with 2-iminothiolane and its uses.
Biochemistry,
19 (18),
4341-4345.
*
Note
220 - Possani,L.D., Sosa,B.P., Alagon,A.C., Burchfield,P.M. (1980). The venom from the snakes Agkistrodon bilineatus Taylori and Crotalus durissus Totonacus: lethality, biochemical and immunological properties.
Toxicon,
18 (3),
356-360.
*
Artículo
221 - Possani,L.D., Fletcher,P.L., Alagon,A.B., Alagon,A.C., Julia,J.Z. (1980). Purification and characterization of a mammalian toxin from venom of the Mexican scorpion, Centruroides limpidus tecomanus Hoffmann.
Toxicon,
18 (2),
175-183.
*
Artículo
222 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Varela,M.J., Julia,J.Z. (1979). Purification and characterization of a phospholipase A2 from the venom of the coral snake, Micrurus fulvius microgalbineus (Brown and Smith).
Biochemical Journal,
179 (3),
603-606.
*
Artículo
223 - Sosa,B.P., Alagon,A.C., Possani,L.D., Julia,J.Z. (1979). Comparison of phospholipase activity with direct and indirect lytic effects of animal venoms upon human red cells.
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry,
64 (2),
231-234.
*
Artículo
224 - King,T.P., Sobotka,A.K., Alagon,A., Kochoumian,L., Lichtenstein,L.M. (1978). Protein allergens of white-faced hornet, yellow hornet, and yellow jacket venoms.
Biochemistry,
17 (24),
5165-5174.
*
Artículo
225 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Erickson,B.W. (1977). Purification and properties of mammalian toxins from the venom of Brazilian Scorpion Tityus serrulatus Lutz and Mello.
Archives of Biochemistry and Biophysics,
180 (2),
394-403.
*
Artículo
226 - Frenk,J., Acuna,D.L., Bobadilla,J.L., Alagon,A. (1976). [Liberal medicine and institutional medicine in Mexico].
Salud Publica de Mexico,
18 (3),
481-493.
*
Nacional
227 - Sanchez-Villegas,M.C.S., Nares-Torices,M.A., Olguin-Sanchez,E., Rodriguez-Alvarez,D., Alagon-Cano,A. (2023). Loxoscelismo, envenenamiento mortal. Toxicología y monitoreo químico,biológico, radiológico y nuclear.
Colección Medicina de Excelencia IV,
157-175,
Mexico: Instituto Mexicano del Seguro Social.
Nacional
228 - Sanchez-Villegas,M.D.S., Alagon-Cano,A. (2023). Pasado y presente de los antivenenos. Toxicología y monitoreo químico,biológico, radiológico y nuclear.
Colección Medicina de Excelencia IV,
31-39,
México: Instituto Mexicano del Seguro Social.
Capítulo nacional
229 - Nares-Torices,M.A., Olguin-Sanchez,E., Rodrigues-Alvarez,D., Alagon-Cano,A., Sanchez-Villegas,M.C.S. (2021). Loxoscelismo. Una Mirada a la Toxinologia de Mexico.
35-58,
Ciudad de Mexico: Cognitio Journal.
Internacional
230 - Neri-Castro,E., Benard-Valle,M., Lopez de Leon,J., Boyer,L., Alagon,A. (2021). Envenomations by Reptiles in Mexico. Handbook of Venoms and Toxins of Reptiles 2a.
529-542,
2a.
Nacional
231 - Neri-Castro,E., Reyna,M.A., Alagon-Cano,A. (2021). Serpientes Venenosas. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
384-396,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
Nacional
232 - Reyna-Rojas,M.A., Neri-Castro,E.E., Alagon-Cano,A. (2021). Uso, manejo y percepción de herpetofauna en dos localidades del municipio de Tlaltizap án. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
398-411,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
Nacional
233 - Neri-Castro,E.E., Alagon-Cano,A. (2020). Reptiles venenosos: veneno y tratamiento. Biodiversidad en Morelos. Estudio de estado 2, vol 2.
306-310,
2,
Mexico: CONABIO.
Nacional
234 - Alagon,A. (2019). Biotecnología de antivenenos mexicana. Manos que sanan. Avances en la medicina potosina.
185-187,
San Luis Potosí, México: Graphstyle Publishers.
Internacional
235 - Paniagua, D., Vergara, I., Boyer, L., Alagon, A. (2017). Role of Lymphatic System on Snake Venom Absorption. Snake Venoms. Toxicology Series.
453-474,
Dordrecht.
Internacional
236 - Benard-Valle,M., Neri,E., Fry,B., Boyer,L., Cochran,C., Alam,M., Jackson,T.N.W., Paniagua,D., Sheira,D., Olvera-Rodriguez,F., Koludorov,I., Sunagar,K., Alagon,A. (2015). Antivenom research and development. Venomous reptiles and their toxins: Evolution, pathophysiology and biodiscovery.
61-72,
New York.
Internacional
237 - Boyer,L., Alagon,A., Fry,B.G., Jackson,T.N.W., Sunagar,K., Chippaux,J.P. (2015). Signs, symptoms and treatment of envenomation. Venomous Reptiles and Their Toxins: Evolution, Pathophysiology and Biodiscovery.
32-60,
New York: Oxford University Press.
Internacional
238 - Paniagua,D., Vergara,I., Boyer,L., Alagon,A. (2015). Role of Lymphatic System on Snake Venom Absorption. Snake Venoms.
Toxinology,
1-19.
Nacional
239 - Alagon,A., Odell,G. (2011). La biologia y taxonomia de las aranas americanas. Emergencias por Animales Ponzonosos en las Americas.
181-201,
Mexico: Instituto Bioclon & Laboratorios Silanes.
Nacional
240 - Alagon,A., Possani,L.D. (2003). Desarrollo de nuevos f rmacos a partir de la fauna tropical. Fronteras de la Biología en los Inicios del Siglo XXI, Módulo VII .
123-160,
Mexico,D.F..
Nacional
241 - Estrada,G., Sanchez,R., Lizardi,P.M., Alagon,A. (1998). Entamoeba histolytica y la reaccion en cadena de polimerasa por hibridazion y liberacion enzimatica (PCR-HERA). Biologia molecular en medicina.
Coleccion de textos politecnicos, series biotecnologicas.,
47-60,
Mexico DF.
Internacional
242 - Dehesa-Davila,M., Alagon,A.C., Possani,L.D. (1995). Clinical toxicology of scorpion stings. Handbook of clinical toxicology of animal venoms and poisons.
221-238,
New York.
Nacional
243 - Alagon,A., Carillo,C., Chavez-Haro,A., De la Mora-Zerpa,C., Larralde,C., Lamas,N, Martin,E, Osnaya-Romero,N., Perez,Y, Possani,L.D., Romero-Zamora,L. (2003). Práctica Médica Efectiva- Alacranismo (T63.2, X22).
Mexico.
Nacional revisión
244 - Neri-Castro,E., Gomez,V., Borja,M., Lopez,L.J., Alagon,A. (2025). Avances en la investigación de venenos de serpientes mexicanas y sus antivenenos: una revisión actualizada.
Toxicologia Clinica,
1 (1),
19-23.
Nacional
245 - Perez-Bautista,I., Neri-Castro,E.E., Alagon,A., Zarzosa,V., Cadena-Iniguez,J., Soto-Hernandez,M., Bravo-Vinaja,M.G., Aguiniga-Sanchez,I., Ramirez-Ramirez,I., Ruiz-Posadas,L.D. (2025). Antivenom properties of Pentalinon sp.(Apocynaceae) against the venom of Bothrops asper.
Agro Productividad,
18 (12),
171-183.
Nacional divulgacion
246 - Alagon Cano,A. (2023). Antivenenos contra animales ponzoñosos: una historia de aventuras científicas y de éxitos para México.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
32.
Nacional Case report
247 - Madrigal-Anaya,J.C., Cruz-Ibarra,A., Rodriguez-Uvalle,N.C., Gil-Alarcon,G., Alagon,A., Rodriguez-Flores,G., Boyer,L., Neri-Castro,E. (2022). A case of exotic envenomation by Naja kaouthia in Mexico.
Latin American Journal of Clinical Sciences and Medical Technology,
4,
1-8.
nacional divulgación
248 - Neri-Castro,E., Alagon-Cano,A. (2021). Descubrimientos recientes: Venenos de serpientes.
Hypatia,
66.
nacional divulgacion
Nacional Editorial
250 - Neri-Castro,E.E., Benard-Valle,M., Gil,J., Lopez de Leon J., Borja,M., Alagon,A. (2020). Serpientes venenosas en México: una revisión al estudio de los venenos, los antivenenos y la epidemiología.
Revista Latinoamericana de Herpetologia,
3 (2),
5-22.
Preprint
251 - Montes-Grajales,D., Jimenez,B., Rogel,M.A., Alagon,A., Esturau-Escofet,N., Esquivel,B., Martinez-Romero,J., Martinez-Romero,E. (2019). Nitrogen-fixing Klebsiella variicola in feces from herbivorous tortoises.
bioRxiv,
Preprint posted June 10, 2019,
666818.
Divulgación
252 - Reyna-Rojas,M.A., Garcia-Flores,A., Neri-Castro,E., Alagon-Cano,A., Monroy-Martinez,R. (2015). Conocimiento etnoherpetológico de dos comunidades aledañas a la reserva estatal sierra de montenegro, Morelos, Mexico.
Etnobiologia,
13 (2),
37-48.
Divulgación
253 - Corzo-Burguete,G., Alagon-Cano,A., Clement-Carretero,H., Jurado-Reyes,S.M., Herrera-Herrera,E. (2014). Los venenos de tar ntulas y la absorción de medicinas en nuestro cuerpo.
Hypatia,
48 (2).
Divulgación
254 - Neri-Castro,E., Benard-Valle,M., Alagon-Cano,A. (2014). Reptiles venenosos en M?xico.
Revista Digital Universitaria,
15 (11),
art 86.
Divulgación
Divulgación
256 - Alagon-Cano,A., Corzo,G., Clement-Carretero,H., Garcia-Garcia,F. (2010). Arañas: venenos con potencial biotecnológico.
Hypatia,
33.
Divulgación
257 - Rodriguez,M., Prud`Homme,M., Alagon,A., Stock,R. (2009). Expresión de a-latrotoxina Recombinante Activa de Latrodectus mactans Utilizando el Sistema de Células de Insecto-Baculovirus.
BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria,
13 (2),
34-47.
Nacional
258 - Mata-Gonzalez,M.T., Garcia-Ubbelohde,W., Alagon-Cano,A., Paniagua-Solis,J. (2008). Anticuerpos monoclonales para uso terap?utico en humanos.
Informaceutico Mexico,
15 (9-10),
30-36.
Nacional
259 - Rendon-Anaya,M., Alagon,A. (2008). Mecanismos moleculares de diversificación de inmunoglobulinas.
Revista de Educación Bioquímica,
27 (1),
19-29.
Biografía
260 - Alagon,A., Clement-Carretero,H., Lomonte,B., Gutierrez,J.M., Ownby,C.L. (2007). Obituary of George V. Odell, 1926-2006.
Toxicon,
49 (6),
886-887.
Divulgación
261 - Olvera-Rodriguez,A., Alagon-Cano,A., Ramos-Cerrillo,B., Cardoso-Torres,H.M., Olvera-Rodriguez,F. (2007). La partitura de la araña violinista: Envenenamiento fatal.
Hypatia,
22.
Editorial Material
262 - Stock,R.P., Massougbodji,A., Alagon,A., Chippaux,J.P. (2007). Bringing antivenoms to Sub-Saharan Africa.
Nature Biotechnology,
25 (2),
173-177.
News Item
263 - Chippaux,J.P., Stock,R.P., Alagon,A. (2005). Report of the 2nd international conference on envenomations in Africa (Deuxieme colloque international sur les envenomations en Afrique).
Toxicon,
46 (1),
115-118.
Divulgación
Divulgación
Divulgación
266 - Alagon,A. (2002). Anticuerpos seguros y eficaces: la revoluacion de los nuevos antivenenos.
Revista Universidad de Mexico,
617.
Divulgación
Divulgación
268 - Ramos,M.A., Alagon,A. (2001). Ruta secretoria y Entamoeba histolytica.
Mensaje Bioquimico,
25,
111-128.
Nacional
269 - Estrada-Galvan,B., Scheinvar,L., Alagon,A., Olalde-Parra,G. (2000). Resultados preliminares de electroforesis en proteínas como método auxiliar en la taxonomía de Opuntia spp.
Acta Cientifica Potosina,
15 (1),
7-24.
Nacional
Nacional
271 - Arauco,R., Alagon,A. (1979). [Propanolol in arterial hypertension. Beta-blockaders. Recent advances].
Prensa médica mexicana,
44 (5-6),
97-104.
*
272 - Alagon Cano, Alejandro (1988). Enzimas hidroliticas del veneno de heloderma horridum horridum : fosfolipasa A2 y calicreina.
Doctorado en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
273 - Alagon Cano, Alejandro (1980). Estudio sobre los venenos de varias especies zoologicas.
Instituto de Investigacions Biomedicas,
Maestria en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
Artículo
274 - Antonio-Perez,A., Clement,H., Sanchez-Lopez,R., Alagon,A., Benitez-Cardoza,C.G., Ortega-Lopez,J.. Chaperone-assisted chromatography oxidative refolding of disulfide-rich hyaluronidase from inclusion bodies.
Biotechnology and Bioprocess Engineering,
31,
783-795.
Revisión
275 - Benard-Valle,M., Ahmadi,S., Modahl,Cassandra M., Neri-Castro,E., Alagon,A., Boyer,L., Ljungars,A., Laustsen,A.H.. Large animal models for the assessment of snakebite envenoming therapies.
npj Drug Discovery,
3 (1),
12.
Artículo
276 - Cavalcante,J.S., Almeida,J.S., Coutinho,J.V.C., Neri-Castro,E., Pucca,M.B., Alagon,A., Ferreira Junior,R.S.. Translational medicine protocol for proteomics clinical research on snakebite envenoming: contributions for develop studies in mechanisms and new biomarkers.
Archives of Toxicology,
100 (4),
1617-1628.
Artículo
277 - Gonzalez-Ruiz,J.M., Huerta-Olvera,S.G., Plascencia-Jimenez,J.A., Martinez-Gallegos,E.Y., Guzman-Villalpando,J.M., Avina-Galindo,F.I., Ojeda-Vazquez,C.A., Hernandez-Munoz,E.A., Zavala-Sanchez,E.V., Vazquez-Lopez,H., Alagon,A., Banos-Hernandez,C.J.. Factors associated with clinical severity in scorpion envenomation: a retrospective cross-sectional study in western Mexico between 2021 and 2025.
Frontiers in Toxicolology,
8,
1880720.
Artículo
278 - Zarzosa,V., Vazquez-Garcia,E., Lomonte,B., Rodriguez,B., Fernandez,J., Garcia-Vazquez,U.O., Zamudio,F., Olvera-Rodriguez,A., Olvera-Rodriguez,F., Hernandez-Orihuela,L., Benard-Valle,M., Alagon,A., Neri-Castro,E.. Integrative venomics of the coral snake Micrurus elegans: composition, toxicity, and neutralization by antivenom.
Biochimie,
247 (agosto),
151-166.
Artículo
279 - Ahmadi,S., Burlet,N.J., Benard-Valle,M., Guadarrama-Martinez,A., Kerwin,S., Cardoso,I.A., Marriott,A.E., Edge,R.J., Crittenden,E., Neri-Castro,E., Fernandez-Quintero,M.L., Nguyen,G.T.T., O'Brien,C., Wouters,Y., Kalogeropoulos,K., Thumtecho,S., Ebersole,T.W., Dahl,C.H., Glegg-Sorensen,E.U., Jansen,T., Boddum,K., Manousaki,E., Rivera-de-Torre,E., Ward,A.B., Morth,J.P., Alagon,A., Mackessy,S.P., Ainsworth,S., Menzies,S.K., Casewell,N.R., Jenkins,T.P., Ljungars,A., Laustsen,A.H.. Nanobody-based recombinant antivenom for cobra, mamba and rinkhals bites.
Nature,
647,
716-725.
Artículo
280 - Alfaro-Chinchilla,A., Lomonte,B., Zuniga,L., Acevedo,M., Neri-Castro,E., Alagon,A., Bonilla,F., Diaz,C., Sasa,M.. Venom composition, toxicity and cross-neutralization by PoliVal-ICP antivenom, of Mesoamerican jumping pitvipers genus Metlapilcoatlus (Viperidae: Crotalinae).
Transactions of the Royal Society of Tropical Medicine and Hygiene,
119 (8),
954-970.
Artículo
281 - Borja,M., Castaneda-Gaytan,G., Alagon,A., Strickland,J.L., Parkinson,C., Gutierrez-Martinez,A., Rodriguez-Lopez,B., Zarzosa,V., Lomonte,B., Saviola,A.J., Fernandez,J., Smith,C.F., Hansen,K.C., Perez-Robles,A., Castaneda-Perez,S., Hirst,S.R., Olvera-Rodriguez,F., Fernandez-Badillo,L, Sigala,J, Jones,J, Montano-Rubalcava,C, Ramirez-Chaparro,R., Margres,M., Acosta-Campana,G., Neri-Castro,E.. Venom variation and ontogenetic changes in the Crotalus molossus complex: Insights into composition, activities, and antivenom neutralization.
Comparative Biochemistry and Physiology - C Toxicology and Pharmacology,
290,
110129.
Artículo
282 - Damsbo,A., Burlet,N.J., Fernandez-Quintero,M.L., Benard-Valle,M., Overath,M.D., Guadarrama-Martinez,A., Vlamynck,A., Bisbo,I., Villalobos,C., Tulika,T., Alagon,A., Loeffler,J.R., Ward,A.B., Boddum,K., Morth,J.P., Rivera-de-Torre,E., Laustsen,A.H.. Structural mechanisms behind the neutralisation of long-chain a-neurotoxins by broadly neutralising V(H)Hs discovered using a consensus antigen.
Communications Chemistry,
8 (1),
209.
Artículo
283 - Damsbo,A., Benard-Valle,M., Jansen,T., Burlet,N.J., Overath,M.D., Guadarrama-Martinez,A., Boddum,K., Alagon,A., Rivera-de-Torre,E., Laustsen,A.H.. Discovery of broadly neutralizing V(H)Hs against short-chain a-neurotoxins using a consensus toxin as an antigen.
MAbs,
17 (1),
2522838.
Artículo
284 - Seneci,L., Chandrasekara,U., Chowdhury,A., Zarzosa,V., Guadarrama-Martinez,A., Neri-Castro,E., Alagon,A., Soria,R., Fry,B.G.. The X Factor: Regional differences in the level of ontogenetic variations in procoagulant venom activity in the Northwestern Neotropical Rattlesnake (Crotalus culminatus).
Biochimie,
237,
138-149.
Artículo
285 - Zarzosa,V., Neri-Castro,E., Lomonte,B., Fernandez,J., Rodriguez-Barrera,G., Rodriguez,B., Rodriguez-Solis,A.M., Olvera-Rodriguez,A., Benard-Valle,M., Saviola,A., Garcia-Vazquez,U.O., Fernandez-Badillo,L, Morales-Capellan,N., Borja,M., Zamudio,F., Alagon,A.. Integrative transcriptomic, proteomic, biochemical and neutralization studies on the venom of Micrurus ephippifer.
Journal of Proteomics,
316,
105416.
Nacional revisión
286 - Neri-Castro,E., Gomez,V., Borja,M., Lopez,L.J., Alagon,A.. Avances en la investigación de venenos de serpientes mexicanas y sus antivenenos: una revisión actualizada.
Toxicologia Clinica,
1 (1),
19-23.
Nacional
287 - Perez-Bautista,I., Neri-Castro,E.E., Alagon,A., Zarzosa,V., Cadena-Iniguez,J., Soto-Hernandez,M., Bravo-Vinaja,M.G., Aguiniga-Sanchez,I., Ramirez-Ramirez,I., Ruiz-Posadas,L.D.. Antivenom properties of Pentalinon sp.(Apocynaceae) against the venom of Bothrops asper.
Agro Productividad,
18 (12),
171-183.
Artículo
288 - Benard-Valle,M., Wouters,Y., Ljungars,A., Nguyen,G.T.T., Ahmadi,S., Ebersole,T.W., Dahl,C.H., Guadarrama-Martinez,A., Jeppesen,F., Eriksen,H., Rodriguez-Barrera,G., Boddum,K., Jenkins,T.P., Bjorn,S.P., Schoffelen,S., Voldborg,B.G., Alagon,A., Laustsen,A.H.. In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model.
Nature Communications,
15 (1),
4310.
Artículo
289 - Bourke,L.A., Zdenek,C.N., Huynh,T.M., Hodgson,W.C., Alagon,A., Castro,E.N., Jones,J., Fry,B.G.. Fangs and Foliage: Unearthing the Haemotoxic Secrets of Cannabis-Dwelling Rattlesnakes.
Toxicon,
244,
107756.
Artículo
290 - Campbell,S.I.D., Chow,C.Y., Neri-Castro,E., Alagon,A., Gomez,A., Soria,R., King,G.F., Fry,B.G.. Taking the sting out of scorpions: Electrophysiological investigation of the relative efficacy of three antivenoms against medically significant Centruroides species.
Comparative Biochemistry and Physiology C Toxicology and Pharmacology,
283,
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291 - Dashevsky,D., Harris,R.J., Zdenek,C.N., Benard-Valle,M., Alagon,A., Portes-Junior,J.A., Tanaka-Azevedo,A.M., Grego,K.F., Sant'Anna,S.S., Frank,N., Fry,B.G.. Red-on-Yellow Queen: Bio-Layer Interferometry Reveals Functional Diversity Within Micrurus Venoms and Toxin Resistance in Prey Species.
Journal of Molecular Evolution,
92,
317-328.
Artículo
292 - Guadarrama-Martinez,A., Neri-Castro,E., Boyer,L., Alagon,A.. Variability in antivenom neutralization of Mexican viperid snake venoms.
PLoS Neglected Tropical Diseases,
18 (5),
e0012152.
Artículo
293 - Neri-Castro,E., Zarzosa,V., Lomonte,B., Zamudio,F., Hernandez-Orihuela,L., Olvera-Rodriguez,A., Rodriguez-Solis,A.M., Borja,M., Garcia-Vazquez,U.O., Jones,J.M., Parkinson,C.L., Alagon,A.. Exploring Venom Diversity in Mixcoatlus browni and Mixcoatlus barbouri: A Comparative Analysis of Two Rare Mexican Snake Species with Crotoxin-like Presence.
Biochimie,
225,
81-88.
Artículo
294 - Neri-Castro,E., Zarzosa,V., Benard-Valle,M., Rodriguez-Solis,A.M., Hernandez-Orihuela,L., Ortiz-Medina,J.A., Alagon,A.. Quantifying venom production: A study on Micrurus snakes in Mexico.
Toxicon,
240,
107658.
Artículo
295 - Olivares-Hernandez,R., Riano-Umbarila,L., Becerril,B., Alagon-Cano,A., Vazquez-Lopez,H.. Pharmacokinetic evaluation of a single chain antibody fragment against scorpion toxins in sheep.
Toxicon,
242,
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Artículo
296 - Valdez-Cruz,N.A., Rosiles-Becerril,D., Martinez-Olivares,C.E., Garcia-Hernandez,E., Cobos-Marin,L., Garzon,D., Lopez-Salas,F.E., Zavala,G., Luviano,A., Olvera,A., Alagon,A., Ramirez,O.T., Trujillo-Roldan,M.A. Oral administration of a recombinant modified RBD antigen of SARS-CoV-2 as a possible immunostimulant for the care of COVID-19.
Microbial Cell Factories,
23 (1),
41.
Artículo
297 - Zarzosa,V., Lomonte,B., Zamudio,F., Ponce-Lopez,R., Olvera-Rodriguez,F., Borja,M., Alagon,A., Neri-Castro,E.. Venom of the neotropical rattlesnake, Crotalus culminatus: Intraspecific variation, neutralization by antivenoms, and immunogenicity in rabbits.
Biochimie,
216,
160-174.
Artículo
298 - Borja,M., Neri-Castro,E., Gutierrez-Martinez,A., Bledsoe,R., Zarzosa,V., Rodriguez-Lopez,B., Strickland,J.L., Becerra-Lopez,J., Valenzuela-Ceballos,S., Parkinson,C.L., Alagon,A., Castaneda-Gaytan,G.. Ontogenetic change in the venom composition of one Mexican black-tailed rattlesnake (Crotalus molossus nigrescens) from Durango, Mexico.
Toxicon,
24,
107280.
Artículo
299 - Perez-Juarez,H., Serrano-Vazquez,A., Godinez-Alvarez,H., Gonzalez,E., Rojas-Velazquez,L., Moran,P., Portillo-Bobadilla,T., Ramiro,M., Hernandez,E., Lau,C., Martinez,M., Padilla,M.L.A., Zaragoza,M.E., Taboada,B., Palomares,L.A., Lopez,S., Alagon,A., Arias,C.F., Ximenez,C.. Longitudinal anti-SARS-CoV-2 antibody immune response in acute and convalescent patients.
Frontiers in Cellular and Infection Microbiology,
13,
1239700.
Artículo
300 - Siegrist,A.A., Boyer,L., Balchan,N.R., Vazquez,H., Alagon,A., de Roodt,A., Craig,I.S., Poulin,I.S., Timmerman,A., Trocola,D.. Outcomes of treatment of snake and scorpion envenomation in birds of prey, with and without antivenom..
Journal of Zoo and Wildlife Medicine,
53 (4),
870-881.
Nacional
301 - Sanchez-Villegas,M.C.S., Nares-Torices,M.A., Olguin-Sanchez,E., Rodriguez-Alvarez,D., Alagon-Cano,A.. Loxoscelismo, envenenamiento mortal. Toxicología y monitoreo químico,biológico, radiológico y nuclear.
Colección Medicina de Excelencia IV,
157-175,
Mexico: Instituto Mexicano del Seguro Social.
Nacional
302 - Sanchez-Villegas,M.D.S., Alagon-Cano,A.. Pasado y presente de los antivenenos. Toxicología y monitoreo químico,biológico, radiológico y nuclear.
Colección Medicina de Excelencia IV,
31-39,
México: Instituto Mexicano del Seguro Social.
Nacional divulgacion
303 - Alagon Cano,A.. Antivenenos contra animales ponzoñosos: una historia de aventuras científicas y de éxitos para México.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
32.
Artículo
304 - Colis-Torres,A., Neri-Castro,E., Strickland,J.L., Olvera-Rodriguez,A., Borja,M., Calvete,J., Jones,J., Parkinson,C.L., Banuelos,J., Lopez de Leon,J., Alagon,A.. Intraspecific venom variation of Mexican West Coast Rattlesnakes (Crotalus basiliscus) and its implications for antivenom production.
Biochimie,
192,
114-124.
Artículo
305 - Neri-Castro,E., Zarzosa,V., Colis-Torres,A., Fry,B.G., Olvera-Rodriguez,A., Jones,J., Reyes-Velazquez,J., Zamudio,F., Borja,M., Alagon,A., Lomonte,B.. Proteomic and toxicological characterization of the venoms of the most enigmatic group of rattlesnakes: The long-tailed rattlesnakes.
Biochimie,
202,
226-236.
Artículo
306 - Neri-Castro,E., Strickland,J.L., Carbajal-Marquez,R.A., Zuniga,J., Ponce-Lopez,R., Olvera,F., Alagon,A.. Characterization of the venom and external morphology of a natural hybrid between Crotalus atrox and Crotalus mictlantecuhtli.
Toxicon,
207,
43-47.
Artículo
307 - Olvera-Rodriguez,A., Amaro-Ruiz,M.G., Benard-Valle,M., Neri-Castro,E., Olvera-Rodriguez,F., Alagon,A.. Neutralization of black widow spider (Latrodectus mactans) venom with rabbit polyclonal serum hyperimmunized with recombinant alpha-latrotoxin fragments.
Biochimie,
201,
55-62.
Artículo
308 - Youngman,N.J., Carlsson,D.J., Jones,L., Neri-Castro,E., Alagon,A., Fry,B.G.. Cloud serpent coagulotoxicity: The biochemical mechanisms underpinning the anticoagulant actions of Mixcoatlus and Ophryacus venoms.
Toxicon,
211,
44-49.
Nacional Case report
309 - Madrigal-Anaya,J.C., Cruz-Ibarra,A., Rodriguez-Uvalle,N.C., Gil-Alarcon,G., Alagon,A., Rodriguez-Flores,G., Boyer,L., Neri-Castro,E.. A case of exotic envenomation by Naja kaouthia in Mexico.
Latin American Journal of Clinical Sciences and Medical Technology,
4,
1-8.
Artículo
310 - Archundia,I.G., de la Rosa,G., Olvera,F., Calderon,A., Benard-Valle,M., Alagon,A., Corzo,G.. Assessment of neutralization of Micrurus venoms with a blend of anti-Micrurus tener and anti-ScNtx antibodies.
Vaccine,
39 (6),
1000-1006.
Artículo
311 - Benard-Valle, M., Neri-Castro, E., Elizalde-Morales, N., Olvera-Rodriguez, A., Strickland, J., Acosta, G., Alagon, A.. Protein composition and biochemical characterization of venom from Sonoran Coral Snakes (Micruroides euryxanthus).
Biochimie,
182,
206-216.
Artículo
312 - Bourke, L. A., Zdenek, C. N., Neri-Castro, E., Benard-Valle, M., Alagon, A., Gutierrez, J. M., Sanchez, E. F., Aldridge, M., Fry, B. G.. Pan-American Lancehead Pit-Vipers: Coagulotoxic Venom Effects and Antivenom Neutralisation of Bothrops asper and B. atrox Geographical Variants.
Toxins (Basel),
13 (2),
78.
Artículo
313 - Dashevsky,D., Benard-Valle,M., Neri-Castro,E., Youngman,N.J., Zdenek,C.N., Alagon,A., Portes-Junior,J.A., Frank,N., Fry,B.G.. Anticoagulant Micrurus venoms: targets and neutralization.
Toxicology Letters,
337,
91-97.
Artículo
314 - de Roodt,A.R., Lanari,L.C., Ramirez,J.E., Gomez,C., Barragan,J., Litwin,S., van Grootheest,J.H., Desio,M., Dokmetjian,J.C., Dolab,J.A., Damin,C.F., Alagon,A.. Cross-reactivity of some micrurus venoms against experimental and therapeutic anti-micrurus antivenoms.
Toxicon,
200,
153-164.
Artículo
315 - Franco-Servin,C., Neri-Castro,E., Benard-Valle,M., Alagon,A., Rosales-Garcia,R.A., Guerrero-Alba,R., Poblano-Sanchez,J.E., Silva-Briano,M., Guerrero-Barrera,A.L., Sigala-Rodriguez,J.J.. Biological and Biochemical Characterization of Coronado Island Rattlesnake (Crotalus helleri caliginis) Venom and Antivenom Neutralization.
Toxins (Basel),
13 (8),
582.
Artículo
316 - Ponce-Lopez,R., Neri-Castro,E., Olvera-Rodriguez,F., Sanchez,E.E., Alagon,A., Olvera-Rodriguez,A.. Neutralization of crotamine by polyclonal antibodies generated against two whole rattlesnake venoms and a novel recombinant fusion protein.
Toxicon,
197,
70-78.
Artículo
317 - Rodrigues,C.F.B., Zdenek,C.N., Serino-Silva,C., de Morais-Zani,K., Grego,K.F., Benard-Valle,M., Neri-Castro,E., Alagon,A., Tanaka-Azevedo,A.M., Fry,B.G.. Boa g PLI from Boa constrictor Blood is a Broad-Spectrum Inhibitor of Venom PLA(2) Pathophysiological Actions.
Journal of Chemical Ecology,
47,
907-914.
Artículo
318 - Seneci,L., Zdenek,C.N., Chowdhury,A., Rodrigues,C.F.B., Neri-Castro,E., Benard-Valle,M., Alagon,A., Fry,B.G.. A Clot Twist: Extreme Variation in Coagulotoxicity Mechanisms in Mexican Neotropical Rattlesnake Venoms.
Frontiers in Immunology,
12,
612846.
Artículo
319 - Seneci,L., Zdenek,C.N., Bourke,L.A., Cochran,C., Sanchez,E.E., Neri-Castro,E., Benard-Valle,M., Alagon,A., Frank,N., Fry,B.G.. A symphony of destruction: Dynamic differential fibrinogenolytic toxicity by rattlesnake (Crotalus and Sistrurus) venoms.
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology,
245,
109034.
Capítulo nacional
320 - Nares-Torices,M.A., Olguin-Sanchez,E., Rodrigues-Alvarez,D., Alagon-Cano,A., Sanchez-Villegas,M.C.S.. Loxoscelismo. Una Mirada a la Toxinologia de Mexico.
35-58,
Ciudad de Mexico: Cognitio Journal.
Internacional
321 - Neri-Castro,E., Benard-Valle,M., Lopez de Leon,J., Boyer,L., Alagon,A.. Envenomations by Reptiles in Mexico. Handbook of Venoms and Toxins of Reptiles 2a.
529-542,
2a.
Nacional
322 - Neri-Castro,E., Reyna,M.A., Alagon-Cano,A.. Serpientes Venenosas. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
384-396,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
Nacional
323 - Reyna-Rojas,M.A., Neri-Castro,E.E., Alagon-Cano,A.. Uso, manejo y percepción de herpetofauna en dos localidades del municipio de Tlaltizap án. Diversidad biológica e importancia cultural del estado de Morelos vol 1.
398-411,
Cuernavaca: Universidad Autónoma del Estado de Morelos.
nacional divulgación
324 - Neri-Castro,E., Alagon-Cano,A.. Descubrimientos recientes: Venenos de serpientes.
Hypatia,
66.
nacional divulgacion
Artículo
326 - Benard-Valle,M., Neri-Castro,E.E., Yanez-Mendoza,M.F., Lomonte,B., Olvera,A., Zamudio,F., Restano-Cassulini,R., Possani,L.D., Jimenez-Ferrer,E., Alagon,A.. Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: Identification of the first lethal multimeric neurotoxin in coral snake venom.
Journal of Proteomics,
225,
103863.
Artículo
327 - Braga,J.R.M., Jorge,A.R.C., Marinho,A.D., de Moraes Silveira,J.A., Nogueira-Junior,F.A., Benard-Valle,M., Alagon,A., de Menezes,R.R.P.P., Martins,A.M.C., Feijao,L.X., Monteiro,H.S.A., Jorge,R.J.B.. Renal effects of venoms of Mexican coral snakes Micrurus browni and Micrurus laticollaris.
Toxicon,
181,
45-52.
Artículo
328 - Chippaux,J.P., Celis,A., Boyer,L., Alagon,A.. Factors involved in the resilience of incidence and decrease of mortality from scorpion stings in Mexico.
Toxicon,
188,
65-75.
Artículo
329 - Garcia-Osorio,B., Lomonte,B., Benard-Valle,M., Lopez de Leon J., Roman-Dominguez,L., Mejia-Dominguez,N., Lara-Hernandez,F., Alagon,A., Neri-Castro,E.. Ontogenetic changes in the venom of Metlapilcoatlus nummifer, the Mexican jumping viper.
Toxicon,
184,
204-214.
Artículo
330 - Grashof,D., Zdenek,C.N., Dobson,J.S., Youngman,N.J., Coimbra,F., Benard-Valle,M., Alagon,A., Fry,B.G.. A Web of Coagulotoxicity: Failure of Antivenom to Neutralize the Destructive (Non-Clotting) Fibrinogenolytic Activity of Loxosceles and Sicarius Spider Venoms.
Toxins (Basel),
12 (2).
Artículo
331 - Neri-Castro,E., Benard-Valle,M., Paniagua,D., Boyer,L.V., Possani,D., Lopez-Casillas,F., Olvera,A., Romero,C., Zamudio,F., Alagon,A.. Neotropical Rattlesnake (Crotalus simus) Venom Pharmacokinetics in Lymph and Blood Using an Ovine Model.
Toxins (Basel),
12 (7),
455.
Artículo
332 - Neri-Castro,E., Sanz,L., Olvera-Rodriguez,A., Benard-Valle,M., Alagon,A., Calvete,J.J.. Venomics and biochemical analysis of the black-tailed horned pitviper, Mixcoatlus melanurus, and characterization of Melanurutoxin, a novel crotoxin homolog.
Journal of Proteomics,
225,
103865.
Artículo
333 - Paniagua,D., Crowns,K., Montonera,M., Wertheimer,A., Alagon,A., Boyer,L.. Postmortem histopathology and detection of venom by ELISA following suicide by cobra (Naja kaouthia) envenomation.
Forensic Toxicology,
38 (2),
523-528.
Artículo
334 - Ponce-Lopez,R., Neri-Castro,E., Borja,M., Strickland,J.L., Alagon,A.. Neutralizing potency and immunochemical evaluation of an anti-Crotalus mictlantecuhtli experimental serum.
Toxicon,
187,
171-180.
Artículo
335 - Rivas-Mercado E., Neri-Castro E., Benard-Valle M., Rucavado-Romero,A., Olvera-Rodriguez A., Zamudio-Zuniga F., Alagon,A., Garza-Ocanas L.. Disintegrins extracted from totonacan rattlesnake (Crotalus totonacus) venom and their anti-adhesive and anti-migration effects on MDA-MB-231 and HMEC-1 cells.
Toxicology in Vitro,
65,
104809.
Artículo
336 - Sanchez,M., Solano,G., Vargas,M., Reta-Mares,F., Neri-Castro,E., Alagon,A., Sanchez,A., Villalta,M., Leon,G., Segura,A.. Toxicological profile of medically relevant Crotalus species from Mexico and their neutralization by a Crotalus basiliscus/Bothrops asper antivenom.
Toxicon,
179,
92-100.
Nacional
337 - Neri-Castro,E.E., Alagon-Cano,A.. Reptiles venenosos: veneno y tratamiento. Biodiversidad en Morelos. Estudio de estado 2, vol 2.
306-310,
2,
Mexico: CONABIO.
Nacional Editorial
338 - Neri-Castro,E.E., Benard-Valle,M., Gil,J., Lopez de Leon J., Borja,M., Alagon,A.. Serpientes venenosas en México: una revisión al estudio de los venenos, los antivenenos y la epidemiología.
Revista Latinoamericana de Herpetologia,
3 (2),
5-22.
Artículo
339 - de la Rosa,G., Olvera,F., Archundia,I.G., Lomonte,B., Alagon,A., Corzo,G.. Horse immunization with short-chain consensus a-neurotoxin generates antibodies against broad spectrum of elapid venomous species.
Nature Communications,
10 (1),
3642.
Artículo
340 - Kakumanu,R., Hodgson,W.C., Ravi,R., Alagon,A., Harris,R.J., Brust,A., Alewood,P.F., Kemp-Harper,B.K., Fry,B.G.. Vampire Venom: Vasodilatory Mechanisms of Vampire Bat (Desmodus rotundus) Blood Feeding.
Toxins (Basel),
11 (1),
26.
Artículo
341 - Neri-Castro, E., Lomonte, B., Valdes, M., Ponce-Lopez, R., Benard-Valle, M., Borja, M., Strickland, J. L., Jones, J. M., Grunwald, C., Zamudio, F., Alagon, A.. Venom characterization of the three species of Ophryacus and proteomic profiling of O. sphenophrys unveils Sphenotoxin, a novel Crotoxin-like heterodimeric beta-neurotoxin.
Journal of Proteomics,
192,
196-207.
Artículo
342 - Neri-Castro,E., Hernandez-Davila,A., Olvera-Rodriguez,A., Cardoso-Torres,H., Benard-Valle,M., Bastiaans,E., Lopez-Gutierrez,O., Alagon,A.. Detection and quantification of a á-neurotoxin (crotoxin homologs) in the venom of the rattlesnakes Crotalus simus, C. culminatus and C. tzabcan from Mexico.
Toxicon X,
2,
100007.
Artículo
343 - Paniagua,D., Vergara,I., Roman,R., Romero,C., Benard-Valle,M., Calderon,A., Jimenez,L., Bernas,M.J., Witte,M.H., Boyer,L.V., Alagon,A.. Antivenom effect on lymphatic absorption and pharmacokinetics of coral snake venom using a large animal model.
Clinical Toxicology,
57 (8),
727-734.
Artículo
344 - Roman-Dominguez,L., Neri-Castro,E., Vazquez-Lopez,H., Garcia-Osorio,B., Archundia,I.G., Ortiz-Medina,J.A., Petricevich,V.L., Alagon,A., Benard-Valle,M.. Biochemical and immunochemical characterization of venoms from snakes of the genus Agkistrodon.
Toxicon X,
4,
100013.
Nacional
345 - Alagon,A.. Biotecnología de antivenenos mexicana. Manos que sanan. Avances en la medicina potosina.
185-187,
San Luis Potosí, México: Graphstyle Publishers.
Preprint
346 - Montes-Grajales,D., Jimenez,B., Rogel,M.A., Alagon,A., Esturau-Escofet,N., Esquivel,B., Martinez-Romero,J., Martinez-Romero,E.. Nitrogen-fixing Klebsiella variicola in feces from herbivorous tortoises.
bioRxiv,
Preprint posted June 10, 2019,
666818.
Artículo
347 - Borja, M., Neri-Castro, E., Castaneda-Gaytan, G., Strickland, J.L., Parkinson, C.L., Castaneda-Gaytan, J., Ponce-Lopez, R., Lomonte, B., Olvera-Rodriguez, A., Alagon, A., Perez-Morales, R.. Biological and Proteolytic Variation in the Venom of Crotalus scutulatus scutulatus from Mexico.
Toxins (Basel),
10 (1),
35.
Artículo
348 - Borja,M., Neri-Castro,E., Perez-Morales,R., Strickland,J.L., Ponce-Lopez,R., Parkinson,C.L., Espinosa-Fematt,J., Saenz-Mata,J., Flores-Martinez,E., Alagon,A., Castaneda-Gaytan,G.. Ontogenetic Change in the Venom of Mexican Black-Tailed Rattlesnakes (Crotalus molossus nigrescens).
Toxins (Basel),
10 (12).
Artículo
349 - Calcines-Cruz, C., Olvera, A., Castro-Acosta, R.M., Zavala, G., Alagon, A., Trujillo-Roldan, M.A., Valdez-Cruz, N.A.. Recombinant-phospholipase A2 production and architecture of inclusion bodies are affected by pH in Escherichia coli.
International Journal of Biological Macromolecules,
108,
826-836.
Artículo
350 - Dobson, J., Yang, D., Op den, Brouw B., Cochran, C., Huynh, T., Kurrupu, S., Sanchez, E.E., Massey, D.J., Baumann, K., Jackson, T.N.W., Nouwens, A., Josh, P., Neri-Castro, E., Alagon, A., Hodgson, W.C., Fry, B.G.. Rattling the border wall: Pathophysiological implications of functional and proteomic venom variation between Mexican and US subspecies of the desert rattlesnake Crotalus scutulatus.
Comparative Biochemistry and Physiology C Toxicology and Pharmacology,
205,
62-69.
Artículo
351 - Guerrero-Garzon, J.F., Benard-Valle, M., Restano-Cassulini, R., Zamudio, F., Corzo, G., Alagon, A., Olvera-Rodriguez, A.. Cloning and sequencing of three-finger toxins from the venom glands of four Micrurus species from Mexico and heterologous expression of an alpha-neurotoxin from Micrurus diastema.
Biochimie,
147,
114-121.
Artículo
352 - de la Rosa G., Pastor, N., Alagon, A., Corzo, G.. Synthetic peptide antigens derived from long-chain alpha-neurotoxins: Immunogenicity effect against elapid venoms.
Peptides,
88,
80-86.
Artículo
353 - Durban, J., Sanz, L., Trevisan-Silva, D., Neri-Castro, E., Alagon, A., Calvete, J.J.. Integrated venomics and venom gland transcriptome analysis of juvenile and adult Mexican rattlesnakes Crotalus simus, C. tzabcan and C. culminatus revealed miRNA-modulated ontogenetic shifts.
Journal of Proteome Research,
16 (9),
3370-3390.
Artículo
354 - Hernandez-Vargas, M.J., Gil, J., Lozano, L., Pedraza-Escalona, M., Ortiz, E., Encarnacion-Guevara, S., Alagon, A., Corzo, G.. Proteomic and transcriptomic analysis of saliva components from the hematophagous reduviid Triatoma pallidipennis.
Journal of Proteomics,
162,
30-39.
Artículo
355 - Rivas, E., Neri-Castro, E., Benard-Valle, M., Hernandez-Davila, A.I., Zamudio, F., Alagon, A.. General characterization of the venoms from two species of rattlesnakes and an intergrade population (C. lepidus x aquilus) from Aguascalientes and Zacatecas, Mexico.
Toxicon,
138,
191-195.
Artículo
356 - Valdez-Cruz, N.A., Reynoso-Cereceda, G.I., Perez-Rodriguez, S., Restrepo-Pineda, S., Gonzalez-Santana, J., Olvera, A., Zavala, G., Alagon, A., Trujillo-Roldan, M.A.. Production of a recombinant phospholipase A2 in Escherichia coli using resonant acoustic mixing that improves oxygen transfer in shake flasks.
Microbial Cell Factories,
16 (1),
129.
Artículo
357 - Yang, D.C., Dobson, J., Cochran, C., Dashevsky, D., Arbuckle, K., Benard, M., Boyer, L., Alagon, A., Hendrikx, I., Hodgson, W.C., Fry, B.G.. The Bold and the Beautiful: a Neurotoxicity Comparison of New World Coral Snakes in the Micruroides and Micrurus Genera and Relative Neutralization by Antivenom.
Neurotoxicity Research,
32 (3),
487-495.
Internacional
358 - Paniagua, D., Vergara, I., Boyer, L., Alagon, A.. Role of Lymphatic System on Snake Venom Absorption. Snake Venoms. Toxicology Series.
453-474,
Dordrecht.
Artículo
359 - Clement,H., Flores,V., de la Rosa,G., Zamudio,F., Alagon,A., Corzo,G.. Heterologous expression, protein folding and antibody recognition of a neurotoxin from the Mexican coral snake Micrurus laticorallis.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
22 (1),
25.
Revisión
360 - Lomonte,B., Rey-Suarez,P., Fernandez,J., Sasa,M., Pla,D., Vargas,N., Benard-Valle,M., Sanz,L., Correa-Netto,C., Nunez,V., Alape-Giron,A., Alagon,A., Gutierrez,J.M., Calvete,J.J.. Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses.
Toxicon,
122,
7-25.
Artículo
361 - Olvera,F., Rosales,A., Olvera,A., Diaz,P., Sevcik,C., Salazar,V., Alagon,A., Hernandez,H., D'Suze,G.. An efficient approach to clone and express active Neopladine 2, an anticancer peptide from Tityus discrepans scorpion venom.
Process Biochemistry,
51 (5),
624-631.
Artículo
362 - Vergara,I., Castillo,E.Y., Romero-Pina,M.E., Torres-Viquez,I., Paniagua,D., Boyer,L.V., Alagon,A., Medina,L.A.. Biodistribution and Lymphatic Tracking of the Main Neurotoxin of Micrurus fulvius Venom by Molecular Imaging.
Toxins (Basel),
8 (4),
85.
Artículo
363 - Bush,S.P., Ruha,A.M., Seifert,S.A., Morgan,D.L., Lewis,B.J., Arnold,T.C., Clark,R.F., Meggs,W.J., Toschlog,E.A., Borron,S.W., Figge,G.R., Sollee,D.R., Shirazi,F.M., Wolk,R., de Chazal,I, Quan,D., Garcia-Ubbelohde,W., Alagon,A., Gerkin,R.D., Boyer,L.V.. Comparison of F(ab') versus Fab antivenom for pit viper envenomation: A prospective, blinded, multicenter, randomized clinical trial.
Clinical Toxicology,
53 (1),
37-45.
Revisión
364 - Chippaux,J.P., Boyer,L.V., Alagon,A.. Post-exposure treatment of Ebola virus using passive immunotherapy: proposal for a new strategy.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
21,
3,
3.
Internacional
365 - Benard-Valle,M., Neri,E., Fry,B., Boyer,L., Cochran,C., Alam,M., Jackson,T.N.W., Paniagua,D., Sheira,D., Olvera-Rodriguez,F., Koludorov,I., Sunagar,K., Alagon,A.. Antivenom research and development. Venomous reptiles and their toxins: Evolution, pathophysiology and biodiscovery.
61-72,
New York.
Internacional
366 - Boyer,L., Alagon,A., Fry,B.G., Jackson,T.N.W., Sunagar,K., Chippaux,J.P.. Signs, symptoms and treatment of envenomation. Venomous Reptiles and Their Toxins: Evolution, Pathophysiology and Biodiscovery.
32-60,
New York: Oxford University Press.
Internacional
367 - Paniagua,D., Vergara,I., Boyer,L., Alagon,A.. Role of Lymphatic System on Snake Venom Absorption. Snake Venoms.
Toxinology,
1-19.
Divulgación
368 - Reyna-Rojas,M.A., Garcia-Flores,A., Neri-Castro,E., Alagon-Cano,A., Monroy-Martinez,R.. Conocimiento etnoherpetológico de dos comunidades aledañas a la reserva estatal sierra de montenegro, Morelos, Mexico.
Etnobiologia,
13 (2),
37-48.
Artículo
369 - Benard-Valle,M., Carbajal-Saucedo,A., de Roodt,A., Lopez-Vera,E., Alagon,A.. Biochemical characterization of the venom of the coral snake Micrurus tener and comparative biological activities in the mouse and a reptile model.
Toxicon,
77,
6-15.
Artículo
370 - Borja,M., Castaneda,G., Espinosa,J., Neri,E., Carbajal,A., Clement,H., Garcia,O., Alagon,A.. Mojave Rattlesnake (Crotalus scutulatus scutulatus) with Type B Venom from Mexico.
Copeia,
2014 (1),
7-13.
Artículo
371 - Carbajal-Saucedo,A., Floriano,R.S., Belo,C.A., Olvera-Rodriguez,A., Alagon,A., Rodrigues-Simioni,L.. Neuromuscular Activity of Micrurus laticollaris (Squamata: Elapidae) Venom in Vitro.
Toxins (Basel),
6 (1),
359-370.
Artículo
372 - Castellanos-Mendoza,A., Castro-Acosta,R.M., Olvera,A., Zavala,G., Mendoza-Vera,M., Garcia-Hernandez,E., Alagon,A., Trujillo-Roldan,M.A., Valdez-Cruz,N.A.. Influence of pH control in the formation of inclusion bodies during production of recombinant sphingomyelinase-D in Escherichia coli.
Microbial Cell Factories,
13 (1),
137.
Artículo
373 - de Roodt,A.R., Clement,H., Dolab,J.A., Litwin,S., Hajos,S.E., Boyer,L., Alagon,A.. Protein content of antivenoms and relationship with their immunochemical reactivity and neutralization assays.
Clinical Toxicology,
52 (6),
594-603.
Artículo
374 - Diaz,P., Malave,C., Zerpa,N., Vazquez,H., D'Suze,G., Montero,Y., Castillo,C., Alagon,A., Sevcik,C.. IgY pharmacokinetics in rabbits: Implications for IgY use as antivenoms.
Toxicon,
90,
124-133.
Artículo
375 - Lanari,L.C., Olvera,A., Costa de Oliveira,V, Laskowicz,R.D., Boyer,L., Lago,N.R., Alagon,A., de Roodt,A.R.. Intraspecific differences in the immunochemical reactivity and neutralization of venom from Argentinean Bothrops (Rhinocerophis) alternatus by specific experimental antivenoms.
Toxicon,
85,
31-45 [corrigendum vol 88 p 138].
Artículo
376 - Sanchez-Villegas,M del C., Nazario-Santiago,C., Alagon-Cano,A., Merquez-Avila,G., Ramos-Cervantes,M.T., Loria-Castellanos,J.. Cunico-epidemiological characteristics of pediatric patients with poisoning by loxosceles spiders bite.
Prensa Medica Argentina,
100 (9),
605-613.
Artículo
377 - Sanchez-Villegas,M del C., Rodriguez-Alvarez,D., Ortega-Carrillo,C., Alagon-Cano,A., Zaldivar-Cervera,J., Loria-Castellanos,J., Urzua-Rodríguez,N.A.. [Systemic loxoscelism presented in a pregnant patient].
Revista Médica del Instituto Mexicano del Seguro Social,
52 (1),
98-103.
Artículo
378 - Vergara,I., Pedraza-Escalona,M., Paniagua,D., Restano-Cassulini,R., Zamudio,F., Batista,C.V., Possani,L.D., Alagon,A.. Eastern coral snake Micrurus fulvius venom toxicity in mice is mainly determined by neurotoxic phospholipases A.
Journal of Proteomics,
105,
295-306.
Divulgación
379 - Corzo-Burguete,G., Alagon-Cano,A., Clement-Carretero,H., Jurado-Reyes,S.M., Herrera-Herrera,E.. Los venenos de tar ntulas y la absorción de medicinas en nuestro cuerpo.
Hypatia,
48 (2).
Divulgación
380 - Neri-Castro,E., Benard-Valle,M., Alagon-Cano,A.. Reptiles venenosos en M?xico.
Revista Digital Universitaria,
15 (11),
art 86.
Artículo
381 - Boyer,L., Degan,J., Ruha,A.M., Mallie,J., Mangin,E., Alagon,A.. Safety of Intravenous Equine F(ab'): Insights following Clinical Trials involving 1534 Recipients of Scorpion Antivenom.
Toxicon,
76,
386-393.
Artículo
382 - Boyer,L.V., Theodorou,A.T., Chase,P.B., Osnaya,N., Berg,M., Mallie,J., Carbajal,Y., de Jesus-Hernandez,T., Olvera,F., Alagon,A.. Effectiveness of Centruroides scorpion antivenom compared to historical controls.
Toxicon,
76,
377-385.
Artículo
383 - Boyer,L.V., Chase,P.B., Degan,J.A., Figge,G., Buelna-Romero,A., Luchetti,C., Alagon,A.. Subacute coagulopathy in a randomized, comparative trial of Fab and F(ab') antivenoms.
Toxicon,
74,
101-108.
Artículo
384 - Low,D.H., Sunagar,K., Undheim,E.A., Ali,S.A., Alagon,A.C., Ruder,T., Jackson,T.N., Pineda-Gonzalez,S., King,G.F., Jones,A., Antunes,A., Fry,B.G.. Dracula's children: Molecular evolution of vampire bat venom.
Journal of Proteomics,
89C,
95-111.
Artículo
385 - Neri-Castro,E., Lomonte,B., Gutierrez,M.C., Alagon,A., Gutierrez,J.M.. Intraspecies variation in the venom of the rattlesnake Crotalus simus from Mexico: Different expression of crotoxin results in highly variable toxicity in the venoms of three subspecies.
Journal of Proteomics,
87,
103-121.
Artículo
386 - Oukkache,N., Chgoury,F., Lalaoui,M., Alagon-Cano,A., Ghalim,N.. Comparison between two methods of scorpion venom milking in Morocco.
Journal of Venomous Animals and Toxins Including Tropical Diseases,
19 (1),
5.
Artículo
387 - Vazquez,H., Olvera,F., Alagon,A., Sevcik,C.. Production of anti-horse antibodies induced by IgG, F(ab') and Fab applied repeatedly to rabbits. Effect on antivenom pharmacokinetics.
Toxicon,
76,
362-369.
Divulgación
Artículo
389 - Clement,H., Costa de Oliveira,V, Zamudio,F.Z., Lago,N.R., Valdez-Cruz,N.A., Valle,M.B., Alagon,A.C., Possani,L.D., de Roodt,A.R.. Isolation, amino acid sequence and biological characterization of an "aspartic-49" phospholipase A(2) from Bothrops (Rhinocerophis) ammodytoides Venom.
Toxicon,
60 (7),
1314-1323.
Artículo
390 - Clement,H., Olvera,A., Rodriguez,M., Zamudio,F., Palomares,L.A., Possani,L.D., Odell,G.V., Alagon,A., Sanchez-Lopez,R.. Identification, cDNA cloning and heterologous expression of a hyaluronidase from the tarantula Brachypelma vagans venom.
Toxicon,
60 (7),
1223-1227.
Artículo
391 - Koludarov,I., Sunagar,K., Undheim,E.A., Jackson,T.N., Ruder,T., Whitehead,D., Saucedo,A.C., Mora,G.R., Alagon,A.C., King,G., Antunes,A., Fry,B.G.. Structural and Molecular Diversification of the Anguimorpha Lizard Mandibular Venom Gland System in the Arboreal Species Abronia graminea.
Journal of Molecular Evolution,
75 (5-6),
168-183.
Artículo
392 - Paniagua,D., Jimenez,L., Romero,C., Vergara,I., Calderon,A., Benard,M., Bernas,M.J., Rilo,H., de Roodt,A., D'Suze,G., Witte,M.H., Boyer,L., Alagon,A.. Lymphatic route of transport and pharmacokinetics of Micrurus fulvius (coral snake) venom in sheep.
Lymphology,
45 (4),
144-153.
Artículo
393 - Archundia,I.G., de Roodt,A.R., Ramos-Cerrillo,B., Chippaux,J.P., Olguin-Perez,L., Alagon,A., Stock,R.P.. Neutralization of Vipera and Macrovipera venoms by two experimental polyvalent antisera: A study of paraspecificity.
Toxicon,
57 (7-8),
1049-1056.
Nacional
394 - Alagon,A., Odell,G.. La biologia y taxonomia de las aranas americanas. Emergencias por Animales Ponzonosos en las Americas.
181-201,
Mexico: Instituto Bioclon & Laboratorios Silanes.
Artículo
395 - Redaelli,E., Restano-Cassulini,R., Fuentes-Silva,D., Clement,H., Schiavon,E., Zamudio,F.Z., Odell,G., Arcangeli,A., Clare,J.J., Alagon,A., Rodriguez de la Vega,R.C., Possani,L.D., Wanke,E.. Target promiscuity and heterogeneous effects of tarantula venom peptides affecting Na+ and K+ ion channels.
Journal of Biological Chemistry,
285 (6),
4130-4142.
Artículo
396 - Vazquez,H., Olvera,F., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics in rabbits and anti-sphingomyelinase D neutralizing power of Fab, F(ab')2, IgG and IgG(T) fragments from hyper immune equine plasma.
International Immunopharmacology,
10 (4),
447-454.
Artículo
397 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics of a F(ab')(2) scorpion antivenom administered intramuscularly in healthy human volunteers.
International Immunopharmacology,
10 (11),
1318-1324.
Divulgación
398 - Alagon-Cano,A., Corzo,G., Clement-Carretero,H., Garcia-Garcia,F.. Arañas: venenos con potencial biotecnológico.
Hypatia,
33.
Artículo
399 - Boyer,L.V., Theodorou,A.A., Berg,R.A., Mallie,J., Chavez-Mendez,A., Garcia-Ubbelohde,W., Hardiman,S., Alagon,A.. Antivenom for critically ill children with neurotoxicity from scorpion stings.
New England Journal of Medicine,
360 (20),
2090-2098 (Reply 2009 vol 361 632).
Artículo
400 - Casasola,A., Ramos-Cerrillo,B., de Roodt,A.R., Saucedo,A.C., Chippaux,J.P., Alagon,A., Stock,R.P.. Paraspecific neutralization of the venom of African species of cobra by an equine antiserum against Naja melanoleuca: A comparative study.
Toxicon,
53 (6),
602-608.
Artículo
401 - Chase,P., Boyer-Hassen,L., McNally,J., Vazquez,H.L., Theodorou,A.A., Walter,F.G., Alagon,A.. Serum levels and urine detection of Centruroides sculpturatus venom in significantly envenomated patients.
Clinical Toxicology,
47 (1),
24-28.
Artículo
402 - Corzo,G., Bernard,C., Clement,H., Villegas,E., Bosmans,F., Tytgat,J., Possani,L.D., Darbon,H., Alagon,A.. Insecticidal peptides from the theraposid spider Brachypelma albiceps: A NMR-based model of Ba2.
Biochimica et Biophysica Acta (BBA) - Proteins & Proteomics,
1794 (8),
1190-1196.
Divulgación
403 - Rodriguez,M., Prud`Homme,M., Alagon,A., Stock,R.. Expresión de a-latrotoxina Recombinante Activa de Latrodectus mactans Utilizando el Sistema de Células de Insecto-Baculovirus.
BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria,
13 (2),
34-47.
Artículo
404 - Chippaux,J.P., Alagon,A.. [Envenomation and poisoning by venomous or poisonous animals. VII: arachnidism in the New World].
Medecine Tropicale,
68 (3),
215-221.
Artículo
405 - Corzo,G., Diego-Garcia,E., Clement,H., Peigneur,S., Odell,G., Tytgat,J., Possani,L.D., Alagon,A.. An insecticidal peptide from the theraposid Brachypelma smithi spider venom reveals common molecular features among spider species from different genera.
Peptides,
29 (11),
1901-1908.
Artículo
406 - Ramos-Cerrillo,B., de Roodt,A.R., Chippaux,J.P., Olguin,L., Casasola,A., Guzman,G., Paniagua-Solis,J., Alagon,A., Stock,R.P.. Characterization of a new polyvalent antivenom (Antivipmyn((R)) Africa) against African vipers and elapids.
Toxicon,
52 (8),
881-888.
Nacional
407 - Mata-Gonzalez,M.T., Garcia-Ubbelohde,W., Alagon-Cano,A., Paniagua-Solis,J.. Anticuerpos monoclonales para uso terap?utico en humanos.
Informaceutico Mexico,
15 (9-10),
30-36.
Nacional
408 - Rendon-Anaya,M., Alagon,A.. Mecanismos moleculares de diversificación de inmunoglobulinas.
Revista de Educación Bioquímica,
27 (1),
19-29.
Artículo
409 - Chippaux,J.P., Massougbodji,A., Stock,R.P., Alagon,A.. Clinical Trial of an F(ab')2 Polyvalent Equine Antivenom for African Snake Bites in Benin.
American Journal of Tropical Medicine and Hygiene,
77 (3),
538-546.
Artículo
410 - Clement,H., Odell,G., Zamudio,F.Z., Redaelli,E., Wanke,E., Alagon,A., Possani,L.D.. Isolation and characterization of a novel toxin from the venom of the spider Grammostola rosea that blocks sodium channels.
Toxicon,
50 (1),
65-74.
Artículo
411 - de Roodt,A.R., Estevez-Ramirez,J., Litwin,S., Magana,P., Olvera,A., Alagon,A.. Toxicity of two North American Loxosceles (brown recluse spiders) venoms and their neutralization by antivenoms.
Clinical Toxicology,
45 (6),
678-687.
Carta
412 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R.P., Alagon,A., Fox,J.W.. Upregulation of cytokine expression in fibroblasts exposed to Loxosceles sphingomyelinase D: What is the trigger? - Response to Moolenaar et al.
Journal of Investigative Dermatology,
127 (5),
1267-1268.
Carta
413 - Dragulev,B., Bao,Y., Ramos-Cerrillo,B., Vazquez,H., Olvera,A., Stock,R., Algaron,A., Fox,J.W.. Upregulation of IL-6, IL-8, CXCL1, and CXCL2 Dominates Gene Expression in Human Fibroblast Cells Exposed to Loxosceles reclusa Sphingomyelinase D: Insights into Spider Venom Dermonecrosis.
Journal of Investigative Dermatology,
127 (5),
1264-1266.
Artículo
414 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Alagon,A.. Antigenic cross-reactivity between sixteen venoms from scorpions belonging to six genera.
Clinical Toxicology,
45 (2),
158-163.
Biografía
415 - Alagon,A., Clement-Carretero,H., Lomonte,B., Gutierrez,J.M., Ownby,C.L.. Obituary of George V. Odell, 1926-2006.
Toxicon,
49 (6),
886-887.
Divulgación
416 - Olvera-Rodriguez,A., Alagon-Cano,A., Ramos-Cerrillo,B., Cardoso-Torres,H.M., Olvera-Rodriguez,F.. La partitura de la araña violinista: Envenenamiento fatal.
Hypatia,
22.
Editorial Material
417 - Stock,R.P., Massougbodji,A., Alagon,A., Chippaux,J.P.. Bringing antivenoms to Sub-Saharan Africa.
Nature Biotechnology,
25 (2),
173-177.
Artículo
418 - Almagro,J.C., Martinez,L., Smith,S.L., Alagon,A., Estevez,J., Paniagua,J.. Analysis of the horse V(H) repertoire and comparison with the human IGHV germline genes, and sheep, cattle and pig V(H) sequences.
Molecular Immunology,
43 (11),
1836-1845.
Artículo
419 - Olvera,A., Ramos-Cerrillo,B., Estevez,J., Clement,H., de Roodt,A., Paniagua-Solis,J., Vazquez,H., Zavaleta,A., Salas-Arruz,M., Stock,R.P., Alagon,A.. North and South American Loxosceles spiders: Development of a polyvalent antivenom with recombinant sphingomyelinases D as antigens.
Toxicon,
48 (1),
64-74.
Artículo
420 - de Roodt,A.R., Salomon,O.D., Orduna,T.A., Robles-Ortiz,L.E., Paniagua-Solis,J.F., Cano,A.A.. Poisoning by bee sting.
Gaceta Medica de Mexico,
141 (3),
215-222.
Artículo
421 - de Roodt,A.R., Estevez-Ramirez,J., Paniagua-Solis,J.F., Litwin,S., Carvajal-Saucedo,A., Dolab,J.A., Robles-Ortiz,L.E., Alagon,A.. [Toxicity of venoms from snakes of medical importance in Mexico].
Gaceta Medica de Mexico,
141 (1),
13-21.
Artículo
422 - Ramos,M.A., Sanchez-Lopez,R., Mares,R.E., Olvera,F., Alagon,A.. Identification of an Entamoeba histolytica gene encoding a protein disulfide isomerase that functionally complements the dsbA mutation in Escherichia coli.
Molecular and Biochemical Parasitology,
143 (2),
236-240.
Artículo
423 - Sadurni,P., Alagon,A., Aliev,R., Burillo,G., Hoffman,A.S.. Immobilization of streptavidin-horseradish peroxidase onto a biotinylated poly(acrylic acid) backbone that had been radiation-grafted to a PTFE film.
Journal of Biomaterials Science-Polymer Edition,
16 (2),
181-187.
Artículo
424 - Salgado,M., Villagomez-Castro,J.C., Rocha-Rodriguez,R., Sabanero-Lopez,M., Ramos,M.A., Alagon,A., Lopez-Romero,E., Sanchez-Lopez,R.. Entamoeba histolytica: Biochemical and molecular insights into the activities within microsomal fractions.
Experimental Parasitology,
110 (4),
363-373.
Artículo
425 - Sanchez,R., Saralegui,A., Olivos-Garcia,A., Scapolla,C., Damonte,G., Sanchez-Lopez,R., Alagon,A., Stock,R.P.. Entamoeba histolytica: intracellular distribution of the sec61alpha subunit of the secretory pathway and down-regulation by antisense peptide nucleic acids.
Experimental Parasitology,
109 (4),
241-251.
Artículo
426 - Vazquez,H., Chavez-Haro,A., Garcia-Ubbelohde,W., Mancilla-Nava,R., Paniagua-Solis,J., Alagon,A., Sevcik,C.. Pharmacokinetics of a F(ab')(2) scorpion antivenom in healthy human volunteers.
Toxicon,
46 (7),
797-805.
News Item
427 - Chippaux,J.P., Stock,R.P., Alagon,A.. Report of the 2nd international conference on envenomations in Africa (Deuxieme colloque international sur les envenomations en Afrique).
Toxicon,
46 (1),
115-118.
Artículo
428 - de Roodt,A.R., Paniagua-Solis,J.F., Dolab,J.A., Estevez-Ramirez,J., Ramos-Cerrillo,B., Litwin,S., Dokmetjian,J.C., Alagon,A.. Effectiveness of two common antivenoms for North, Central, and South American Micrurus envenomations.
Journal of Toxicology - Clinical Toxicology,
42 (2),
171-178.
Artículo
429 - Ramos-Cerrillo,B., Olvera,A., Odell,G.V., Zamudio,F., Paniagua-Solis,J., Alagon,A., Stock,R.P.. Genetic and enzymatic characterization of sphingomyelinase D isoforms from the North American fiddleback spiders Loxosceles boneti and Loxosceles reclusa.
Toxicon,
44 (5),
507-514.
Divulgación
430 - Alagon,A., Odell,G.. Neutralization of Centruroides noxius envenomization of a gila monster.
Forum Magazine.American Tarantula Society,
13,
75.
Divulgación
Artículo
432 - D'Suze,G., Moncada,S., Gonzalez,C., Sevcik,C., Aguilar,V., Alagon,A.. Relationship between plasmatic levels of various cytokines, tumour necrosis factor, enzymes, glucose and venom concentration following Tityus scorpion sting.
Toxicon,
41 (3),
367-375.
Nacional
433 - Alagon,A., Possani,L.D.. Desarrollo de nuevos f rmacos a partir de la fauna tropical. Fronteras de la Biología en los Inicios del Siglo XXI, Módulo VII .
123-160,
Mexico,D.F..
Nacional
434 - Alagon,A., Carillo,C., Chavez-Haro,A., De la Mora-Zerpa,C., Larralde,C., Lamas,N, Martin,E, Osnaya-Romero,N., Perez,Y, Possani,L.D., Romero-Zamora,L.. Práctica Médica Efectiva- Alacranismo (T63.2, X22).
Mexico.
Artículo
435 - Nieto-Sotelo,J., Martinez,L.M., Ponce,G., Cassab,G.I., Alagon,A., Meeley,R.B., Ribaut,J.M., Yang,R.. Maize HSP101 Plays Important Roles in Both Induced and Basal Thermotolerance and Primary Root Growth.
Plant Cell,
14 (7),
1621-1633.
Artículo
436 - Ramos,M.A., Sanchez-Lopez,R., Olvera,F., Alagon,A.. Entamoeba histolytica genomic organization: identification, structure, and phylogenetic relationship of two serine-threonine protein kinases.
Experimental Parasitology,
100 (2),
135-139.
Artículo
437 - Sanchez,R., Alagon,A., Stock,R.P.. Entamoeba histolytica: intracellular distribution of the proteasome.
Experimental Parasitology,
102 (3-4),
187-190.
Divulgación
438 - Alagon,A.. Anticuerpos seguros y eficaces: la revoluacion de los nuevos antivenenos.
Revista Universidad de Mexico,
617.
Divulgación
Artículo
440 - Juarez,P., Sanchez-Lopez,R., Stock,R.P., Olvera,A., Ramos,M.A., Alagon,A.. Characterization of the Ehrab8 gene, a marker of the late stages of the secretory pathway of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
116 (2),
223-228.
Artículo
441 - Stock,R.P., Olvera,A., Sanchez,R., Saralegui,A., Scarfi,S., Sanchez-Lopez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Alagon,A.. Inhibition of gene expression in Entamoeba histolytica with antisense peptide nucleic acid oligomers.
Nature Biotechnology,
19 (3),
231-234.
Divulgación
442 - Ramos,M.A., Alagon,A.. Ruta secretoria y Entamoeba histolytica.
Mensaje Bioquimico,
25,
111-128.
Artículo
443 - Gutierrez,A., Sanchez-Lopez,R., Ramos,M.A., Alagon,A.. Cloning of the Entamoeba histolytica STT3 gene, a subunit of the oligosaccharyltransferase complex.
Archives of Medical Research,
31 (4 Suppl),
S162-S164.
Artículo
444 - Juarez,P., Sanchez-Lopez,R., Ramos,M.A., Stock,R.P., Alagon,A.. Rab8 as a molecular model of vesicular trafficking to investigate the latter steps of the secretory pathway in Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S157-S159.
Artículo
445 - Ramos,M.A., Alagon,A.. Molecular cloning of a gene encoding a PDI-like protein from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S173-S175.
Artículo
446 - Ramos,M.A., Sanchez-Lopez,R., Alagon,A.. Genomic organization of a 7 Kb gene cluster from Entamoeba histolytica.
Archives of Medical Research,
31 (4 Suppl),
S263-S265.
Artículo
447 - Sanchez-Lopez,R., Siminovich,B., Alagon,A.. Entamoeba histolytica codes for a protein homologue of the Sec61 alpha subunit, a component of the endoplasmic reticulum translocon.
Archives of Medical Research,
31 (4 Suppl),
S168-S170.
Artículo
448 - Sanchez-Lopez,R., Gutierrez,A., Juarez,P., Olvera,A., Olvera,F., Ramos,M.A., Sanchez,R., Saralegui,A., Stock,R.P., Alagon,A.. Molecular genetics of the secretory pathway in Entamoeba histolytica: an overview.
Archives of Medical Research,
31 (4 Suppl),
S151-S152.
Artículo
449 - Stock,R.P., Olvera,A., Scarfi,S., Sanchez,R., Ramos,M.A., Boffa,L.C., Benatti,U., Landt,O., Alagon,A.. Inhibition of neomycin phosphorotransferase expression in Entamoeba histolytica with antisense peptide nucleic acid (PNA) oligomers.
Archives of Medical Research,
31 (4 Suppl),
S271-S272.
Nacional
450 - Estrada-Galvan,B., Scheinvar,L., Alagon,A., Olalde-Parra,G.. Resultados preliminares de electroforesis en proteínas como método auxiliar en la taxonomía de Opuntia spp.
Acta Cientifica Potosina,
15 (1),
7-24.
Artículo
451 - Que,X., Kim,D., Alagon,A., Hirata,K., Shike,H., Shimizu,C., Gonzalez,A., Burns,J.C., Reed,S.L.. Pantropic retroviral vectors mediate gene transfer and expression in Entamoeba histolytica.
Molecular and Biochemical Parasitology,
99 (2),
237-245.
Artículo
452 - Sanchez-Gonzalez,M., Alagon,A., Rodriguez-Sotres,R., Lopez-Munguia,A.. Proteolytic processing of dextransucrase of Leuconostoc mesenteroides.
Fems Microbiology Letters,
181 (1),
25-30.
Artículo
453 - Sanchez-Lopez,R., Gama-Castro,S., Ramos,M.A., Merino,E., Lizardi,P.M., Alagon,A.. Cloning and expression of the Entamoeba histolytica ERD2 gene.
Molecular and Biochemical Parasitology,
92 (2),
355-359.
Artículo
454 - Vargas-Villarreal,J., Olvera-Rodriguez,A., Mata-Cardenas,B.D., Martinez-Rodriguez,H.G., Said-Fernandez,S., Alagon-Cano,A.. Isolation of an Entamoeba histolytica intracellular alkaline phospholipase A(2).
Parasitology Research,
84 (4),
310-314.
Nacional
455 - Estrada,G., Sanchez,R., Lizardi,P.M., Alagon,A.. Entamoeba histolytica y la reaccion en cadena de polimerasa por hibridazion y liberacion enzimatica (PCR-HERA). Biologia molecular en medicina.
Coleccion de textos politecnicos, series biotecnologicas.,
47-60,
Mexico DF.
Artículo; Actas Paper
456 - Olvera,A., Olvera,F., Vines,R.R., Recillas-Targa,F., Lizardi,P.M., Dhar,S., Bhattacharya,S., Petri,W.,Jr, Alagon,A.. Stable transfection of Entamoeba histolytica trophozoites by lipofection.
Archives of Medical Research,
28 . (Spec No:49-51),
49-51.
Artículo
457 - Ramos,M.A., Mercado,G.C., Salgado,L.M., Sanchez-Lopez,R., Stock,R.P., Lizardi,P.M., Alagon,A.. Entamoeba histolytica contains a gene encoding a homologue to the 54 kDa subunit of the signal recognition particle.
Molecular and Biochemical Parasitology,
88 (1-2),
225-235.
Artículo
458 - Ramos,M.A., Stock,R.P., Sanchez-Lopez,R., Olvera,F., Lizardi,P.M., Alagon,A.. The Entamoeba histolytica proteasome alpha-subunit gene.
Molecular and Biochemical Parasitology,
84 (1),
131-135.
Artículo; Actas Paper
459 - Ramos,M.A., Stock,R.P., Lizardi,P.M., Alagon,A.. The secretory pathway of Entamoeba histolytica: characterization and expression of the SRP54 gene.
Archives of Medical Research,
28 (Spec No:56-8.),
56-58.
Artículo; Actas Paper
460 - Sanchez-Lopez,R., Gama-Castro,S., Lizardi,P.M., Alagon,A.. The secretory pathway of Entamoeba histolytica: characterization and expression of the ERD2 gene.
Archives of Medical Research,
28 (Spec No:59-61.),
59-61.
Artículo
461 - Estrada,G., Colin,L., Gaytan,P., Alagon,A., Lizardi,P.M.. Sequence-specific detection of PCR-amplified DNA by restriction enzyme release of hybrids.
Molecular and cellular probes,
10 (3),
179-185.
Artículo
462 - Miranda,R., Salgado,L.M., Sanchez-Lopez,R., Alagon,A., Lizardi,P.M.. Identification and analysis of the u6 small nuclear RNA gene from Entamoeba histolytica.
Gene,
180 (1-2),
37-42.
Artículo
463 - Ortega-Pierres,G., Alagon,A., Cortes,A., Olvera,F., Olvera,A., Gonzalez,A., Lizardi,P., Berzunza-Cruz,M., Saavedra-Lira,E., Perez-Montfort,R., Velasco-Castrejon,O., Sotero-Delgado Dominguez,I., Becker,I., Hernandez,R., Martinez-Calvillo,S., Frixione,E., Ruiz,L., Santillan,M., Vega,L., Tejero,J.M., Undeen,A.H., Kretschmer,R.R., Herion,P., Saavedra,R., Yepez-Mulia,L.. [Impact of new methodologies in the study of parasites].
Gaceta Medica de Mexico,
132 (5),
475-517.
Nacional
Artículo
465 - Michel,B., Lizardi,P.M., Alagon,A., Zurita,M.. Identification and analysis of the start site of ribosomal RNA transcription of Entamoeba histolytica.
Molecular and Biochemical Parasitology,
73 (1-2),
19-30.
Artículo
466 - Noeske-Jungblut,C., Haendler,B., Donner,P., Alagon,A., Possani,L., Schleuning,W.D.. Triabin, a highly potent exosite inhibitor of thrombin.
Journal of Biological Chemistry,
270 (48),
28629-28634.
Internacional
467 - Dehesa-Davila,M., Alagon,A.C., Possani,L.D.. Clinical toxicology of scorpion stings. Handbook of clinical toxicology of animal venoms and poisons.
221-238,
New York.
Artículo
468 - Noeske-Jungblut,C., Kratzschmar,J., Haendler,B., Alagon,A., Possani,L., Verhallen,P., Donner,P., Schleuning,W.D.. An inhibitor of collagen-induced platelet aggregation from the saliva of Triatoma pallidipennis.
Journal of Biological Chemistry,
269 (7),
5050-5053.
Artículo
469 - Palmeros,B., Guereca,L., Alagon,A., Soberon-Chavez,G.. Biochemical characterization of the lipolytic activity of pseudomonas aeruginosa IGB 83.
Process Biochemistry,
29 (3),
207-212.
Artículo
470 - Cevallos,M.A., Porta,H., Alagon,A.C., Lizardi,P.M.. Sequence of the 5.8S ribosomal gene of pathogenic and non-pathogenic isolates of Entamoeba histolytica.
Nucleic Acids Research,
21 (2),
355-355.
Note
471 - Cevallos,M.A., Navarro-Duque,C., Varela-Julia,M., Alagon,A.C.. Molecular mass determination and assay of venom hyaluronidases by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
Toxicon,
30 (8),
925-930.
Note
472 - Michel,B., Alagon,A., Lizardi,P.M., Zurita,M.. Characterization of a repetitive DNA element from Entamoeba histolytica.
Molecular and Biochemical Parasitology,
51 (1),
165-168.
Artículo
473 - Possani,L.D., Fletcher,P.L., Fletcher,M.D., Rode,G.S., Mochca-Morales,J., Lucas,S., Coronas,F.V., Alagon,A.C., Martin,B.M.. Structural and functional characteristics of toxins purified from the venom of the Brazilian scorpion Tityus serrulatus Lutz and Mello.
Memorias do Instituto Butantan,
54 (2),
35-52.
Artículo
474 - Schleuning,W.D., Alagon,A., Boidol,W., Bringmann,P., Petri,T., Kratzschmar,J., Haendler,B., Langer,G., Baldus,B., Witt,W.. Plasminogen activators from the saliva of Desmodus rotundus (common vampire bat): unique fibrin specificity.
Annals of the New York Academy of Sciences,
667,
395-403.
*
Artículo
475 - Kratzschmar,J., Haendler,B., Langer,G., Boidol,W., Bringmann,P., Alagon,A., Donner,P., Schleuning,W.D.. The plasminogen activator family from the salivary gland of the vampire bat Desmodus rotundus: cloning and expression.
Gene,
105 (2),
229-237.
Note
476 - Vargas-Villarreal,J., Martin-Polo,J.J., Reynaud,E., Alagon,A.C.. A new affinity adsorbent for the purification of phospholipases A1 and A2 from animal venoms.
Toxicon,
29 (1),
119-124.
Artículo
477 - Zurita,M., Alagon,A., Vargas-Villarreal,J., Lizardi,P.M.. The Entamoeba histolytica rDNA episome: nuclear localization, DNAase I sensitivity map, and specific DNA-protein interactions.
Molecular Microbiology,
5 (8),
1843-1851.
Note
478 - Laclette,J.P., Alagon,A., Willms,K., Torre-Blanco,A.. Purification of antigen B from Taenia solium cysticerci by affinity to mammalian collagen.
Journal of Parasitology,
76 (2),
273-275.
Artículo
479 - Alagon,A.C., Guzman,H.S., Martin,B.M., Ramirez,A.N., Carbone,E., Possani,L.D.. Isolation and characterization of two toxins from the Mexican scorpion Centruroides limpidus limpidus Karsch.
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology,
89 (1),
153-161.
480 - Alagon Cano, Alejandro. Enzimas hidroliticas del veneno de heloderma horridum horridum : fosfolipasa A2 y calicreina.
Doctorado en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
Artículo
481 - Alagon,A., Possani,L.D., Smart,J., Schleuning,W.D.. Helodermatine, a kallikrein-like, hypotensive enzyme from the venom of Heloderma horridum horridum (Mexican beaded lizard).
Journal of Experimental Medicine,
164 (6),
1835-1845.
Artículo
482 - Sosa,B.P., Alagon,A.C., Martin,B.M., Possani,L.D.. Biochemical characterization of the phospholipase A2 purified from the venom of the Mexican beaded lizard (Heloderma horridum horridum Wiegmann).
Biochemistry,
25 (10),
2927-2933.
*
Artículo
483 - King,T.P., Alagon,A.C., Kuan,J., Sobotka,A.K., Lichtenstein,L.M.. Immunochemical studies of yellowjacket venom proteins.
Molecular Immunology,
20 (3),
297-308.
*
Artículo
484 - Alagon,A.C., Maldonado,M.E., Julia,J.Z., Sanchez,C.R., Possani,L.D.. Venom from two sub-species of Heloderma horridum (Mexican beaded lizard): general characterization and purification of N-benzoyl-L-arginine ethyl ester hydrolase.
Toxicon,
20 (2),
463-475.
*
Artículo
485 - King,T.P., Alagon,A., Kochoumian,L., Kuan,J., Sobotka,A., Lichtenstein,L.M.. Limited proteolysis of antigens E and K from ragweed pollen.
Archives of Biochemistry and Biophysics,
212 (1),
127-135.
*
Artículo
486 - Possani,L., Steinmetz,W.E., Dent,M.A., Alagon,A.C., Wuthrich,K.. Preliminary spectroscopic characterization of six toxins from Latin American scorpions.
Biochimica et Biophysica Acta (BBA) - Protein Structure,
669 (2),
183-192.
*
Artículo
487 - Alagon,A.C., Molinar,R.R., Possani,L.D., Fletcher,P.L., Cronan,J.E., Julia,J.Z.. Venom from the snake Bothrops asper Garman. Purification and characterization of three phospholipases A2.
Biochemical Journal,
185 (3),
695-704.
*
Artículo
488 - Alagon,A.C., King,T.P.. Activation of polysaccharides with 2-iminothiolane and its uses.
Biochemistry,
19 (18),
4341-4345.
*
Note
489 - Possani,L.D., Sosa,B.P., Alagon,A.C., Burchfield,P.M.. The venom from the snakes Agkistrodon bilineatus Taylori and Crotalus durissus Totonacus: lethality, biochemical and immunological properties.
Toxicon,
18 (3),
356-360.
*
Artículo
490 - Possani,L.D., Fletcher,P.L., Alagon,A.B., Alagon,A.C., Julia,J.Z.. Purification and characterization of a mammalian toxin from venom of the Mexican scorpion, Centruroides limpidus tecomanus Hoffmann.
Toxicon,
18 (2),
175-183.
*
491 - Alagon Cano, Alejandro. Estudio sobre los venenos de varias especies zoologicas.
Instituto de Investigacions Biomedicas,
Maestria en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Possani Postay, Lourival D.
Artículo
492 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Varela,M.J., Julia,J.Z.. Purification and characterization of a phospholipase A2 from the venom of the coral snake, Micrurus fulvius microgalbineus (Brown and Smith).
Biochemical Journal,
179 (3),
603-606.
*
Artículo
493 - Sosa,B.P., Alagon,A.C., Possani,L.D., Julia,J.Z.. Comparison of phospholipase activity with direct and indirect lytic effects of animal venoms upon human red cells.
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry,
64 (2),
231-234.
*
Nacional
494 - Arauco,R., Alagon,A.. [Propanolol in arterial hypertension. Beta-blockaders. Recent advances].
Prensa médica mexicana,
44 (5-6),
97-104.
*
Artículo
495 - King,T.P., Sobotka,A.K., Alagon,A., Kochoumian,L., Lichtenstein,L.M.. Protein allergens of white-faced hornet, yellow hornet, and yellow jacket venoms.
Biochemistry,
17 (24),
5165-5174.
*
Artículo
496 - Possani,L.D., Alagon,A.C., Fletcher,P.L., Erickson,B.W.. Purification and properties of mammalian toxins from the venom of Brazilian Scorpion Tityus serrulatus Lutz and Mello.
Archives of Biochemistry and Biophysics,
180 (2),
394-403.
*
Artículo
497 - Frenk,J., Acuna,D.L., Bobadilla,J.L., Alagon,A.. [Liberal medicine and institutional medicine in Mexico].
Salud Publica de Mexico,
18 (3),
481-493.
*
- Teléfonos
-
Oficina +52 (777) 329-1649
desde la CDMX 562-27649
Red UNAM 27649 -
Laboratorio +52 (777) 329-1602
desde la CDMX 562-27602
Red UNAM 27602