Dra. Georgina Gurrola Briones
Investigadora Titular A Tiempo Completo
Biología Molecular y Bioquímica de venenos de animales ponzoñosos
Nivel C del PRIDE
Doctorado, en Investigacion Biomedica Basica, IBt-UNAM (1995)
Maestría, Bioquímica, Fac. de Química-UNAM (1986)
Licenciatura, Químico Farmaceutico Biologo, FES-Cuautitlan-UNAM (1979)
- Activos
- Graduados
-
Maestría
-
Síntesis de péptidos sin puentes disulfuro derivados del transcriptoma de la glándula venenosa del alacrán Superstitionia donensis: evaluación de su actividad antimicrobiana
-
Licenciatura
1 - Miranda Espino, Rodolfo (2025). Sintesis de peptidos sin puentes disulfuro derivados del transcriptoma de la glandula venenosa del alacran superstitionia donensis: evaluacion de su actividad antimicrobiana.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Gurrola Briones, Georgina
2 - Vázquez Ramírez, José Noé (2021). Caracterización bioquímica de los componentes del veneno del alacrán Centruroides nigrescens.
Escuela de Estudios Superiores del Jicarero, Jojutla,
Licenciatura en Biología,
Universidad Autónoma del Estado de Morelos.
*
Asesor: Gurrola Briones, Georgina
3 - Garcia Guerrero, Ivan Alberto (2018). Caracterizacion bioquimica del veneno del alacran Centruroides ornatus, una especie de interes medico .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Gurrola Briones, Georgina
4 - Uribe Mendonza, Ivett (2015). Estudio de la interacción de la Imperatoxina A con el receptor de la Ryanodina por medio de ensayos de entrecruzamiento.
Facultad de Ciencias Biológicas ,
Bióloga,
Universidad Autónoma del Estado de Morelos.
*
Asesor: Gurrola Briones, Georgina
5 - Sanchez Vasquez, Lorenzo (2011). Diseno de nuevos peptidos : sinteticos antimicrobianos.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Gurrola Briones, Georgina
6 - Gomez Utrera, Dora Luz (2010). Identificacion de eventos moleculares asociados a la intoxicacion con la toxina Cn2 mediante electroforesis bidimensional .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Gurrola Briones, Georgina
7 - Cazares Ordonez, Verna (2009). Busqueda y evaluacion de un marcador molecular para el estudio de los canales de potasio tipo hERG3 a partir del veneno del alacran Centruroides gracilis .
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Gurrola Briones, Georgina
8 - Hernández Aponte,Cynthia Annabel (2009). Búsqueda, identificación y caracterización de componentes de venenos de alacranes Mexicanos con actividad antibacteriana.
Centro de Investigación en Biotecnología ,
Maestro en Biotecnología,
Universidad Autónoma del Estado de Morelos.
*
Asesor: Gurrola-Briones, Georgina
9 - Hernández Aponte,Cynthia Annabel (2007). Caracterización bioquímica de componentes de bajo peso molecular del veneno del alacrán Centruroides noxius Hoffmann.
Facultad de Ciencias Químicas e Ingeniería,
Ingeniero Químico,
Universidad Autónoma del Estado de Morelos.
*
Asesor: Gurrola Briones, Georgina
10 - Espino Solis, Gerardo Pavel (2004). Desarrollo de un peptido sintetico capaz de inducir anticuerpos neutralizantes en contra del veneno del alacran Centruroides noxius Hoffmann.
Instituto de Biotecnologia,
Maestro en Ciencias (Bioquimica),
UNAM.
Asesor: Gurrola Briones, Georgina
11 - Chavira Suarez, Erika (2004). Estudio del uso de una vacuna de DNA, como un posible tratamiento en contra del envenenamiento por picadura de alacran.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
Asesor: Gurrola Briones, Georgina
12 - Pimienta Rosales, Genaro (2000). Aislamiento y caracterizacion de un peptido del veneno del alacran Centruroides noxiushoffmann, que bloquea especificamente el canal de potasio Herg.
Instituto de Biotecnologia,
Maestro en Ciencias (Bioquimica),
UNAM.
Asesor: Gurrola Briones, Georgina
Total de publicaciones: 71
- Tipo
- Fecha
Artículo
13 - Haji-Ghassemi,O., Chen,Y.S., Woll,K., Gurrola,G.B., Valdivia,C.R., Cai,W., Li,S., Valdivia,H.H., Van Petegem,F. (2023). Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Science Advances,
9 (21),
eadf4936.
Artículo
14 - Naseem,M.U., Gurrola-Briones,G., Romero-Imbachi,M.R., Borrego,J., Carcamo-Noriega,E., Beltran-Vidal,J., Zamudio,F.Z., Shakeel,K., Possani,L.D., Panyi,G. (2023). Characterization and Chemical Synthesis of Cm39 (a-KTx 4.8): A Scorpion Toxin That Inhibits Voltage-Gated K(+) Channel K(V)1.2 and Small- and Intermediate-Conductance Ca(2+)-Activated K(+) Channels K(Ca)2.2 and K(Ca)3.1.
Toxins (Basel),
15 (1),
41.
Artículo
15 - Csoti,A., Najera-Meza,R.C., Bogar,F., Tajti,G., Szanto,T.G., Varga,Z., Gurrola,G.B., Toth,G.K., Possani,L.D., Panyi,G. (2022). sVmKTx, a transcriptome analysis-based synthetic peptide analogue of Vm24, inhibits Kv1.3 channels of human T cells with improved selectivity.
Biochemical Pharmacology,
199,
115023.
Artículo
16 - Garcia-Guerrero,I.A., Carcamo-Noriega,E., Gomez-Lagunas,F., Gonzalez-Santillan,E., Zamudio,F.Z., Gurrola,G.B., Possani,L.D. (2020). Biochemical characterization of the venom from the Mexican scorpion Centruroides ornatus, a dangerous species to humans.
Toxicon,
173,
27-38.
Artículo
17 - Gurrola, G. B., Guijarro, J. I., Delepierre, M., Mendoza, R. L. L., Cid-Uribe, J. I., Coronas, F. V., Possani, L. D. (2019). Cn29, a novel orphan peptide found in the venom of the scorpion Centruroides noxius: Structure and function.
Toxicon,
167,
184-191.
Artículo
Artículo
19 - Xiao,L., Gurrola,G.B., Zhang,J., Valdivia,C.R., SanMartin,M., Zamudio,F.Z., Zhang,L., Possani,L.D., Valdivia,H.H. (2016). Structure-function relationships of peptides forming the calcin family of ryanodine receptor ligands.
Journal of General Physiology,
147 (5),
375-394.
Revisión
20 - Ortiz,E., Gurrola,G.B., Schwartz,E.F., Possani,L.D. (2015). Scorpion venom components as potential candidates for drug development.
Toxicon,
93,
125-135.
Artículo
21 - Zhao,Y.T., Valdivia,C.R., Gurrola,G.B., Powers,P.P., Willis,B.C., Moss,R.L., Jalife,J., Valdivia,H.H. (2015). Arrhythmogenesis in a catecholaminergic polymorphic ventricular tachycardia mutation that depresses ryanodine receptor function.
Proceedings of the National Academy of Sciences of the United States of America,
112 (13),
E1669-E1677.
Revisión
22 - Zhao,Y.T., Valdivia,C.R., Gurrola,G.B., Hernandez,J.J., Valdivia,H.H. (2015). Arrhythmogenic mechanisms in ryanodine receptor channelopathies.
Science China Life Sciences,
58 (1),
54-58.
Revisión
23 - Quintero-Hernandez,V., Jimenez-Vargas,J.M., Gurrola,G.B., Valdivia,H.H., Possani,L.D. (2013). Scorpion venom components that affect ion-channels function.
Toxicon,
76,
328-342.
Artículo
24 - Riano-Umbarila,L., Olamendi-Portugal,T., Morelos-Juarez,C., Gurrola,G.B., Possani,L.D., Becerril,B. (2013). A novel human recombinant antibody fragment capable of neutralizing Mexican scorpion toxins.
Toxicon,
76,
370-376.
Artículo
25 - Sanchez-Vasquez,L., Silva-Sanchez,J., Jimenez-Vargas,J.M., Rodriguez-Romero,A., Munoz-Garay,C., Rodriguez,M.C., Gurrola,G.B., Possani,L.D. (2013). Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin.
Biochimica et Biophysica Acta (BBA) - General Subjects,
1830 (6),
3427-3436.
Artículo
26 - Gurrola,G.B., Hernandez-Lopez,R.A., Rodriguez de la Vega,R.C., Varga,Z., Batista,C.V., Salas-Castillo,S.P., Panyi,G., del Rio-Portilla,F., Possani,L.D. (2012). Structure, function and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes.
Biochemistry,
51 (19),
4049-4061.
Artículo
27 - Schiavon,E., Pedraza-Escalona,M., Gurrola,G.B., Olamendi-Portugal,T., Corzo,G., Wanke,E., Possani,L.D. (2012). Negative-shift activation, current reduction and resurgent currents induced by beta-toxins from Centruroides scorpions in sodium channels.
Toxicon,
59 (2),
283-293.
Artículo
28 - Varga,Z., Gurrola-Briones,G., Papp,F., Rodriguez de la Vega,R.C., Pedraza-Alva,G., Tajhya,R.B., Gaspar,R., Cardenas,L., Rosenstein,Y., Beeton,C., Possani,L.D., Panyi,G. (2012). Vm24, a Natural Immunosuppressant Peptide Potently and Selectively Blocks Kv1.3 Potassium Channels of Human T Cells.
Molecular Pharmacology,
82 (3),
372-382.
Artículo
29 - Hernandez-Aponte,C.A., Silva-Sanchez,J., Quintero-Hernandez,V., Rodriguez-Romero,A., Balderas,C., Possani,L.D., Gurrola,G.B. (2011). Vejovine, a new antibiotic from the scorpion venom of Vaejovis mexicanus.
Toxicon,
57 (1),
84-92.
Artículo; Actas Paper
30 - Jimenez-Vargas,J.M., Restano-Cassulini,R., Quintero-Hernandez,V., Gurrola,G.B., Possani,L.D. (2011). Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function.
Peptides,
32 (3),
560-567.
Artículo
31 - Gurrola,G.B., Capes,E.M., Zamudio,F.Z., Possani,L.D., Valdivia,H.H. (2010). Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca-Release Channels/Ryanodine Receptors.
Pharmaceuticals.(Basel),
3 (4),
1093-1107.
Revisión
32 - Prestipino,G., Corzo,G., Romeo,S., Murgia,A.R., Zanardi,I., Gurrola,G., Possani,L.D. (2009). Scorpion toxins that block transient currents (IA) of rat cerebellum granular cells.
Toxicology Letters,
187 (1),
1-9.
Artículo
33 - Aparicio-Fabre,R., Guillen,G., Estrada,G., Olivares-Grajales,J., Gurrola,G., Sanchez,F. (2006). Profilin tyrosine phosphorylation in poly-l-proline-binding regions inhibits binding to phosphoinositide 3-kinase in Phaseolus vulgaris.
Plant Journal,
47 (4),
491-500.
Artículo; Actas Paper
34 - Restano-Cassulini,R., Korolkova,Y.V., Diochot,S., Gurrola,G., Guasti,L., Possani,L., Lazdunski,M., Grishin,E., Arcangeli,A., Wanke,E. (2006). Species Diversity and Peptide Toxins Blocking Selectivity of ERG Subfamily K+ Channels in CNS.
Molecular Pharmacology,
69 (5),
1673-1683.
Artículo
35 - Schiavon,E., Sacco,T., Restano-Cassulini,R., Gurrola,G., Tempia,F., Possani,L.D., Wanke,E. (2006). Resurgent current and voltage sensor-trapping enhanced activation by a {beta}-scorpion toxin solely in nav1.6 channel: Significance in Mice Purkinje Neurons.
Journal of Biological Chemistry,
281 (29),
20326-20337.
Artículo
36 - Coronas,F.I., Balderas,C., Lopez,L.P., Possani,L.D., Gurrola,G.B. (2005). Amino acid sequence determination and chemical synthesis of CllErg1 (gamma-KTx1.5), a K+ channel blocker peptide isolated from the scorpion Centruroides limpidus limpidus.
Journal of the Brazilian Chemical Society,
16 (3A),
404-411.
Artículo
37 - Frenal,K., Xu,C.Q., Wolff,N., Wecker,K., Gurrola,G.B., Zhu,S.Y., Chi,C.W., Possani,L.D., Tytgat,J., Delepierre,M. (2004). Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K(+) channels.
Proteins,
56 (2),
367-375.
Artículo
38 - Rosales-Castillo,J.A., Acosta-Saavedra,L.C., Torres,R., Ochoa-Fierro,J., Borja-Aburto,V.H., Lopez-Carrillo,L., Garcia-Vargas,G.G., Gurrola,G.B., Cebrian,M.E., Calderon-Aranda,E.S. (2004). Arsenic exposure and human papillomavirus response in non-melanoma skin cancer Mexican patients: a pilot study.
International Archives of Occupational and Environmental Health,
77 (6),
418-423.
Artículo
39 - Gazarian,T.G., Selisko,B., Gurrola,G.B., Possani,L.D., Gazarian,K.G. (2003). Potential of Peptides Selected from Random Phage-Displayed Libraries to Mimic Conformational Epitopes: A Study on Scorpion Toxin Cn2 and the Neutralizing Monoclonal Antibody BCF2.
Combinatorial Chemistry & High Throughput Screening,
6 (2),
119-132.
Artículo
40 - Corona,M., Gurrola,G.B., Merino,E., Cassulini,R.R., Valdez-Cruz,N.A., Garcia,B, Ramirez-Dominguez,M.E., Coronas,F.I., Zamudio,F.Z., Wanke,E., Possani,L.D. (2002). A large number of novel Ergtoxin-like genes and ERG K(+)-channels blocking peptides from scorpions of the genus Centruroides.
FEBS Letters,
532 (1-2),
121-126.
Artículo
41 - Lecchi,M., Redaelli,E., Rosati,B., Gurrola,G., Florio,T., Crociani,O., Curia,G., Cassulini,R.R., Masi,A., Arcangeli,A., Olivotto,M., Schettini,G., Possani,L.D., Wanke,E. (2002). Isolation of a long-lasting eag-related gene-type K+ current in MMQ lactotrophs and its accommodating role during slow firing and prolactin release.
Journal of Neuroscience,
22 (9),
3414-3425.
Artículo
42 - Pardo-Lopez,L., Garcia-Valdes,J., Gurrola,G.B., Robertson,G.A., Possani,L.D. (2002). Mapping the receptor site for ergtoxin, a specific blocker of ERG channels.
FEBS Letters,
510 (1-2),
45-49.
Artículo
43 - Frau,A., Pisciotta,M., Gurrola,G.B., Possani,L.D., Prestipino,G. (2001). Synthetic undecapeptide (NTX10-20) of noxiustoxin blocks completely the I(A) potassium currents of cerebellum granular cells.
European Biophysics Journal,
29 (8),
569-573.
Artículo
44 - Rocchetti,M., Besana,A., Gurrola,G.B., Possani,L.D., Zaza,A. (2001). Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential.
Journal of Physiology,
534 (Pt 3),
721-732.
Carta
45 - Bottiglieri,C., Ferrara,L., Corona,M., Gurrola,G.B., Batista,C., Wanke,E., Possani,L.D. (2000). Disulfide bridges of ergtoxin, a member of a new sub-family of peptide blockers of the ether-a-go-go-related K+ channel.
FEBS Letters,
479 (3),
156-157 .
Artículo
46 - Torres-Larios,A., Gurrola,G.B., Zamudio,F.Z., Possani,L.D. (2000). Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus.
European Journal of Biochemistry,
267 (16),
5023-5031.
Artículo
47 - Calderon-Aranda,E.S., Selisko,B., York,E.J., Gurrola,G.B., Stewart,J.M., Possani,L.D. (1999). Mapping of an epitope recognized by a neutralizing monoclonal antibody specific to toxin Cn2 from the scorpion Centruroides noxius, using discontinuous synthetic peptides.
European Journal of Biochemistry,
264 (3),
746-755.
Artículo
48 - Gurrola,G.B., Rosati,B., Rocchetti,M., Pimienta,G., Zaza,A., Arcangeli,A., Olivotto,M., Possani,L.D., Wanke,E. (1999). A toxin to nervous, cardiac, and endocrine ERG K+ channels isolated from Centruroides noxius scorpion venom.
FASEB Journal,
13 (8),
953-962.
Artículo
49 - Gurrola,G.B., Arevalo,C., Sreekumar,R., Lokuta,A.J., Walker,J.W., Valdivia,H.H. (1999). Activation of ryanodine receptors by imperatoxin A and a peptide segment of the II-III loop of the dihydropyridine receptor.
Journal of Biological Chemistry,
274 (12),
7879-7886.
*
Revisión
50 - Possani,L.D., Selisko,B., Gurrola,G.B. (1999). Structure and function of scorpion toxins affecting K+-channels.
Perspectives In Drug Discovery And Design,
16,
15-40.
Artículo
51 - Samso,M., Trujillo,R., Gurrola,G.B., Valdivia,H.H., Wagenknecht,T. (1999). Three-dimensional location of the imperatoxin A binding site on the ryanodine receptor.
Journal of Cell Biology,
146 (2),
493-499.
*
Artículo
52 - Zhu,X., Gurrola,G., Jiang,M.T., Walker,J.W., Valdivia,H.H. (1999). Conversion of an inactive cardiac dihydropyridine receptor II-III loop segment into forms that activate skeletal ryanodine receptors.
FEBS Letters,
450 (3),
221-226.
*
Artículo
53 - Martinez,F., Munoz-Garay,C., Gurrola,G., Darszon,A., Possani,L.D., Becerril,B. (1998). Site directed mutants of Noxiustoxin reveal specific interactions with potassium channels.
FEBS Letters,
429 (3),
381-384.
Artículo
Artículo
55 - Zamudio,F.Z., Gurrola,G.B., Arevalo,C., Sreekumar,R., Walker,J.W., Valdivia,H.H., Possani,L.D. (1997). Primary structure and synthesis of Imperatoxin A (IpTx(a)), a peptide activator of Ca2+ release channels/ryanodine receptors.
FEBS Letters,
405 (3),
385-389.
Artículo
56 - Dehesa-Davila,M., Ramirez,A.N., Zamudio,F.Z., Gurrola-Briones,G., Lievano,A., Darszon,A., Possani,L.D. (1996). Structural and functional comparison of toxins from the venom of the scorpions Centruroides infamatus infamatus, Centruroides limpidus limpidus and Centruroides noxius.
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology,
113 (2),
331-339.
Artículo
57 - Martinez,F., Becerril,B., Gurrola,G.B., Martin,B.M., Possani,L.D. (1996). Synthesis and expression of the gene coding for noxiustoxin, a K+ channel-blocking peptide from the venom of the scorpion Centruroides noxius.
Toxicon,
34 (11-12),
1413-1419.
Artículo
58 - Nieto,A.R., Gurrola,G.B., Vaca,L., Possani,L.D. (1996). Noxiustoxin 2, a novel K+ channel blocking peptide from the venom of the scorpion Centruroides noxius Hoffmann.
Toxicon,
34 (8),
913-922.
Artículo
59 - Olamendi-Portugal,T., Gomez-Lagunas,F., Gurrola,G.B., Possani,L.D. (1996). A novel structural class of K+-channel blocking toxin from the scorpion Pandinus imperator.
Biochemical Journal,
315 (Pt 3),
977-981.
Artículo
60 - Dauplais,M., Gilquin,B., Possani,L.D., Gurrola-Briones,G., Roumestand,C., Menez,A. (1995). Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins.
Biochemistry,
34 (51),
16563-16573.
Artículo
61 - Drakopoulou,E., Cotton,J., Virelizier,H., Bernardi,E., Schoofs,A.R., Partiseti,M., Choquet,D., Gurrola,G., Possani,L.D., Vita,C. (1995). Chemical synthesis, structural and functional characterisation of noxiustoxin, a powerful blocker of lymphocyte voltage-dependent K+ channels.
Biochemical and Biophysical Research Communications,
213 (3),
901-907.
Artículo
62 - Gurrola,G.B., Possani,L.D. (1995). Structural and functional features of noxiustoxin: a K+ channel blocker.
Biochemistry and Molecular Biology International,
37 (3),
527-535.
Artículo
63 - Herion,P., Gurrola-Briones,G., Sanchez,M.D.R., Saavedra,R., Possani,L.D. (1995). Monoclonal antibodies against noxiustoxin.
Hybridoma,
14 (3),
247-251.
Artículo
64 - Gurrola,G.B., Moreno-Hagelsieb,G., Zamudio,F.Z., Garcia,M., Soberon,X., Possani,L.D. (1994). The disulfide bridges of toxin 2 from the scorpion Centruroides noxius Hoffmann and its three-dimensional structure calculated using the coordinates of variant 3 from Centruroides sculpturatus.
FEBS Letters,
347 (1),
59-62.
Artículo
65 - Martin,B.M., Ramirez,A.N., Gurrola,G.B., Nobile,M., Prestipino,G., Possani,L.D. (1994). Novel K(+)-channel-blocking toxins from the venom of the scorpion Centruroides limpidus limpidus Karsch.
Biochemical Journal,
304 (Pt 1),
51-56.
Artículo
66 - Ramirez,A.N., Martin,B.M., Gurrola,G.B., Possani,L.D. (1994). Isolation and characterization of a novel toxin from the venom of the scorpion Centruroides limpidus limpidus Karsch.
Toxicon,
32 (4),
479-490.
Artículo
67 - Vaca,L., Gurrola,G.B., Possani,L.D., Kunze,D.L. (1993). Blockade of a KCa channel with synthetic peptides from noxiustoxin: a K+ channel blocker.
Journal of Membrane Biology,
134 (2),
123-129.
Artículo
68 - Possani,L.D., Martin,B.M., Yatani,A., Mochca-Morales,J., Zamudio,F.Z., Gurrola,G.B., Brown,A.M. (1992). Isolation and physiological characterization of taicatoxin, a complex toxin with specific effects on calcium channels.
Toxicon,
30 (11),
1343-1364.
Artículo
69 - Zamudio,F., Saavedra,R., Martin,B.M., Gurrola-Briones,G., Herion,P., Possani,L.D. (1992). Amino acid sequence and immunological characterization with monoclonal antibodies of two toxins from the venom of the scorpion Centruroides noxius Hoffmann.
European Journal of Biochemistry,
204 (1),
281-292.
Artículo
70 - Gurrola,G.B., Molinar-Rode,R., Sitges,M., Bayon,A., Possani,L.D. (1989). Synthetic peptides corresponding to the sequence of noxiustoxin indicate that the active site of this K+ channel blocker is located on its amino-terminal portion.
Journal of Neural Transmission,
77 (1),
11-20.
Artículo
71 - Martin,B.M., Carbone,E., Yatani,A., Brown,A.M., Ramirez,A.N., Gurrola,G.B., Possani,L.D. (1988). Amino acid sequence and physiological characterization of toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann.
Toxicon,
26 (9),
785-794.
Artículo
72 - Ramirez,A.N., Gurrola,G.B., Martin,B.M., Possani,L.D. (1988). Isolation of several toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann.
Toxicon,
26 (9),
773-783.
Artículo
73 - Brown,A.M., Yatani,A., Lacerda,A.E., Gurrola,G.B., Possani,L.D. (1987). Neurotoxins that act selectively on voltage-dependent cardiac calcium channels.
Circulation Research,
61 (4 Pt 2),
I6-I9.
Internacional
74 - Possani,L.D., Gurrola,G.B., Schwartz,E., Restano,R. (2011). Bioquimica y biologia molecular de los venenos de escorpiones de importancia medica en el continente americano. Emergencias por Animales Ponzonosos en las Americas .
147-180,
Mexico.
Internacional
75 - Gurrola,G.B., Zhu,X., Valdivia,H (2005). Scorpion Peptides as High-Affinity Probes of Ryanodine Receptor Function. Ryanodine receptors : structure, function and dysfunction in clinical disease.
Developments in Cardiovascular Medicine,
191-200,
254,
New York.
Memoria in extenso
76 - Gutierrez,M.C., Estrada,G.I., Estrada-Parra,S., Gurrola,G.B., Possani,L.D. (1991). Synthetic peptides as skin test reagents in leprosy. Proceedings Leprosy Research in Latin America.
7 p,
Caracas.
Memoria in extenso
77 - Possani,L.D., Gurrola,G.B., Portugal,T.O., Zamudio,F.Z., Vaca,L.D., Calderon,S.A., Kirsch,G.E. (1991). Scorpion toxins: a model for peptide synthesis of new drugs. Proceedings First Brazilian Congress on Proteins.
352-367,
Brasil.
Nacional
78 - Gurrola,G.B., Molina-Rode,R., Zentella,A.D., Possani,L.D. (1984). Sintesis de peptidos y su posible utilizacion como vacuna contra toxinas de alacran. Avances en el mecanismo de accion de farmacos.
35-50.
Nacional divulgación
79 - Restano-Cassulini,R., Delgado-Prudencio,G., Gurrola-Briones,G. (2024). El veneno de alacrán: una mina de moléculas con potencial farmacológico.
Hypatia,
73,
32-33.
Preprint
80 - Sheard,T.M.D., Howlett,L., Kirton,H., Yang,Z., Gurrola,G., Steele,D., Jayasinghe,I., Valdivia,H.H., Colyer,J. (2020). Peptide ligands of the cardiac ryanodine receptor as super-resolution imaging probes.
bioRxiv,
Preprint posted June 28.
81 - Gurrola Briones, Georgina (1994). Caracterizacion funcional estructural de la noxiustoxina.
Instituto de Biotecnologia,
Doctorado en Investigacion Biomedica Basica,
UNAM.
Asesor: Possani, Lourival Domingos
82 - Gurrola Briones, Georgina (1986). Sintesis quimica de peptidos correspondientes a secuencias de aminoacidos de toxinas de alacran y sus propiedades.
Instituto de Biotecnologia,
Maestro en Ciencias Quimicas (Bioquimica),
UNAM.
Asesor: Possani, Lourival Domingos
83 - Gurrola Briones, Georgina (1981). Busqueda e identificacion de anticuerpos contra antigenos del sistema hla .
FES Cuautitlan,
Quimico Farmaceutico Biologo,
UNAM.
*
Asesor: Teran Ortiz, Luis Angel
Nacional divulgación
Artículo
85 - Haji-Ghassemi,O., Chen,Y.S., Woll,K., Gurrola,G.B., Valdivia,C.R., Cai,W., Li,S., Valdivia,H.H., Van Petegem,F.. Cryo-EM analysis of scorpion toxin binding to Ryanodine Receptors reveals subconductance that is abolished by PKA phosphorylation.
Science Advances,
9 (21),
eadf4936.
Artículo
86 - Naseem,M.U., Gurrola-Briones,G., Romero-Imbachi,M.R., Borrego,J., Carcamo-Noriega,E., Beltran-Vidal,J., Zamudio,F.Z., Shakeel,K., Possani,L.D., Panyi,G.. Characterization and Chemical Synthesis of Cm39 (a-KTx 4.8): A Scorpion Toxin That Inhibits Voltage-Gated K(+) Channel K(V)1.2 and Small- and Intermediate-Conductance Ca(2+)-Activated K(+) Channels K(Ca)2.2 and K(Ca)3.1.
Toxins (Basel),
15 (1),
41.
Artículo
87 - Csoti,A., Najera-Meza,R.C., Bogar,F., Tajti,G., Szanto,T.G., Varga,Z., Gurrola,G.B., Toth,G.K., Possani,L.D., Panyi,G.. sVmKTx, a transcriptome analysis-based synthetic peptide analogue of Vm24, inhibits Kv1.3 channels of human T cells with improved selectivity.
Biochemical Pharmacology,
199,
115023.
Artículo
88 - Garcia-Guerrero,I.A., Carcamo-Noriega,E., Gomez-Lagunas,F., Gonzalez-Santillan,E., Zamudio,F.Z., Gurrola,G.B., Possani,L.D.. Biochemical characterization of the venom from the Mexican scorpion Centruroides ornatus, a dangerous species to humans.
Toxicon,
173,
27-38.
Preprint
89 - Sheard,T.M.D., Howlett,L., Kirton,H., Yang,Z., Gurrola,G., Steele,D., Jayasinghe,I., Valdivia,H.H., Colyer,J.. Peptide ligands of the cardiac ryanodine receptor as super-resolution imaging probes.
bioRxiv,
Preprint posted June 28.
Artículo
90 - Gurrola, G. B., Guijarro, J. I., Delepierre, M., Mendoza, R. L. L., Cid-Uribe, J. I., Coronas, F. V., Possani, L. D.. Cn29, a novel orphan peptide found in the venom of the scorpion Centruroides noxius: Structure and function.
Toxicon,
167,
184-191.
Artículo
92 - Xiao,L., Gurrola,G.B., Zhang,J., Valdivia,C.R., SanMartin,M., Zamudio,F.Z., Zhang,L., Possani,L.D., Valdivia,H.H.. Structure-function relationships of peptides forming the calcin family of ryanodine receptor ligands.
Journal of General Physiology,
147 (5),
375-394.
Revisión
93 - Ortiz,E., Gurrola,G.B., Schwartz,E.F., Possani,L.D.. Scorpion venom components as potential candidates for drug development.
Toxicon,
93,
125-135.
Artículo
94 - Zhao,Y.T., Valdivia,C.R., Gurrola,G.B., Powers,P.P., Willis,B.C., Moss,R.L., Jalife,J., Valdivia,H.H.. Arrhythmogenesis in a catecholaminergic polymorphic ventricular tachycardia mutation that depresses ryanodine receptor function.
Proceedings of the National Academy of Sciences of the United States of America,
112 (13),
E1669-E1677.
Revisión
95 - Zhao,Y.T., Valdivia,C.R., Gurrola,G.B., Hernandez,J.J., Valdivia,H.H.. Arrhythmogenic mechanisms in ryanodine receptor channelopathies.
Science China Life Sciences,
58 (1),
54-58.
Revisión
96 - Quintero-Hernandez,V., Jimenez-Vargas,J.M., Gurrola,G.B., Valdivia,H.H., Possani,L.D.. Scorpion venom components that affect ion-channels function.
Toxicon,
76,
328-342.
Artículo
97 - Riano-Umbarila,L., Olamendi-Portugal,T., Morelos-Juarez,C., Gurrola,G.B., Possani,L.D., Becerril,B.. A novel human recombinant antibody fragment capable of neutralizing Mexican scorpion toxins.
Toxicon,
76,
370-376.
Artículo
98 - Sanchez-Vasquez,L., Silva-Sanchez,J., Jimenez-Vargas,J.M., Rodriguez-Romero,A., Munoz-Garay,C., Rodriguez,M.C., Gurrola,G.B., Possani,L.D.. Enhanced antimicrobial activity of novel synthetic peptides derived from vejovine and hadrurin.
Biochimica et Biophysica Acta (BBA) - General Subjects,
1830 (6),
3427-3436.
Artículo
99 - Gurrola,G.B., Hernandez-Lopez,R.A., Rodriguez de la Vega,R.C., Varga,Z., Batista,C.V., Salas-Castillo,S.P., Panyi,G., del Rio-Portilla,F., Possani,L.D.. Structure, function and chemical synthesis of Vaejovis mexicanus peptide 24: a novel potent blocker of Kv1.3 potassium channels of human T lymphocytes.
Biochemistry,
51 (19),
4049-4061.
Artículo
100 - Schiavon,E., Pedraza-Escalona,M., Gurrola,G.B., Olamendi-Portugal,T., Corzo,G., Wanke,E., Possani,L.D.. Negative-shift activation, current reduction and resurgent currents induced by beta-toxins from Centruroides scorpions in sodium channels.
Toxicon,
59 (2),
283-293.
Artículo
101 - Varga,Z., Gurrola-Briones,G., Papp,F., Rodriguez de la Vega,R.C., Pedraza-Alva,G., Tajhya,R.B., Gaspar,R., Cardenas,L., Rosenstein,Y., Beeton,C., Possani,L.D., Panyi,G.. Vm24, a Natural Immunosuppressant Peptide Potently and Selectively Blocks Kv1.3 Potassium Channels of Human T Cells.
Molecular Pharmacology,
82 (3),
372-382.
Artículo
102 - Hernandez-Aponte,C.A., Silva-Sanchez,J., Quintero-Hernandez,V., Rodriguez-Romero,A., Balderas,C., Possani,L.D., Gurrola,G.B.. Vejovine, a new antibiotic from the scorpion venom of Vaejovis mexicanus.
Toxicon,
57 (1),
84-92.
Artículo; Actas Paper
103 - Jimenez-Vargas,J.M., Restano-Cassulini,R., Quintero-Hernandez,V., Gurrola,G.B., Possani,L.D.. Recombinant expression of the toxic peptide ErgTx1 and role of Met35 on its stability and function.
Peptides,
32 (3),
560-567.
Internacional
104 - Possani,L.D., Gurrola,G.B., Schwartz,E., Restano,R.. Bioquimica y biologia molecular de los venenos de escorpiones de importancia medica en el continente americano. Emergencias por Animales Ponzonosos en las Americas .
147-180,
Mexico.
Artículo
105 - Gurrola,G.B., Capes,E.M., Zamudio,F.Z., Possani,L.D., Valdivia,H.H.. Imperatoxin A, a Cell-Penetrating Peptide from Scorpion Venom, as a Probe of Ca-Release Channels/Ryanodine Receptors.
Pharmaceuticals.(Basel),
3 (4),
1093-1107.
Revisión
106 - Prestipino,G., Corzo,G., Romeo,S., Murgia,A.R., Zanardi,I., Gurrola,G., Possani,L.D.. Scorpion toxins that block transient currents (IA) of rat cerebellum granular cells.
Toxicology Letters,
187 (1),
1-9.
Artículo
107 - Aparicio-Fabre,R., Guillen,G., Estrada,G., Olivares-Grajales,J., Gurrola,G., Sanchez,F.. Profilin tyrosine phosphorylation in poly-l-proline-binding regions inhibits binding to phosphoinositide 3-kinase in Phaseolus vulgaris.
Plant Journal,
47 (4),
491-500.
Artículo; Actas Paper
108 - Restano-Cassulini,R., Korolkova,Y.V., Diochot,S., Gurrola,G., Guasti,L., Possani,L., Lazdunski,M., Grishin,E., Arcangeli,A., Wanke,E.. Species Diversity and Peptide Toxins Blocking Selectivity of ERG Subfamily K+ Channels in CNS.
Molecular Pharmacology,
69 (5),
1673-1683.
Artículo
109 - Schiavon,E., Sacco,T., Restano-Cassulini,R., Gurrola,G., Tempia,F., Possani,L.D., Wanke,E.. Resurgent current and voltage sensor-trapping enhanced activation by a {beta}-scorpion toxin solely in nav1.6 channel: Significance in Mice Purkinje Neurons.
Journal of Biological Chemistry,
281 (29),
20326-20337.
Artículo
110 - Coronas,F.I., Balderas,C., Lopez,L.P., Possani,L.D., Gurrola,G.B.. Amino acid sequence determination and chemical synthesis of CllErg1 (gamma-KTx1.5), a K+ channel blocker peptide isolated from the scorpion Centruroides limpidus limpidus.
Journal of the Brazilian Chemical Society,
16 (3A),
404-411.
Internacional
111 - Gurrola,G.B., Zhu,X., Valdivia,H. Scorpion Peptides as High-Affinity Probes of Ryanodine Receptor Function. Ryanodine receptors : structure, function and dysfunction in clinical disease.
Developments in Cardiovascular Medicine,
191-200,
254,
New York.
Artículo
112 - Frenal,K., Xu,C.Q., Wolff,N., Wecker,K., Gurrola,G.B., Zhu,S.Y., Chi,C.W., Possani,L.D., Tytgat,J., Delepierre,M.. Exploring structural features of the interaction between the scorpion toxinCnErg1 and ERG K(+) channels.
Proteins,
56 (2),
367-375.
Artículo
113 - Rosales-Castillo,J.A., Acosta-Saavedra,L.C., Torres,R., Ochoa-Fierro,J., Borja-Aburto,V.H., Lopez-Carrillo,L., Garcia-Vargas,G.G., Gurrola,G.B., Cebrian,M.E., Calderon-Aranda,E.S.. Arsenic exposure and human papillomavirus response in non-melanoma skin cancer Mexican patients: a pilot study.
International Archives of Occupational and Environmental Health,
77 (6),
418-423.
Artículo
114 - Gazarian,T.G., Selisko,B., Gurrola,G.B., Possani,L.D., Gazarian,K.G.. Potential of Peptides Selected from Random Phage-Displayed Libraries to Mimic Conformational Epitopes: A Study on Scorpion Toxin Cn2 and the Neutralizing Monoclonal Antibody BCF2.
Combinatorial Chemistry & High Throughput Screening,
6 (2),
119-132.
Artículo
115 - Corona,M., Gurrola,G.B., Merino,E., Cassulini,R.R., Valdez-Cruz,N.A., Garcia,B, Ramirez-Dominguez,M.E., Coronas,F.I., Zamudio,F.Z., Wanke,E., Possani,L.D.. A large number of novel Ergtoxin-like genes and ERG K(+)-channels blocking peptides from scorpions of the genus Centruroides.
FEBS Letters,
532 (1-2),
121-126.
Artículo
116 - Lecchi,M., Redaelli,E., Rosati,B., Gurrola,G., Florio,T., Crociani,O., Curia,G., Cassulini,R.R., Masi,A., Arcangeli,A., Olivotto,M., Schettini,G., Possani,L.D., Wanke,E.. Isolation of a long-lasting eag-related gene-type K+ current in MMQ lactotrophs and its accommodating role during slow firing and prolactin release.
Journal of Neuroscience,
22 (9),
3414-3425.
Artículo
117 - Pardo-Lopez,L., Garcia-Valdes,J., Gurrola,G.B., Robertson,G.A., Possani,L.D.. Mapping the receptor site for ergtoxin, a specific blocker of ERG channels.
FEBS Letters,
510 (1-2),
45-49.
Artículo
118 - Frau,A., Pisciotta,M., Gurrola,G.B., Possani,L.D., Prestipino,G.. Synthetic undecapeptide (NTX10-20) of noxiustoxin blocks completely the I(A) potassium currents of cerebellum granular cells.
European Biophysics Journal,
29 (8),
569-573.
Artículo
119 - Rocchetti,M., Besana,A., Gurrola,G.B., Possani,L.D., Zaza,A.. Rate dependency of delayed rectifier currents during the guinea-pig ventricular action potential.
Journal of Physiology,
534 (Pt 3),
721-732.
Carta
120 - Bottiglieri,C., Ferrara,L., Corona,M., Gurrola,G.B., Batista,C., Wanke,E., Possani,L.D.. Disulfide bridges of ergtoxin, a member of a new sub-family of peptide blockers of the ether-a-go-go-related K+ channel.
FEBS Letters,
479 (3),
156-157 .
Artículo
121 - Torres-Larios,A., Gurrola,G.B., Zamudio,F.Z., Possani,L.D.. Hadrurin, a new antimicrobial peptide from the venom of the scorpion Hadrurus aztecus.
European Journal of Biochemistry,
267 (16),
5023-5031.
Artículo
122 - Calderon-Aranda,E.S., Selisko,B., York,E.J., Gurrola,G.B., Stewart,J.M., Possani,L.D.. Mapping of an epitope recognized by a neutralizing monoclonal antibody specific to toxin Cn2 from the scorpion Centruroides noxius, using discontinuous synthetic peptides.
European Journal of Biochemistry,
264 (3),
746-755.
Artículo
123 - Gurrola,G.B., Rosati,B., Rocchetti,M., Pimienta,G., Zaza,A., Arcangeli,A., Olivotto,M., Possani,L.D., Wanke,E.. A toxin to nervous, cardiac, and endocrine ERG K+ channels isolated from Centruroides noxius scorpion venom.
FASEB Journal,
13 (8),
953-962.
Artículo
124 - Gurrola,G.B., Arevalo,C., Sreekumar,R., Lokuta,A.J., Walker,J.W., Valdivia,H.H.. Activation of ryanodine receptors by imperatoxin A and a peptide segment of the II-III loop of the dihydropyridine receptor.
Journal of Biological Chemistry,
274 (12),
7879-7886.
*
Revisión
125 - Possani,L.D., Selisko,B., Gurrola,G.B.. Structure and function of scorpion toxins affecting K+-channels.
Perspectives In Drug Discovery And Design,
16,
15-40.
Artículo
126 - Samso,M., Trujillo,R., Gurrola,G.B., Valdivia,H.H., Wagenknecht,T.. Three-dimensional location of the imperatoxin A binding site on the ryanodine receptor.
Journal of Cell Biology,
146 (2),
493-499.
*
Artículo
127 - Zhu,X., Gurrola,G., Jiang,M.T., Walker,J.W., Valdivia,H.H.. Conversion of an inactive cardiac dihydropyridine receptor II-III loop segment into forms that activate skeletal ryanodine receptors.
FEBS Letters,
450 (3),
221-226.
*
Artículo
128 - Martinez,F., Munoz-Garay,C., Gurrola,G., Darszon,A., Possani,L.D., Becerril,B.. Site directed mutants of Noxiustoxin reveal specific interactions with potassium channels.
FEBS Letters,
429 (3),
381-384.
Artículo
Artículo
130 - Zamudio,F.Z., Gurrola,G.B., Arevalo,C., Sreekumar,R., Walker,J.W., Valdivia,H.H., Possani,L.D.. Primary structure and synthesis of Imperatoxin A (IpTx(a)), a peptide activator of Ca2+ release channels/ryanodine receptors.
FEBS Letters,
405 (3),
385-389.
Artículo
131 - Dehesa-Davila,M., Ramirez,A.N., Zamudio,F.Z., Gurrola-Briones,G., Lievano,A., Darszon,A., Possani,L.D.. Structural and functional comparison of toxins from the venom of the scorpions Centruroides infamatus infamatus, Centruroides limpidus limpidus and Centruroides noxius.
Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology,
113 (2),
331-339.
Artículo
132 - Martinez,F., Becerril,B., Gurrola,G.B., Martin,B.M., Possani,L.D.. Synthesis and expression of the gene coding for noxiustoxin, a K+ channel-blocking peptide from the venom of the scorpion Centruroides noxius.
Toxicon,
34 (11-12),
1413-1419.
Artículo
133 - Nieto,A.R., Gurrola,G.B., Vaca,L., Possani,L.D.. Noxiustoxin 2, a novel K+ channel blocking peptide from the venom of the scorpion Centruroides noxius Hoffmann.
Toxicon,
34 (8),
913-922.
Artículo
134 - Olamendi-Portugal,T., Gomez-Lagunas,F., Gurrola,G.B., Possani,L.D.. A novel structural class of K+-channel blocking toxin from the scorpion Pandinus imperator.
Biochemical Journal,
315 (Pt 3),
977-981.
Artículo
135 - Dauplais,M., Gilquin,B., Possani,L.D., Gurrola-Briones,G., Roumestand,C., Menez,A.. Determination of the three-dimensional solution structure of noxiustoxin: analysis of structural differences with related short-chain scorpion toxins.
Biochemistry,
34 (51),
16563-16573.
Artículo
136 - Drakopoulou,E., Cotton,J., Virelizier,H., Bernardi,E., Schoofs,A.R., Partiseti,M., Choquet,D., Gurrola,G., Possani,L.D., Vita,C.. Chemical synthesis, structural and functional characterisation of noxiustoxin, a powerful blocker of lymphocyte voltage-dependent K+ channels.
Biochemical and Biophysical Research Communications,
213 (3),
901-907.
Artículo
137 - Gurrola,G.B., Possani,L.D.. Structural and functional features of noxiustoxin: a K+ channel blocker.
Biochemistry and Molecular Biology International,
37 (3),
527-535.
Artículo
138 - Herion,P., Gurrola-Briones,G., Sanchez,M.D.R., Saavedra,R., Possani,L.D.. Monoclonal antibodies against noxiustoxin.
Hybridoma,
14 (3),
247-251.
Artículo
139 - Gurrola,G.B., Moreno-Hagelsieb,G., Zamudio,F.Z., Garcia,M., Soberon,X., Possani,L.D.. The disulfide bridges of toxin 2 from the scorpion Centruroides noxius Hoffmann and its three-dimensional structure calculated using the coordinates of variant 3 from Centruroides sculpturatus.
FEBS Letters,
347 (1),
59-62.
Artículo
140 - Martin,B.M., Ramirez,A.N., Gurrola,G.B., Nobile,M., Prestipino,G., Possani,L.D.. Novel K(+)-channel-blocking toxins from the venom of the scorpion Centruroides limpidus limpidus Karsch.
Biochemical Journal,
304 (Pt 1),
51-56.
Artículo
141 - Ramirez,A.N., Martin,B.M., Gurrola,G.B., Possani,L.D.. Isolation and characterization of a novel toxin from the venom of the scorpion Centruroides limpidus limpidus Karsch.
Toxicon,
32 (4),
479-490.
142 - Gurrola Briones, Georgina. Caracterizacion funcional estructural de la noxiustoxina.
Instituto de Biotecnologia,
Doctorado en Investigacion Biomedica Basica,
UNAM.
Asesor: Teran Ortiz, Luis Angel
Artículo
143 - Vaca,L., Gurrola,G.B., Possani,L.D., Kunze,D.L.. Blockade of a KCa channel with synthetic peptides from noxiustoxin: a K+ channel blocker.
Journal of Membrane Biology,
134 (2),
123-129.
Artículo
144 - Possani,L.D., Martin,B.M., Yatani,A., Mochca-Morales,J., Zamudio,F.Z., Gurrola,G.B., Brown,A.M.. Isolation and physiological characterization of taicatoxin, a complex toxin with specific effects on calcium channels.
Toxicon,
30 (11),
1343-1364.
Artículo
145 - Zamudio,F., Saavedra,R., Martin,B.M., Gurrola-Briones,G., Herion,P., Possani,L.D.. Amino acid sequence and immunological characterization with monoclonal antibodies of two toxins from the venom of the scorpion Centruroides noxius Hoffmann.
European Journal of Biochemistry,
204 (1),
281-292.
Memoria in extenso
146 - Gutierrez,M.C., Estrada,G.I., Estrada-Parra,S., Gurrola,G.B., Possani,L.D.. Synthetic peptides as skin test reagents in leprosy. Proceedings Leprosy Research in Latin America.
7 p,
Caracas.
Memoria in extenso
147 - Possani,L.D., Gurrola,G.B., Portugal,T.O., Zamudio,F.Z., Vaca,L.D., Calderon,S.A., Kirsch,G.E.. Scorpion toxins: a model for peptide synthesis of new drugs. Proceedings First Brazilian Congress on Proteins.
352-367,
Brasil.
Artículo
148 - Gurrola,G.B., Molinar-Rode,R., Sitges,M., Bayon,A., Possani,L.D.. Synthetic peptides corresponding to the sequence of noxiustoxin indicate that the active site of this K+ channel blocker is located on its amino-terminal portion.
Journal of Neural Transmission,
77 (1),
11-20.
Artículo
149 - Martin,B.M., Carbone,E., Yatani,A., Brown,A.M., Ramirez,A.N., Gurrola,G.B., Possani,L.D.. Amino acid sequence and physiological characterization of toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann.
Toxicon,
26 (9),
785-794.
Artículo
150 - Ramirez,A.N., Gurrola,G.B., Martin,B.M., Possani,L.D.. Isolation of several toxins from the venom of the scorpion Centruroides limpidus tecomanus Hoffmann.
Toxicon,
26 (9),
773-783.
Artículo
151 - Brown,A.M., Yatani,A., Lacerda,A.E., Gurrola,G.B., Possani,L.D.. Neurotoxins that act selectively on voltage-dependent cardiac calcium channels.
Circulation Research,
61 (4 Pt 2),
I6-I9.
152 - Gurrola Briones, Georgina. Sintesis quimica de peptidos correspondientes a secuencias de aminoacidos de toxinas de alacran y sus propiedades.
Instituto de Biotecnologia,
Maestro en Ciencias Quimicas (Bioquimica),
UNAM.
Asesor: Teran Ortiz, Luis Angel
Nacional
153 - Gurrola,G.B., Molina-Rode,R., Zentella,A.D., Possani,L.D.. Sintesis de peptidos y su posible utilizacion como vacuna contra toxinas de alacran. Avances en el mecanismo de accion de farmacos.
35-50.
154 - Gurrola Briones, Georgina. Busqueda e identificacion de anticuerpos contra antigenos del sistema hla .
FES Cuautitlan,
Quimico Farmaceutico Biologo,
UNAM.
*
Asesor: Teran Ortiz, Luis Angel