Dra. Maria Alejandra Bravo de la Parra
Investigadora Titular C Tiempo Completo
Microbiología Industrial utilizando proteinas bioinsecticidas
Número de registros: 30
- Activos
- Vencidos
- Análisis de la región transmembranal en la toxina cry1ab de bacillus thuringiensis, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2025 - 2027
- Análisis in vivo del mecanismo de acción de la toxina cry de bacillus thuringiensis y de las respuestas inducidas en las larvas de insectos., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2023 - 2025
- Análisis funcional de transportadores abc de lepidópteros como receptores de toxinas cry insecticidas de bacillus thuringiensis, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2022 - 2024
- Análisis de la respuesta en larvas de insectos ante el ataque de toxinas cry de bacillus thuringiensis, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2019 - 2021
- Desarrollo de nuevas toxinas insecticidas de bacillus thuringiensis contra la plagas invasivas de cultivos primordiales para méxico como maíz y algodón, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2016 - 2018
- Desarrollo de nuevas toxinas insecticidas de bacillus thuringiensis contra gusano cogollero-spodoptera frugiperda, plaga principal de cultivos de maíz mexicanos, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2016 - 2019
- Ingeniería de la toxina cyt1aa para inhibir su actividad hemolítica y optimizar su sinergismo con toxinas cry de bacillus thuringiensis, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2014 - 2018
- Mecanismos moleculares de la especificidad de las toxinas cry de bacillus thuringiensis, PRESUPUESTO UNAM, 2014 - 2020
- Papel de la oligomerización en toxinas cry y cyt de bacillus thuringiensis en su toxicidad y en el sinergismo entre estas toxinas, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2013 - 2016
- Análisis de la respuesta celular en insectos ante el ataque de las toxinas insecticidas de bacillus thuringiensis, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2011 - 2014
- Análisis molecular del proceso de oligomerización de las toxinas cry producidas por bacillus thuringiensis, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2009 - 2011
- Toxinas insecticidas de bacillus thuringiensis: eventos estructurales involucrados en la formación de poro en las células blanco y análisis de la respuesta celular a la toxina., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2006 - 2009
- Molecular recognition: the case of bacillus thuringiensis insecticidal toxins, INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY, 2006
- Mosquitocidal action of bacillus thuringiensis toxins, NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES, 2005 - 2009
- Análsis molecular del mecanismo de acción y del sinergismo entre toxinas insecticidas de bacillus thuringiensis activas contra especies de mosquitos importantes en la transmisión de enfermedades infecciosas en humanos., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2004 - 2006
- 3º reunión conjunta (fao-cyted) programa iberoamericano de ciencia y tecnología para el desarrollo., FOOD AND AGRICULTRUAL ORGANIZATION, 2002
- Selection and structure/function analysis of bacillus thuringiensis toxins active against disease-vector mosquitoes and agricultural insect pests., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2001 - 2005
- Análisis estructural y funcional de las toxinas insecticidas de bacillus thuringiensis para el cntrol biológico de especies de mosquitos importantes en la transmisión de enfermedades infecciosas en humanos., UNIVERSIDAD DE CALIFORNIA-MÉXICO, 2001 - 2002
- 2ª reunión fao-cyted, FOOD AND AGRICULTRUAL ORGANIZATION, 2001
- Desarrollo de biopesticidas autilizando bacterias entomopatológicas para el control de insectos plaga., CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 2001 - 2004
- Mejora de la actividad insecticida de delta-endotoxinas de bacilus thuringiensis activas contra insectos coleópteros., AGENCIA ESPAÑOLA DE COOPERACIÓN INTERNACIONAL, 2001 - 2002
- Efecto de las delta-endotoxinas de bacilus thringiensis sobre líneas celualres de insecto. análisis de toxicidad, formación de poro y su correlación con microdominios de la membrana plasmática (rafts)., DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 2000 - 2003
- Reunión conjunta sobre bioplaguicidas, FOOD AND AGRICULTRUAL ORGANIZATION, 2000
- Búsqueda y caracterización de proteínas biopesticidas novedosas a partir de cepas de bacillus thuringiensis, SECRETARÍA DE RELACIONES EXTERIORES, 1999 - 2002
- Participación de los dominios estructurales de las toxinas cry producidas por la bacteria bacillus trhuingiensis, en la actividad insecticida., DIRECCIÓN GENERAL DE INTERCAMBIO ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1999
- Development of new biopesticides for environmentally-friendly insect control, COMISIÓN EUROPEA, 1999 - 2002
- Análisis del mecanismo de acción de delta-endotoxinas en insectos coleópteros, AGENCIA ESPAÑOLA DE COOPERACIÓN INTERNACIONAL, 1998 - 2000
- Estudio del modo de acción de las toxinas insecticidas de bacillus thuringiensis, análisis de la inserción, oligomerización y formación de poro de estas toxinas, CONSEJO NACIONAL DE CIENCIA Y TECNOLOGÍA, 1998 - 2001
- Análisis de la inserción de la toxina cryb1ab de bacillus thuringiensis en membranas, DIRECCIÓN GENERAL DE ASUNTOS DEL PERSONAL ACADÉMICO/UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO, 1997 - 2000
- Structural and functional studies of the region alpha-helix 5 of a b. thuringiensis delta-endotoxin proposed to be involved in membrane pore formation, INTERNATIONAL FOUNDATION OF SCIENCE, 1997 - 1998
Nivel D del PRIDE
Nivel III del SNII
Nivel III del SNII
Doctorado, Investigacion Biomedica Basica, CIFN-UNAM (1989)
Maestría, Investigacion Biomedica Basica, CIFN-UNAM (1986)
Licenciatura, Investigacion Biomedica Basica, Instituto de Investigaciones Biomedicas-UNAM (1985)
Reconocimiento Griswold Lecturer, Universidad de Cornel New York USA, 2014
Medalla Omecihuatl Inmujeres, Instituto de las Mujeres de la Ciudad de México, 2013
Premio L'oreal-UNESCO Awards for Women in Science, 2010
Incluída en la lista de Expertos en Bioseguridad bajo el Protocolo de Cartagena de Seguridad y la Convención sobre Diversidad Biológica, Universidad de Colombia, 2003
Premio a la mejor Investigación en Biotecnología Agrícola, AgroBIO-México, 2003
Miembro de la Academia Nacional de Ciencias, 2002
Disitnción Universidad Nacional para Jóvenes Académicos en el área de investigación en Ciencias Naturales, UNAM, 2000
Miembro del "International cry Gene Nomenclature Committee", 1999
Premio de la Academia Mexicana de Ciencias en el área de Ciencias Naturales, 1998
- Activos
- Graduados
-
Estancia Temporal
-
Doctorado (UNAM u Otros)
-
Maestría (UNAM u Otros)
1 - Gomez Hernandez, Juan Ulises (2023). Optimizacion de la mutagenesis en los genes abca2, abcb1, abcc2 y phb2 de Aedes aegypti utilizando CRISPR-Cas9.
Instituto de Biotecnologia,
Maestro en Ciencias Bioquimicas,
UNAM.
2 - Torres Quintero, Mary Carmen (2018). Construccion de variantes de la toxina Cyt1Aa de Bacillus thuringiensis para migrar su toxicidad hacia insectos lepidopteros.
Instituto de Biotecnologia,
Doctora en Bioquimicas,
UNAM.
3 - Martínez Reynoso, Daniela Lizeth (2018). Contrucción de mutantes de la toxina Cry1Ab de Bacillus thuringiensis para analizar cambios conformacionales durante su mecanismo de acción.
Centro Universitario de Ciencias Biológicas y Agropecuarias,
Licenciado en Biología,
Universidad de Guadalajara.
*
Asesor: Bravo de la Parra, Alejandra
4 - Canton Ojeda, Pablo Emiliano (2016). Caracterizacion de los cambios transcripcionales en el intestino de aedes aegypti durante la intoxicacion con Cry11Aa de bacillus thuringiensis subsp. israelensis.
Instituto de Biotecnologia,
Doctorado en Bioquimicas,
UNAM.
Asesor: Bravo de la Parra, Alejandra
5 - Martinez de Castro Jimenez, Diana Laura (2015). Estudio de estrategias para la clonacion y expresion de toxinas cry1amod de bacillus thuringiensis.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
6 - Matus Acuna, Violeta (2014). Analisis de la oligomerizacion de la toxina cry1ab de bacillus thuringiensis.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
Asesor: Bravo de la Parra, Alejandra
7 - Martinez de Castro Jimenez, Diana Laura (2014). Optimizacion de la toxina cry1acmod de bacillus thuringiensis contra insectos lepidopteros.
Facultad de Ciencias,
Licenciatura en Biologia,
UNAM.
*
8 - Lopez Diaz, Jazmin Alaide (2013). Analisis molecular del mecanismo de accion de toxinas Cyt activas contra mosquitos.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
9 - Carmona Leon, Daniela (2011). La dominancia negativa como evidencia de heterooligomerizacion entre diferentes toxinas Cry de Bacillus thuringiensis.
Facultad de Ciencias,
Biologa,
UNAM.
*
10 - Bedoya Perez, Leidy Patricia (2011). Mecanismos de defensa en el insecto Aedes aegypti hacia el ataque de la toxina Cry11Aa de Bacillus thuringiensis.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
11 - Zavala Romero, Luis Enrique (2010). Analisis del fenotipo de dominancia negativa presentado por algunas mutantes de la helice a4 de las toxinas Cry1A.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
12 - Toro de Leon, Gerardo del (2010). Caracterizacion del espectro de accion de la toxina Cry1 A bMod, activa contra insectos resistentes, y su comparacion con la toxina convencional Cry1Ab de Bacillus thuringiensis.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
13 - Pena Chora, Guadalupe (2010). Identificacion de nuevas \03B4endotoxinas de Bacillus thuringiensis para el control de la conchuela del frijol Epilachna varivestis Musalt (Coleoptera: Coccinellidae).
Facultad de Ciencias,
Doctorado en Ciencias Biologicas,
UNAM.
*
14 - Cancino Rodezno, Maria de los Angeles (2010). Caracterizacion de la respuesta intracelular de insectos hacia las toxinas Cry de Bacillus thurigiensis.
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Bravo de la Parra, Alejandra
15 - Arroyo Loranca, Raquel Gabriela (2009). Analisis de union de toxinas Cry1A silvestres y modificadas en larvas resistentes y sensibles a toxinas Cry de Pectinophora gossypiella y Plutella xylostella.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
16 - Jimenez Juarez, Nuria (2008). Estudio del proceso de oligomerizacion de toxinas Cry1A producidas por Bacillus thuringiensis.
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
17 - Villasenor Solorio, Roberto (2007). Participacion de la ruta p38 MAPK en la respuesta a Cry11Aa de Bacillus thuringiensis en Anopheles gambiae.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
18 - Perez Ortega, Claudia Dolores (2007). Bases moleculares del sinergismo entre las delta endotoxinas Cry11Aa y Cyt1Aa de Bacillus thuringiensis subespecie israelensis.
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
19 - Lopez Gorostieta, Idalia (2006). Papel secuencial de BtR1 y aminopeptidasa N en el mecanismo de accion de las toxinas Cry de Bacillus thuringiensis.
Instituto de Biotecnologia,
Maestria en Ciencias Bioquimicas,
UNAM.
20 - Padilla Delgado, Carlos Cristopher (2005). Papel de los triptofanos en el mecanismo de accion de la toxina Cry1Ab de Bacillus thuringiensis.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
21 - Lopez Gorostieta, Idalia (2004). Silenciamiento de Bt R1 y aminopeptidasa N de Manduca sexta, por medio de RNA de doble cadena y su papel como receptores de las toxinas Cry de Bacillus thuringiensis.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
22 - Perez Ortega, Claudia Dolores (2003). Analisis molecular del sinergismo entre las &endotoxinas Cry11A y Cyt1a de bacillus thuringiensis subespecie israelensis.
Instituto de Biotecnologia,
Maestria en Ciencias (Bioquimica),
UNAM.
Asesor: Bravo de la Parra, Ma Alejandra
23 - Hernandez Montes, Georgina (2002). Determinacion del papel de los triptofanos en el mecanismo de accion de la proteina Cry 1 Ab de Bacillus thuringiensis.
Instituto de Biotecnologia,
Maestroia en Ciencias (Bioquimica),
UNAM.
Asesor: Bravo de la Parra, Ma Alejandra
24 - Conde Guzman, Juan (2002). Caracterizacion de mutantes en el dominio II de la toxina insecticida Cry1Ca de Bacillus thuringiensis.
Facultad de Ciencias,
Licenciatura en Biología,
UNAM.
*
25 - Miranda Caso Luengo, Raul (2001). Analisis de la estructura y el procesamiento proteolitico de la toxina Cry1Ab de Bacillus thuringiensis.
Instituto de Biotecnologia,
Doctorado en Ciencias Bioquimicas,
UNAM.
Asesor: Bravo de la Parra, Alejandra
26 - Tenorio Salgado, Silvia (2000). Analisis comparativo de la actividad formadora de poro de diferentes & endotoxinas de Bacillus thuringiensis.
Instituto de Biotecnologia,
Maestria en Ciencias (Bioquimica),
UNAM.
Asesor: Bravo de la Parra, Ma Alejandra
27 - Meza Romero, Roberto (1997). Mutagenesis sitiodirigida de una region hidrofobica de la toxina Cry1Ab de Bacillus thuringiensis spp berliner.
Instituto de Biotecnologia,
Doctorado en Biotecnologia,
UNAM.
Asesor: Bravo de la Parra, Ma Alejandra
28 - Lorence Quinones, Argelia (1997). Analisis de la actividad de formacion de poro de las proteinas Cry de Bacillus thuringiensis en presencia de su receptor nativo.
Instituto de Biotecnologia,
Doctorado en Biotecnologia,
UNAM.
Asesor: Bravo de la Parra, Ma Alejandra
29 - Lorence Quinones, Argelia (1995). Diseno de un sistema de deteccion de nuevas delta endotoxinas de Bacillus thuringiensis.
Instituto de Biotecnologia,
Maestria en Biotecnologia,
UNAM.
Asesor: Quintero Ramirez, Rodolfo, Bravo de la Parra, Alejandra
30 - Diaz Camino, Claudia (1995). Mecanismo de accion de las delta Endotoxinas de Bacillus thuringiensis.
Instituto de Biotecnologia,
Maestria en Biotecnologia,
UNAM.
Asesor: Bravo de la Parra, Ma Alejandra
31 - Ceron Salamanca, Jairo Alonso (1995). Busqueda y caracterizacion de nuevos genes de Jendotoxina de Bacillus thuringiensis.
Instituto de Biotecnologia,
Doctorado en Biotecnologia,
UNAM.
32 - Ceron Salamanca, Jairo Alonso (1991). Establecimiento de estrategias para la caracterizacion y manipulacion genetica de cepas de Bacillus thuringiensis.
Centro de Investigacion sobre Ingenieria Genetica y Biotecnologia,
Maestria en Biotecnologia,
UNAM.
* Indica publicación con otra institución de adscripción
Total de publicaciones: 283
- Tipo
- Fecha
Revisión
33 - Crickmore,N., Bravo,A., Heckel,D., Hernandez-Martinez,P., Nielsen-LeRoux,C., Soberon,M. (2026). How Bacillus thuringiensis kills its insect host.
Journal of Invertebrate Pathology,
218 (September),
108643.
Artículo
34 - do Nascimento,N.A., Torres-Quintero,M.C., Garcia-Gomez,B.I., Gomez,I., Pacheco,S., Bravo,A., Soberon,M. (2026). Engineering Bacillus thuringiensis Cyt1Aa to function as a surrogate receptor of Cry1A lepidopteran insecticidal proteins.
Pesticide Biochemistry And Physiology,
219 (April),
106970,
[Correction 107201 2026].
Artículo
35 - Gomez,I., Garcia-Gomez,B.I., do Nascimento,N.A., Infante,O., Canton,P.E., Pacheco,S., Pelaez-Aguilar,A.E., Sanchez,J., Soberon,M., Bravo,A. (2026). Regulatory diversity in Bacillus thuringiensis cry genes reveals flexible evolutionary strategies for in vivo toxin expression.
PLoS Pathogens,
22 (3),
e1014017.
Artículo
36 - Kang,S., Bai,Y., Crickmore,N., Soberon,M., Zhou,X., Zhang,Y., Bravo,A., Guo,Z. (2026). From gatekeeper to target: MAPK cascades as control circuits at the insect-microbe interface.
FEMS Microbiology Reviews,
50,
fuag027.
Artículo
37 - Quintana,A.J., Garcia-Suarez,R., Prieto,A., Sanchez,J., Gomez,I., Verduzco-Rosas,L.A., doNascimento,N., Lopez-Molina,S., Zhang,J., Soberon,M., Bravo,A., Pacheco,S. (2026). Genome editing of ABCB6 Transporter Confers Resistance to Cypermethrin in the Major Pest of Corn, Spodoptera frugiperda.
Insect Biochemistry and Molecular Biology,
190 (May),
104537.
Revisión
38 - Sun,M., Shi,J., Bravo,A. (2026). Caenorhabditis elegans: A Model System for Accelerating Studies on Bacillus thuringiensis Infection in Insects.
Annual Review of Entomology,
71 (1),
597-614.
Artículo
39 - Zhang,B., Liu,Z., Zhang,H., Bravo,A., Soberon,M., Zheng,J., Sun,M., Wang,K., Song,F., Peng,D. (2026). Bacillus thuringiensis pathogenicity islands encode regulatory circuits controlling insecticidal Cry toxin expression during vegetative growth.
PLoS Pathogens,
22 (7),
e1014476.
Artículo
40 - Zhou,H., Li,Lixu, Gong,Y., Liu,H., Wu,H., Bravo,A., Soberon,M., Zheng,J., Peng,D., Sun,Bo, Sun,M. (2026). Geographic and Seasonal Variation of Culturable Bacteria Associated with the Diseased Silkworm (Bombyx mori).
Current Research in Microbial Sciences,
10,
100529.
Artículo
41 - Huang,G., Wang,K., Li,F., Gao,S., Liu,H., Chen,F., Liu,Z., Chen,Y., Wang,C., Xu,M., Hu,B., Xie,C., Ma,Y., Dai,D., Li,Y., Li,X., Bo,D., Chen,L., Bravo,A., Soberon,M., Zheng,J., Peng,D., Sun,M. (2025). Large-scale protein interactome reveals lineage-specific genes driving plant-parasitic nematode adaptive innovations.
Science Advances,
11 (33),
eadt5107.
Artículo
42 - Li,S., Wang,Z., Yang,Y., Niu,X., Fang,Y., Soberon,M., Bravo,A., Wu,G.X., Zhang,J. (2025). Sequestosome 1 in Autophagy Regulates a Defense Response of the Striped Stem Borer to the Cry9Aa Protein.
Journal of Agricultural and Food Chemistry,
73 (18),
11030-11040.
Artículo
43 - Lopez-Molina,S., Guerrero,A., Pacheco,S., Wang,Z., Zhang,J., Sanchez,J., Zavala,G., Soberon,M., Bravo,A. (2025). Cry11Aa toxin of Bacillus thuringiensis interactions with intracellular organelles in insect gut implicating actin depolymerization, massive endocytosis, and vesicle secretion.
International Journal of Biological Macromolecules,
314,
144350.
Artículo
44 - Pacheco,S., Chinas,M., Gomez,J.U., Pelaez-Aguilar,A.E., do Nascimento,N.A., Canton,P.E., Sanchez,J., Lopez-Molina,S., Gomez,I., Soberon,M., Bravo,A. (2025). ABC transporters knockout in Aedes aegypti induces upregulation of paralogous genes, avoiding resistance development to Bacillus thuringiensis Cry toxins.
PLoS ONE,
20 (7),
e0327221.
Artículo
45 - Sun,D., Xu,Q.C., Guo,L., Bai,Y., Shentu,X., Yu,X., Crickmore,N., Zou,X.G., Bravo,A., Soberon,M., Zhang,Y.J., Guo,Z.J. (2025). The role of GPI-anchored membrane-bound alkaline phosphatase in the mode of action of Bt Cry1A toxins in the diamondback moth.
Fundamental Research,
5 (2),
674-682.
Artículo
46 - Tan,S., Shang,Z., Jia,H., Huang,J., Geng,L., Shu,C., Soberon,M., Bravo,A., Shi,W., Zhang,J., Wei,H. (2025). Enhancing Bacillus thuringiensis Cry8Ea1 toxicity: Insights into protease sensitivity for the evolutionary adaptation of Cry toxins to insect hosts.
International Journal of Biological Macromolecules,
308 (1),
142246.
Artículo
47 - Wang,K., Xu,J., Lu,X., Yin,P., Chen,L., Zhao,Z., Bravo,A., Soberon,M., Zheng,J., Sun,M., Peng,D. (2025). Two novel trimethoprim resistance genes, dfra50 and dfra51, identified in phage-plasmids.
Antimicrobial Agents and Chemotherapy,
69 (7),
e0169524.
Artículo
48 - Wang,K., Xu,J., Li,X., Zhu,P., Suo,R., Lu,X., Luo,H., Chen,L., Wen,R., Zheng,C., Bravo,A., Soberon,M., Zheng,J., Sun,M., Peng,D. (2025). Evolutionary selection of trimethoprim-resistant dfrA genes in lytic phages affects phage and host fitness during infection.
Science Advances,
11 (39),
eadt4817.
Artículo
49 - de Oliveira,J.L., Gomez,I., Sanchez,J., Soberon,M., Polanczyk,R.A., Bravo,A. (2024). Performance insights into spray-dryer microencapsulated Bacillus thuringiensis cry pesticidal proteins with gum arabic and maltodextrin for effective pest control.
Applied Microbiology and Biotechnology,
108 (1),
181.
Artículo
50 - He,X., Yang,Y., Soberon,M., Bravo,A., Zhang,L., Zhang,J., Wang,Z. (2024). Bacillus thuringiensis Cry9Aa Insecticidal Protein Domain I Helices In3 and In4 Are Two Core Regions Involved in Oligomerization and Toxicity.
Journal of Agricultural and Food Chemistry,
72 (2),
1321-1329.
Artículo
51 - Huang,G., Cong,Z., Liu,Z., Chen,F., Bravo,A., Soberon,M., Zheng,J., Peng,D., Sun,M. (2024). Silencing Ditylenchus destructor cathepsin L-like cysteine protease has negative pleiotropic effect on nematode ontogenesis.
Scientific Reports,
14 (1),
10030.
Artículo
52 - Infante,O., Gomez,I., Pelaez-Aguilar,A.E., Verduzco-Rosas,L.A., Garcia-Suarez,R., Garcia-Gomez,B.I., Wang,Z., Zhang,J., Guerrero,A., Bravo,A., Soberon,M. (2024). Insights into the structural changes that trigger receptor binding upon proteolytic activation of Bacillus thuringiensis Vip3Aa insecticidal protein.
PLoS Pathogens,
20 (12),
e1012765,
[Correction e1014366, 2026].
Artículo
53 - Pacheco,S., Gallegos,A.S., Pelaez-Aguilar,A.E., Sanchez,J., Gomez,I., Soberon,M., Bravo,A. (2024). CRISPR-Cas9 knockout of membrane-bound alkaline phosphatase or cadherin does not confer resistance to Cry toxins in Aedes aegypti.
PLoS Neglected Tropical Diseases,
18 (6),
e0012256.
Artículo
54 - Wang,H.X., Li,A.J., Bian,H.R., Jin,L., Ma,S.L., Wang,H.Y., Yang,Y.B., Bravo,A., Soberon,M., Liu,K.Y. (2024). Transcriptional regulation of Cry2Ab toxin receptor ABCA2 gene in insects involves GATAe and splicing of ant 5' UTR iron.
Pesticide Biochemistry And Physiology,
206,
106211.
Artículo
55 - Wang,Z., Yang,Y., Li,S., Ma,W., Wang,K., Soberon,M., Yan,Sh., Shen,J., Francis,F., Bravo,A., Zhang,J. (2024). JAK/STAT signaling regulated intestinal regeneration defends insect pests against pore-forming toxins produced by Bacillus thuringiensis.
PLoS Pathogens,
24 (20),
e1011823.
Artículo
56 - Chen,F., Pang,C., Zheng,Z., Zhou,W., Guo,Z., Xiao,D., Du,H., Bravo,A., Soberon,M., Sun,M., Peng,D. (2023). Aminopeptidase MNP-1 triggers intestine protease production by activating daf-16 nuclear location to degrade pore-forming toxins in Caenorhabditis elegans.
PLoS Pathogens,
19 (7),
e1011507.
Artículo
57 - Garcia-Gomez,B.I., Sanchez,T.A., Cano,S.N., do Nascimento,N.A., Bravo,A., Soberon,M. (2023). Insect chaperones Hsp70 and Hsp90 cooperatively enhance toxicity of Bacillus thuringiensis Cry1A toxins and counteract insect resistance.
Frontiers in Immunology,
14,
1151943.
Artículo
58 - Pacheco,S., Gomez,I., Soberon,M., Bravo,A. (2023). A major conformational change of N-terminal helices of Bacillus thuringiensis Cry1Ab insecticidal protein is necessary for membrane insertion and toxicity.
Febs Journal,
290 (10),
2692-2705.
Revisión
59 - Pacheco,S., Gomez,I., Pelaez-Aguilar,A.E., Verduzco-Rosas,L.A., Garcia-Suarez,R., do Nascimento,N.A., Rivera-Najera,L.Y., Canton,P.E., Soberon,M., Bravo,A. (2023). Structural changes upon membrane insertion of the insecticidal pore-forming toxins produced by Bacillus thuringiensis.
Frontiers in Insect Science,
3,
1188891.
Artículo
60 - Velasquez C,L.F., Canton,P.E., Sanchez-Flores,A., Soberon,M., Bravo,A., Ceron S,J.A. (2023). Identification of Cry toxin receptor genes homologs in a de novo transcriptome of Premnotrypes vorax (Coleoptera: Curculionidae).
PLoS ONE,
18 (9),
e0291546.
Artículo
61 - Wang,K., Shu,C., Bravo,A., Soberon,M., Zhang,H., Crickmore,N., Zhang,J. (2023). Development of an Online Genome Sequence Comparison Resource for Bacillus cereus sensu lato Strains Using the Efficient Composition Vector Method.
Toxins (Basel),
15 (6),
393.
Artículo
62 - Wei,W., Wang,L., Pan,S., Wang,H., Xia,Z., Liu,L., Xiao,Y., Bravo,A., Soberon,M., Yang,Y., Liu,K. (2023). Helicoverpa armigera GATAe transcriptional factor regulates the expression of Bacillus thuringiensis Cry1Ac receptor gene ABCC2 by its interplay with additional transcription factors.
Pesticide Biochemistry And Physiology,
194,
105516.
Revisión
63 - do Nascimento,J., Goncalves,K.C., Dias,N.P., de Oliveira,J.L., Bravo,A., Polanczyk,R.A. (2022). Adoption of Bacillus thuringiensis-based biopesticides in agricultural systems and new approaches to improve their use in Brazil.
Biological Control,
165,
104792.
Artículo
64 - Guo,L., Cheng,Z., Qin,J., Sun,D., Wang,S., Wu,Q., Crickmore,N., Zhou,X., Bravo,A., Soberon,M., Guo,Z., Zhang,Y. (2022). MAPK-mediated transcription factor GATAd contributes to Cry1Ac resistance in diamondback moth by reducing PxmALP expression.
PLoS Genetics,
18 (2),
e1010037.
Artículo
65 - Guo,Z., Guo,L., Qin,J., Ye,F., Sun,D., Wu,Q., Wang,S., Crickmore,N., Zhou,X., Bravo,A., Soberon,M., Zhang,Y. (2022). A single transcription factor facilitates an insect host combating Bacillus thuringiensis infection while maintaining fitness.
Nature Communications,
13 (1),
6024.
Artículo
66 - Liao,C., Jin,M., Cheng,Y., Yang,Y., Soberon,M., Bravo,A., Liu,K., Xiao,Y. (2022). Bacillus thuringiensis Cry1Ac Protoxin and Activated Toxin Exert Differential Toxicity Due to a Synergistic Interplay of Cadherin with ABCC Transporters in the Cotton Bollworm.
Applied and Environmental Microbiology,
88 (7),
e0250521.
Artículo
67 - Sun,D., Zhu,L., Guo,L., Wang,S., Wu,Q., Crickmore,N., Zhou,X., Bravo,A., Soberon,M., Guo,Z., Zhang,Y. (2022). A versatile contribution of both aminopeptidases N and ABC transporters to Bt Cry1Ac toxicity in the diamondback moth.
BMC Biology,
20 (1),
33.
Revisión
68 - de Oliveira,J.L., Fraceto,L.F., Bravo,A., Polanczyk,R.A. (2021). Encapsulation Strategies for Bacillus thuringiensis: From Now to the Future.
Journal of Agricultural and Food Chemistry,
69 (16),
4564-4577.
Artículo
69 - Guo,Z., Kang,S., Wu,Q., Wang,S., Crickmore,N., Zhou,X., Bravo,A., Soberon,M., Zhang,Y. (2021). The regulation landscape of MAPK signaling cascade for thwarting Bacillus thuringiensis infection in an insect host.
PLoS Pathogens,
17 (9),
e1009917.
Artículo
70 - Jin,M., Yang,Y., Shan,Y., Chakrabarty,S., Cheng,Y., Soberon,M., Bravo,A., Liu,K., Wu,K., Xiao,Y. (2021). Two ABC transporters are differentially involved in the toxicity of two Bacillus thuringiensis Cry1 toxins to the invasive crop-pest Spodoptera frugiperda (J. E. Smith).
Pest Management Science,
77 (3),
1492-1501.
Artículo
71 - Liu,Y., Jin,M., Wang,L., Wang,H., Xia,Z., Yang,Y., Bravo,A., Soberon,M., Xiao,Y., Liu,K. (2021). SfABCC2 transporter extracellular loops 2 and 4 are responsible for the Cry1Fa insecticidal specificity against Spodoptera frugiperda.
Insect Biochemistry and Molecular Biology,
135,
103608.
Artículo
72 - Lopez-Molina,S., do Nascimento,N.A., Silva-Filha,M.H.N.L., Guerrero,A., Sanchez,J., Pacheco,S., Gill,S.S., Soberon,M., Bravo,A. (2021). In vivo nanoscale analysis of the dynamic synergistic interaction of Bacillus thuringiensis Cry11Aa and Cyt1Aa toxins in Aedes aegypti.
PLoS Pathogens,
17 (1),
e1009199.
Artículo
73 - Pacheco,S., Gomez,I., Chinas,M., Sanchez,J., Soberon,M., Bravo,A. (2021). Whole Genome Sequencing Analysis of Bacillus thuringiensis GR007 Reveals Multiple Pesticidal Protein Genes.
Frontiers in Microbiology,
12,
3268.
Artículo
74 - Sena da Silva,I.H., Gomez,I., Pacheco,S., Sanchez,J., Zhang,J., Luque Castellane,T.C., Aparecida Desiderio J., Soberon,M., Bravo,A., Polanczyk,R.A. (2021). Bacillus thuringiensis Cry1Ab domain III -16 is involved in binding to prohibitin which correlates with toxicity against Helicoverpa armigera (Lepidoptera: Noctuidae).
Applied and Environmental Microbiology,
87 (2),
e01930-20.
Artículo
75 - Shi,J., Zhang,F., Chen,L., Bravo,A., Soberon,M., Sun,M. (2021). Systemic mitochondrial disruption is a key event in the toxicity of bacterial pore-forming toxins to Caenorhabditis elegans.
Environmental Microbiology,
23 (9),
4896-4907.
Revisión
76 - Silva-Filha,M.H.N.L., Romao,T.P., Rezende,T.M.T., Carvalho,K.D.S., de Menezes,H.S.G., do Nascimento,N.A., Soberon,M., Bravo,A. (2021). Bacterial toxins active against mosquitoes: Mode of action and resistance.
Toxins,
13 (8),
523.
Artículo
77 - Wang,Z., Gan,C., Wang,J., Bravo,A., Soberon,M., Yang,Q., Zhang,J. (2021). Nutrient conditions determine the localization of Bacillus thuringiensis Vip3Aa protein in the mother cell compartment.
Microbial Biotechnology,
14 (1),
551-560.
Artículo
78 - Xiao,Y., Li,W., Yang,X., Xu,P., Jin,M., Yuan,H., Zheng,W., Soberon,M., Bravo,A., Wilson,K., Wu,K. (2021). Rapid spread of a densovirus in a major crop pest following wide-scale adoption of Bt-cotton in China.
Elife,
10,
e66913.
Artículo
79 - Yang,Y., Huang,X., Yuan,W., Xiang,Y., Guo,X., Wei,W., Soberon,M., Bravo,A., Liu,K. (2021). Bacillus thuringiensis cry toxin triggers autophagy activity that may enhance cell death.
Pesticide Biochemistry And Physiology,
171,
104728.
Artículo
80 - Zhang,D., Jin,M., Yang,Y., Zhang,J., Yang,Y., Liu,K., Soberon,M., Bravo,A., Xiao,Y., Wu,K. (2021). Synergistic resistance of Helicoverpa armigera to Bt toxins linked to cadherin and ABC transporters mutations.
Insect Biochemistry and Molecular Biology,
137,
103635.
Artículo
81 - Anaya,P., Onofre,J., Torres-Quintero,M.C., Sanchez,J., Gill,S.S., Bravo,A., Soberon,M. (2020). Oligomerization is a key step for Bacillus thuringiensis Cyt1Aa insecticidal activity but not for toxicity against red blood cells.
Insect Biochemistry and Molecular Biology,
119,
103317.
Artículo
82 - do Nascimento,N.A., Torres-Quintero,M.C., Lopez-Molina,S., Pacheco,S., Romao,T.P., Pereira-Neves,A., Soberon,M., Bravo,A., Silva-Filha,M.H.N.L. (2020). Functional Bacillus thuringiensis Cyt1Aa is necessary to synergize Lysinibacillus sphaericus Binary toxin against Bin-resistant and refractory mosquito species.
Applied and Environmental Microbiology,
86 (7),
02770-19.
Artículo
83 - Gomez,I., Ocelotl,J., Sanchez,J., Aguilar-Medel,S., Pena-Chora,G., Lina-Garcia,L., Bravo,A., Soberon,M. (2020). Bacillus thuringiensis Cry1Ab domain III beta-22 mutants with enhanced toxicity to Spodoptera frugiperda (J. E. Smith).
Applied and Environmental Microbiology,
86 (22),
e01580-20.
Artículo
84 - Gong,L., Kang,S., Zhou,J., Sun,D., Guo,L., Qin,J., Zhu,L., Bai,Y., Ye,F., Akami,M., Wu,Q., Wang,S., Xu,B., Yang,Z., Bravo,A., Soberon,M., Guo,Z., Wen,L., Zhang,Y. (2020). Reduced Expression of a Novel Midgut Trypsin Gene Involved in Protoxin Activation Correlates with Cry1Ac Resistance in a Laboratory-Selected Strain of Plutella xylostella (L.).
Toxins (Basel),
12 (2).
Artículo
85 - Guo,Z., Gong,L., Kang,S., Zhou,J., Sun,D., Qin,J., Guo,L., Zhu,L., Bai,Y., Bravo,A., Soberon,M., Zhang,Y. (2020). Comprehensive analysis of Cry1Ac protoxin activation mediated by midgut proteases in susceptible and resistant Plutella xylostella (L.).
Pesticide Biochemistry And Physiology,
163,
23-30.
Artículo
86 - Onofre,J., Pacheco,S., Torres-Quintero,M.C., Gill,S.S., Soberon,M., Bravo,A. (2020). The Cyt1Aa toxin from Bacillus thuringiensis inserts into target membranes via different mechanisms in insects, red blood cells, and lipid liposomes.
Journal of Biological Chemistry,
295 (28),
9606-9617.
Artículo
87 - Pacheco,S., Quiliche,J.P.J., Gomez,I., Sanchez,J., Soberon,M., Bravo,A. (2020). Rearrangement of N-Terminal alpha-Helices of Bacillus thuringiensis Cry1Ab Toxin Essential for Oligomer Assembly and Toxicity.
Toxins (Basel),
12 (10),
E647.
Artículo
88 - Shabbir,M.Z., Zhang,T., Prabu,S., Wang,Y.Q., Wang,Z.Y., Bravo,A., Soberon,M., He,K. (2020). Identification of Cry1Ah-binding proteins through pull down and gene expression analysis in Cry1Ah-resistant and susceptible strains of Ostrinia furnacalis.
Pesticide Biochemistry And Physiology,
163,
200-208.
Artículo
89 - Shu,C., Yan,G., Huang,S., Geng,Y., Soberon,M., Bravo,A., Geng,L., Zhang,J. (2020). Characterization of Two Novel Bacillus thuringiensis Cry8 Toxins Reveal Differential Specificity of Protoxins or Activated Toxins against Chrysomeloidea Coleopteran Superfamily.
Toxins (Basel),
12 (10).
Artículo
90 - Wang,Z., Wang,K., Bravo,A., Soberon,M., Cai,J., Shu,C., Zhang,J. (2020). Coexistence of cry9 with the vip3A Gene in an Identical Plasmid of Bacillus thuringiensis Indicates Their Synergistic Insecticidal Toxicity.
Journal of Agricultural and Food Chemistry,
68 (47),
14081-14090.
Artículo
91 - Wei,W., Pan,S., Ma,Y., Xiao,Y., Yang,Y., He,S., Bravo,A., Soberon,M., Liu,K. (2020). GATAe transcription factor is involved in Bacillus thuringiensis Cry1Ac toxin receptor gene expression inducing toxin susceptibility.
Insect Biochemistry and Molecular Biology,
118,
103306.
Artículo
92 - Zhang,J., Jin,M., Yang,Y., Liu,L., Yang,Y., Gomez,I., Bravo,A., Soberon,M., Xiao,Y., Liu,K. (2020). The Cadherin Protein Is Not Involved in Susceptibility to Bacillus thuringiensis Cry1Ab or Cry1Fa Toxins in Spodoptera frugiperda.
Toxins (Basel),
12 (6),
375.
Artículo
93 - Zheng,Z., Zhang,Y., Liu,Z., Dong,Z., Xie,C., Bravo,A., Soberon,M., Mahillon,J., Sun,M., Peng,D. (2020). The CRISPR-Cas systems were selectively inactivated during evolution of Bacillus cereus group for adaptation to diverse environments.
ISME Journal,
14 (6),
1479-1493.
Artículo
94 - Garcia-Gomez,B.I., Cano,S.N., Zagal,E.E., Dantan-Gonzalez,E., Bravo,A, Soberon,M (2019). Insect Hsp90 Chaperone Assists Bacillus thuringiensis Cry Toxicity by Enhancing Protoxin Binding to the Receptor and by Protecting Protoxin from Gut Protease Degradation.
MBio,
10 (6),
e02775-19.
Artículo
95 - Ma,Y., Zhang,J., Xiao,Y., Yang,Y., Liu,C., Peng,R., Yang,Y., Bravo,A., Soberon,M., Liu,K. (2019). The Cadherin Cry1Ac Binding-Region is Necessary for the Cooperative Effect with ABCC2 Transporter Enhancing Insecticidal Activity of Bacillus thuringiensis Cry1Ac Toxin.
Toxins (Basel),
11 (9),
538.
Artículo
96 - Wan,L., Lin,J., Du,H., Bravo,A., Soberon,M., Sun,M. (2019). Bacillus thuringiensis targets the host intestinal epithelial junctions for successful infection of Caenorhabditis elegans.
Environmental Microbiology,
21 (3),
1086-1098.
Artículo
97 - Bravo,A., Lopez-Diaz,J.A., Yamamoto,T., Harding,K., Zhao,J.J., Mendoza,G., Onofre,J., Torres,M.C., Nelson,M.E., Wu,G., Sethi,A., Soberon,M. (2018). Susceptible and mCry3A resistant corn rootworm larvae killed by a non-hemolytic Bacillus thuringiensis Cyt1Aa mutant.
Scientific Reports,
8 (1),
17805.
Artículo
98 - Gomez, I., Rodriguez-Chamorro, D.E., Flores-Ramirez, G., Grande, R., Zuniga, F., Portugal, F.J., Sanchez, J., Pacheco, S., Bravo, A., Soberon, M. (2018). Spodoptera frugiperda (J. E. Smith) aminopeptidase N1 is functional receptor of Bacillus thuringiensis Cry1Ca toxin.
Applied and Environmental Microbiology,
84 (17),
UNSP e01089-18.
Artículo
99 - Gomez, I., Ocelotl, J., Sanchez, J., Lima, C., Martins, E., Rosales-Juarez, A., Aguilar-Medel, S., Abad, A., Dong, H., Monnerat, R., Pena, G., Zhang, J., Nelson, M., Wu, G., Bravo, A., Soberon, M. (2018). Enhancement of Bacillus thuringiensis Cry1Ab and Cry1Fa toxicity to Spodoptera frugiperda by domain III mutations indicates two limiting steps in toxicity as defined by receptor binding and protein stability.
Applied and Environmental Microbiology,
84 (20),
e01393-18.
Artículo
100 - Liu, L., Chen, Z., Yang, Y., Xiao, Y., Liu, C., Ma, Y., Soberon, M., Bravo, A., Yang, Y., Liu, K. (2018). A single amino acid polymorphism in ABCC2 loop 1 is responsible of differential toxicity of Bacillus thuringiensis Cry1Ac toxin in different Spodoptera (Noctuidae) species.
Insect Biochemistry and Molecular Biology,
100,
59-65.
Artículo
101 - Liu, Y., Wang, Y., Shu, C., Lin, K., Song, F., Bravo, A., Soberon, M., Zhang, J. (2018). Cry64Ba and Cry64Ca, two ETX/MTX2 Bacillus thuringiensis insecticidal proteins against hemipteran pests.
Applied and Environmental Microbiology,
84 (3),
e01996-17.
Artículo
102 - Pacheco, S., Gomez, I., Sanchez, J., Garcia-Gomez, B.I., Czajkowsky, D.M., Zhang, J., Soberon, M., Bravo, A. (2018). Helix alpha-3 inter-molecular salt bridges and conformational changes are essential for toxicity of Bacillus thuringiensis 3D-Cry toxin family.
Scientific Reports,
8 (1),
10331.
Artículo
103 - Pena-Cardena,A., Grande,R., Sanchez,J., Tabashnik,B.E., Bravo,A., Soberon,M., Gomez,I. (2018). The C-terminal protoxin domain of Bacillus thuringiensis Cry1Ab toxin has a functional role in binding to GPI-anchored receptors in the insect midgut.
Journal of Biological Chemistry,
293 (52),
20263-20272.
Artículo
104 - Rocha-Munive, M.G., Soberon, M., Castaneda, S., Niaves, E., Scheinvar, E., Eguiarte, L.E., Mota-Sanchez, D., Rosales-Robles, E., Nava-Camberos, U., Martinez-Carrillo, J.L., Blanco, C.A., Bravo, A., Souza, V. (2018). Evaluation of the Impact of Genetically Modified Cotton After 20 Years of Cultivation in Mexico.
Frontiers in Bioengineering and Biotechnology,
6,
82.
Artículo
105 - Sena de Silva,I., Gomez,I., Sanchez,J., Martinez de Castro,D.L., Valicente,F.H., Soberon,M., Polanczyk,R.A., Bravo,A. (2018). Identification of midgut membrane proteins from different instars of Helicoverpa armigera (Lepidoptera: Noctuidae) that bind to Cry1Ac toxin.
PLoS ONE,
13 (12),
e0207789.
Artículo
106 - Shabbir, M.Z., Quan, Y., Wang, Z., Bravo, A., Soberon, M., He, K. (2018). Characterization of the Cry1Ah resistance in Asian corn Borer and its cross-resistance to other Bacillus thuringiensis toxins.
Scientific Reports,
8 (1),
234.
Revisión
107 - Soberon, M., Portugal, L., Garcia-Gomez, B.I., Sanchez, J., Onofre, J., Gomez, I., Pacheco, S., Bravo, A. (2018). Cell lines as models for the study of Cry toxins from Bacillus thuringiensis.
Insect Biochemistry and Molecular Biology,
93,
66-78.
Artículo
108 - Torres-Quintero, M.C., Gomez, I., Pacheco, S., Sanchez, J., Flores, H., Osuna, J., Mendoza, G., Soberon, M., Bravo, A. (2018). Engineering Bacillus thuringiensis Cyt1Aa toxin specificity from dipteran to lepidopteran toxicity.
Scientific Reports,
8 (1),
4989.
Artículo
109 - Wang, K., Shu, C., Soberon, M., Bravo, A., Zhang, J. (2018). Systematic characterization of Bacillus Genetic Stock Center Bacillus thuringiensis strains using Multi-Locus Sequence Typing.
Journal of Invertebrate Pathology,
155,
5-13.
Artículo
110 - Wang, Z., Fang, L., Zhou, Z., Pacheco, S., Gomez, I., Song, F., Soberon, M., Zhang, J., Bravo, A. (2018). Specific binding between Bacillus thuringiensis Cry9Aa and Vip3Aa toxins synergizes their toxicity against Asiatic rice borer (Chilo suppressalis).
Journal of Biological Chemistry,
293 (29),
11447-11458.
Artículo
111 - Chen, W.B., Lu, G.Q., Cheng, H.M., Liu, C.X., Xiao, Y.T., Xu, C., Shen, Z.C., Soberon, M., Bravo, A., Wu, K.M. (2017). Transgenic cotton co-expressing chimeric Vip3AcAa and Cry1Ac confers effective protection against Cry1Ac-resistant cotton bollworm.
Transgenic Research,
26 (6),
763-774.
Artículo
112 - Jiang, J., Huang, Y., Shu, C., Soberon, M., Bravo, A., Liu, C., Song, F., Lai, J., Zhang, J. (2017). Holotrichia oblita Midgut Proteins That Bind to Bacillus thuringiensis Cry8-Like Toxin and Assembly of the H. oblita Midgut Tissue Transcriptome.
Applied and Environmental Microbiology,
83 (12),
e00541-17.
Artículo
113 - Li, J., Ma, Y., Yuan, W., Xiao, Y., Liu, C., Wang, J., Peng, J., Peng, R., Soberon, M., Bravo, A., Yang, Y., Liu, K. (2017). FOXA transcriptional factor modulates insect susceptibility to Bacillus thuringiensis Cry1Ac toxin by regulating the expression of toxin-receptor ABCC2 and ABCC3 genes.
Insect Biochemistry and Molecular Biology,
88,
1-11.
Artículo
114 - Martinez de Castro, D.L, Garcia-Gomez, B.I., Gomez, I., Bravo, A., Soberon, M. (2017). Identification of Bacillus thuringiensis Cry1AbMod binding-proteins from Spodoptera frugiperda.
Peptides,
98,
99-105.
Artículo
115 - Ocelotl, J., Sanchez, J., Gomez, I., Tabashnik, B.E., Bravo, A., Soberon, M. (2017). ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth.
Scientific Reports,
7 (1),
2386.
Artículo; Actas Paper
116 - Onofre, J., Gaytan, M.O., Pena-Cardena, A., Garcia-Gomez, B.I., Pacheco, S., Gomez, I., Bravo, A., Soberon, M. (2017). Identification of Aminopeptidase-N2 as a Cry2Ab binding protein in Manduca sexta.
Peptides,
98,
93-98.
Artículo
117 - Pacheco, S., Gomez, I., Sanchez, J., Garcia-Gomez, B.I., Soberon, M., Bravo, A. (2017). Intra-molecular salt bridge in Bacillus thuringiensis Cry4Ba toxin is involved in the stability of helix alpha-3 that is needed for oligomerization and insecticidal activity.
Applied and Environmental Microbiology,
83 (20),
e01515-e01517.
Artículo
118 - Portugal, L., Munoz-Garay, C., Martinez-deCastro, D.L., Soberon, M., Bravo, A. (2017). Toxicity of Cry1A toxins from Bacillus thuringiensis to CF1 cells does not involve activation of adenylate cyclase/PKA signaling pathway.
Insect Biochemistry and Molecular Biology,
80,
21-31.
Artículo
119 - Rubio, V.P., Bravo, A., Olmos, J. (2017). Identification of a Bacillus thuringiensis Surface-Layer-Protein with Cytotoxic Activity against MDA-MB-231 Breast Cancer Cells.
Journal of Microbiology and Biotechnology,
27 (1),
36-42.
Artículo
120 - Xiao, Y., Dai, Q., Hu, R., Pacheco, S., Yang, Y., Liang, G., Soberon, M., Bravo, A., Liu, K., Wu, K. (2017). A Single Point Mutation Resulting in Cadherin Mis-localization Underpins Resistance against Bacillus thuringiensis Toxin in Cotton Bollworm.
Journal of Biological Chemistry,
292 (7),
2933-2943.
Artículo
121 - Zhou, Z., Liu, Y., Liang, G., Huang, Y., Bravo, A., Soberon, M., Song, F., Zhou, X., Zhang, J. (2017). Insecticidal specificity of Cry1Ah to Helicoverpa armigera is determined by binding APN1 through domain II loops 2 and 3.
Applied and Environmental Microbiology,
83 (4),
e02864-16.
Artículo
122 - Fang,L., Wang,B., Zhou,Z., Yang,S., Shu,C., Song,F., Bravo,A., Soberon,M., Zhang,J. (2016). Oligomerization of Cry9Aa in solution without receptor binding, is not related with insecticidal activity.
Electronic Journal of Biotechnology,
21,
54-57.
Artículo
123 - Jin,T., Duan,X., Bravo,A., Soberon,M., Wang,Z., He,K. (2016). Identification of an alkaline phosphatase as a putative Cry1Ac binding protein in Ostrinia furnacalis (Gun?e).
Pesticide Biochemistry And Physiology,
131,
80-86.
Artículo
124 - Queiroz,P.R., Ramiro,C.A., Martins,E.S., Soberon,M., Bravo,A., Monnerat,R.G. (2016). Mitochondrial markers to distinguish Spodoptera frugiperda populations associated with corn and cotton crops.
Pesquisa Agropecuaria Brasileira,
51 (5),
692-696.
Artículo
125 - Wang,Y., Wang,Y., Wang,Z., Bravo,A., Soberon,M., He,K. (2016). Genetic Basis of Cry1F-Resistance in a Laboratory Selected Asian Corn Borer Strain and Its Cross-Resistance to Other Bacillus thuringiensis Toxins.
PLoS ONE,
11 (8),
e0161189.
Artículo
126 - Xiao,Y., Liu,K., Zhang,D., Gong,L., He,F., Soberon,M., Bravo,A., Tabashnik,B.E., Wu,K. (2016). Resistance to Bacillus thuringiensis Mediated by an ABC Transporter Mutation Increases Susceptibility to Toxins from Other Bacteria in an Invasive Insect.
PLoS Pathogens,
12 (2),
e1005450.
Artículo
127 - Zhang,D., Xiao,Y., Hussain,Dhiloo K., Soberon,M., Bravo,A., Wu,K. (2016). Molecular Cloning, Expression, and Identification of Bre Genes Involved in Glycosphingolipids Synthesis in Helicoverpa armigera (Lepidoptera: Noctuidae).
Journal Of Economic Entomology,
109 (3),
1415-1423.
Artículo
128 - Zhou,Z., Wang,Z., Liu,Y., Liang,G., Shu,C., Song,F., Zhou,X., Bravo,A., Soberon,M., Zhang,J. (2016). Identification of ABCC2 as a binding protein of Cry1Ac on brush border membrane vesicles from Helicoverpa armigera by an improved pull-down assay.
Microbiologyopen,
5 (4),
659-669.
Artículo
129 - Canton,P.E., Cancino-Rodezno,A., Gill,S.S., Soberon,M., Bravo,A. (2015). Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis.
BMC Genomics,
16 (1),
1042.
Artículo
130 - Chavez,C., Recio-Totoro,B., Flores-Escobar,B., Lanz-Mendoza,H., Sanchez,J., Soberon,M., Bravo,A. (2015). Nitric oxide participates in the toxicity of Bacillus thuringiensis Cry1Ab toxin to kill Manduca sexta larvae.
Peptides,
68,
134-139.
Artículo
131 - Garcia,K., Ibarra,J.E., Bravo,A., Diaz,J., Gutierrez,D., Torres,P.V., Gomez de Leon P. (2015). Variability of Bacillus thuringiensis Strains by ERIC-PCR and Biofilm Formation.
Current Microbiology,
70 (1),
10-18.
Artículo
Artículo
133 - Monnerat,R., Martins,E., Macedo,C., Queiroz,P., Praca,L., Soares,C.M., Moreira,H., Grisi,I., Silva,J., Soberon,M., Bravo,A. (2015). Evidence of Field-Evolved Resistance of Spodoptera frugiperda to Bt Corn Expressing Cry1F in Brazil That Is Still Sensitive to Modified Bt Toxins.
PLoS ONE,
10 (4),
e0119544.
Artículo
134 - Ocelotl,J., Sanchez,J., Arroyo,R., Garcia-Gomez,B.I., Gomez,I., Unnithan,G.C., Tabashnik,B.E., Bravo,A., Soberon,M. (2015). Binding and Oligomerization of Modified and Native Bt Toxins in Resistant and Susceptible Pink Bollworm.
PLoS ONE,
10 (12),
e0144086.
Artículo
135 - Pacheco,S., Canton,E., Zuniga-Navarrete,F., Pecorari,F., Bravo,A., Soberon,M. (2015). Improvement and efficient display of Bacillus thuringiensis toxins on M13 phages and ribosomes.
AMB Express,
5 (1),
73.
Artículo
136 - Shu,C., Tan,S., Yin,J., Soberon,M., Bravo,A., Liu,C., Geng,L., Song,F., Li,K., Zhang,J. (2015). Assembling of Holotrichia parallela (dark black chafer) midgut tissue transcriptome and identification of midgut proteins that bind to Cry8Ea toxin from Bacillus thuringiensis.
Applied Microbiology and Biotechnology,
99 (17),
7209-7218.
Artículo
137 - Tabashnik,B.E., Zhang,M., Fabrick,J.A., Wu,Y., Gao,M., Huang,F., Wei,J., Zhang,J., Yelich,A., Unnithan,G.C., Bravo,A., Soberon,M., Carriere,Y., Li,X. (2015). Dual mode of action of Bt proteins: protoxin efficacy against resistant insects.
Scientific Reports,
5,
15107.
Artículo
138 - Zuniga-Navarrete,F., Gomez,I., Pena,G., Amaro,I., Ortiz,E., Becerril,B., Ibarra,J.E., Bravo,A., Soberon,M. (2015). Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12.
Insect Biochemistry and Molecular Biology,
59,
50-57.
Artículo
139 - Canton,P.E., Lopez-Diaz,J.A., Gill,S.S., Bravo,A., Soberon,M. (2014). Membrane binding and oligomer membrane insertion are necessary but insufficient for Bacillus thuringiensis Cyt1Aa toxicity.
Peptides,
53,
286-291.
Artículo
140 - Gomez,I., Sanchez,J., Munoz-Garay,C., Matus,V., Gill,S.S., Soberon,M., Bravo,A. (2014). Bacillus thuringiensis Cry1A toxins are versatile-proteins with multiple modes of action: two distinct pre-pores are involved in toxicity.
Biochemical Journal,
459 (2),
383-396.
Artículo
141 - Monnerat,R., Pereira,E., Teles,B., Martins,E., Praca,L., Queiroz,P., Soberon,M., Bravo,A., Ramos,F., Soares,C.M. (2014). Synergistic activity of Bacillus thuringiensis toxins against Simulium spp. larvae.
Journal of Invertebrate Pathology,
121,
70-73.
Artículo
142 - Portugal,L., Gringorten,J.L., Caputo,G.F., Soberon,M., Munoz-Garay,C., Bravo,A. (2014). Toxicity and mode of action of insecticidal Cry1A proteins from Bacillus thuringiensis in an insect cell line, CF-1.
Peptides,
53,
292-299.
Artículo
143 - Bedoya-Perez,L.P., Cancino-Rodezno,A., Flores-Escobar,B., Soberon,M., Bravo,A. (2013). Role of UPR Pathway in Defense Response of Aedes aegypti against Cry11Aa Toxin from Bacillus thuringiensis.
International Journal of Molecular Sciences,
14 (4),
8467-8478.
Artículo
144 - Bravo,A. (2013). Biotecnología agrícola y agroecologia, complementarias u opuestas?.
Ciencia, Revista de la Academia Mexicana de Ciencia,
64 (1),
68-77.
Revisión
145 - Bravo,A., Gomez,I., Porta,H., Garcia-Gomez,B.I., Rodriguez-Almazan,C., Pardo,L., Soberon,M. (2013). Evolution of Bacillus thuringiensis Cry toxins insecticidal activity.
Microbial Biotechnology,
6 (1),
17-26.
Artículo
146 - Flores-Escobar,B., Rodriguez-Magadan,H., Bravo,A., Soberon,M., Gomez,I. (2013). Differential role of Manduca sexta aminopeptidase-N and alkaline phosphatase in the mode of action of Cry1Aa, Cry1Ab, and Cry1Ac toxins from Bacillus thuringiensis.
Applied and Environmental Microbiology,
79 (15),
4543-4550.
Artículo
147 - Garcia-Gomez,B.I., Sanchez,J., Martinez de Castro,D.L., Ibarra,J.E., Bravo,A., Soberon,M. (2013). Efficient production of Bacillus thuringiensis Cry1AMod toxins under regulation of cry3Aa promoter and single cysteine mutations in the protoxin region.
Applied and Environmental Microbiology,
79 (22),
6969-6973.
Artículo
148 - Lopez-Diaz,J.A., Canton,P.E., Gill,S.S., Soberon,M., Bravo,A. (2013). Oligomerization is a key step in Cyt1Aa membrane insertion and toxicity but not necessary to synergize Cry11Aa toxicity in Aedes aegypti larvae.
Environmental Microbiology,
15 (11),
3030-3039.
Revisión
149 - Pardo-Lopez,L., Soberon,M., Bravo,A. (2013). Bacillus thuringiensis insecticidal 3-domain Cry toxins: Mode of action, insect resistance and consequences for crop protection.
FEMS Microbiology Reviews,
37 (1),
3-22.
Revisión
150 - Soberon,M., Lopez-Diaz,J.A., Bravo,A. (2013). Cyt toxins produced by Bacillus thuringiensis: A protein fold conserved in several pathogenic microorganisms.
Peptides,
41,
87-93.
Artículo
151 - Tabashnik,B.E., Fabrick,J.A., Unnithan,G.C., Yelich,A.J., Masson,L., Zhang,J., Bravo,A., Soberon,M. (2013). Efficacy of Genetically Modified Bt Toxins Alone and in Combinations Against Pink Bollworm Resistant to Cry1Ac and Cry2Ab.
PLoS ONE,
8 (11),
e80496.
Artículo; Actas Paper
152 - Zuniga-Navarrete,F., Gomez,I., Pena,G., Bravo,A., Soberon,M. (2013). A Tenebrio molitor GPI-anchored alkaline phosphatase is involved in binding of Bacillus thuringiensis Cry3Aa to brush border membrane vesicles.
Peptides,
41,
81-86.
Artículo
153 - Cancino-Rodezno,A., Lozano,L., Oppert,C., Castro,J.I., Lanz-Mendoza,H., Encarnacion,S., Evans,A.E., Gill,S.S., Soberon,M., Jurat-Fuentes,J.L., Bravo,A. (2012). Comparative Proteomic Analysis of Aedes aegypti Larval Midgut after Intoxication with Cry11Aa Toxin from Bacillus thuringiensis.
PLoS ONE,
7 (5),
e37034.
Artículo
154 - Jimenez,A.I., Reyes,E.Z., Cancino-Rodezno,A., Bedoya-Perez,L.P., Caballero-Flores,G.G., Muriel-Millan,L.F., Likitvivatanavong,S., Gill,S.S., Bravo,A., Soberon,M. (2012). Aedes aegypti alkaline phosphatase ALP1 is a functional receptor of Bacillus thuringiensis Cry4Ba and Cry11Aa toxins.
Insect Biochemistry and Molecular Biology,
42 (9),
683-689.
Artículo
155 - Rodriguez-Almazan,C., Reyes,E.Z., Zuniga-Navarrete,F., Munoz-Garay,C., Gomez,I., Evans,A.M., Likitvivatanavong,S., Bravo,A., Gill,S.S., Soberon,M. (2012). Cadherin binding is not a limiting step for Bacillus thuringiensis subs. israelensis Cry4Ba toxicity to Aedes aegypti larvae.
Biochemical Journal,
443,
711-717.
Artículo
156 - Soberon,M., Rodriguez-Almazan,C., Munoz-Garay,C., Pardo-Lopez,L., Porta,H., Bravo,A. (2012). Bacillus thuringiensis Cry and Cyt mutants useful to counter toxin action in specific environments and to overcome insect resistance in the field.
Pesticide Biochemistry And Physiology,
104 (2),
111-117.
Revisión
157 - Vazquez-Pineda,A., Bravo-de-la-Parra,A., Mendoza de Gives,P., Liebano-Hernandez,E., Hernandez-Linares,I, Yanez-Perez,N., Aguilar-Marcelino,L., Ramirez-Vargas,G., Hernandez-Castro,E., Gutierrez-Segura,I., Lopez-Arellano,E. (2012). Use of Bacillus thuringiensis products as alternative method of control against important veterinary parasitic nematodes : Review.
Revista Mexicana de Ciencias Pecuarias,
3 (1),
77-88.
Revisión
158 - Bravo,A., Likitvivatanavong,S., Gill,S.S., Soberon,M. (2011). Bacillus thuringiensis: A story of a successful bioinsecticide.
Insect Biochemistry and Molecular Biology,
41 (7),
423-431.
Artículo
159 - Canton,P.E., Reyes,E.Z., Escudero,I.R., Bravo,A., Soberon,M. (2011). Binding of Bacillus thuringiensis subsp. israelensis Cry4Ba to Cyt1Aa has an important role in synergism.
Peptides,
32 (3),
595-600.
Artículo
160 - Carmona,D., Rodriguez-Almazan,C., Munoz-Garay,C., Portugal,L., Perez,C., de Maagd,R.A., Bakker,P., Soberon,M., Bravo,A. (2011). Dominant Negative Phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba Mutants Suggest Hetero-Oligomer Formation among Different Cry Toxins.
PLoS ONE,
6 (5),
e19952.
Artículo
161 - Likitvivatanavong,S., Chen,J., Evans,A.M., Bravo,A., Soberon,M., Gill,S.S. (2011). Multiple Receptors as Targets of Cry Toxins in Mosquitoes.
Journal of Agricultural and Food Chemistry,
59 (7),
2829-2838.
Artículo
162 - Likitvivatanavong,S., Chen,J., Bravo,A., Soberon,M., Gill,S.S. (2011). Cadherin, Alkaline Phosphatase, and Aminopeptidase N as Receptors of Cry11Ba Toxin from Bacillus thuringiensis subsp. jegathesan in Aedes aegypti?.
Applied and Environmental Microbiology,
77 (1),
24-31.
Artículo
163 - Porta,H., Munoz-Minutti,C., Soberon,M., Bravo,A. (2011). Induction of Manduca sexta Larvae Caspases Expression in Midgut Cells by Bacillus thuringiensis Cry1Ab Toxin.
Psyche: A Journal of Entomology,
Article ID 938249.
Artículo
164 - Porta,H., Jimenez,G., Cordoba,E., Leon,P., Soberon,M., Bravo,A. (2011). Tobacco plants expressing the Cry1AbMod toxin suppress tolerance to Cry1Ab toxin of Manduca sexta cadherin-silenced larvae.
Insect Biochemistry and Molecular Biology,
41 (7),
513-519.
Revisión
165 - Porta,H., Cancino-Rodezno,A., Soberon,M., Bravo,A. (2011). Role of MAPK p38 in the cellular responses to pore-forming toxins.
Peptides,
32 (3),
601-606.
Artículo
166 - Rodriguez-Almazan,C., Ruiz de Escudero,I, Canton,P.E., Munoz-Garay,C., Perez,C., Gill,S.S., Soberon,M., Bravo,A. (2011). The amino- and carboxyl-terminal fragments of the Bacillus thuringiensis Cyt1Aa toxin have differential roles on toxin oligomerization and pore formation.
Biochemistry,
50 (3),
388-396.
Artículo
167 - Tabashnik,B.E., Huang,F., Ghimire,M.N., Leonard,B.R., Siegfried,B.D., Rangasamy,M., Yang,Y., Wu,Y., Gahan,L.J., Heckel,D.G., Bravo,A., Soberon,M. (2011). Efficacy of genetically modified Bt toxins against insects with different genetic mechanisms of resistance.
Nature Biotechnology,
29,
1128-1131.
Revisión
168 - Terenius,O., Papanicolaou,A., Garbutt,J.S., Eleftherianos,I., Huvenne,H., Sriramana,K., Albrechtsen,M., An,C., Aymeric,J.L., Barthel,A., Bebas,P., Bitra,K., Bravo,A., Chevalier,F., Collinge,D.P., Crava,C.M., de Maagd,R.A., Duvic,B., Erlandson,M., Faye,I., Felfoldi,G., Fujiwara,H., Futahashi,R., Gandhe,A.S., Gatehouse,H.S., Gatehouse,L.N., Giebultowicz,J., Gomez,I., Grimmelikhuijzen,C.J., Groot,A.T., Hauser,F., Heckel,D.G., Hegedus,D.D., Hrycaj,S., Huang,L., Hull,J.J., Iatrou,K., Iga,M., Kanost,M.R., Kotwica,J., Li,C., Li,J., Liu,J., Lundmark,M., Matsumoto,S., Meyering-Vos,M., Millichap,P.J., Monteiro,A., Mrinal,N., Niimi,T., Nowara,D., Ohnishi,A., Oostra,V., Ozaki,K., Papakonstantinou,M., Popadic,A., Rajam,M.V., Saenko,S., Simpson,R.M., Soberon,M., Strand,M.R., Tomita,S., Toprak,U., Wang,P., Wee,C.W., Whyard,S., Zhang,W., Nagaraju,J., Ffrench-Constant,R.H., Herrero,S., Gordon,K., Swevers,L., Smagghe,G., et al (2011). RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design.
Journal of Insect Physiology,
57 (2),
231-245.
Artículo
169 - Zavala,L.E., Pardo-Lopez,L., Canton,P.E., Gomez,I., Soberon,M., Bravo,A. (2011). Domains II and III of Bacillus thuringiensis Cry1Ab toxin remain exposed to the solvent after insertion of part of domain I into the membrane.
Journal of Biological Chemistry,
286 (21),
19109-19117.
Artículo
170 - Arenas,I., Bravo,A., Soberon,M., Gomez,I. (2010). Role of alkaline phosphatase from Manduca sexta in the mechanism of action of Bacillus thuringiensis Cry1Ab toxin.
Journal of Biological Chemistry,
285 (17),
12497-503.
Artículo
171 - Cancino-Rodezno,A., Alexander,C., Villasenor,R., Pacheco,S., Porta,H., Pauchet,Y., Soberon,M., Gill,S.S., Bravo,A. (2010). The mitogen-activated protein kinase p38 is involved in insect defense against cry toxins from Bacillus thuringiensis.
Insect Biochemistry and Molecular Biology,
40 (1),
58-63 [corrigendum 43 (9) 898 2013 ].
Artículo
172 - Fernandez-Luna,M.T., Tabashnik,B.E., Lanz-Mendoza,H., Bravo,A., Soberon,M., Miranda-Rios,J. (2010). Single concentration tests show synergism among Bacillus thuringiensis subsp. israelensis toxins against the malaria vector mosquito Anophelesalbimanus.
Journal of Invertebrate Pathology,
104 (3),
231-233.
Artículo
173 - Fernandez-Luna,M.T., Lanz-Mendoza,H., Gill,S.S., Bravo,A., Soberon,M., Miranda-Rios,J. (2010). An alpha-amylase is a novel receptor for Bacillus thuringiensis ssp. israelensis Cry4Ba and Cry11Aa toxins in the malaria vector mosquito Anopheles albimanus (Diptera: Culicidae).
Environmental Microbiology,
12 (3),
746-757.
Artículo
174 - Fernandez-Ruvalcaba,M., Pena-Chora,G., Romo-Martinez,A., Hernandez-Velazquez,V., de la Parra,A.B., De la Rosa,D.P. (2010). Evaluation of Bacillus thuringiensis pathogenicity for a strain of the tick, Rhipicephalus microplus, resistant to chemical pesticides - art. no. 186.
Journal of Insect Science,
10,
186-190.
Artículo
175 - Gomez,I., Arenas,I., Pacheco,S., Bravo,A., Soberon,M. (2010). New Insights into the Mode of Action of Cry1Ab Toxin Used in Transgenic Insect-resistant Crops.
Southwestern Entomologist,
35 (3),
387-390.
Artículo
176 - Martins,E.S., Monnerat,R.G., Queiroz,P.R., Dumas,V.F., Braz,S.V., de Souza Aguiar,R.W., Mendes-Gomes,A.C., Sanchez,J., Bravo,A., Ribeiro,B.M. (2010). Midgut GPI- anchored proteins with alkaline phosphatase activity from the cotton boll weevil (Anthonomus grandis) can be the putative receptors for the Cry1B protein of Bacillus thuringiensis.
Insect Biochemistry and Molecular Biology,
40 (2),
138-145.
Artículo
177 - Munoz-Garay,C., Soberon,M., Bravo,A. (2010). Mode of Action of Bacillus thuringiensis-Genetically Modified Cry1AbMod and Cry1AcMod Toxins Role of Alkaline pH in Toxin Oligomerization.
Southwestern Entomologist,
35 (3),
383-386.
Artículo; Actas Paper
178 - Vazquez-Pineda,A., Yanez-Perez,G.N., Lopez-Arellano,M.E., Mendoza de Gives,P., Liebano-Hernandez,E., Bravo-de-la-Parra,A. (2010). Biochemical Characterization of Two Purified Proteins of the IB-16 Bacillus thuringiensis Strains and Their Toxicity Against the Sheep Nematode Haemonchus contortus In vitro.
Transboundary and Emerging Diseases,
57 (1-2),
111-114.
Revisión
179 - Cancino-Rodezno,A., Porta,H., Soberon,M., Bravo,A. (2009). Defense and death responses to pore forming toxins.
Biotechnology and Genetic Engineering Reviews,
26 (65),
82.
Artículo
180 - Chen,J., Aimanova,K.G., Fernandez,L.E., Bravo,A., Soberon,M., Gill,S.S. (2009). Aedes aegypti cadherin serves as a putative receptor of the Cry11Aa toxin from Bacillus thuringiensis subsp. israelensis.
Biochemical Journal,
424 (2),
191-200.
Artículo
181 - Fernandez,L.E., Martinez-Anaya,C., Lira,E., Chen,J., Evans,A., Hernandez-Martinez,S., Lanz-Mendoza,H., Bravo,A., Gill,S.S., Soberon,M. (2009). Cloning and epitope mapping of Cry11Aa-binding sites in the Cry11Aa-receptor alkaline phosphatase from Aedes aegypti.
Biochemistry,
48 (37),
8899-8907.
Artículo
182 - Franklin,M.T., Nieman,C.L., Janmaat,A.F., Soberon,M., Bravo,A., Tabashnik,B.E., Myers,J.H. (2009). Modified Bacillus thuringiensis toxins and a hybrid B. thuringiensis strain counter greenhouse-selected resistance in Trichoplusia ni.
Applied and Environmental Microbiology,
75 (17),
5739-5741.
Artículo
183 - Munoz-Garay,C., Portugal,L., Pardo-Lopez,L., Jimenez-Juarez,N., Arenas,I., Gomez,I., Sanchez-Lopez,R., Arroyo,R., Holzenburg,A., Savva,C.G., Soberon,M., Bravo,A. (2009). Characterization of the mechanism of action of the genetically modified Cry1AbMod toxin that is active against Cry1Ab-resistant insects.
Biochimica et Biophysica Acta (BBA) - Biomembranes,
1788 (10),
2229-2237.
Artículo
184 - Munoz-Garay,C., Rodriguez-Almazan,C., Aguilar,J.N., Portugal,L., Gomez,I., Saab-Rincon,G., Soberon,M., Bravo,A. (2009). Oligomerization of Cry11Aa from Bacillus thuringiensis has an important role in toxicity against Aedes aegypti.
Applied and Environmental Microbiology,
75 (23),
7548-7550.
Artículo
185 - Pacheco,S., Gomez,I., Gill,S.S., Bravo,A., Soberon,M. (2009). Enhancement of insecticidal activity of Bacillus thuringiensis Cry1A toxins by fragments of a toxin-binding cadherin correlates with oligomer formation.
Peptides,
30 (3),
583-588.
Artículo
186 - Pacheco,S., Gomez,I., Arenas,I., Saab-Rincon,G., Rodriguez-Almazan,C., Gill,S.S., Bravo,A., Soberon,M. (2009). Domain II loop 3 of Bacillus thuringiensis Cry1Ab toxin is involved in a "ping-pong" binding mechanism with Manduca sexta aminopetidase-N and cadherin receptors.
Journal of Biological Chemistry,
284 (47),
32750-32757.
Revisión
187 - Pardo-Lopez,L., Munoz-Garay,C., Porta,H., Rodriguez-Almazan,C., Soberon,M., Bravo,A. (2009). Strategies to improve the insecticidal activity of Cry toxins from Bacillus thuringiensis.
Peptides,
30 (3),
589-595.
Artículo
188 - Rodriguez-Almazan,C., Zavala,L.E., Munoz-Garay,C., Jimenez-Juarez,N., Pacheco,S., Masson,L., Soberon,M., Bravo,A. (2009). Dominant negative mutants of Bacillus thuringiensis Cry1Ab toxin function as anti-toxins: demonstration of the role of oligomerization in toxicity.
PLoS ONE,
4 (5),
e5545 [Erratum 2013 8 (2)].
Revisión
189 - Soberon,M., Gill,S.S., Bravo,A. (2009). Signaling versus punching hole: How do Bacillus thuringiensis toxins kill insect midgut cells?.
Cellular and Molecular Life Sciences,
66 (8),
1337-1349.
Revisión
190 - Bravo,A., Soberon,M. (2008). How to cope with insect resistance to Bt toxins?.
Trends in Biotechnology,
26 (10),
573-579.
Artículo
191 - Fernandez,L.E., Gomez,I., Pacheco,S., Arenas,I., Gill,S.S., Bravo,A., Soberon,M. (2008). Employing phage display to study the mode of action of Bacillus thuringiensis Cry toxins.
Peptides,
29 (2),
324-329.
Artículo
192 - Hernandez-Linares,I, Lopez-Arellano,M.E., Mendoza de Gives,P., Liebano-Hernandez,E., Bravo-de-la-Parra,A. (2008). Lethal activity of two Bacillus thuringiensis strains against Haemonchus contortus histotropic larvae.
Annals of the New York Academy of Sciences,
1149,
164-166.
Artículo
193 - Jimenez-Juarez,N., Munoz-Garay,C., Gomez,I., Gill,S.S., Soberon,M., Bravo,A. (2008). The pre-pore from Bacillus thuringiensis Cry1Ab toxin is necessary to induce insect death in Manduca sexta.
Peptides,
29 (2),
318-323.
Revisión
194 - Bravo,A., Gill,S.S., Soberon,M. (2007). Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control.
Toxicon,
49 (4),
423-435.
Artículo; Actas Paper
195 - Gomez,I., Pardo-Lopez,L., Munoz-Garay,C., Fernandez,L.E., Perez,C., Sanchez,J., Soberon,M., Bravo,A. (2007). Role of receptor interaction in the mode of action of insecticidal Cry and Cyt toxins produced by Bacillus thuringiensis.
Peptides,
28 (1),
169-173.
Artículo
196 - Ishikawa,H., Hoshino,Y., Motoki,Y., Kawahara,T., Kitajima,M., Kitami,M., Watanabe,A., Bravo,A., Soberon,M., Honda,A., Yaoi,K., Sato,R. (2007). A system for the directed evolution of the insecticidal protein from Bacillus thuringiensis.
Molecular Biotechnology,
36 (2),
90-101.
Artículo
197 - Jimenez-Juarez,N., Munoz-Garay,C., Gomez,I., Saab-Rincon,G., Damian-Almazo,J.Y., Gill,S.S., Soberon,M., Bravo,A. (2007). Bacillus thuringiensis Cry1Ab mutants affecting oligomer formation are non toxic to Manduca sexta larvae.
Journal of Biological Chemistry,
282 (29),
21222-21229.
Artículo
198 - Ochoa-Campuzano,C., Real,M.D., Martinez-Ramirez,A.C., Bravo,A., Rausell,C. (2007). An ADAM metalloprotease is a Cry3Aa Bacillus thuringiensis toxin receptor.
Biochemical and Biophysical Research Communications,
362 (2),
437-442.
Artículo
199 - Perez,C., Munoz-Garay,C., Portugal,L.C., Sanchez,J., Gill,S.S., Soberon,M., Bravo,A. (2007). Bacillus thuringiensis ssp. israelensis Cyt1Aa enhances activity of Cry11Aa toxin by facilitating the formation of a pre-pore oligomeric structure.
Cellular Microbiology,
9 (12),
2931-2937.
Artículo
200 - Rausell,C., Ochoa-Campuzano,C., Martinez-Ramirez,A.C., Bravo,A., Real,M.D. (2007). A membrane associated metalloprotease cleaves Cry3Aa Bacillus thuringiensis toxin reducing pore formation in Colorado potato beetle brush border membrane vesicles.
Biochimica et Biophysica Acta (BBA) - Biomembranes,
362 (2),
437-442.
Artículo
201 - Sauka,D.H., Sanchez,J., Bravo,A., Benintende,G.B. (2007). Toxicity of Bacillus thuringiensis delta-endotoxins against bean shoot borer (Epinotia aporema Wals.) larvae, a major soybean pest in Argentina.
Journal of Invertebrate Pathology,
94 (2),
125-129.
Artículo
202 - Soberon,M., Pardo-Lopez,L., Lopez,I., Gomez,I., Tabashnik,B.E., Bravo,A. (2007). Engineering Modified Bt Toxins to Counter Insect Resistance.
Science,
318 (5856),
1640-1642 [erratum vol 345 (6198) art num 1256132].
Revisión
203 - Soberon,M., Fernandez,L.E., Perez,C., Gill,S.S., Bravo,A. (2007). Mode of action of mosquitocidal Bacillus thuringiensis toxins.
Toxicon,
49 (5),
597-600.
Artículo
204 - Fernandez,L.E., Aimanova,K.G., Gill,S.S., Bravo,A., Soberon,M. (2006). A GPI-anchored alkaline phosphatase is a functional midgut receptor of Cry11Aa toxin in Aedes aegypti larvae.
Biochemical Journal,
394 (1),
77-84.
Artículo
205 - Gomez,I., Arenas,I., Benitez,I., Miranda-Rios,J., Becerril,B., Grande,R., Almagro,J.C., Bravo,A., Soberon,M. (2006). Specific epitopes of domains II and IIII of bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in manduca sexta.
Journal of Biological Chemistry,
281 (45),
34032-34039.
Artículo; Actas Paper
206 - Lopez,M.E., Flores,J., Mendoza,P., Vazquez,V., Liebano,E., Bravo,A., Herrera,D., Godines,E., Vargas,P., Zamudio,F. (2006). Use of Bacillus thuringiensis Toxin as an Alternative Method of Control against Haemonchus contortus.
Annals of the New York Academy of Sciences,
1081,
347-354.
Artículo
207 - Monnerat,R., Martins,E., Queiroz,P., Orduz,S., Jaramillo,G., Benintende,G., Cozzi,J., Real,M.D., Martinez-Ramirez,A., Rausell,C., Ceron,J., Ibarra,J.E., Del Rincon-Castro,M.C., Espinoza,A.M., Meza-Basso,L., Cabrera,L., Sanchez,J., Soberon,M., Bravo,A. (2006). Genetic variability of Spodoptera frugiperda Smith (Lepidoptera: Noctuidae) populations from Latin America is associated with variations in susceptibility to Bacillus thuringiensis Cry toxins.
Applied and Environmental Microbiology,
72 (11),
7029-7035.
Artículo
208 - Munoz-Garay,C., Sanchez,J., Darszon,A., de Maagd,R.A., Bakker,P., Soberon,M., Bravo,A. (2006). Permeability Changes of Manduca sexta Midgut Brush Border Membranes Induced by Oligomeric Structures of Different Cry Toxins.
Journal of Membrane Biology,
212 (1),
61-68 [Erratum: 245 (12) 859].
Artículo
209 - Pacheco,S., Gomez,I., Sato,R., Bravo,A., Soberon,M. (2006). Functional display of Bacillus thuringiensis Cry1Ac toxin on T7 phage.
Journal of Invertebrate Pathology,
92 (1),
45-49.
Artículo
210 - Padilla,C., Pardo-Lopez,L., de la Riva,G., Gomez,I., Sanchez,J., Hernandez,G., Nunez,M.E., Carey,M.P., Dean,D.H., Alzate,O., Soberon,M., Bravo,A. (2006). Role of Tryptophan Residues in Toxicity of Cry1Ab Toxin from Bacillus thuringiensis.
Applied and Environmental Microbiology,
72 (1),
901-907.
Artículo; Actas Paper
211 - Pardo-Lopez,L., Gomez,I., Munoz-Garay,C., Jimenez-Juarez,N., Soberon,M., Bravo,A. (2006). Structural and functional analysis of the pre-pore and membrane-inserted pore of Cry1Ab toxin.
Journal of Invertebrate Pathology,
92 (3),
172-177.
Artículo
212 - Pardo-Lopez,L., Gomez,I., Rausell,C., Sanchez,J., Soberon,M., Bravo,A. (2006). Structural Changes of the Cry1Ac Oligomeric Pre-Pore from Bacillus thuringiensis Induced by N-Acetylgalactosamine Facilitates Toxin Membrane Insertion.
Biochemistry,
45 (34),
10329-10336.
Artículo
213 - Pena,G., Miranda-Rios,J., de la Riva,G., Pardo-Lopez,L., Soberon,M., Bravo,A. (2006). A Bacillus thuringiensis S-Layer Protein Involved in Toxicity against Epilachna varivestis (Coleoptera: Coccinellidae).
Applied and Environmental Microbiology,
72 (1),
353-360.
Carta
214 - de Maagd,R.A., Bravo,A., Crickmore,N. (2005). Bt toxin not guilty by association.
Nature Biotechnology,
23 (7),
791.
Artículo
215 - Fernandez,L.E., Perez,C., Segovia,L., Rodriguez,M.H., Gill,S.S., Bravo,A., Soberon,M. (2005). Cry11Aa toxin from Bacillus thuringiensis binds its receptor in Aedes aegypti mosquito larvae through loop alpha-8 of domain II.
FEBS Letters,
579 (17),
3508-3514.
Artículo
216 - Letowski,J., Bravo,A., Brousseau,R., Masson,L. (2005). Assessment of cry1 Gene Contents of Bacillus thuringiensis Strains by Use of DNA Microarrays.
Applied and Environmental Microbiology,
71 (9),
5391-5398.
Artículo
217 - Perez,C., Fernandez,L.E., Sun,J., Folch,J.L., Gill,S.S., Soberon,M., Bravo,A. (2005). Bacillus thuringiensis subsp. israelensis Cyt1Aa synergizes Cry11Aa toxin by functioning as a membrane-bound receptor.
Proceedings of the National Academy of Sciences of the United States of America,
102 (51),
18303-18308.
Artículo
218 - Xie,R., Zhuang,M., Ross,L.S., Gomez,I., Oltean,D.I., Bravo,A., Soberon,M., Gill,S.S. (2005). Single amino acid mutations in the cadherin receptor from heliothis virescens affect its toxin binding ability to Cry1A toxins.
Journal of Biological Chemistry,
280 (9),
8416-8425.
Artículo
219 - Bravo,A., Gomez,I., Conde,J., Munoz-Garay,C., Sanchez,J., Miranda,R., Zhuang,M., Gill,S.S., Soberon,M. (2004). Oligomerization triggers binding of a Bacillus thuringiensis Cry1Ab pore-forming toxin to aminopeptidase N receptor leading to insertion into membrane microdomains.
Biochimica et Biophysica Acta (BBA) - Biomembranes,
1667 (1),
38-46.
Artículo
220 - da Silva,S.M.B., Silva-Werneck,J.O., Falcao,R., Gomes,A.C., Fragoso,R.R., Quezado,M.T., Neto,O.B.O., Aguiar,J.B., de Sa,M.F.G., Bravo,A., Monnerat,R.G. (2004). Characterization of novel Brazilian Bacillus thuringiensis strains active against Spodoptera frugiperda and other insect pests.
Journal of Applied Entomology,
128 (2),
102-107.
Artículo
221 - Rausell,C., Pardo-Lopez,L., Sanchez,J., Munoz-Garay,C., Morera,C., Soberon,M., Bravo,A. (2004). Unfolding events in the water-soluble monomeric Cry1Ab toxin during transition to oligomeric pre-pore and to membrane inserted pore channel.
Journal of Biological Chemistry,
279 (53),
55168-55175.
Artículo
222 - Rausell,C., Munoz-Garay,C., Miranda-CassoLuengo,R., Gomez,I., Rudino-Pinera,E., Soberon,M., Bravo,A. (2004). Tryptophan Spectroscopy Studies and Black Lipid Bilayer Analysis Indicate that the Oligomeric Structure of Cry1Ab Toxin from Bacillus thuringiensis Is the Membrane-Insertion Intermediate.
Biochemistry,
43 (1),
166-174.
Artículo
223 - Rausell,C., Garcia-Robles,I., Sanchez,J., Munoz-Garay,C., Martinez-Ramirez,A.C., Real,M.D., Bravo,A. (2004). Role of toxin activation on binding and pore formation activity of the Bacillus thuringiensis Cry3 toxins in membranes of Leptinotarsa decemlineata (Say).
Biochimica et Biophysica Acta (BBA) - Biomembranes,
1660 (1-2),
99-105.
Artículo
224 - Vazquez-Padron,R.I., de la Riva,G., Silva,Y., Pham,S.M., Soberon,M., Bravo,A., Aitouche,A. (2004). Cryptic endotoxic nature of Bacillus thuringiensis Cry1Ab insecticidal crystal protein.
FEBS Letters,
570 (1-3),
30-36.
Revisión
225 - de Maagd,R.A., Bravo,A., Berry,C., Crickmore,N., Schnepf,H.E. (2003). Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria.
Annual Review of Genetics,
37,
409-433.
Artículo
226 - Gomez,I., Dean,D.H., Bravo,A., Soberon,M. (2003). Molecular Basis for Bacillus thuringiensis Cry1Ab Toxin Specificity: Two Structural Determinants in the Manduca sexta Bt-R(1) Receptor Interact with Loops alpha-8 and 2 in Domain II of Cy1Ab Toxin.
Biochemistry,
42 (35),
10482-10489.
Artículo
227 - Ibarra,J.E., Del Rincon,M.C., Orduz,S., Noriega,D., Benintende,G., Monnerat,R., Regis,L., De Oliveira,C.M., Lanz,H., Rodriguez,M.H., Sanchez,J., Pena,G., Bravo,A. (2003). Diversity of Bacillus thuringiensis Strains from Latin America with Insecticidal Activity against Different Mosquito Species.
Applied and Environmental Microbiology,
69 (9),
5269-5274.
Artículo
228 - Bravo,A., Sanchez,J., Kouskoura,T., Crickmore,N. (2002). N-terminal activation is an essential early step in the mechanism of action of the B. thuringiensis Cry1Ac insecticidal toxin.
Journal of Biological Chemistry,
277 (27),
23985-23987.
Artículo
Artículo
230 - Gomez,I., Sanchez,J., Miranda,R., Bravo,A., Soberon,M. (2002). Cadherin-like receptor binding facilitates proteolytic cleavage of helix alpha-1 in domain I and oligomer pre-pore formation of Bacillus thuringiensis Cry1Ab toxin.
FEBS Letters,
513 (2-3),
242-246.
Artículo
231 - Gomez,I., Miranda-Rios,J., Rudino-Pinera,E., Oltean,D.I., Gill,S.S., Bravo,A., Soberon,M. (2002). Hydropathic complementarity determines interaction of epitope 869HITDTNNK876 in Manduca sexta Bt-R1 receptor with loop 2 of domain II of Bacillus thuringiensis Cry1A toxins.
Journal of Biological Chemistry,
277 (33),
30137-30143.
Artículo
232 - Lopez-Arellano,M.E., Flores-Crespo,J., Mendoza de Gives,P., Bravo-de-la-Parra,A., Herrera-Rodriguez,D, Liebano-Hernandez,E., Vazquez-Prats,V.M., Vargas-Uriostegui,P. (2002). In vitro lethal activity of Bacillus thuringiensis toxins against Haemonchus contortus eggs and infective larvae.
International Journal of Nematology,
12 (1),
66-72.
Artículo
233 - Miranda,R., Gomez,I., Soberon,M., Bravo,A. (2002). Mecanismo de accion de las toxinas Cry de Bacillus Thuringiensis.
TIP revista especializada en Ciencias Quimico-Biologicas,
5,
5-13.
Artículo
234 - Zhuang,M., Oltean,D.I., Gomez,I., Pullikuth,A.K., Soberon,M., Bravo,A., Gill,S.S. (2002). Heliothis virescens and Manduca sexta lipid rafts are involved in Cry1A toxin binding to the midgut epithelium and subsequent pore formation.
Journal of Biological Chemistry,
277 (16),
13863-13872.
Revisión
235 - de Maagd,R.A., Bravo,A., Crickmore,N. (2001). How Bacillus thuringiensis has evolved specific toxins to colonize the insect world.
Trends in Genetics,
17 (4),
193-199.
Artículo
236 - Garcia-Robles,I., Sanchez,J., Gruppe,A., Martinez-Ramirez,A.C., Rausell,C., Real,M.D., Bravo,A. (2001). Mode of action of Bacillus thuringiensis PS86Q3 strain in hymenopteran forest pests.
Insect Biochemistry and Molecular Biology,
31 (9),
849-856.
Artículo
237 - Gomez,I., Oltean,D.I., Gill,S., Bravo,A., Soberon,M. (2001). Mapping the epitope in cadherin-like receptors involved in Bacillus thuringiensis Cry1A toxins interaction using phage display.
Journal of Biological Chemistry,
276 (31),
28906-28912.
Artículo
238 - Miranda,R., Zamudio,F.Z., Bravo,A. (2001). Processing of Cry1Ab delta-endotoxin from Bacillus thuringiensis by Manduca sexta and Spodoptera frugiperda midgut proteases: role in protoxin activation and toxin inactivation.
Insect Biochemistry and Molecular Biology,
31 (12),
1155-1163.
Artículo
239 - Nunez-Valdez,M., Sanchez,J., Lina,L., Guereca,L., Bravo,A. (2001). Structural and functional studies of alpha-helix 5 region from Bacillus thuringiensis Cry1Ab delta-endotoxin.
Biochimica et Biophysica Acta (BBA) - Protein Structure And Molecular Enzymology,
1546 (1),
122-131.
Artículo
240 - Soberon,M., Perez,R.V., Nunez-Valdez,M.E., Lorence,A., Gomez,I., Sanchez,J., Bravo,A. (2000). Evidence for intermolecular interaction as a necessary step for pore-formation activity and toxicity of Bacillus thuringiensis Cry1Ab toxin.
Fems Microbiology Letters,
191 (2),
221-225.
Artículo
241 - Guereca,L., Bravo,A. (1999). The oligomeric state of Bacillus thuringiensis Cry toxins in solution.
Biochimica et Biophysica Acta (BBA) - Protein Structure And Molecular Enzymology,
1429 (2),
342-350.
Artículo
242 - Bravo,A., Sarabia,S., Lopez,L., Ontiveros,H., Abarca,C., Ortiz,A., Ortiz,M., Lina,L., Villalobos,F.J., Pena,G., Nunez-Valdez,M.E., Soberon,M., Quintero,R. (1998). Characterization of cry genes in a Mexican Bacillus thuringiensis strain collection.
Applied and Environmental Microbiology,
64 (12),
4965-4972.
Artículo
243 - Bohorova,N., Cabrera,M., Abarca,C., Quintero,R., Maciel,A.M., Brito,R.M., Hoisington,D., Bravo,A. (1997). Susceptibility of four tropical lepidopteran maize pests to Bacillus thuringiensis CryI-type insecticidal toxins.
Journal Of Economic Entomology,
90 (2),
412-415.
Revisión
244 - Bravo,A. (1997). Phylogenetic relationships of Bacillus thuringiensis delta-endotoxin family proteins and their functional domains.
Journal of Bacteriology,
179 (9),
2793-2801.
Artículo
245 - Flores,H., Soberon,X., Sanchez,J., Bravo,A. (1997). Isolated domain II and III from the Bacillus thuringiensis Cry1Ab delta-endotoxin binds to lepidopteran midgut membranes.
FEBS Letters,
414 (2),
313-318.
Artículo
246 - Lorence,A., Darszon,A., Bravo,A. (1997). Aminopeptidase dependent pore formation of Bacillus thuringiensis Cry1Ac toxin on Trichoplusia ni membranes.
FEBS Letters,
414 (2),
303-307.
Artículo
247 - Aranda,E., Sanchez,J., Peferoen,M., Guereca,L., Bravo,A. (1996). Interactions of Bacillus thuringiensis crystal proteins with the midgut epithelial cells of Spodoptera frugiperda (Lepidoptera: Noctuidae).
Journal of Invertebrate Pathology,
68 (3),
203-212.
Artículo
248 - Bravo,A., Agaisse,H., Salamitou,S., Lereclus,D. (1996). Analysis of cryIAa expression in sigE and sigK mutants of Bacillus thuringiensis.
Molecular and General Genetics,
250 (6),
734-741.
*
Artículo
249 - Meza,R., Nunez-Valdez,M.E., Sanchez,J., Bravo,A. (1996). Isolation of Cry1Ab protein mutants of Bacillus thuringiensis by a highly efficient PCR site-directed mutagenesis system.
Fems Microbiology Letters,
145 (3),
333-339.
Artículo
250 - Salamitou,S., Agaisse,H., Bravo,A., Lereclus,D. (1996). Genetic analysis of cryIIIA gene expression in Bacillus thuringiensis.
Microbiology,
142 (Pt 8),
2049-2055.
*
Artículo
251 - Ceron,J., Ortiz,A., Quintero,R., Guereca,L., Bravo,A. (1995). Specific PCR primers directed to identify cryI and cryIII genes within a Bacillus thuringiensis strain collection.
Applied and Environmental Microbiology,
61 (11),
3826-3831.
Artículo
252 - Lorence,A., Darszon,A., Diaz,C., Lievano,A., Quintero,R., Bravo,A. (1995). Delta-endotoxins induce cation channels in Spodoptera frugiperda brush border membranes in suspension and in planar lipid bilayers.
FEBS Letters,
360 (3),
217-222.
Note
253 - Ceron,J., Covarrubias,L., Quintero,R., Ortiz,A., Ortiz,M., Aranda,E., Lina,L., Bravo,A. (1994). PCR analysis of the cryI insecticidal crystal family genes from Bacillus thuringiensis.
Applied and Environmental Microbiology,
60 (1),
353-356.
Artículo
254 - Guereca,L., Bravo,A., Quintero,R. (1994). Design of an aqueous two-phase system for the purification of ICP from Bacillus thuringiensis.
Process Biochemistry,
29 (3),
181-185.
Artículo
255 - Bravo,A., Quintero,R., Diaz,C., Martinez,A., Soberon,M. (1993). Efficiency of insecticidal crystal protein production in a Bacillus thuringiensis mutant with derepressed expression of the terminal oxidase aa3 during sporulation.
Applied Microbiology and Biotechnology,
39 (4-5),
558-562.
Artículo
256 - Bravo,A., Hendrikx,K., Jansens,S., Peferoen,M. (1992). Immunocytochemical analysis of specific binding of Bacillus thuringiensis insecticidal crystal proteins to lepidopteran and coleopteran mudgut membranes.
Journal of Invertebrate Pathology,
60 (3),
247-253.
Artículo
257 - Bravo,A., Jansens,S., Peferoen,M. (1992). Immunocytochemical localization of Bacillus thuringiensis insecticidal crystal proteins in intoxicated insects.
Journal of Invertebrate Pathology,
60 (3),
237-246.
Artículo
258 - Pereyra-Alferez,B., Bravo,A., Quintero,R., Soberon,X. (1992). The delta-endotoxin protein family displays a hydrophobic motif that might be implicated in toxicity.
Molecular Microbiology,
6 (15),
2095-2098.
Artículo
259 - Folch,J.L., Antaramian,A., Rodriguez,L., Bravo,A., Brunner,A., Gonzalez,A. (1989). Isolation and characterization of a Saccharomyces cerevisiae mutant with impaired glutamate synthase activity.
Journal of Bacteriology,
171 (12),
6776-6781.
*
Artículo
260 - Bravo,A., Mora,J. (1988). Ammonium assimilation in Rhizobium phaseoli by the glutamine synthetase-glutamate synthase pathway.
Journal of Bacteriology,
170 (2),
980-984.
*
Note
261 - Bravo,A., Becerril,B., Mora,J. (1988). Introduction of the Escherichia coli gdhA gene into Rhizobium phaseoli: effect on nitrogen fixation.
Journal of Bacteriology,
170 (2),
985-988.
*
Internacional
262 - Bravo,A., Pacheco,S., Gomez,I., Soberon,M. (2023). Mode of action of Bacillus thuringiensis Cry pesticidal proteins. Insecticidal Proteins and RNAi in the Control of Insects.
Advances in Insect Physiology,
55-92,
65,
Cambridge, Mass.: Academic Press Inc..
Internacional
263 - Soberon,M., Bravo,A., Blanco,C.A. (2023). Strategies to Reduce Insecticide Use in Agricultural Production [Update]. Sustainable Food Science - A Comprehensive Approach: Volumes 1-4.
507-5014,
1-4,
Amsterdam: Elsevier.
Nacional
264 - Bravo de la Parra,M.,A., Soberon Chavez,M. (2019). Desarrollos biotecnológicos en algodonero. Algodón GM en Mexico: 20 años de siembra y experiencia.
43-52,
Cd Mexico: UNAM,
1a ed.
Internacional
265 - Bravo,A., Gill,S.S., Soberon,M. (2019). Bacillus thuringiensis: Mechanisms and use [This article is an update of A. Bravo, M. Soberón, S.S. Gill, 6.6 - Bacillus thuringiensis: Mechanisms and Use, Comprehensive Molecular Insect Science, edited by Lawrence I. Gilbert, Elsevier, 2005, pp. 175-205.]. Encyclopedia of Microbiology.
307-332,
4a.
Internacional
266 - Soberon, M., Monnerat, R., Bravo, A. (2018). Mode of Action of Cry Toxins from Bacillus thuringiensis and Resistance Mechanisms. Microbial Toxins.
Toxinology,
15-27,
Dordrecht: Springer.
Internacional
267 - Bravo, A., Pacheco, S., Gomez, I., Garcia-Gomez, B., Onofre, J., Soberon, M. (2017). Insecticidal Proteins from Bacillus thuringiensis and Their Mechanism of Action. Bacillus thuringiensis and Lysinibacillus sphaericus: Characterization and use in the field of biocontrol.
53-66,
Cham: Springer.
Internacional
268 - Soberon,M., Bravo,A., Blanco,C.A. (2016). Strategies to Reduce Insecticide Use in Agricultural Production. Reference Module in Food Science. .
Internacional
269 - Soberon,M., Monnerat,R., Bravo,A. (2016). Mode of Action of Cry Toxins from Bacillus thuringiensis and Resistance Mechanisms. Microbial Toxins.
1-13,
Dordrecht.
Internacional
270 - Bravo, A., Martinez-de-Castro, D. L., Sanchez-Quintana, J., Canton, P. E., Mendoza, G., Gomez, I., Pacheco, S., Garcia-Gomez, B. I., Onofre, J., Ocelotl, J., Soberon, M. (2015). Mechanism of action of Bacillus thuringiensis insecticidal toxins and their use in the control of insect pests. Comprehensive Sourcebook of Bacterial Protein Toxins.
858-873,
4a ed.
Internacional
271 - Bravo,A., Gomez,I., Mendoza,G., Gaytan,M., Soberon,M. (2015). Different models of the mode of action of Bt 3d-Cry toxins. Bt resistance - characterization and strategies for GM crops expressing Bacillus thuringiensis toxins.
56-68,
Oxford.
Editorial Material
272 - Bravo,A., Soberon,M., Gao,Y. (2015). Preface. Bt Resistance: Characterization and Strategies for GM Crops Producing Bacillus thuringiensis Toxins.
xi-xii,
Oxford.
Internacional
273 - Soberon,M., Garcia-Gomez,B.I., Pacheco,S., Sanchez-Quintana,J., Tabashnik,B.E., Bravo,A. (2015). Countering pest resistance with genetically modified Bt toxins. Bt resistance-characterization and strategies for GM crops expressing Bacillus thuringiensis.
CABI Biotechnology Series Volume: 4,
150-161,
Oxford.
Memoria in extenso
274 - Bravo,A., Martinez-de-Castro,D.L., Sanchez,J., Munoz-Garay,C., Matus,V., Canton,P.E., Lopez-Diaz,J., Portugal,L., Mendoza,G., Soberon,M. (2014). Mode of action of Bacillus thuringiensis toxins and their use in transgenic crops to control insect pests. Biotechnology: beyond borders.
Proceedings of the Indo-Mexico workshop on Biotechnology held at CSIR NCL, Pune, India from October 7-9, 2013.,
122-134.
Memoria in extenso
275 - Soberon,M., Gomez,I., Garcia-Gomez,B.I., Carmona,D., Ocelotl,J., Villanueva,F., Flores,B., Bravo,A. (2014). Mode of action of mosquitocidal toxins from Bacillus thuringiensis and their use in control of insect vectors of human diseases. Biotechnology: beyond borders.
Proceedings of the Indo-Mexico workshop on Biotechnology held at CSIR NCL, Pune, India from October 7-9, 2013.,
279-288.
Internacional
276 - Zuniga-Navarrete,F., Bravo,A., Soberon,M., Gomez,I. (2012). Role of GPI-anchored membrane receptors in the mode of action of Bacillus thuringiensis Cry toxins. Integrated Pest Management and Pest Control- Current and Future Tactics.
551-566.
Internacional
277 - Bravo,A., del Rincon-Castro,M.C., Ibarra,J.E., Soberon,M. (2011). Towards a healthy control of insect pest: Potential use of Microbial insecticides. Green trends in insect control.
266-299,
London.
Nacional
278 - Soberon,M., Bravo,A. (2011). Control de insectos con Bacillus thuringiensis, un método efectivo y compatible con el ambiente. V CICLO MUJER CIENCIA.
1-11,
Mexico,D.F:.
Internacional
279 - Bravo,A., Gill,S.S., Soberon,M. (2010). Bacillus thuringiensis Mechanisms and Use with addendum 2010. Insect Control Biological and Synthetic Agents.
Comprehensive Molecular Insect Science,
247-282.
Internacional
280 - Soberon,M., Pardo,L., Munoz-Garay,C., Sanchez,J., Gomez,I., Porta,H., Bravo,A. (2010). Pore Formation by Cry Toxins. Proteins: Membrane Binding and Pore Formation.
Advances in Experimental Medicine and Biology,
127-142,
Austin, TX: Landes Bioscience.
Nacional
281 - Bravo,A. (2008). Historia de cómo llegamos a proponer el modelo que describe cómo funcionan las toxinas Cry insecticidas producidas por la bacteria Bacillus thuringiensis. Aportaciones científicas y humanísticas mexicanas en el siglo XX.
92-103,
Mexico.
Nacional
282 - Soberon,M., Bravo,A. (2008). Las toxinas Cry de Bacillus thuringiensis: modo de acción y consecuencias de su aplicación. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 27.
303-314,
Mexico, D.F..
Memoria in extenso
283 - Gomez,I., Miranda-Rios,J., Arenas,I., Grande,R., Becerril,B., Bravo,A., Soberon,M. (2007). Identification of scFv Molecules that Recognize Loop 3 of Domain II and Domain III of Cry1Ab Toxin from Bacillus thuringiensis. 6th Pacific Rim Conference on the biotechnology of Bacillus thuringiensis and its Environmental Impact.
12-14,
Montreal.
Memoria in extenso
284 - Masson,L., Letowski,J., Bravo,A., Brousseau,R. (2007). Using DNA Microarrays for Assessing Crystal Protein Genes in Bacillus thuringiensis. Proceedings of the 6th Pacific Rim Conference on the Biotechnology of Bacillus thuringiensis and its Environmental Impact.
28-30.
Memoria in extenso
285 - Pardo,L., Gomez,I., Munoz-Garay,C., Jimenez-Juarez,N., Sanchez,J., Perez,C., Soberon,M., Bravo,A. (2007). Oligomer Formation of Different Cry Toxins Indicates that a Pre-Pore is an Essential Intermediate in the Mode of Action of the Three-Domain Cry Family. Proceedings of the 6th Pacific Rim Conference on the Biotechnology of Bacillus thuringiensis and its Environmental Impact.
7-8.
Memoria in extenso
286 - Perez,C., Fernandez,L.E., Sun,J.G., Folch,J.L., Gill,S.S., Soberon,M., Bravo,A. (2007). Cyt1Aa from Bacillus thuringiensis subsp. israelensis Synergizes Cry11Aa Toxin Activity by Functioning as a Membrane-Bound Receptor. Proceedings of the 6th Pacific Rim Conference on the Biotechnology of Bacillus thuringiensis and its Environmental Impact.
9-11.
Memoria in extenso
287 - Soberon,M., Gomez,I., Pardo,L., Munoz,C., Fernandez,L.E., Perez,C., Gill,S.S., Bravo,A. (2007). Important Interactions with membrane Receptors in the Mode of Action of Bacillus thuringiensis Cry toxins. 6th Pacific Rim Conference on the biotechnology of Bacillus thuringiensis and its Environmental Impact , cap 1.
1-6,
Montreal.
Nacional
288 - Munoz,R., Pardo,L., Sanchez-Quintana,J., Raussell.C., Soberon,M., Bravo,A. (2006). Mecanismos moleculares de insercion de la toxina Cry de Bacillus thuringiensis en membrana. La fisica biologica en Mexico.
1-27,
Mexico.
Internacional
289 - Bravo,A., Soberon,M., Gill,S.S. (2005). Bacillus thuringiensis, mechanism and use. Comprehensive molecular insect science.
175-205.
Internacional
290 - Soberon,M., Nuñez,M., Gomez I., Sanchez-Quintana,J., Bravo,A. (2004). Functional studies of helix a-5 region from Bacillus thuringiensis Cry1Ab d-endotoxin shows that conserved residues are important for pore formation and stability but not for oligomer formation. Pore-forming peptides and protein toxins.
Cellular and molecular mechanisms of toxin action ;v. 5,
90-101,
London ;New York.
Nacional
291 - Ibarra,A, Soberon,M., Bravo,A. (2003). La biotecnología y el control biológico de insectos. Fronteras de la Biología en los Inicios del Siglo XXI, Módulo III.
27-52,
Mexico,D.F..
Nacional
292 - Nunez-Valdez,M.E., Ramírez-Gama,R.M., Calderon,M.A., Hernandez,L., Romero.A., Rodríguez-Segura,Z., Aranda,E., Bravo,A., Villalobos-Hernandez,F.J. (2003). Bacterias entomopatógenas para el control de larvas de Phyllophaga spp. Estudios Sobre Coleópteros del Suelo en América.
347-359,
Puebla.
Internacional
293 - Bravo,A. (2001). Proteínas insecticidas de Bacillus thuringiensis. Bioinsecticidas: Fundamentos y aplicaciones de Bacillus thuringiensis en el control integrado de plagas.
73-88,
Navarra.
Nacional
294 - Soberon,M., Bravo,A. (2001). Bacillus thuringisensis y sus toxinas insecticidas. Microbios en linea.
221-235.
Internacional
295 - Monnerat,R., Bravo,A. (2000). Proteinas bioinsecticidas produzidas pela bacteria Bacillus thuringiensis. Contole biologico. .
Internacional
296 - Bravo,A. (1999). Comparative analysis of pore formation activity of cry toxins in membranes isolated from different insect orders. Biotechnology of Bacillus thuringiensis.
177-178,
Beijing, China..
Nacional
297 - Rocha Munive,M.G., Eguiarte Fruns,L.E., Soberon Chavez,M., Bravo de la Parra,M.A., Souza Saldivar,V. (2019). Algodón GM en Mexico: 20 años de siembra y experiencia.
136,
Cd Mexico: UNAM.
Internacional
298 - Soberon, M., Gao, Y. L., Bravo, A. (2015). Bt resistance- characterization and strategies for GM crops expressing Bacillus thuringiensis toxins.
CABI Biotechnology Series,
1-213,
Oxford: CABI.
Nacional
299 - Bravo,A., Arrieta,G, Benintende,G, Real,M.D., Espinoza,A.M., Ibarra.J., Monnerat,R., Orduz,S, Soberon,M. (2001). Metodologías utilizadas en investigación sobre bacterias entimopatógenas.
Mexico, D.F..
Editorial material
300 - Soberon,M., Bravo,A. (2025). The Future of Bt Proteins: From Pore Formation and Insect Resistance to the Next Generation of Pest Control.
Toxins,
17 (11),
522.
Editorial material
301 - Bravo,A., Soberon,M. (2023). Can microbial-based insecticides replace chemical pesticides in agricultural production?.
Microbial Biotechnology,
16 (11),
2011-2014.
Editorial Material
302 - Bravo,A., Soberon,M. (2022). Mining versus in vitro evolution for the selection of novel microbial insecticidal proteins.
Microbial Biotechnology,
15 (10),
2510-2520.
Nacional divulgación
303 - Lopez-Molina,S., Bravo,A. (2022). ¿Cómo eliminan los bioinsecticidas de las bacterias Bt a los mosquitos?.
Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM,
31 (Octubre-Diciembre).
divulgación
304 - Bravo,A., Soberon,M. (2021). Control biológico de plagas agrícolas de insectos.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
24,
25-27.
Preprint
305 - Wu,K.M., Xiao,Y.T., Xu,P.J., Wilson,K., Bravo,A., Soberon,M., Yang,X.M., Yuan,H., Jin,M.H., Zheng,W.G., Li,W.J. (2021). Rapid spread of a symbiotic virus in a major crop pest following wide-scale adoption of Bt-cotton in China.
bioRxiv,
Preprint posted February 10..
Nacional divulgación
306 - Sanchez-Flores,F.A. (2020). COVID-19: A seis meses del inicio de la pandemia (Segunda parte).
La Unión de Morelos,
22 de junio.
Preprint
307 - Velasquez,L.F., Canton,P.E., Sanchez-Flores,A., Bravo,A., Ceron,J. (2020). De novo transcriptome assembly of Premnotrypes vorax (Coleoptera: Curculionidae).
Research Square,
Preprint posted 17 Jan.
Nacional
308 - Samaniego-Gaxiola,J.A., Pedroza-Sandoval,A., Bravo,A., Sanchez,J.F., Pena-Chora,G., Mendoza-Flores,D., Chew-Madinaveitia,Y., Gaytan-Mascorro,A. (2019). Fumigación con ácido acético y antimicrobianos para disminuir mortandad de Chrysoperla carneapor infección indeterminada.
Revista Mexicana de Ciencias Agricolas,
10 (5),
973-986.
Preprint
309 - Wan,L., Lin,J., Du,H., Bravo,A., Soberon,M., Peng,D., Sun,M. (2018). Bacillus thuringiensis targets the host intestinal epithelial junctions for successful infection of Caenorhabditis elegans.
bioRxiv,
preprint posted June 4, 2018. Now published in Environmental Microbiology doi: 10.1111/1462-2920.14.
Divulgación
310 - Bravo-de-la-Parra,A. (2015). Viejas y nuevas tendencias en el uso de la fluorescencia para el analisis estructural de las proteínas y sus procesos.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
1,
26.
Nacional
311 - Ibarra,J.E., Castro,M.C., Galindo,E., Patino,M., Serrano,L., Garcia,R., Carrillo,J.A., Pereyra-Alferez,B., Alcazar-Pizana,A., Luna-Olvera,H., Galan-Wong,L., Pardo,L., Munoz-Garay,C., Gomez,I., Soberon,M., Bravo,A. (2006). [Microorganisms in the biological control of insects and phytopathogens].
Revista Latinoamericana de Microbiologia,
48 (2),
113-120.
Divulgación
312 - Aranda,E., Sanchez,J.F., Lina,L., Peferoen,M., Bravo,A. (1999). Analisis de la union in vitro e in vivo de las d-endotoxinas de Bacillus Thuringiensis al epitelio intestinal de Diatrea grandiosello.
BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria,
3,
95-105.
Divulgación
313 - Bravo,A., Lorence,A., Quintero,R. (1995). Biopesticidas compatibles con el medio ambiente: Bacillus thuringiensis, un modelo unico.
Biocontrol,
1 (1),
41-55.
314 - Bravo de la Parra, Ma Alejandra (2002). Estrategias moleculares que tiene Rhizobium phaseoli para manejar el nitrogeno en vida libre.
Licenciatura en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Mora, Jaime
315 - Bravo de la Parra, Ma Alejandra (1992). Relacion entre la asimilacion de amonio y la fijacion de nitrogeno en Rhizobium phaseoli.
CIFN,
Doctoradoen Investigacion Biomedica Basica,
UNAM.
*
Asesor: Mora, Jaime
Revisión
316 - Crickmore,N., Bravo,A., Heckel,D., Hernandez-Martinez,P., Nielsen-LeRoux,C., Soberon,M.. How Bacillus thuringiensis kills its insect host.
Journal of Invertebrate Pathology,
218 (September),
108643.
Artículo
317 - do Nascimento,N.A., Torres-Quintero,M.C., Garcia-Gomez,B.I., Gomez,I., Pacheco,S., Bravo,A., Soberon,M.. Engineering Bacillus thuringiensis Cyt1Aa to function as a surrogate receptor of Cry1A lepidopteran insecticidal proteins.
Pesticide Biochemistry And Physiology,
219 (April),
106970,
[Correction 107201 2026].
Artículo
318 - Gomez,I., Garcia-Gomez,B.I., do Nascimento,N.A., Infante,O., Canton,P.E., Pacheco,S., Pelaez-Aguilar,A.E., Sanchez,J., Soberon,M., Bravo,A.. Regulatory diversity in Bacillus thuringiensis cry genes reveals flexible evolutionary strategies for in vivo toxin expression.
PLoS Pathogens,
22 (3),
e1014017.
Artículo
319 - Kang,S., Bai,Y., Crickmore,N., Soberon,M., Zhou,X., Zhang,Y., Bravo,A., Guo,Z.. From gatekeeper to target: MAPK cascades as control circuits at the insect-microbe interface.
FEMS Microbiology Reviews,
50,
fuag027.
Artículo
320 - Quintana,A.J., Garcia-Suarez,R., Prieto,A., Sanchez,J., Gomez,I., Verduzco-Rosas,L.A., doNascimento,N., Lopez-Molina,S., Zhang,J., Soberon,M., Bravo,A., Pacheco,S.. Genome editing of ABCB6 Transporter Confers Resistance to Cypermethrin in the Major Pest of Corn, Spodoptera frugiperda.
Insect Biochemistry and Molecular Biology,
190 (May),
104537.
Revisión
321 - Sun,M., Shi,J., Bravo,A.. Caenorhabditis elegans: A Model System for Accelerating Studies on Bacillus thuringiensis Infection in Insects.
Annual Review of Entomology,
71 (1),
597-614.
Artículo
322 - Zhang,B., Liu,Z., Zhang,H., Bravo,A., Soberon,M., Zheng,J., Sun,M., Wang,K., Song,F., Peng,D.. Bacillus thuringiensis pathogenicity islands encode regulatory circuits controlling insecticidal Cry toxin expression during vegetative growth.
PLoS Pathogens,
22 (7),
e1014476.
Artículo
323 - Zhou,H., Li,Lixu, Gong,Y., Liu,H., Wu,H., Bravo,A., Soberon,M., Zheng,J., Peng,D., Sun,Bo, Sun,M.. Geographic and Seasonal Variation of Culturable Bacteria Associated with the Diseased Silkworm (Bombyx mori).
Current Research in Microbial Sciences,
10,
100529.
Artículo
324 - Huang,G., Wang,K., Li,F., Gao,S., Liu,H., Chen,F., Liu,Z., Chen,Y., Wang,C., Xu,M., Hu,B., Xie,C., Ma,Y., Dai,D., Li,Y., Li,X., Bo,D., Chen,L., Bravo,A., Soberon,M., Zheng,J., Peng,D., Sun,M.. Large-scale protein interactome reveals lineage-specific genes driving plant-parasitic nematode adaptive innovations.
Science Advances,
11 (33),
eadt5107.
Artículo
325 - Li,S., Wang,Z., Yang,Y., Niu,X., Fang,Y., Soberon,M., Bravo,A., Wu,G.X., Zhang,J.. Sequestosome 1 in Autophagy Regulates a Defense Response of the Striped Stem Borer to the Cry9Aa Protein.
Journal of Agricultural and Food Chemistry,
73 (18),
11030-11040.
Artículo
326 - Lopez-Molina,S., Guerrero,A., Pacheco,S., Wang,Z., Zhang,J., Sanchez,J., Zavala,G., Soberon,M., Bravo,A.. Cry11Aa toxin of Bacillus thuringiensis interactions with intracellular organelles in insect gut implicating actin depolymerization, massive endocytosis, and vesicle secretion.
International Journal of Biological Macromolecules,
314,
144350.
Artículo
327 - Pacheco,S., Chinas,M., Gomez,J.U., Pelaez-Aguilar,A.E., do Nascimento,N.A., Canton,P.E., Sanchez,J., Lopez-Molina,S., Gomez,I., Soberon,M., Bravo,A.. ABC transporters knockout in Aedes aegypti induces upregulation of paralogous genes, avoiding resistance development to Bacillus thuringiensis Cry toxins.
PLoS ONE,
20 (7),
e0327221.
Artículo
328 - Sun,D., Xu,Q.C., Guo,L., Bai,Y., Shentu,X., Yu,X., Crickmore,N., Zou,X.G., Bravo,A., Soberon,M., Zhang,Y.J., Guo,Z.J.. The role of GPI-anchored membrane-bound alkaline phosphatase in the mode of action of Bt Cry1A toxins in the diamondback moth.
Fundamental Research,
5 (2),
674-682.
Artículo
329 - Tan,S., Shang,Z., Jia,H., Huang,J., Geng,L., Shu,C., Soberon,M., Bravo,A., Shi,W., Zhang,J., Wei,H.. Enhancing Bacillus thuringiensis Cry8Ea1 toxicity: Insights into protease sensitivity for the evolutionary adaptation of Cry toxins to insect hosts.
International Journal of Biological Macromolecules,
308 (1),
142246.
Artículo
330 - Wang,K., Xu,J., Lu,X., Yin,P., Chen,L., Zhao,Z., Bravo,A., Soberon,M., Zheng,J., Sun,M., Peng,D.. Two novel trimethoprim resistance genes, dfra50 and dfra51, identified in phage-plasmids.
Antimicrobial Agents and Chemotherapy,
69 (7),
e0169524.
Artículo
331 - Wang,K., Xu,J., Li,X., Zhu,P., Suo,R., Lu,X., Luo,H., Chen,L., Wen,R., Zheng,C., Bravo,A., Soberon,M., Zheng,J., Sun,M., Peng,D.. Evolutionary selection of trimethoprim-resistant dfrA genes in lytic phages affects phage and host fitness during infection.
Science Advances,
11 (39),
eadt4817.
Editorial material
332 - Soberon,M., Bravo,A.. The Future of Bt Proteins: From Pore Formation and Insect Resistance to the Next Generation of Pest Control.
Toxins,
17 (11),
522.
Artículo
333 - de Oliveira,J.L., Gomez,I., Sanchez,J., Soberon,M., Polanczyk,R.A., Bravo,A.. Performance insights into spray-dryer microencapsulated Bacillus thuringiensis cry pesticidal proteins with gum arabic and maltodextrin for effective pest control.
Applied Microbiology and Biotechnology,
108 (1),
181.
Artículo
334 - He,X., Yang,Y., Soberon,M., Bravo,A., Zhang,L., Zhang,J., Wang,Z.. Bacillus thuringiensis Cry9Aa Insecticidal Protein Domain I Helices In3 and In4 Are Two Core Regions Involved in Oligomerization and Toxicity.
Journal of Agricultural and Food Chemistry,
72 (2),
1321-1329.
Artículo
335 - Huang,G., Cong,Z., Liu,Z., Chen,F., Bravo,A., Soberon,M., Zheng,J., Peng,D., Sun,M.. Silencing Ditylenchus destructor cathepsin L-like cysteine protease has negative pleiotropic effect on nematode ontogenesis.
Scientific Reports,
14 (1),
10030.
Artículo
336 - Infante,O., Gomez,I., Pelaez-Aguilar,A.E., Verduzco-Rosas,L.A., Garcia-Suarez,R., Garcia-Gomez,B.I., Wang,Z., Zhang,J., Guerrero,A., Bravo,A., Soberon,M.. Insights into the structural changes that trigger receptor binding upon proteolytic activation of Bacillus thuringiensis Vip3Aa insecticidal protein.
PLoS Pathogens,
20 (12),
e1012765,
[Correction e1014366, 2026].
Artículo
337 - Pacheco,S., Gallegos,A.S., Pelaez-Aguilar,A.E., Sanchez,J., Gomez,I., Soberon,M., Bravo,A.. CRISPR-Cas9 knockout of membrane-bound alkaline phosphatase or cadherin does not confer resistance to Cry toxins in Aedes aegypti.
PLoS Neglected Tropical Diseases,
18 (6),
e0012256.
Artículo
338 - Wang,H.X., Li,A.J., Bian,H.R., Jin,L., Ma,S.L., Wang,H.Y., Yang,Y.B., Bravo,A., Soberon,M., Liu,K.Y.. Transcriptional regulation of Cry2Ab toxin receptor ABCA2 gene in insects involves GATAe and splicing of ant 5' UTR iron.
Pesticide Biochemistry And Physiology,
206,
106211.
Artículo
339 - Wang,Z., Yang,Y., Li,S., Ma,W., Wang,K., Soberon,M., Yan,Sh., Shen,J., Francis,F., Bravo,A., Zhang,J.. JAK/STAT signaling regulated intestinal regeneration defends insect pests against pore-forming toxins produced by Bacillus thuringiensis.
PLoS Pathogens,
24 (20),
e1011823.
Artículo
340 - Chen,F., Pang,C., Zheng,Z., Zhou,W., Guo,Z., Xiao,D., Du,H., Bravo,A., Soberon,M., Sun,M., Peng,D.. Aminopeptidase MNP-1 triggers intestine protease production by activating daf-16 nuclear location to degrade pore-forming toxins in Caenorhabditis elegans.
PLoS Pathogens,
19 (7),
e1011507.
Artículo
341 - Garcia-Gomez,B.I., Sanchez,T.A., Cano,S.N., do Nascimento,N.A., Bravo,A., Soberon,M.. Insect chaperones Hsp70 and Hsp90 cooperatively enhance toxicity of Bacillus thuringiensis Cry1A toxins and counteract insect resistance.
Frontiers in Immunology,
14,
1151943.
Artículo
342 - Pacheco,S., Gomez,I., Soberon,M., Bravo,A.. A major conformational change of N-terminal helices of Bacillus thuringiensis Cry1Ab insecticidal protein is necessary for membrane insertion and toxicity.
Febs Journal,
290 (10),
2692-2705.
Revisión
343 - Pacheco,S., Gomez,I., Pelaez-Aguilar,A.E., Verduzco-Rosas,L.A., Garcia-Suarez,R., do Nascimento,N.A., Rivera-Najera,L.Y., Canton,P.E., Soberon,M., Bravo,A.. Structural changes upon membrane insertion of the insecticidal pore-forming toxins produced by Bacillus thuringiensis.
Frontiers in Insect Science,
3,
1188891.
Artículo
344 - Velasquez C,L.F., Canton,P.E., Sanchez-Flores,A., Soberon,M., Bravo,A., Ceron S,J.A.. Identification of Cry toxin receptor genes homologs in a de novo transcriptome of Premnotrypes vorax (Coleoptera: Curculionidae).
PLoS ONE,
18 (9),
e0291546.
Artículo
345 - Wang,K., Shu,C., Bravo,A., Soberon,M., Zhang,H., Crickmore,N., Zhang,J.. Development of an Online Genome Sequence Comparison Resource for Bacillus cereus sensu lato Strains Using the Efficient Composition Vector Method.
Toxins (Basel),
15 (6),
393.
Artículo
346 - Wei,W., Wang,L., Pan,S., Wang,H., Xia,Z., Liu,L., Xiao,Y., Bravo,A., Soberon,M., Yang,Y., Liu,K.. Helicoverpa armigera GATAe transcriptional factor regulates the expression of Bacillus thuringiensis Cry1Ac receptor gene ABCC2 by its interplay with additional transcription factors.
Pesticide Biochemistry And Physiology,
194,
105516.
Internacional
347 - Bravo,A., Pacheco,S., Gomez,I., Soberon,M.. Mode of action of Bacillus thuringiensis Cry pesticidal proteins. Insecticidal Proteins and RNAi in the Control of Insects.
Advances in Insect Physiology,
55-92,
65,
Cambridge, Mass.: Academic Press Inc..
Internacional
348 - Soberon,M., Bravo,A., Blanco,C.A.. Strategies to Reduce Insecticide Use in Agricultural Production [Update]. Sustainable Food Science - A Comprehensive Approach: Volumes 1-4.
507-5014,
1-4,
Amsterdam: Elsevier.
Editorial material
349 - Bravo,A., Soberon,M.. Can microbial-based insecticides replace chemical pesticides in agricultural production?.
Microbial Biotechnology,
16 (11),
2011-2014.
Revisión
350 - do Nascimento,J., Goncalves,K.C., Dias,N.P., de Oliveira,J.L., Bravo,A., Polanczyk,R.A.. Adoption of Bacillus thuringiensis-based biopesticides in agricultural systems and new approaches to improve their use in Brazil.
Biological Control,
165,
104792.
Artículo
351 - Guo,L., Cheng,Z., Qin,J., Sun,D., Wang,S., Wu,Q., Crickmore,N., Zhou,X., Bravo,A., Soberon,M., Guo,Z., Zhang,Y.. MAPK-mediated transcription factor GATAd contributes to Cry1Ac resistance in diamondback moth by reducing PxmALP expression.
PLoS Genetics,
18 (2),
e1010037.
Artículo
352 - Guo,Z., Guo,L., Qin,J., Ye,F., Sun,D., Wu,Q., Wang,S., Crickmore,N., Zhou,X., Bravo,A., Soberon,M., Zhang,Y.. A single transcription factor facilitates an insect host combating Bacillus thuringiensis infection while maintaining fitness.
Nature Communications,
13 (1),
6024.
Artículo
353 - Liao,C., Jin,M., Cheng,Y., Yang,Y., Soberon,M., Bravo,A., Liu,K., Xiao,Y.. Bacillus thuringiensis Cry1Ac Protoxin and Activated Toxin Exert Differential Toxicity Due to a Synergistic Interplay of Cadherin with ABCC Transporters in the Cotton Bollworm.
Applied and Environmental Microbiology,
88 (7),
e0250521.
Artículo
354 - Sun,D., Zhu,L., Guo,L., Wang,S., Wu,Q., Crickmore,N., Zhou,X., Bravo,A., Soberon,M., Guo,Z., Zhang,Y.. A versatile contribution of both aminopeptidases N and ABC transporters to Bt Cry1Ac toxicity in the diamondback moth.
BMC Biology,
20 (1),
33.
Editorial Material
355 - Bravo,A., Soberon,M.. Mining versus in vitro evolution for the selection of novel microbial insecticidal proteins.
Microbial Biotechnology,
15 (10),
2510-2520.
Nacional divulgación
356 - Lopez-Molina,S., Bravo,A.. ¿Cómo eliminan los bioinsecticidas de las bacterias Bt a los mosquitos?.
Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM,
31 (Octubre-Diciembre).
Revisión
357 - de Oliveira,J.L., Fraceto,L.F., Bravo,A., Polanczyk,R.A.. Encapsulation Strategies for Bacillus thuringiensis: From Now to the Future.
Journal of Agricultural and Food Chemistry,
69 (16),
4564-4577.
Artículo
358 - Guo,Z., Kang,S., Wu,Q., Wang,S., Crickmore,N., Zhou,X., Bravo,A., Soberon,M., Zhang,Y.. The regulation landscape of MAPK signaling cascade for thwarting Bacillus thuringiensis infection in an insect host.
PLoS Pathogens,
17 (9),
e1009917.
Artículo
359 - Jin,M., Yang,Y., Shan,Y., Chakrabarty,S., Cheng,Y., Soberon,M., Bravo,A., Liu,K., Wu,K., Xiao,Y.. Two ABC transporters are differentially involved in the toxicity of two Bacillus thuringiensis Cry1 toxins to the invasive crop-pest Spodoptera frugiperda (J. E. Smith).
Pest Management Science,
77 (3),
1492-1501.
Artículo
360 - Liu,Y., Jin,M., Wang,L., Wang,H., Xia,Z., Yang,Y., Bravo,A., Soberon,M., Xiao,Y., Liu,K.. SfABCC2 transporter extracellular loops 2 and 4 are responsible for the Cry1Fa insecticidal specificity against Spodoptera frugiperda.
Insect Biochemistry and Molecular Biology,
135,
103608.
Artículo
361 - Lopez-Molina,S., do Nascimento,N.A., Silva-Filha,M.H.N.L., Guerrero,A., Sanchez,J., Pacheco,S., Gill,S.S., Soberon,M., Bravo,A.. In vivo nanoscale analysis of the dynamic synergistic interaction of Bacillus thuringiensis Cry11Aa and Cyt1Aa toxins in Aedes aegypti.
PLoS Pathogens,
17 (1),
e1009199.
Artículo
362 - Pacheco,S., Gomez,I., Chinas,M., Sanchez,J., Soberon,M., Bravo,A.. Whole Genome Sequencing Analysis of Bacillus thuringiensis GR007 Reveals Multiple Pesticidal Protein Genes.
Frontiers in Microbiology,
12,
3268.
Artículo
363 - Sena da Silva,I.H., Gomez,I., Pacheco,S., Sanchez,J., Zhang,J., Luque Castellane,T.C., Aparecida Desiderio J., Soberon,M., Bravo,A., Polanczyk,R.A.. Bacillus thuringiensis Cry1Ab domain III -16 is involved in binding to prohibitin which correlates with toxicity against Helicoverpa armigera (Lepidoptera: Noctuidae).
Applied and Environmental Microbiology,
87 (2),
e01930-20.
Artículo
364 - Shi,J., Zhang,F., Chen,L., Bravo,A., Soberon,M., Sun,M.. Systemic mitochondrial disruption is a key event in the toxicity of bacterial pore-forming toxins to Caenorhabditis elegans.
Environmental Microbiology,
23 (9),
4896-4907.
Revisión
365 - Silva-Filha,M.H.N.L., Romao,T.P., Rezende,T.M.T., Carvalho,K.D.S., de Menezes,H.S.G., do Nascimento,N.A., Soberon,M., Bravo,A.. Bacterial toxins active against mosquitoes: Mode of action and resistance.
Toxins,
13 (8),
523.
Artículo
366 - Wang,Z., Gan,C., Wang,J., Bravo,A., Soberon,M., Yang,Q., Zhang,J.. Nutrient conditions determine the localization of Bacillus thuringiensis Vip3Aa protein in the mother cell compartment.
Microbial Biotechnology,
14 (1),
551-560.
Artículo
367 - Xiao,Y., Li,W., Yang,X., Xu,P., Jin,M., Yuan,H., Zheng,W., Soberon,M., Bravo,A., Wilson,K., Wu,K.. Rapid spread of a densovirus in a major crop pest following wide-scale adoption of Bt-cotton in China.
Elife,
10,
e66913.
Artículo
368 - Yang,Y., Huang,X., Yuan,W., Xiang,Y., Guo,X., Wei,W., Soberon,M., Bravo,A., Liu,K.. Bacillus thuringiensis cry toxin triggers autophagy activity that may enhance cell death.
Pesticide Biochemistry And Physiology,
171,
104728.
Artículo
369 - Zhang,D., Jin,M., Yang,Y., Zhang,J., Yang,Y., Liu,K., Soberon,M., Bravo,A., Xiao,Y., Wu,K.. Synergistic resistance of Helicoverpa armigera to Bt toxins linked to cadherin and ABC transporters mutations.
Insect Biochemistry and Molecular Biology,
137,
103635.
divulgación
370 - Bravo,A., Soberon,M.. Control biológico de plagas agrícolas de insectos.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
24,
25-27.
Preprint
371 - Wu,K.M., Xiao,Y.T., Xu,P.J., Wilson,K., Bravo,A., Soberon,M., Yang,X.M., Yuan,H., Jin,M.H., Zheng,W.G., Li,W.J.. Rapid spread of a symbiotic virus in a major crop pest following wide-scale adoption of Bt-cotton in China.
bioRxiv,
Preprint posted February 10..
Artículo
372 - Anaya,P., Onofre,J., Torres-Quintero,M.C., Sanchez,J., Gill,S.S., Bravo,A., Soberon,M.. Oligomerization is a key step for Bacillus thuringiensis Cyt1Aa insecticidal activity but not for toxicity against red blood cells.
Insect Biochemistry and Molecular Biology,
119,
103317.
Artículo
373 - do Nascimento,N.A., Torres-Quintero,M.C., Lopez-Molina,S., Pacheco,S., Romao,T.P., Pereira-Neves,A., Soberon,M., Bravo,A., Silva-Filha,M.H.N.L.. Functional Bacillus thuringiensis Cyt1Aa is necessary to synergize Lysinibacillus sphaericus Binary toxin against Bin-resistant and refractory mosquito species.
Applied and Environmental Microbiology,
86 (7),
02770-19.
Artículo
374 - Gomez,I., Ocelotl,J., Sanchez,J., Aguilar-Medel,S., Pena-Chora,G., Lina-Garcia,L., Bravo,A., Soberon,M.. Bacillus thuringiensis Cry1Ab domain III beta-22 mutants with enhanced toxicity to Spodoptera frugiperda (J. E. Smith).
Applied and Environmental Microbiology,
86 (22),
e01580-20.
Artículo
375 - Gong,L., Kang,S., Zhou,J., Sun,D., Guo,L., Qin,J., Zhu,L., Bai,Y., Ye,F., Akami,M., Wu,Q., Wang,S., Xu,B., Yang,Z., Bravo,A., Soberon,M., Guo,Z., Wen,L., Zhang,Y.. Reduced Expression of a Novel Midgut Trypsin Gene Involved in Protoxin Activation Correlates with Cry1Ac Resistance in a Laboratory-Selected Strain of Plutella xylostella (L.).
Toxins (Basel),
12 (2).
Artículo
376 - Guo,Z., Gong,L., Kang,S., Zhou,J., Sun,D., Qin,J., Guo,L., Zhu,L., Bai,Y., Bravo,A., Soberon,M., Zhang,Y.. Comprehensive analysis of Cry1Ac protoxin activation mediated by midgut proteases in susceptible and resistant Plutella xylostella (L.).
Pesticide Biochemistry And Physiology,
163,
23-30.
Artículo
377 - Onofre,J., Pacheco,S., Torres-Quintero,M.C., Gill,S.S., Soberon,M., Bravo,A.. The Cyt1Aa toxin from Bacillus thuringiensis inserts into target membranes via different mechanisms in insects, red blood cells, and lipid liposomes.
Journal of Biological Chemistry,
295 (28),
9606-9617.
Artículo
378 - Pacheco,S., Quiliche,J.P.J., Gomez,I., Sanchez,J., Soberon,M., Bravo,A.. Rearrangement of N-Terminal alpha-Helices of Bacillus thuringiensis Cry1Ab Toxin Essential for Oligomer Assembly and Toxicity.
Toxins (Basel),
12 (10),
E647.
Artículo
379 - Shabbir,M.Z., Zhang,T., Prabu,S., Wang,Y.Q., Wang,Z.Y., Bravo,A., Soberon,M., He,K.. Identification of Cry1Ah-binding proteins through pull down and gene expression analysis in Cry1Ah-resistant and susceptible strains of Ostrinia furnacalis.
Pesticide Biochemistry And Physiology,
163,
200-208.
Artículo
380 - Shu,C., Yan,G., Huang,S., Geng,Y., Soberon,M., Bravo,A., Geng,L., Zhang,J.. Characterization of Two Novel Bacillus thuringiensis Cry8 Toxins Reveal Differential Specificity of Protoxins or Activated Toxins against Chrysomeloidea Coleopteran Superfamily.
Toxins (Basel),
12 (10).
Artículo
381 - Wang,Z., Wang,K., Bravo,A., Soberon,M., Cai,J., Shu,C., Zhang,J.. Coexistence of cry9 with the vip3A Gene in an Identical Plasmid of Bacillus thuringiensis Indicates Their Synergistic Insecticidal Toxicity.
Journal of Agricultural and Food Chemistry,
68 (47),
14081-14090.
Artículo
382 - Wei,W., Pan,S., Ma,Y., Xiao,Y., Yang,Y., He,S., Bravo,A., Soberon,M., Liu,K.. GATAe transcription factor is involved in Bacillus thuringiensis Cry1Ac toxin receptor gene expression inducing toxin susceptibility.
Insect Biochemistry and Molecular Biology,
118,
103306.
Artículo
383 - Zhang,J., Jin,M., Yang,Y., Liu,L., Yang,Y., Gomez,I., Bravo,A., Soberon,M., Xiao,Y., Liu,K.. The Cadherin Protein Is Not Involved in Susceptibility to Bacillus thuringiensis Cry1Ab or Cry1Fa Toxins in Spodoptera frugiperda.
Toxins (Basel),
12 (6),
375.
Artículo
384 - Zheng,Z., Zhang,Y., Liu,Z., Dong,Z., Xie,C., Bravo,A., Soberon,M., Mahillon,J., Sun,M., Peng,D.. The CRISPR-Cas systems were selectively inactivated during evolution of Bacillus cereus group for adaptation to diverse environments.
ISME Journal,
14 (6),
1479-1493.
Nacional divulgación
385 - Sanchez-Flores,F.A.. COVID-19: A seis meses del inicio de la pandemia (Segunda parte).
La Unión de Morelos,
22 de junio.
Preprint
386 - Velasquez,L.F., Canton,P.E., Sanchez-Flores,A., Bravo,A., Ceron,J.. De novo transcriptome assembly of Premnotrypes vorax (Coleoptera: Curculionidae).
Research Square,
Preprint posted 17 Jan.
Artículo
387 - Garcia-Gomez,B.I., Cano,S.N., Zagal,E.E., Dantan-Gonzalez,E., Bravo,A, Soberon,M. Insect Hsp90 Chaperone Assists Bacillus thuringiensis Cry Toxicity by Enhancing Protoxin Binding to the Receptor and by Protecting Protoxin from Gut Protease Degradation.
MBio,
10 (6),
e02775-19.
Artículo
388 - Ma,Y., Zhang,J., Xiao,Y., Yang,Y., Liu,C., Peng,R., Yang,Y., Bravo,A., Soberon,M., Liu,K.. The Cadherin Cry1Ac Binding-Region is Necessary for the Cooperative Effect with ABCC2 Transporter Enhancing Insecticidal Activity of Bacillus thuringiensis Cry1Ac Toxin.
Toxins (Basel),
11 (9),
538.
Artículo
389 - Wan,L., Lin,J., Du,H., Bravo,A., Soberon,M., Sun,M.. Bacillus thuringiensis targets the host intestinal epithelial junctions for successful infection of Caenorhabditis elegans.
Environmental Microbiology,
21 (3),
1086-1098.
Nacional
390 - Bravo de la Parra,M.,A., Soberon Chavez,M.. Desarrollos biotecnológicos en algodonero. Algodón GM en Mexico: 20 años de siembra y experiencia.
43-52,
Cd Mexico: UNAM,
1a ed.
Internacional
391 - Bravo,A., Gill,S.S., Soberon,M.. Bacillus thuringiensis: Mechanisms and use [This article is an update of A. Bravo, M. Soberón, S.S. Gill, 6.6 - Bacillus thuringiensis: Mechanisms and Use, Comprehensive Molecular Insect Science, edited by Lawrence I. Gilbert, Elsevier, 2005, pp. 175-205.]. Encyclopedia of Microbiology.
307-332,
4a.
Nacional
392 - Rocha Munive,M.G., Eguiarte Fruns,L.E., Soberon Chavez,M., Bravo de la Parra,M.A., Souza Saldivar,V.. Algodón GM en Mexico: 20 años de siembra y experiencia.
136,
Cd Mexico: UNAM.
Nacional
393 - Samaniego-Gaxiola,J.A., Pedroza-Sandoval,A., Bravo,A., Sanchez,J.F., Pena-Chora,G., Mendoza-Flores,D., Chew-Madinaveitia,Y., Gaytan-Mascorro,A.. Fumigación con ácido acético y antimicrobianos para disminuir mortandad de Chrysoperla carneapor infección indeterminada.
Revista Mexicana de Ciencias Agricolas,
10 (5),
973-986.
Artículo
394 - Bravo,A., Lopez-Diaz,J.A., Yamamoto,T., Harding,K., Zhao,J.J., Mendoza,G., Onofre,J., Torres,M.C., Nelson,M.E., Wu,G., Sethi,A., Soberon,M.. Susceptible and mCry3A resistant corn rootworm larvae killed by a non-hemolytic Bacillus thuringiensis Cyt1Aa mutant.
Scientific Reports,
8 (1),
17805.
Artículo
395 - Gomez, I., Rodriguez-Chamorro, D.E., Flores-Ramirez, G., Grande, R., Zuniga, F., Portugal, F.J., Sanchez, J., Pacheco, S., Bravo, A., Soberon, M.. Spodoptera frugiperda (J. E. Smith) aminopeptidase N1 is functional receptor of Bacillus thuringiensis Cry1Ca toxin.
Applied and Environmental Microbiology,
84 (17),
UNSP e01089-18.
Artículo
396 - Gomez, I., Ocelotl, J., Sanchez, J., Lima, C., Martins, E., Rosales-Juarez, A., Aguilar-Medel, S., Abad, A., Dong, H., Monnerat, R., Pena, G., Zhang, J., Nelson, M., Wu, G., Bravo, A., Soberon, M.. Enhancement of Bacillus thuringiensis Cry1Ab and Cry1Fa toxicity to Spodoptera frugiperda by domain III mutations indicates two limiting steps in toxicity as defined by receptor binding and protein stability.
Applied and Environmental Microbiology,
84 (20),
e01393-18.
Artículo
397 - Liu, L., Chen, Z., Yang, Y., Xiao, Y., Liu, C., Ma, Y., Soberon, M., Bravo, A., Yang, Y., Liu, K.. A single amino acid polymorphism in ABCC2 loop 1 is responsible of differential toxicity of Bacillus thuringiensis Cry1Ac toxin in different Spodoptera (Noctuidae) species.
Insect Biochemistry and Molecular Biology,
100,
59-65.
Artículo
398 - Liu, Y., Wang, Y., Shu, C., Lin, K., Song, F., Bravo, A., Soberon, M., Zhang, J.. Cry64Ba and Cry64Ca, two ETX/MTX2 Bacillus thuringiensis insecticidal proteins against hemipteran pests.
Applied and Environmental Microbiology,
84 (3),
e01996-17.
Artículo
399 - Pacheco, S., Gomez, I., Sanchez, J., Garcia-Gomez, B.I., Czajkowsky, D.M., Zhang, J., Soberon, M., Bravo, A.. Helix alpha-3 inter-molecular salt bridges and conformational changes are essential for toxicity of Bacillus thuringiensis 3D-Cry toxin family.
Scientific Reports,
8 (1),
10331.
Artículo
400 - Pena-Cardena,A., Grande,R., Sanchez,J., Tabashnik,B.E., Bravo,A., Soberon,M., Gomez,I.. The C-terminal protoxin domain of Bacillus thuringiensis Cry1Ab toxin has a functional role in binding to GPI-anchored receptors in the insect midgut.
Journal of Biological Chemistry,
293 (52),
20263-20272.
Artículo
401 - Rocha-Munive, M.G., Soberon, M., Castaneda, S., Niaves, E., Scheinvar, E., Eguiarte, L.E., Mota-Sanchez, D., Rosales-Robles, E., Nava-Camberos, U., Martinez-Carrillo, J.L., Blanco, C.A., Bravo, A., Souza, V.. Evaluation of the Impact of Genetically Modified Cotton After 20 Years of Cultivation in Mexico.
Frontiers in Bioengineering and Biotechnology,
6,
82.
Artículo
402 - Sena de Silva,I., Gomez,I., Sanchez,J., Martinez de Castro,D.L., Valicente,F.H., Soberon,M., Polanczyk,R.A., Bravo,A.. Identification of midgut membrane proteins from different instars of Helicoverpa armigera (Lepidoptera: Noctuidae) that bind to Cry1Ac toxin.
PLoS ONE,
13 (12),
e0207789.
Artículo
403 - Shabbir, M.Z., Quan, Y., Wang, Z., Bravo, A., Soberon, M., He, K.. Characterization of the Cry1Ah resistance in Asian corn Borer and its cross-resistance to other Bacillus thuringiensis toxins.
Scientific Reports,
8 (1),
234.
Revisión
404 - Soberon, M., Portugal, L., Garcia-Gomez, B.I., Sanchez, J., Onofre, J., Gomez, I., Pacheco, S., Bravo, A.. Cell lines as models for the study of Cry toxins from Bacillus thuringiensis.
Insect Biochemistry and Molecular Biology,
93,
66-78.
Artículo
405 - Torres-Quintero, M.C., Gomez, I., Pacheco, S., Sanchez, J., Flores, H., Osuna, J., Mendoza, G., Soberon, M., Bravo, A.. Engineering Bacillus thuringiensis Cyt1Aa toxin specificity from dipteran to lepidopteran toxicity.
Scientific Reports,
8 (1),
4989.
Artículo
406 - Wang, K., Shu, C., Soberon, M., Bravo, A., Zhang, J.. Systematic characterization of Bacillus Genetic Stock Center Bacillus thuringiensis strains using Multi-Locus Sequence Typing.
Journal of Invertebrate Pathology,
155,
5-13.
Artículo
407 - Wang, Z., Fang, L., Zhou, Z., Pacheco, S., Gomez, I., Song, F., Soberon, M., Zhang, J., Bravo, A.. Specific binding between Bacillus thuringiensis Cry9Aa and Vip3Aa toxins synergizes their toxicity against Asiatic rice borer (Chilo suppressalis).
Journal of Biological Chemistry,
293 (29),
11447-11458.
Internacional
408 - Soberon, M., Monnerat, R., Bravo, A.. Mode of Action of Cry Toxins from Bacillus thuringiensis and Resistance Mechanisms. Microbial Toxins.
Toxinology,
15-27,
Dordrecht: Springer.
Preprint
409 - Wan,L., Lin,J., Du,H., Bravo,A., Soberon,M., Peng,D., Sun,M.. Bacillus thuringiensis targets the host intestinal epithelial junctions for successful infection of Caenorhabditis elegans.
bioRxiv,
preprint posted June 4, 2018. Now published in Environmental Microbiology doi: 10.1111/1462-2920.14.
Artículo
410 - Chen, W.B., Lu, G.Q., Cheng, H.M., Liu, C.X., Xiao, Y.T., Xu, C., Shen, Z.C., Soberon, M., Bravo, A., Wu, K.M.. Transgenic cotton co-expressing chimeric Vip3AcAa and Cry1Ac confers effective protection against Cry1Ac-resistant cotton bollworm.
Transgenic Research,
26 (6),
763-774.
Artículo
411 - Jiang, J., Huang, Y., Shu, C., Soberon, M., Bravo, A., Liu, C., Song, F., Lai, J., Zhang, J.. Holotrichia oblita Midgut Proteins That Bind to Bacillus thuringiensis Cry8-Like Toxin and Assembly of the H. oblita Midgut Tissue Transcriptome.
Applied and Environmental Microbiology,
83 (12),
e00541-17.
Artículo
412 - Li, J., Ma, Y., Yuan, W., Xiao, Y., Liu, C., Wang, J., Peng, J., Peng, R., Soberon, M., Bravo, A., Yang, Y., Liu, K.. FOXA transcriptional factor modulates insect susceptibility to Bacillus thuringiensis Cry1Ac toxin by regulating the expression of toxin-receptor ABCC2 and ABCC3 genes.
Insect Biochemistry and Molecular Biology,
88,
1-11.
Artículo
413 - Martinez de Castro, D.L, Garcia-Gomez, B.I., Gomez, I., Bravo, A., Soberon, M.. Identification of Bacillus thuringiensis Cry1AbMod binding-proteins from Spodoptera frugiperda.
Peptides,
98,
99-105.
Artículo
414 - Ocelotl, J., Sanchez, J., Gomez, I., Tabashnik, B.E., Bravo, A., Soberon, M.. ABCC2 is associated with Bacillus thuringiensis Cry1Ac toxin oligomerization and membrane insertion in diamondback moth.
Scientific Reports,
7 (1),
2386.
Artículo; Actas Paper
415 - Onofre, J., Gaytan, M.O., Pena-Cardena, A., Garcia-Gomez, B.I., Pacheco, S., Gomez, I., Bravo, A., Soberon, M.. Identification of Aminopeptidase-N2 as a Cry2Ab binding protein in Manduca sexta.
Peptides,
98,
93-98.
Artículo
416 - Pacheco, S., Gomez, I., Sanchez, J., Garcia-Gomez, B.I., Soberon, M., Bravo, A.. Intra-molecular salt bridge in Bacillus thuringiensis Cry4Ba toxin is involved in the stability of helix alpha-3 that is needed for oligomerization and insecticidal activity.
Applied and Environmental Microbiology,
83 (20),
e01515-e01517.
Artículo
417 - Portugal, L., Munoz-Garay, C., Martinez-deCastro, D.L., Soberon, M., Bravo, A.. Toxicity of Cry1A toxins from Bacillus thuringiensis to CF1 cells does not involve activation of adenylate cyclase/PKA signaling pathway.
Insect Biochemistry and Molecular Biology,
80,
21-31.
Artículo
418 - Rubio, V.P., Bravo, A., Olmos, J.. Identification of a Bacillus thuringiensis Surface-Layer-Protein with Cytotoxic Activity against MDA-MB-231 Breast Cancer Cells.
Journal of Microbiology and Biotechnology,
27 (1),
36-42.
Artículo
419 - Xiao, Y., Dai, Q., Hu, R., Pacheco, S., Yang, Y., Liang, G., Soberon, M., Bravo, A., Liu, K., Wu, K.. A Single Point Mutation Resulting in Cadherin Mis-localization Underpins Resistance against Bacillus thuringiensis Toxin in Cotton Bollworm.
Journal of Biological Chemistry,
292 (7),
2933-2943.
Artículo
420 - Zhou, Z., Liu, Y., Liang, G., Huang, Y., Bravo, A., Soberon, M., Song, F., Zhou, X., Zhang, J.. Insecticidal specificity of Cry1Ah to Helicoverpa armigera is determined by binding APN1 through domain II loops 2 and 3.
Applied and Environmental Microbiology,
83 (4),
e02864-16.
Internacional
421 - Bravo, A., Pacheco, S., Gomez, I., Garcia-Gomez, B., Onofre, J., Soberon, M.. Insecticidal Proteins from Bacillus thuringiensis and Their Mechanism of Action. Bacillus thuringiensis and Lysinibacillus sphaericus: Characterization and use in the field of biocontrol.
53-66,
Cham: Springer.
Artículo
422 - Fang,L., Wang,B., Zhou,Z., Yang,S., Shu,C., Song,F., Bravo,A., Soberon,M., Zhang,J.. Oligomerization of Cry9Aa in solution without receptor binding, is not related with insecticidal activity.
Electronic Journal of Biotechnology,
21,
54-57.
Artículo
423 - Jin,T., Duan,X., Bravo,A., Soberon,M., Wang,Z., He,K.. Identification of an alkaline phosphatase as a putative Cry1Ac binding protein in Ostrinia furnacalis (Gun?e).
Pesticide Biochemistry And Physiology,
131,
80-86.
Artículo
424 - Queiroz,P.R., Ramiro,C.A., Martins,E.S., Soberon,M., Bravo,A., Monnerat,R.G.. Mitochondrial markers to distinguish Spodoptera frugiperda populations associated with corn and cotton crops.
Pesquisa Agropecuaria Brasileira,
51 (5),
692-696.
Artículo
425 - Wang,Y., Wang,Y., Wang,Z., Bravo,A., Soberon,M., He,K.. Genetic Basis of Cry1F-Resistance in a Laboratory Selected Asian Corn Borer Strain and Its Cross-Resistance to Other Bacillus thuringiensis Toxins.
PLoS ONE,
11 (8),
e0161189.
Artículo
426 - Xiao,Y., Liu,K., Zhang,D., Gong,L., He,F., Soberon,M., Bravo,A., Tabashnik,B.E., Wu,K.. Resistance to Bacillus thuringiensis Mediated by an ABC Transporter Mutation Increases Susceptibility to Toxins from Other Bacteria in an Invasive Insect.
PLoS Pathogens,
12 (2),
e1005450.
Artículo
427 - Zhang,D., Xiao,Y., Hussain,Dhiloo K., Soberon,M., Bravo,A., Wu,K.. Molecular Cloning, Expression, and Identification of Bre Genes Involved in Glycosphingolipids Synthesis in Helicoverpa armigera (Lepidoptera: Noctuidae).
Journal Of Economic Entomology,
109 (3),
1415-1423.
Artículo
428 - Zhou,Z., Wang,Z., Liu,Y., Liang,G., Shu,C., Song,F., Zhou,X., Bravo,A., Soberon,M., Zhang,J.. Identification of ABCC2 as a binding protein of Cry1Ac on brush border membrane vesicles from Helicoverpa armigera by an improved pull-down assay.
Microbiologyopen,
5 (4),
659-669.
Internacional
429 - Soberon,M., Bravo,A., Blanco,C.A.. Strategies to Reduce Insecticide Use in Agricultural Production. Reference Module in Food Science. .
Internacional
430 - Soberon,M., Monnerat,R., Bravo,A.. Mode of Action of Cry Toxins from Bacillus thuringiensis and Resistance Mechanisms. Microbial Toxins.
1-13,
Dordrecht.
Artículo
431 - Canton,P.E., Cancino-Rodezno,A., Gill,S.S., Soberon,M., Bravo,A.. Transcriptional cellular responses in midgut tissue of Aedes aegypti larvae following intoxication with Cry11Aa toxin from Bacillus thuringiensis.
BMC Genomics,
16 (1),
1042.
Artículo
432 - Chavez,C., Recio-Totoro,B., Flores-Escobar,B., Lanz-Mendoza,H., Sanchez,J., Soberon,M., Bravo,A.. Nitric oxide participates in the toxicity of Bacillus thuringiensis Cry1Ab toxin to kill Manduca sexta larvae.
Peptides,
68,
134-139.
Artículo
433 - Garcia,K., Ibarra,J.E., Bravo,A., Diaz,J., Gutierrez,D., Torres,P.V., Gomez de Leon P.. Variability of Bacillus thuringiensis Strains by ERIC-PCR and Biofilm Formation.
Current Microbiology,
70 (1),
10-18.
Artículo
434 - Gomez,I., Flores,B., Bravo,A., Soberon,M.. Bacillus thuringiensis Cry1AbMod toxin counters tolerance associated with low cadherin expression but not that associated with low alkaline phosphatase expression in Manduca sexta.
Peptides,
68 (1),
130-133.
Artículo
435 - Monnerat,R., Martins,E., Macedo,C., Queiroz,P., Praca,L., Soares,C.M., Moreira,H., Grisi,I., Silva,J., Soberon,M., Bravo,A.. Evidence of Field-Evolved Resistance of Spodoptera frugiperda to Bt Corn Expressing Cry1F in Brazil That Is Still Sensitive to Modified Bt Toxins.
PLoS ONE,
10 (4),
e0119544.
Artículo
436 - Ocelotl,J., Sanchez,J., Arroyo,R., Garcia-Gomez,B.I., Gomez,I., Unnithan,G.C., Tabashnik,B.E., Bravo,A., Soberon,M.. Binding and Oligomerization of Modified and Native Bt Toxins in Resistant and Susceptible Pink Bollworm.
PLoS ONE,
10 (12),
e0144086.
Artículo
437 - Pacheco,S., Canton,E., Zuniga-Navarrete,F., Pecorari,F., Bravo,A., Soberon,M.. Improvement and efficient display of Bacillus thuringiensis toxins on M13 phages and ribosomes.
AMB Express,
5 (1),
73.
Artículo
438 - Shu,C., Tan,S., Yin,J., Soberon,M., Bravo,A., Liu,C., Geng,L., Song,F., Li,K., Zhang,J.. Assembling of Holotrichia parallela (dark black chafer) midgut tissue transcriptome and identification of midgut proteins that bind to Cry8Ea toxin from Bacillus thuringiensis.
Applied Microbiology and Biotechnology,
99 (17),
7209-7218.
Artículo
439 - Tabashnik,B.E., Zhang,M., Fabrick,J.A., Wu,Y., Gao,M., Huang,F., Wei,J., Zhang,J., Yelich,A., Unnithan,G.C., Bravo,A., Soberon,M., Carriere,Y., Li,X.. Dual mode of action of Bt proteins: protoxin efficacy against resistant insects.
Scientific Reports,
5,
15107.
Artículo
440 - Zuniga-Navarrete,F., Gomez,I., Pena,G., Amaro,I., Ortiz,E., Becerril,B., Ibarra,J.E., Bravo,A., Soberon,M.. Identification of Bacillus thuringiensis Cry3Aa toxin domain II loop 1 as the binding site of Tenebrio molitor cadherin repeat CR12.
Insect Biochemistry and Molecular Biology,
59,
50-57.
Internacional
441 - Bravo, A., Martinez-de-Castro, D. L., Sanchez-Quintana, J., Canton, P. E., Mendoza, G., Gomez, I., Pacheco, S., Garcia-Gomez, B. I., Onofre, J., Ocelotl, J., Soberon, M.. Mechanism of action of Bacillus thuringiensis insecticidal toxins and their use in the control of insect pests. Comprehensive Sourcebook of Bacterial Protein Toxins.
858-873,
4a ed.
Internacional
442 - Bravo,A., Gomez,I., Mendoza,G., Gaytan,M., Soberon,M.. Different models of the mode of action of Bt 3d-Cry toxins. Bt resistance - characterization and strategies for GM crops expressing Bacillus thuringiensis toxins.
56-68,
Oxford.
Editorial Material
443 - Bravo,A., Soberon,M., Gao,Y.. Preface. Bt Resistance: Characterization and Strategies for GM Crops Producing Bacillus thuringiensis Toxins.
xi-xii,
Oxford.
Internacional
444 - Soberon,M., Garcia-Gomez,B.I., Pacheco,S., Sanchez-Quintana,J., Tabashnik,B.E., Bravo,A.. Countering pest resistance with genetically modified Bt toxins. Bt resistance-characterization and strategies for GM crops expressing Bacillus thuringiensis.
CABI Biotechnology Series Volume: 4,
150-161,
Oxford.
Internacional
445 - Soberon, M., Gao, Y. L., Bravo, A.. Bt resistance- characterization and strategies for GM crops expressing Bacillus thuringiensis toxins.
CABI Biotechnology Series,
1-213,
Oxford: CABI.
Divulgación
446 - Bravo-de-la-Parra,A.. Viejas y nuevas tendencias en el uso de la fluorescencia para el analisis estructural de las proteínas y sus procesos.
Biotecnología en Movimiento. Revista de divulgación del Instituto de Biotecnología de la UNAM,
1,
26.
Artículo
447 - Canton,P.E., Lopez-Diaz,J.A., Gill,S.S., Bravo,A., Soberon,M.. Membrane binding and oligomer membrane insertion are necessary but insufficient for Bacillus thuringiensis Cyt1Aa toxicity.
Peptides,
53,
286-291.
Artículo
448 - Gomez,I., Sanchez,J., Munoz-Garay,C., Matus,V., Gill,S.S., Soberon,M., Bravo,A.. Bacillus thuringiensis Cry1A toxins are versatile-proteins with multiple modes of action: two distinct pre-pores are involved in toxicity.
Biochemical Journal,
459 (2),
383-396.
Artículo
449 - Monnerat,R., Pereira,E., Teles,B., Martins,E., Praca,L., Queiroz,P., Soberon,M., Bravo,A., Ramos,F., Soares,C.M.. Synergistic activity of Bacillus thuringiensis toxins against Simulium spp. larvae.
Journal of Invertebrate Pathology,
121,
70-73.
Artículo
450 - Portugal,L., Gringorten,J.L., Caputo,G.F., Soberon,M., Munoz-Garay,C., Bravo,A.. Toxicity and mode of action of insecticidal Cry1A proteins from Bacillus thuringiensis in an insect cell line, CF-1.
Peptides,
53,
292-299.
Memoria in extenso
451 - Bravo,A., Martinez-de-Castro,D.L., Sanchez,J., Munoz-Garay,C., Matus,V., Canton,P.E., Lopez-Diaz,J., Portugal,L., Mendoza,G., Soberon,M.. Mode of action of Bacillus thuringiensis toxins and their use in transgenic crops to control insect pests. Biotechnology: beyond borders.
Proceedings of the Indo-Mexico workshop on Biotechnology held at CSIR NCL, Pune, India from October 7-9, 2013.,
122-134.
Memoria in extenso
452 - Soberon,M., Gomez,I., Garcia-Gomez,B.I., Carmona,D., Ocelotl,J., Villanueva,F., Flores,B., Bravo,A.. Mode of action of mosquitocidal toxins from Bacillus thuringiensis and their use in control of insect vectors of human diseases. Biotechnology: beyond borders.
Proceedings of the Indo-Mexico workshop on Biotechnology held at CSIR NCL, Pune, India from October 7-9, 2013.,
279-288.
Artículo
453 - Bedoya-Perez,L.P., Cancino-Rodezno,A., Flores-Escobar,B., Soberon,M., Bravo,A.. Role of UPR Pathway in Defense Response of Aedes aegypti against Cry11Aa Toxin from Bacillus thuringiensis.
International Journal of Molecular Sciences,
14 (4),
8467-8478.
Artículo
454 - Bravo,A.. Biotecnología agrícola y agroecologia, complementarias u opuestas?.
Ciencia, Revista de la Academia Mexicana de Ciencia,
64 (1),
68-77.
Revisión
455 - Bravo,A., Gomez,I., Porta,H., Garcia-Gomez,B.I., Rodriguez-Almazan,C., Pardo,L., Soberon,M.. Evolution of Bacillus thuringiensis Cry toxins insecticidal activity.
Microbial Biotechnology,
6 (1),
17-26.
Artículo
456 - Flores-Escobar,B., Rodriguez-Magadan,H., Bravo,A., Soberon,M., Gomez,I.. Differential role of Manduca sexta aminopeptidase-N and alkaline phosphatase in the mode of action of Cry1Aa, Cry1Ab, and Cry1Ac toxins from Bacillus thuringiensis.
Applied and Environmental Microbiology,
79 (15),
4543-4550.
Artículo
457 - Garcia-Gomez,B.I., Sanchez,J., Martinez de Castro,D.L., Ibarra,J.E., Bravo,A., Soberon,M.. Efficient production of Bacillus thuringiensis Cry1AMod toxins under regulation of cry3Aa promoter and single cysteine mutations in the protoxin region.
Applied and Environmental Microbiology,
79 (22),
6969-6973.
Artículo
458 - Lopez-Diaz,J.A., Canton,P.E., Gill,S.S., Soberon,M., Bravo,A.. Oligomerization is a key step in Cyt1Aa membrane insertion and toxicity but not necessary to synergize Cry11Aa toxicity in Aedes aegypti larvae.
Environmental Microbiology,
15 (11),
3030-3039.
Revisión
459 - Pardo-Lopez,L., Soberon,M., Bravo,A.. Bacillus thuringiensis insecticidal 3-domain Cry toxins: Mode of action, insect resistance and consequences for crop protection.
FEMS Microbiology Reviews,
37 (1),
3-22.
Revisión
460 - Soberon,M., Lopez-Diaz,J.A., Bravo,A.. Cyt toxins produced by Bacillus thuringiensis: A protein fold conserved in several pathogenic microorganisms.
Peptides,
41,
87-93.
Artículo
461 - Tabashnik,B.E., Fabrick,J.A., Unnithan,G.C., Yelich,A.J., Masson,L., Zhang,J., Bravo,A., Soberon,M.. Efficacy of Genetically Modified Bt Toxins Alone and in Combinations Against Pink Bollworm Resistant to Cry1Ac and Cry2Ab.
PLoS ONE,
8 (11),
e80496.
Artículo; Actas Paper
Artículo
463 - Cancino-Rodezno,A., Lozano,L., Oppert,C., Castro,J.I., Lanz-Mendoza,H., Encarnacion,S., Evans,A.E., Gill,S.S., Soberon,M., Jurat-Fuentes,J.L., Bravo,A.. Comparative Proteomic Analysis of Aedes aegypti Larval Midgut after Intoxication with Cry11Aa Toxin from Bacillus thuringiensis.
PLoS ONE,
7 (5),
e37034.
Artículo
464 - Jimenez,A.I., Reyes,E.Z., Cancino-Rodezno,A., Bedoya-Perez,L.P., Caballero-Flores,G.G., Muriel-Millan,L.F., Likitvivatanavong,S., Gill,S.S., Bravo,A., Soberon,M.. Aedes aegypti alkaline phosphatase ALP1 is a functional receptor of Bacillus thuringiensis Cry4Ba and Cry11Aa toxins.
Insect Biochemistry and Molecular Biology,
42 (9),
683-689.
Artículo
465 - Rodriguez-Almazan,C., Reyes,E.Z., Zuniga-Navarrete,F., Munoz-Garay,C., Gomez,I., Evans,A.M., Likitvivatanavong,S., Bravo,A., Gill,S.S., Soberon,M.. Cadherin binding is not a limiting step for Bacillus thuringiensis subs. israelensis Cry4Ba toxicity to Aedes aegypti larvae.
Biochemical Journal,
443,
711-717.
Artículo
466 - Soberon,M., Rodriguez-Almazan,C., Munoz-Garay,C., Pardo-Lopez,L., Porta,H., Bravo,A.. Bacillus thuringiensis Cry and Cyt mutants useful to counter toxin action in specific environments and to overcome insect resistance in the field.
Pesticide Biochemistry And Physiology,
104 (2),
111-117.
Revisión
467 - Vazquez-Pineda,A., Bravo-de-la-Parra,A., Mendoza de Gives,P., Liebano-Hernandez,E., Hernandez-Linares,I, Yanez-Perez,N., Aguilar-Marcelino,L., Ramirez-Vargas,G., Hernandez-Castro,E., Gutierrez-Segura,I., Lopez-Arellano,E.. Use of Bacillus thuringiensis products as alternative method of control against important veterinary parasitic nematodes : Review.
Revista Mexicana de Ciencias Pecuarias,
3 (1),
77-88.
Internacional
468 - Zuniga-Navarrete,F., Bravo,A., Soberon,M., Gomez,I.. Role of GPI-anchored membrane receptors in the mode of action of Bacillus thuringiensis Cry toxins. Integrated Pest Management and Pest Control- Current and Future Tactics.
551-566.
Revisión
469 - Bravo,A., Likitvivatanavong,S., Gill,S.S., Soberon,M.. Bacillus thuringiensis: A story of a successful bioinsecticide.
Insect Biochemistry and Molecular Biology,
41 (7),
423-431.
Artículo
470 - Canton,P.E., Reyes,E.Z., Escudero,I.R., Bravo,A., Soberon,M.. Binding of Bacillus thuringiensis subsp. israelensis Cry4Ba to Cyt1Aa has an important role in synergism.
Peptides,
32 (3),
595-600.
Artículo
471 - Carmona,D., Rodriguez-Almazan,C., Munoz-Garay,C., Portugal,L., Perez,C., de Maagd,R.A., Bakker,P., Soberon,M., Bravo,A.. Dominant Negative Phenotype of Bacillus thuringiensis Cry1Ab, Cry11Aa and Cry4Ba Mutants Suggest Hetero-Oligomer Formation among Different Cry Toxins.
PLoS ONE,
6 (5),
e19952.
Artículo
472 - Likitvivatanavong,S., Chen,J., Evans,A.M., Bravo,A., Soberon,M., Gill,S.S.. Multiple Receptors as Targets of Cry Toxins in Mosquitoes.
Journal of Agricultural and Food Chemistry,
59 (7),
2829-2838.
Artículo
473 - Likitvivatanavong,S., Chen,J., Bravo,A., Soberon,M., Gill,S.S.. Cadherin, Alkaline Phosphatase, and Aminopeptidase N as Receptors of Cry11Ba Toxin from Bacillus thuringiensis subsp. jegathesan in Aedes aegypti?.
Applied and Environmental Microbiology,
77 (1),
24-31.
Artículo
474 - Porta,H., Munoz-Minutti,C., Soberon,M., Bravo,A.. Induction of Manduca sexta Larvae Caspases Expression in Midgut Cells by Bacillus thuringiensis Cry1Ab Toxin.
Psyche: A Journal of Entomology,
Article ID 938249.
Artículo
475 - Porta,H., Jimenez,G., Cordoba,E., Leon,P., Soberon,M., Bravo,A.. Tobacco plants expressing the Cry1AbMod toxin suppress tolerance to Cry1Ab toxin of Manduca sexta cadherin-silenced larvae.
Insect Biochemistry and Molecular Biology,
41 (7),
513-519.
Revisión
476 - Porta,H., Cancino-Rodezno,A., Soberon,M., Bravo,A.. Role of MAPK p38 in the cellular responses to pore-forming toxins.
Peptides,
32 (3),
601-606.
Artículo
477 - Rodriguez-Almazan,C., Ruiz de Escudero,I, Canton,P.E., Munoz-Garay,C., Perez,C., Gill,S.S., Soberon,M., Bravo,A.. The amino- and carboxyl-terminal fragments of the Bacillus thuringiensis Cyt1Aa toxin have differential roles on toxin oligomerization and pore formation.
Biochemistry,
50 (3),
388-396.
Artículo
478 - Tabashnik,B.E., Huang,F., Ghimire,M.N., Leonard,B.R., Siegfried,B.D., Rangasamy,M., Yang,Y., Wu,Y., Gahan,L.J., Heckel,D.G., Bravo,A., Soberon,M.. Efficacy of genetically modified Bt toxins against insects with different genetic mechanisms of resistance.
Nature Biotechnology,
29,
1128-1131.
Revisión
479 - Terenius,O., Papanicolaou,A., Garbutt,J.S., Eleftherianos,I., Huvenne,H., Sriramana,K., Albrechtsen,M., An,C., Aymeric,J.L., Barthel,A., Bebas,P., Bitra,K., Bravo,A., Chevalier,F., Collinge,D.P., Crava,C.M., de Maagd,R.A., Duvic,B., Erlandson,M., Faye,I., Felfoldi,G., Fujiwara,H., Futahashi,R., Gandhe,A.S., Gatehouse,H.S., Gatehouse,L.N., Giebultowicz,J., Gomez,I., Grimmelikhuijzen,C.J., Groot,A.T., Hauser,F., Heckel,D.G., Hegedus,D.D., Hrycaj,S., Huang,L., Hull,J.J., Iatrou,K., Iga,M., Kanost,M.R., Kotwica,J., Li,C., Li,J., Liu,J., Lundmark,M., Matsumoto,S., Meyering-Vos,M., Millichap,P.J., Monteiro,A., Mrinal,N., Niimi,T., Nowara,D., Ohnishi,A., Oostra,V., Ozaki,K., Papakonstantinou,M., Popadic,A., Rajam,M.V., Saenko,S., Simpson,R.M., Soberon,M., Strand,M.R., Tomita,S., Toprak,U., Wang,P., Wee,C.W., Whyard,S., Zhang,W., Nagaraju,J., Ffrench-Constant,R.H., Herrero,S., Gordon,K., Swevers,L., Smagghe,G., et al. RNA interference in Lepidoptera: an overview of successful and unsuccessful studies and implications for experimental design.
Journal of Insect Physiology,
57 (2),
231-245.
Artículo
480 - Zavala,L.E., Pardo-Lopez,L., Canton,P.E., Gomez,I., Soberon,M., Bravo,A.. Domains II and III of Bacillus thuringiensis Cry1Ab toxin remain exposed to the solvent after insertion of part of domain I into the membrane.
Journal of Biological Chemistry,
286 (21),
19109-19117.
Internacional
481 - Bravo,A., del Rincon-Castro,M.C., Ibarra,J.E., Soberon,M.. Towards a healthy control of insect pest: Potential use of Microbial insecticides. Green trends in insect control.
266-299,
London.
Nacional
482 - Soberon,M., Bravo,A.. Control de insectos con Bacillus thuringiensis, un método efectivo y compatible con el ambiente. V CICLO MUJER CIENCIA.
1-11,
Mexico,D.F:.
Artículo
483 - Arenas,I., Bravo,A., Soberon,M., Gomez,I.. Role of alkaline phosphatase from Manduca sexta in the mechanism of action of Bacillus thuringiensis Cry1Ab toxin.
Journal of Biological Chemistry,
285 (17),
12497-503.
Artículo
484 - Cancino-Rodezno,A., Alexander,C., Villasenor,R., Pacheco,S., Porta,H., Pauchet,Y., Soberon,M., Gill,S.S., Bravo,A.. The mitogen-activated protein kinase p38 is involved in insect defense against cry toxins from Bacillus thuringiensis.
Insect Biochemistry and Molecular Biology,
40 (1),
58-63 [corrigendum 43 (9) 898 2013 ].
Artículo
485 - Fernandez-Luna,M.T., Tabashnik,B.E., Lanz-Mendoza,H., Bravo,A., Soberon,M., Miranda-Rios,J.. Single concentration tests show synergism among Bacillus thuringiensis subsp. israelensis toxins against the malaria vector mosquito Anophelesalbimanus.
Journal of Invertebrate Pathology,
104 (3),
231-233.
Artículo
486 - Fernandez-Luna,M.T., Lanz-Mendoza,H., Gill,S.S., Bravo,A., Soberon,M., Miranda-Rios,J.. An alpha-amylase is a novel receptor for Bacillus thuringiensis ssp. israelensis Cry4Ba and Cry11Aa toxins in the malaria vector mosquito Anopheles albimanus (Diptera: Culicidae).
Environmental Microbiology,
12 (3),
746-757.
Artículo
487 - Fernandez-Ruvalcaba,M., Pena-Chora,G., Romo-Martinez,A., Hernandez-Velazquez,V., de la Parra,A.B., De la Rosa,D.P.. Evaluation of Bacillus thuringiensis pathogenicity for a strain of the tick, Rhipicephalus microplus, resistant to chemical pesticides - art. no. 186.
Journal of Insect Science,
10,
186-190.
Artículo
488 - Gomez,I., Arenas,I., Pacheco,S., Bravo,A., Soberon,M.. New Insights into the Mode of Action of Cry1Ab Toxin Used in Transgenic Insect-resistant Crops.
Southwestern Entomologist,
35 (3),
387-390.
Artículo
489 - Martins,E.S., Monnerat,R.G., Queiroz,P.R., Dumas,V.F., Braz,S.V., de Souza Aguiar,R.W., Mendes-Gomes,A.C., Sanchez,J., Bravo,A., Ribeiro,B.M.. Midgut GPI- anchored proteins with alkaline phosphatase activity from the cotton boll weevil (Anthonomus grandis) can be the putative receptors for the Cry1B protein of Bacillus thuringiensis.
Insect Biochemistry and Molecular Biology,
40 (2),
138-145.
Artículo
490 - Munoz-Garay,C., Soberon,M., Bravo,A.. Mode of Action of Bacillus thuringiensis-Genetically Modified Cry1AbMod and Cry1AcMod Toxins Role of Alkaline pH in Toxin Oligomerization.
Southwestern Entomologist,
35 (3),
383-386.
Artículo; Actas Paper
491 - Vazquez-Pineda,A., Yanez-Perez,G.N., Lopez-Arellano,M.E., Mendoza de Gives,P., Liebano-Hernandez,E., Bravo-de-la-Parra,A.. Biochemical Characterization of Two Purified Proteins of the IB-16 Bacillus thuringiensis Strains and Their Toxicity Against the Sheep Nematode Haemonchus contortus In vitro.
Transboundary and Emerging Diseases,
57 (1-2),
111-114.
Internacional
492 - Bravo,A., Gill,S.S., Soberon,M.. Bacillus thuringiensis Mechanisms and Use with addendum 2010. Insect Control Biological and Synthetic Agents.
Comprehensive Molecular Insect Science,
247-282.
Internacional
493 - Soberon,M., Pardo,L., Munoz-Garay,C., Sanchez,J., Gomez,I., Porta,H., Bravo,A.. Pore Formation by Cry Toxins. Proteins: Membrane Binding and Pore Formation.
Advances in Experimental Medicine and Biology,
127-142,
Austin, TX: Landes Bioscience.
Revisión
494 - Cancino-Rodezno,A., Porta,H., Soberon,M., Bravo,A.. Defense and death responses to pore forming toxins.
Biotechnology and Genetic Engineering Reviews,
26 (65),
82.
Artículo
495 - Chen,J., Aimanova,K.G., Fernandez,L.E., Bravo,A., Soberon,M., Gill,S.S.. Aedes aegypti cadherin serves as a putative receptor of the Cry11Aa toxin from Bacillus thuringiensis subsp. israelensis.
Biochemical Journal,
424 (2),
191-200.
Artículo
496 - Fernandez,L.E., Martinez-Anaya,C., Lira,E., Chen,J., Evans,A., Hernandez-Martinez,S., Lanz-Mendoza,H., Bravo,A., Gill,S.S., Soberon,M.. Cloning and epitope mapping of Cry11Aa-binding sites in the Cry11Aa-receptor alkaline phosphatase from Aedes aegypti.
Biochemistry,
48 (37),
8899-8907.
Artículo
497 - Franklin,M.T., Nieman,C.L., Janmaat,A.F., Soberon,M., Bravo,A., Tabashnik,B.E., Myers,J.H.. Modified Bacillus thuringiensis toxins and a hybrid B. thuringiensis strain counter greenhouse-selected resistance in Trichoplusia ni.
Applied and Environmental Microbiology,
75 (17),
5739-5741.
Artículo
498 - Munoz-Garay,C., Portugal,L., Pardo-Lopez,L., Jimenez-Juarez,N., Arenas,I., Gomez,I., Sanchez-Lopez,R., Arroyo,R., Holzenburg,A., Savva,C.G., Soberon,M., Bravo,A.. Characterization of the mechanism of action of the genetically modified Cry1AbMod toxin that is active against Cry1Ab-resistant insects.
Biochimica et Biophysica Acta (BBA) - Biomembranes,
1788 (10),
2229-2237.
Artículo
499 - Munoz-Garay,C., Rodriguez-Almazan,C., Aguilar,J.N., Portugal,L., Gomez,I., Saab-Rincon,G., Soberon,M., Bravo,A.. Oligomerization of Cry11Aa from Bacillus thuringiensis has an important role in toxicity against Aedes aegypti.
Applied and Environmental Microbiology,
75 (23),
7548-7550.
Artículo
500 - Pacheco,S., Gomez,I., Gill,S.S., Bravo,A., Soberon,M.. Enhancement of insecticidal activity of Bacillus thuringiensis Cry1A toxins by fragments of a toxin-binding cadherin correlates with oligomer formation.
Peptides,
30 (3),
583-588.
Artículo
501 - Pacheco,S., Gomez,I., Arenas,I., Saab-Rincon,G., Rodriguez-Almazan,C., Gill,S.S., Bravo,A., Soberon,M.. Domain II loop 3 of Bacillus thuringiensis Cry1Ab toxin is involved in a "ping-pong" binding mechanism with Manduca sexta aminopetidase-N and cadherin receptors.
Journal of Biological Chemistry,
284 (47),
32750-32757.
Revisión
502 - Pardo-Lopez,L., Munoz-Garay,C., Porta,H., Rodriguez-Almazan,C., Soberon,M., Bravo,A.. Strategies to improve the insecticidal activity of Cry toxins from Bacillus thuringiensis.
Peptides,
30 (3),
589-595.
Artículo
503 - Rodriguez-Almazan,C., Zavala,L.E., Munoz-Garay,C., Jimenez-Juarez,N., Pacheco,S., Masson,L., Soberon,M., Bravo,A.. Dominant negative mutants of Bacillus thuringiensis Cry1Ab toxin function as anti-toxins: demonstration of the role of oligomerization in toxicity.
PLoS ONE,
4 (5),
e5545 [Erratum 2013 8 (2)].
Revisión
504 - Soberon,M., Gill,S.S., Bravo,A.. Signaling versus punching hole: How do Bacillus thuringiensis toxins kill insect midgut cells?.
Cellular and Molecular Life Sciences,
66 (8),
1337-1349.
Revisión
505 - Bravo,A., Soberon,M.. How to cope with insect resistance to Bt toxins?.
Trends in Biotechnology,
26 (10),
573-579.
Artículo
506 - Fernandez,L.E., Gomez,I., Pacheco,S., Arenas,I., Gill,S.S., Bravo,A., Soberon,M.. Employing phage display to study the mode of action of Bacillus thuringiensis Cry toxins.
Peptides,
29 (2),
324-329.
Artículo
507 - Hernandez-Linares,I, Lopez-Arellano,M.E., Mendoza de Gives,P., Liebano-Hernandez,E., Bravo-de-la-Parra,A.. Lethal activity of two Bacillus thuringiensis strains against Haemonchus contortus histotropic larvae.
Annals of the New York Academy of Sciences,
1149,
164-166.
Artículo
508 - Jimenez-Juarez,N., Munoz-Garay,C., Gomez,I., Gill,S.S., Soberon,M., Bravo,A.. The pre-pore from Bacillus thuringiensis Cry1Ab toxin is necessary to induce insect death in Manduca sexta.
Peptides,
29 (2),
318-323.
Nacional
509 - Bravo,A.. Historia de cómo llegamos a proponer el modelo que describe cómo funcionan las toxinas Cry insecticidas producidas por la bacteria Bacillus thuringiensis. Aportaciones científicas y humanísticas mexicanas en el siglo XX.
92-103,
Mexico.
Nacional
510 - Soberon,M., Bravo,A.. Las toxinas Cry de Bacillus thuringiensis: modo de acción y consecuencias de su aplicación. Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 27.
303-314,
Mexico, D.F..
Revisión
511 - Bravo,A., Gill,S.S., Soberon,M.. Mode of action of Bacillus thuringiensis Cry and Cyt toxins and their potential for insect control.
Toxicon,
49 (4),
423-435.
Artículo; Actas Paper
512 - Gomez,I., Pardo-Lopez,L., Munoz-Garay,C., Fernandez,L.E., Perez,C., Sanchez,J., Soberon,M., Bravo,A.. Role of receptor interaction in the mode of action of insecticidal Cry and Cyt toxins produced by Bacillus thuringiensis.
Peptides,
28 (1),
169-173.
Artículo
513 - Ishikawa,H., Hoshino,Y., Motoki,Y., Kawahara,T., Kitajima,M., Kitami,M., Watanabe,A., Bravo,A., Soberon,M., Honda,A., Yaoi,K., Sato,R.. A system for the directed evolution of the insecticidal protein from Bacillus thuringiensis.
Molecular Biotechnology,
36 (2),
90-101.
Artículo
514 - Jimenez-Juarez,N., Munoz-Garay,C., Gomez,I., Saab-Rincon,G., Damian-Almazo,J.Y., Gill,S.S., Soberon,M., Bravo,A.. Bacillus thuringiensis Cry1Ab mutants affecting oligomer formation are non toxic to Manduca sexta larvae.
Journal of Biological Chemistry,
282 (29),
21222-21229.
Artículo
515 - Ochoa-Campuzano,C., Real,M.D., Martinez-Ramirez,A.C., Bravo,A., Rausell,C.. An ADAM metalloprotease is a Cry3Aa Bacillus thuringiensis toxin receptor.
Biochemical and Biophysical Research Communications,
362 (2),
437-442.
Artículo
516 - Perez,C., Munoz-Garay,C., Portugal,L.C., Sanchez,J., Gill,S.S., Soberon,M., Bravo,A.. Bacillus thuringiensis ssp. israelensis Cyt1Aa enhances activity of Cry11Aa toxin by facilitating the formation of a pre-pore oligomeric structure.
Cellular Microbiology,
9 (12),
2931-2937.
Artículo
517 - Rausell,C., Ochoa-Campuzano,C., Martinez-Ramirez,A.C., Bravo,A., Real,M.D.. A membrane associated metalloprotease cleaves Cry3Aa Bacillus thuringiensis toxin reducing pore formation in Colorado potato beetle brush border membrane vesicles.
Biochimica et Biophysica Acta (BBA) - Biomembranes,
362 (2),
437-442.
Artículo
518 - Sauka,D.H., Sanchez,J., Bravo,A., Benintende,G.B.. Toxicity of Bacillus thuringiensis delta-endotoxins against bean shoot borer (Epinotia aporema Wals.) larvae, a major soybean pest in Argentina.
Journal of Invertebrate Pathology,
94 (2),
125-129.
Artículo
519 - Soberon,M., Pardo-Lopez,L., Lopez,I., Gomez,I., Tabashnik,B.E., Bravo,A.. Engineering Modified Bt Toxins to Counter Insect Resistance.
Science,
318 (5856),
1640-1642 [erratum vol 345 (6198) art num 1256132].
Revisión
520 - Soberon,M., Fernandez,L.E., Perez,C., Gill,S.S., Bravo,A.. Mode of action of mosquitocidal Bacillus thuringiensis toxins.
Toxicon,
49 (5),
597-600.
Memoria in extenso
521 - Gomez,I., Miranda-Rios,J., Arenas,I., Grande,R., Becerril,B., Bravo,A., Soberon,M.. Identification of scFv Molecules that Recognize Loop 3 of Domain II and Domain III of Cry1Ab Toxin from Bacillus thuringiensis. 6th Pacific Rim Conference on the biotechnology of Bacillus thuringiensis and its Environmental Impact.
12-14,
Montreal.
Memoria in extenso
522 - Masson,L., Letowski,J., Bravo,A., Brousseau,R.. Using DNA Microarrays for Assessing Crystal Protein Genes in Bacillus thuringiensis. Proceedings of the 6th Pacific Rim Conference on the Biotechnology of Bacillus thuringiensis and its Environmental Impact.
28-30.
Memoria in extenso
523 - Pardo,L., Gomez,I., Munoz-Garay,C., Jimenez-Juarez,N., Sanchez,J., Perez,C., Soberon,M., Bravo,A.. Oligomer Formation of Different Cry Toxins Indicates that a Pre-Pore is an Essential Intermediate in the Mode of Action of the Three-Domain Cry Family. Proceedings of the 6th Pacific Rim Conference on the Biotechnology of Bacillus thuringiensis and its Environmental Impact.
7-8.
Memoria in extenso
524 - Perez,C., Fernandez,L.E., Sun,J.G., Folch,J.L., Gill,S.S., Soberon,M., Bravo,A.. Cyt1Aa from Bacillus thuringiensis subsp. israelensis Synergizes Cry11Aa Toxin Activity by Functioning as a Membrane-Bound Receptor. Proceedings of the 6th Pacific Rim Conference on the Biotechnology of Bacillus thuringiensis and its Environmental Impact.
9-11.
Memoria in extenso
525 - Soberon,M., Gomez,I., Pardo,L., Munoz,C., Fernandez,L.E., Perez,C., Gill,S.S., Bravo,A.. Important Interactions with membrane Receptors in the Mode of Action of Bacillus thuringiensis Cry toxins. 6th Pacific Rim Conference on the biotechnology of Bacillus thuringiensis and its Environmental Impact , cap 1.
1-6,
Montreal.
Artículo
526 - Fernandez,L.E., Aimanova,K.G., Gill,S.S., Bravo,A., Soberon,M.. A GPI-anchored alkaline phosphatase is a functional midgut receptor of Cry11Aa toxin in Aedes aegypti larvae.
Biochemical Journal,
394 (1),
77-84.
Artículo
527 - Gomez,I., Arenas,I., Benitez,I., Miranda-Rios,J., Becerril,B., Grande,R., Almagro,J.C., Bravo,A., Soberon,M.. Specific epitopes of domains II and IIII of bacillus thuringiensis Cry1Ab toxin involved in the sequential interaction with cadherin and aminopeptidase-N receptors in manduca sexta.
Journal of Biological Chemistry,
281 (45),
34032-34039.
Artículo; Actas Paper
528 - Lopez,M.E., Flores,J., Mendoza,P., Vazquez,V., Liebano,E., Bravo,A., Herrera,D., Godines,E., Vargas,P., Zamudio,F.. Use of Bacillus thuringiensis Toxin as an Alternative Method of Control against Haemonchus contortus.
Annals of the New York Academy of Sciences,
1081,
347-354.
Artículo
529 - Monnerat,R., Martins,E., Queiroz,P., Orduz,S., Jaramillo,G., Benintende,G., Cozzi,J., Real,M.D., Martinez-Ramirez,A., Rausell,C., Ceron,J., Ibarra,J.E., Del Rincon-Castro,M.C., Espinoza,A.M., Meza-Basso,L., Cabrera,L., Sanchez,J., Soberon,M., Bravo,A.. Genetic variability of Spodoptera frugiperda Smith (Lepidoptera: Noctuidae) populations from Latin America is associated with variations in susceptibility to Bacillus thuringiensis Cry toxins.
Applied and Environmental Microbiology,
72 (11),
7029-7035.
Artículo
530 - Munoz-Garay,C., Sanchez,J., Darszon,A., de Maagd,R.A., Bakker,P., Soberon,M., Bravo,A.. Permeability Changes of Manduca sexta Midgut Brush Border Membranes Induced by Oligomeric Structures of Different Cry Toxins.
Journal of Membrane Biology,
212 (1),
61-68 [Erratum: 245 (12) 859].
Artículo
531 - Pacheco,S., Gomez,I., Sato,R., Bravo,A., Soberon,M.. Functional display of Bacillus thuringiensis Cry1Ac toxin on T7 phage.
Journal of Invertebrate Pathology,
92 (1),
45-49.
Artículo
532 - Padilla,C., Pardo-Lopez,L., de la Riva,G., Gomez,I., Sanchez,J., Hernandez,G., Nunez,M.E., Carey,M.P., Dean,D.H., Alzate,O., Soberon,M., Bravo,A.. Role of Tryptophan Residues in Toxicity of Cry1Ab Toxin from Bacillus thuringiensis.
Applied and Environmental Microbiology,
72 (1),
901-907.
Artículo; Actas Paper
533 - Pardo-Lopez,L., Gomez,I., Munoz-Garay,C., Jimenez-Juarez,N., Soberon,M., Bravo,A.. Structural and functional analysis of the pre-pore and membrane-inserted pore of Cry1Ab toxin.
Journal of Invertebrate Pathology,
92 (3),
172-177.
Artículo
534 - Pardo-Lopez,L., Gomez,I., Rausell,C., Sanchez,J., Soberon,M., Bravo,A.. Structural Changes of the Cry1Ac Oligomeric Pre-Pore from Bacillus thuringiensis Induced by N-Acetylgalactosamine Facilitates Toxin Membrane Insertion.
Biochemistry,
45 (34),
10329-10336.
Artículo
535 - Pena,G., Miranda-Rios,J., de la Riva,G., Pardo-Lopez,L., Soberon,M., Bravo,A.. A Bacillus thuringiensis S-Layer Protein Involved in Toxicity against Epilachna varivestis (Coleoptera: Coccinellidae).
Applied and Environmental Microbiology,
72 (1),
353-360.
Nacional
536 - Munoz,R., Pardo,L., Sanchez-Quintana,J., Raussell.C., Soberon,M., Bravo,A.. Mecanismos moleculares de insercion de la toxina Cry de Bacillus thuringiensis en membrana. La fisica biologica en Mexico.
1-27,
Mexico.
Nacional
537 - Ibarra,J.E., Castro,M.C., Galindo,E., Patino,M., Serrano,L., Garcia,R., Carrillo,J.A., Pereyra-Alferez,B., Alcazar-Pizana,A., Luna-Olvera,H., Galan-Wong,L., Pardo,L., Munoz-Garay,C., Gomez,I., Soberon,M., Bravo,A.. [Microorganisms in the biological control of insects and phytopathogens].
Revista Latinoamericana de Microbiologia,
48 (2),
113-120.
Carta
538 - de Maagd,R.A., Bravo,A., Crickmore,N.. Bt toxin not guilty by association.
Nature Biotechnology,
23 (7),
791.
Artículo
539 - Fernandez,L.E., Perez,C., Segovia,L., Rodriguez,M.H., Gill,S.S., Bravo,A., Soberon,M.. Cry11Aa toxin from Bacillus thuringiensis binds its receptor in Aedes aegypti mosquito larvae through loop alpha-8 of domain II.
FEBS Letters,
579 (17),
3508-3514.
Artículo
540 - Letowski,J., Bravo,A., Brousseau,R., Masson,L.. Assessment of cry1 Gene Contents of Bacillus thuringiensis Strains by Use of DNA Microarrays.
Applied and Environmental Microbiology,
71 (9),
5391-5398.
Artículo
541 - Perez,C., Fernandez,L.E., Sun,J., Folch,J.L., Gill,S.S., Soberon,M., Bravo,A.. Bacillus thuringiensis subsp. israelensis Cyt1Aa synergizes Cry11Aa toxin by functioning as a membrane-bound receptor.
Proceedings of the National Academy of Sciences of the United States of America,
102 (51),
18303-18308.
Artículo
542 - Xie,R., Zhuang,M., Ross,L.S., Gomez,I., Oltean,D.I., Bravo,A., Soberon,M., Gill,S.S.. Single amino acid mutations in the cadherin receptor from heliothis virescens affect its toxin binding ability to Cry1A toxins.
Journal of Biological Chemistry,
280 (9),
8416-8425.
Internacional
543 - Bravo,A., Soberon,M., Gill,S.S.. Bacillus thuringiensis, mechanism and use. Comprehensive molecular insect science.
175-205.
Artículo
544 - Bravo,A., Gomez,I., Conde,J., Munoz-Garay,C., Sanchez,J., Miranda,R., Zhuang,M., Gill,S.S., Soberon,M.. Oligomerization triggers binding of a Bacillus thuringiensis Cry1Ab pore-forming toxin to aminopeptidase N receptor leading to insertion into membrane microdomains.
Biochimica et Biophysica Acta (BBA) - Biomembranes,
1667 (1),
38-46.
Artículo
545 - da Silva,S.M.B., Silva-Werneck,J.O., Falcao,R., Gomes,A.C., Fragoso,R.R., Quezado,M.T., Neto,O.B.O., Aguiar,J.B., de Sa,M.F.G., Bravo,A., Monnerat,R.G.. Characterization of novel Brazilian Bacillus thuringiensis strains active against Spodoptera frugiperda and other insect pests.
Journal of Applied Entomology,
128 (2),
102-107.
Artículo
546 - Rausell,C., Pardo-Lopez,L., Sanchez,J., Munoz-Garay,C., Morera,C., Soberon,M., Bravo,A.. Unfolding events in the water-soluble monomeric Cry1Ab toxin during transition to oligomeric pre-pore and to membrane inserted pore channel.
Journal of Biological Chemistry,
279 (53),
55168-55175.
Artículo
547 - Rausell,C., Munoz-Garay,C., Miranda-CassoLuengo,R., Gomez,I., Rudino-Pinera,E., Soberon,M., Bravo,A.. Tryptophan Spectroscopy Studies and Black Lipid Bilayer Analysis Indicate that the Oligomeric Structure of Cry1Ab Toxin from Bacillus thuringiensis Is the Membrane-Insertion Intermediate.
Biochemistry,
43 (1),
166-174.
Artículo
548 - Rausell,C., Garcia-Robles,I., Sanchez,J., Munoz-Garay,C., Martinez-Ramirez,A.C., Real,M.D., Bravo,A.. Role of toxin activation on binding and pore formation activity of the Bacillus thuringiensis Cry3 toxins in membranes of Leptinotarsa decemlineata (Say).
Biochimica et Biophysica Acta (BBA) - Biomembranes,
1660 (1-2),
99-105.
Artículo
549 - Vazquez-Padron,R.I., de la Riva,G., Silva,Y., Pham,S.M., Soberon,M., Bravo,A., Aitouche,A.. Cryptic endotoxic nature of Bacillus thuringiensis Cry1Ab insecticidal crystal protein.
FEBS Letters,
570 (1-3),
30-36.
Internacional
550 - Soberon,M., Nuñez,M., Gomez I., Sanchez-Quintana,J., Bravo,A.. Functional studies of helix a-5 region from Bacillus thuringiensis Cry1Ab d-endotoxin shows that conserved residues are important for pore formation and stability but not for oligomer formation. Pore-forming peptides and protein toxins.
Cellular and molecular mechanisms of toxin action ;v. 5,
90-101,
London ;New York.
Revisión
551 - de Maagd,R.A., Bravo,A., Berry,C., Crickmore,N., Schnepf,H.E.. Structure, diversity, and evolution of protein toxins from spore-forming entomopathogenic bacteria.
Annual Review of Genetics,
37,
409-433.
Artículo
552 - Gomez,I., Dean,D.H., Bravo,A., Soberon,M.. Molecular Basis for Bacillus thuringiensis Cry1Ab Toxin Specificity: Two Structural Determinants in the Manduca sexta Bt-R(1) Receptor Interact with Loops alpha-8 and 2 in Domain II of Cy1Ab Toxin.
Biochemistry,
42 (35),
10482-10489.
Artículo
553 - Ibarra,J.E., Del Rincon,M.C., Orduz,S., Noriega,D., Benintende,G., Monnerat,R., Regis,L., De Oliveira,C.M., Lanz,H., Rodriguez,M.H., Sanchez,J., Pena,G., Bravo,A.. Diversity of Bacillus thuringiensis Strains from Latin America with Insecticidal Activity against Different Mosquito Species.
Applied and Environmental Microbiology,
69 (9),
5269-5274.
Nacional
554 - Ibarra,A, Soberon,M., Bravo,A.. La biotecnología y el control biológico de insectos. Fronteras de la Biología en los Inicios del Siglo XXI, Módulo III.
27-52,
Mexico,D.F..
Nacional
555 - Nunez-Valdez,M.E., Ramírez-Gama,R.M., Calderon,M.A., Hernandez,L., Romero.A., Rodríguez-Segura,Z., Aranda,E., Bravo,A., Villalobos-Hernandez,F.J.. Bacterias entomopatógenas para el control de larvas de Phyllophaga spp. Estudios Sobre Coleópteros del Suelo en América.
347-359,
Puebla.
Artículo
556 - Bravo,A., Sanchez,J., Kouskoura,T., Crickmore,N.. N-terminal activation is an essential early step in the mechanism of action of the B. thuringiensis Cry1Ac insecticidal toxin.
Journal of Biological Chemistry,
277 (27),
23985-23987.
Artículo
557 - Bravo,A., Miranda,R., Gomez,I., Soberon,M.. Pore formation activity of Cry1Ab toxin from Bacillus thuringiensis in an improved membrane vesicle preparation from Manduca sexta midgut cell microvilli.
1562 (1-2),
63-69.
Artículo
558 - Gomez,I., Sanchez,J., Miranda,R., Bravo,A., Soberon,M.. Cadherin-like receptor binding facilitates proteolytic cleavage of helix alpha-1 in domain I and oligomer pre-pore formation of Bacillus thuringiensis Cry1Ab toxin.
FEBS Letters,
513 (2-3),
242-246.
Artículo
559 - Gomez,I., Miranda-Rios,J., Rudino-Pinera,E., Oltean,D.I., Gill,S.S., Bravo,A., Soberon,M.. Hydropathic complementarity determines interaction of epitope 869HITDTNNK876 in Manduca sexta Bt-R1 receptor with loop 2 of domain II of Bacillus thuringiensis Cry1A toxins.
Journal of Biological Chemistry,
277 (33),
30137-30143.
Artículo
560 - Lopez-Arellano,M.E., Flores-Crespo,J., Mendoza de Gives,P., Bravo-de-la-Parra,A., Herrera-Rodriguez,D, Liebano-Hernandez,E., Vazquez-Prats,V.M., Vargas-Uriostegui,P.. In vitro lethal activity of Bacillus thuringiensis toxins against Haemonchus contortus eggs and infective larvae.
International Journal of Nematology,
12 (1),
66-72.
Artículo
561 - Miranda,R., Gomez,I., Soberon,M., Bravo,A.. Mecanismo de accion de las toxinas Cry de Bacillus Thuringiensis.
TIP revista especializada en Ciencias Quimico-Biologicas,
5,
5-13.
Artículo
562 - Zhuang,M., Oltean,D.I., Gomez,I., Pullikuth,A.K., Soberon,M., Bravo,A., Gill,S.S.. Heliothis virescens and Manduca sexta lipid rafts are involved in Cry1A toxin binding to the midgut epithelium and subsequent pore formation.
Journal of Biological Chemistry,
277 (16),
13863-13872.
563 - Bravo de la Parra, Ma Alejandra. Estrategias moleculares que tiene Rhizobium phaseoli para manejar el nitrogeno en vida libre.
Licenciatura en Investigacion Biomedica Basica,
UNAM.
*
Asesor: Mora, Jaime
Revisión
564 - de Maagd,R.A., Bravo,A., Crickmore,N.. How Bacillus thuringiensis has evolved specific toxins to colonize the insect world.
Trends in Genetics,
17 (4),
193-199.
Artículo
565 - Garcia-Robles,I., Sanchez,J., Gruppe,A., Martinez-Ramirez,A.C., Rausell,C., Real,M.D., Bravo,A.. Mode of action of Bacillus thuringiensis PS86Q3 strain in hymenopteran forest pests.
Insect Biochemistry and Molecular Biology,
31 (9),
849-856.
Artículo
566 - Gomez,I., Oltean,D.I., Gill,S., Bravo,A., Soberon,M.. Mapping the epitope in cadherin-like receptors involved in Bacillus thuringiensis Cry1A toxins interaction using phage display.
Journal of Biological Chemistry,
276 (31),
28906-28912.
Artículo
567 - Miranda,R., Zamudio,F.Z., Bravo,A.. Processing of Cry1Ab delta-endotoxin from Bacillus thuringiensis by Manduca sexta and Spodoptera frugiperda midgut proteases: role in protoxin activation and toxin inactivation.
Insect Biochemistry and Molecular Biology,
31 (12),
1155-1163.
Artículo
568 - Nunez-Valdez,M., Sanchez,J., Lina,L., Guereca,L., Bravo,A.. Structural and functional studies of alpha-helix 5 region from Bacillus thuringiensis Cry1Ab delta-endotoxin.
Biochimica et Biophysica Acta (BBA) - Protein Structure And Molecular Enzymology,
1546 (1),
122-131.
Internacional
569 - Bravo,A.. Proteínas insecticidas de Bacillus thuringiensis. Bioinsecticidas: Fundamentos y aplicaciones de Bacillus thuringiensis en el control integrado de plagas.
73-88,
Navarra.
Nacional
570 - Soberon,M., Bravo,A.. Bacillus thuringisensis y sus toxinas insecticidas. Microbios en linea.
221-235.
Nacional
571 - Bravo,A., Arrieta,G, Benintende,G, Real,M.D., Espinoza,A.M., Ibarra.J., Monnerat,R., Orduz,S, Soberon,M.. Metodologías utilizadas en investigación sobre bacterias entimopatógenas.
Mexico, D.F..
Artículo
572 - Soberon,M., Perez,R.V., Nunez-Valdez,M.E., Lorence,A., Gomez,I., Sanchez,J., Bravo,A.. Evidence for intermolecular interaction as a necessary step for pore-formation activity and toxicity of Bacillus thuringiensis Cry1Ab toxin.
Fems Microbiology Letters,
191 (2),
221-225.
Internacional
573 - Monnerat,R., Bravo,A.. Proteinas bioinsecticidas produzidas pela bacteria Bacillus thuringiensis. Contole biologico. .
Artículo
574 - Guereca,L., Bravo,A.. The oligomeric state of Bacillus thuringiensis Cry toxins in solution.
Biochimica et Biophysica Acta (BBA) - Protein Structure And Molecular Enzymology,
1429 (2),
342-350.
Internacional
575 - Bravo,A.. Comparative analysis of pore formation activity of cry toxins in membranes isolated from different insect orders. Biotechnology of Bacillus thuringiensis.
177-178,
Beijing, China..
Divulgación
576 - Aranda,E., Sanchez,J.F., Lina,L., Peferoen,M., Bravo,A.. Analisis de la union in vitro e in vivo de las d-endotoxinas de Bacillus Thuringiensis al epitelio intestinal de Diatrea grandiosello.
BioTecnologia. Sociedad Mexicana de Biotecnologia y Bioingenieria,
3,
95-105.
Artículo
577 - Bravo,A., Sarabia,S., Lopez,L., Ontiveros,H., Abarca,C., Ortiz,A., Ortiz,M., Lina,L., Villalobos,F.J., Pena,G., Nunez-Valdez,M.E., Soberon,M., Quintero,R.. Characterization of cry genes in a Mexican Bacillus thuringiensis strain collection.
Applied and Environmental Microbiology,
64 (12),
4965-4972.
Artículo
578 - Bohorova,N., Cabrera,M., Abarca,C., Quintero,R., Maciel,A.M., Brito,R.M., Hoisington,D., Bravo,A.. Susceptibility of four tropical lepidopteran maize pests to Bacillus thuringiensis CryI-type insecticidal toxins.
Journal Of Economic Entomology,
90 (2),
412-415.
Revisión
579 - Bravo,A.. Phylogenetic relationships of Bacillus thuringiensis delta-endotoxin family proteins and their functional domains.
Journal of Bacteriology,
179 (9),
2793-2801.
Artículo
580 - Flores,H., Soberon,X., Sanchez,J., Bravo,A.. Isolated domain II and III from the Bacillus thuringiensis Cry1Ab delta-endotoxin binds to lepidopteran midgut membranes.
FEBS Letters,
414 (2),
313-318.
Artículo
581 - Lorence,A., Darszon,A., Bravo,A.. Aminopeptidase dependent pore formation of Bacillus thuringiensis Cry1Ac toxin on Trichoplusia ni membranes.
FEBS Letters,
414 (2),
303-307.
Artículo
582 - Aranda,E., Sanchez,J., Peferoen,M., Guereca,L., Bravo,A.. Interactions of Bacillus thuringiensis crystal proteins with the midgut epithelial cells of Spodoptera frugiperda (Lepidoptera: Noctuidae).
Journal of Invertebrate Pathology,
68 (3),
203-212.
Artículo
583 - Bravo,A., Agaisse,H., Salamitou,S., Lereclus,D.. Analysis of cryIAa expression in sigE and sigK mutants of Bacillus thuringiensis.
Molecular and General Genetics,
250 (6),
734-741.
*
Artículo
584 - Meza,R., Nunez-Valdez,M.E., Sanchez,J., Bravo,A.. Isolation of Cry1Ab protein mutants of Bacillus thuringiensis by a highly efficient PCR site-directed mutagenesis system.
Fems Microbiology Letters,
145 (3),
333-339.
Artículo
585 - Salamitou,S., Agaisse,H., Bravo,A., Lereclus,D.. Genetic analysis of cryIIIA gene expression in Bacillus thuringiensis.
Microbiology,
142 (Pt 8),
2049-2055.
*
Artículo
586 - Ceron,J., Ortiz,A., Quintero,R., Guereca,L., Bravo,A.. Specific PCR primers directed to identify cryI and cryIII genes within a Bacillus thuringiensis strain collection.
Applied and Environmental Microbiology,
61 (11),
3826-3831.
Artículo
587 - Lorence,A., Darszon,A., Diaz,C., Lievano,A., Quintero,R., Bravo,A.. Delta-endotoxins induce cation channels in Spodoptera frugiperda brush border membranes in suspension and in planar lipid bilayers.
FEBS Letters,
360 (3),
217-222.
Divulgación
588 - Bravo,A., Lorence,A., Quintero,R.. Biopesticidas compatibles con el medio ambiente: Bacillus thuringiensis, un modelo unico.
Biocontrol,
1 (1),
41-55.
Note
589 - Ceron,J., Covarrubias,L., Quintero,R., Ortiz,A., Ortiz,M., Aranda,E., Lina,L., Bravo,A.. PCR analysis of the cryI insecticidal crystal family genes from Bacillus thuringiensis.
Applied and Environmental Microbiology,
60 (1),
353-356.
Artículo
590 - Guereca,L., Bravo,A., Quintero,R.. Design of an aqueous two-phase system for the purification of ICP from Bacillus thuringiensis.
Process Biochemistry,
29 (3),
181-185.
Artículo
591 - Bravo,A., Quintero,R., Diaz,C., Martinez,A., Soberon,M.. Efficiency of insecticidal crystal protein production in a Bacillus thuringiensis mutant with derepressed expression of the terminal oxidase aa3 during sporulation.
Applied Microbiology and Biotechnology,
39 (4-5),
558-562.
Artículo
592 - Bravo,A., Hendrikx,K., Jansens,S., Peferoen,M.. Immunocytochemical analysis of specific binding of Bacillus thuringiensis insecticidal crystal proteins to lepidopteran and coleopteran mudgut membranes.
Journal of Invertebrate Pathology,
60 (3),
247-253.
Artículo
593 - Bravo,A., Jansens,S., Peferoen,M.. Immunocytochemical localization of Bacillus thuringiensis insecticidal crystal proteins in intoxicated insects.
Journal of Invertebrate Pathology,
60 (3),
237-246.
Artículo
594 - Pereyra-Alferez,B., Bravo,A., Quintero,R., Soberon,X.. The delta-endotoxin protein family displays a hydrophobic motif that might be implicated in toxicity.
Molecular Microbiology,
6 (15),
2095-2098.
595 - Bravo de la Parra, Ma Alejandra. Relacion entre la asimilacion de amonio y la fijacion de nitrogeno en Rhizobium phaseoli.
CIFN,
Doctoradoen Investigacion Biomedica Basica,
UNAM.
*
Asesor: Mora, Jaime
Artículo
596 - Folch,J.L., Antaramian,A., Rodriguez,L., Bravo,A., Brunner,A., Gonzalez,A.. Isolation and characterization of a Saccharomyces cerevisiae mutant with impaired glutamate synthase activity.
Journal of Bacteriology,
171 (12),
6776-6781.
*
Artículo
597 - Bravo,A., Mora,J.. Ammonium assimilation in Rhizobium phaseoli by the glutamine synthetase-glutamate synthase pathway.
Journal of Bacteriology,
170 (2),
980-984.
*
Note
598 - Bravo,A., Becerril,B., Mora,J.. Introduction of the Escherichia coli gdhA gene into Rhizobium phaseoli: effect on nitrogen fixation.
Journal of Bacteriology,
170 (2),
985-988.
*