Biól. Filiberto Sanchez Lopez
Técnico Académico Titular B Tiempo Completo
Estudios genómicos, bioquímicos de la interacción de la microbiota con distintos hospederos
Nivel B del PRIDE
* Indica publicación con otra institución de adscripción
Total de publicaciones: 25
- Tipo
- Fecha
Artículo
1 - Gallardo-Becerra,L., Cornejo-Granados,F., Bikel,S., Arenas,I., Lopez-Leal,G., Alvarado-Gonzalez,C., Sanchez-Lopez,F., Manzo,R., Corzo,G., Espino-Solis,G.P., Canizales-Quinteros,S., Ochoa-Leyva,A. (2026). Bioactive Plasmid- and Phage-Encoded Antimicrobial Peptides (AMPs) in the Human Gut: A Metatranscriptome-Virome Profiling Reveals Exploratory Links to Metabolic Human Diseases.
Microbial Ecology,
89,
15.
Artículo
2 - Cervantes-Echeverria,M., Jimenez-Rico,M.A., Manzo,R., Hernandez-Reyna,A., Cornejo-Granados,F., Bikel,S., Gonzalez,V., Hurtado-Ramirez,J.M., Sanchez-Lopez,F., Salazar-Leon,J., Pedraza-Alva,G., Perez-Martinez,L., Ochoa-Leyva,A. (2025). Human-derived fecal virome transplantation (FVT) reshapes the murine gut microbiota and virome, enhancing glucose regulation.
PLoS ONE,
20 (12),
e0337760.
Artículo
3 - Jatuyosporn,T., Laohawutthichai,P., Ochoa-Romo,J.P., Gallardo-Becerra,L., Sanchez-Lopez,F., Tassanakajon,A., Ochoa-Leyva,A., Krusong,K. (2023). White spot syndrome virus impact on the expression of immune genes and gut microbiome of black tiger shrimp Penaeus monodon.
Scientific Reports,
13 (1),
996.
Artículo
4 - Ochoa-Romo,J.P., Cornejo-Granados,F., Lopez-Zavala,A.A., Viana,M.T., Sanchez,F., Gallardo-Becerra,L., Luque-Villegas,M., Valdez-Lopez,Y., Sotelo-Mundo,R.R., Cota-Huizar,A., Lopez-Munguia,A., Ochoa-Leyva,A. (2022). Agavin induces beneficial microbes in the shrimp microbiota under farming conditions.
Scientific Reports,
12 (1),
6392.
Artículo
5 - Bikel,S., Lopez-Leal,G., Cornejo-Granados,F., Gallardo-Becerra,L., Garcia-Lopez,R., Sanchez,F., Equihua-Medina,E., Ochoa-Romo,J.P., Lopez-Contreras,B.E., Canizales-Quinteros,S., Hernandez-Reyna,A., Mendoza-Vargas,A., Ochoa-Leyva,A. (2021). Gut dsDNA virome shows diversity and richness alterations associated with childhood obesity and metabolic syndrome.
iScience,
24 (8),
102900.
Artículo
6 - Gomez-Fuentes,S., Hernandez-de la Fuente,S., Morales-Ruiz,V., Lopez-Recinos,D., Guevara-Salinas,A., Parada-Colin,M.C., Espitia,C., Ochoa-Leyva,A., Sanchez,F., Villalobos,N., Arce-Sillas,A., Hernandez,M., Mora,S.I., Fragoso,G., Sciutto,E., Adalid-Peralta,L. (2021). A novel, sequencing-free strategy for the functional characterization of Taenia solium proteomic fingerprint.
PLoS Neglected Tropical Diseases,
15 (2),
e0009104.
Artículo
7 - Valenzuela-Chavira,I., Corona-Martinez,D.O., Garcia-Orozco,K.D., Beltran-Torres,M., Sanchez-Lopez,F., Arvizu-Flores,A.A., Sugich-Miranda,R., Lopez-Zavala,A.A., Robles-Zepeda,R.E., Islas-Osuna,M.A., Ochoa-Leyva,A., Toney,M.D., Serrano-Posada,H., Sotelo-Mundo,R.R. (2021). A Novel Glutathione S-Transferase Gtt2 Class (VpGSTT2) Is Found in the Genome of the AHPND/EMS Vibrio parahaemolyticus Shrimp Pathogen.
Toxins,
13 (9),
664.
Artículo
8 - Garcia-Lopez,R., Cornejo-Granados,F., Lopez-Zavala,A.A., Sanchez-Lopez,F., Cota-Huizar,A., Sotelo-Mundo,R.R., Guerrero,A., Mendoza-Vargas,A., Gomez-Gil,B., Ochoa-Leyva,A. (2020). Doing More with Less: A Comparison of 16S Hypervariable Regions in Search of Defining the Shrimp Microbiota.
Microorganisms,
8 (1).
Artículo
9 - Cervantes-Echeverria,M., Equihua-Medina,E., Cornejo-Granados,F., Hernandez-Reyna,A., Sanchez,F., Lopez-Contreras,B.E., Canizales-Quinteros,S., Ochoa-Leyva,A. (2018). Whole-genome of Mexican-crAssphage isolated from the human gut microbiome.
BMC Research Notes,
11 (1),
902.
Artículo
10 - Gonzalez-Felix, M.L., Gatlin, D.M., Urquidez-Bejarano, P., de la Ree-Rodriguez, C., Duarte-Rodriguez, L., Sanchez, F., Casas-Reyes, A., Yamamoto, F.Y., Ochoa-Leyva, A., Perez-Velazquez, M. (2018). Effects of commercial dietary prebiotic and probiotic supplements on growth, innate immune responses, and intestinal microbiota and histology of Totoaba macdonaldi.
Aquaculture,
491,
239-251.
Artículo
11 - Bikel, S., Jacobo-Albavera, L., Sanchez-Munoz, F., Cornejo-Granados, F., Canizales-Quinteros, S., Soberon, X., Sotelo-Mundo, R.R., Del Rio-Navarro, B.E., Mendoza-Vargas, A., Sanchez, F., Ochoa-Leyva, A. (2017). A novel approach for human whole transcriptome analysis based on absolute gene expression of microarray data.
PeerJ,
5,
e4133.
Artículo
12 - Bobes, R.J., Navarrete-Perea, J., Ochoa-Leyva, A., Anaya, V.H., Hernandez, M., Cervantes-Torres, J., Estrada, K., Sanchez-Lopez, F., Soberon, X., Rosas, G., Maroni-Nunes C., Garcia-Varela, M., Sotelo-Mundo, R.R., Lopez-Zavala, A.A., Gevorkian, G., Acero, G., Laclette, J.P., Fragoso, G., Sciutto, E. (2017). Experimental and theoretical approaches to investigate the immunogenicity of Taenia solium-derived KE7 antigen.
Infection and Immunity,
85,
e00395-17.
Artículo
13 - Cornejo-Granados, F., Zatarain-Barron, Z.L., Cantu-Robles, V.A., Mendoza-Vargas, A., Molina-Romero, C., Sanchez, F., Del Pozo-Yauner, L., Hernandez-Pando, R., Ochoa-Leyva, A. (2017). Secretome Prediction of Two M. tuberculosis Clinical Isolates Reveals Their High Antigenic Density and Potential Drug Targets.
Frontiers in Microbiology,
8,
128.
Artículo
14 - Cornejo-Granados, F., Lopez-Zavala, A.A., Gallardo-Becerra, L., Mendoza-Vargas, A., Sanchez, F., Vichido, R., Brieba, L.G., Viana, M.T., Sotelo-Mundo, R.R., Ochoa-Leyva, A. (2017). Microbiome of Pacific Whiteleg shrimp reveals differential bacterial community composition between Wild, Aquacultured and AHPND/EMS outbreak conditions.
Scientific Reports,
7 (1),
11783.
Artículo
15 - Lopez-de Los Santos Y., Chan,H., Cantu,V.A., Rettner,R., Sanchez,F., Zhang,Z., Saier,M.H., Soberon,X. (2012). Genetic engineering of the phosphocarrier protein NPr of the Escherichia coli phosphotransferase system selectively improves sugar uptake activity.
Journal of Biological Chemistry,
287 (35),
29931-29939.
Artículo
16 - Ochoa-Leyva,A., Barona-Gomez,F., Saab-Rincon,G., Verdel-Aranda,K., Sanchez,F., Soberon,X. (2011). Exploring the Structure-Function Loop Adaptability of a (beta/alpha)(8)-Barrel Enzyme through Loop Swapping and Hinge Variability.
Journal of Molecular Biology,
411 (1),
143-157.
Artículo
17 - Ochoa-Leyva,A., Soberon,X., Sanchez,F., Arguello,M., Montero-Moran,G., Saab-Rincon,G. (2009). Protein design through systematic catalytic loop exchange (SCLE) in the (beta/alpha)(8)-fold.
Journal of Molecular Biology,
387 (4),
949-964.
Artículo
18 - Saab-Rincon,G., Mancera,E., Montero-Moran,G., Sanchez,F., Soberon,X. (2005). Generation of variability by in vivo recombination of halves of a (beta/alpha)(8) barrel protein.
Biomolecular Engineering,
22 (4),
113-120.
Artículo
19 - Gaytan,P., Yanez,J., Sanchez,F., Soberon,X. (2001). Orthogonal combinatorial mutagenesis: a codon-level combinatorial mutagenesis method useful for low multiplicity and amino acid-scanning protocols.
Nucleic Acids Research,
29 (3),
E9.
Artículo
20 - Saab-Rincon,G., Juarez,V.R., Osuna,J., Sanchez,F., Soberon,X. (2001). Different strategies to recover the activity of monomeric triosephosphate isomerase by directed evolution.
Protein Engineering,
14 (3),
149-155.
Artículo
21 - Gaytan,P., Yanez,J., Sanchez,F., Mackie,H., Soberon,X. (1998). Combination of DMT-mononucleotide and Fmoc-trinucleotide phosphoramidites in oligonucleotide synthesis affords an automatable codon-level mutagenesis method.
Chemistry and Biology,
5 (9),
519-527.
Artículo
Preprint
23 - Cervantes-Echeverria,M.J., Jimenez-Rico,M.A., Manzo,R., Hernandez-Reyna,A., Cornejo-Granados,F., Sanchez-Lopez,F., Salazar-Leon,J., Pedraza-Alva,G., Perez-Martinez,L., Ochoa-Leyva,A. (2024). Fecal Virome Transplantation (FVT) from healthy humans remodels the gut bacteriome and virome and reduces metabolic syndrome in mice.
bioRxiv,
Preprint posted February 18.
Protocolo
Preprint
25 - Bikel,S., Lopez-Leal,G., Cornejo-Granados,F., Gallardo-Becerra,L., Sanchez,F., Equihua-Medina,E., Ochoa-Romo,J.P., Lopez-Contreras,B.E., Canizales-Quinteros,S., Ochoa-Leyva,A. (2020). Gut Phageome Analysis Reveals Disease-Specific Hallmarks in Childhood Obesity.
bioRxiv,
Preprint posted July 30.
Artículo
26 - Gallardo-Becerra,L., Cornejo-Granados,F., Bikel,S., Arenas,I., Lopez-Leal,G., Alvarado-Gonzalez,C., Sanchez-Lopez,F., Manzo,R., Corzo,G., Espino-Solis,G.P., Canizales-Quinteros,S., Ochoa-Leyva,A.. Bioactive Plasmid- and Phage-Encoded Antimicrobial Peptides (AMPs) in the Human Gut: A Metatranscriptome-Virome Profiling Reveals Exploratory Links to Metabolic Human Diseases.
Microbial Ecology,
89,
15.
Artículo
27 - Cervantes-Echeverria,M., Jimenez-Rico,M.A., Manzo,R., Hernandez-Reyna,A., Cornejo-Granados,F., Bikel,S., Gonzalez,V., Hurtado-Ramirez,J.M., Sanchez-Lopez,F., Salazar-Leon,J., Pedraza-Alva,G., Perez-Martinez,L., Ochoa-Leyva,A.. Human-derived fecal virome transplantation (FVT) reshapes the murine gut microbiota and virome, enhancing glucose regulation.
PLoS ONE,
20 (12),
e0337760.
Preprint
28 - Cervantes-Echeverria,M.J., Jimenez-Rico,M.A., Manzo,R., Hernandez-Reyna,A., Cornejo-Granados,F., Sanchez-Lopez,F., Salazar-Leon,J., Pedraza-Alva,G., Perez-Martinez,L., Ochoa-Leyva,A.. Fecal Virome Transplantation (FVT) from healthy humans remodels the gut bacteriome and virome and reduces metabolic syndrome in mice.
bioRxiv,
Preprint posted February 18.
Artículo
29 - Jatuyosporn,T., Laohawutthichai,P., Ochoa-Romo,J.P., Gallardo-Becerra,L., Sanchez-Lopez,F., Tassanakajon,A., Ochoa-Leyva,A., Krusong,K.. White spot syndrome virus impact on the expression of immune genes and gut microbiome of black tiger shrimp Penaeus monodon.
Scientific Reports,
13 (1),
996.
Protocolo
Artículo
31 - Ochoa-Romo,J.P., Cornejo-Granados,F., Lopez-Zavala,A.A., Viana,M.T., Sanchez,F., Gallardo-Becerra,L., Luque-Villegas,M., Valdez-Lopez,Y., Sotelo-Mundo,R.R., Cota-Huizar,A., Lopez-Munguia,A., Ochoa-Leyva,A.. Agavin induces beneficial microbes in the shrimp microbiota under farming conditions.
Scientific Reports,
12 (1),
6392.
Artículo
32 - Bikel,S., Lopez-Leal,G., Cornejo-Granados,F., Gallardo-Becerra,L., Garcia-Lopez,R., Sanchez,F., Equihua-Medina,E., Ochoa-Romo,J.P., Lopez-Contreras,B.E., Canizales-Quinteros,S., Hernandez-Reyna,A., Mendoza-Vargas,A., Ochoa-Leyva,A.. Gut dsDNA virome shows diversity and richness alterations associated with childhood obesity and metabolic syndrome.
iScience,
24 (8),
102900.
Artículo
33 - Gomez-Fuentes,S., Hernandez-de la Fuente,S., Morales-Ruiz,V., Lopez-Recinos,D., Guevara-Salinas,A., Parada-Colin,M.C., Espitia,C., Ochoa-Leyva,A., Sanchez,F., Villalobos,N., Arce-Sillas,A., Hernandez,M., Mora,S.I., Fragoso,G., Sciutto,E., Adalid-Peralta,L.. A novel, sequencing-free strategy for the functional characterization of Taenia solium proteomic fingerprint.
PLoS Neglected Tropical Diseases,
15 (2),
e0009104.
Artículo
34 - Valenzuela-Chavira,I., Corona-Martinez,D.O., Garcia-Orozco,K.D., Beltran-Torres,M., Sanchez-Lopez,F., Arvizu-Flores,A.A., Sugich-Miranda,R., Lopez-Zavala,A.A., Robles-Zepeda,R.E., Islas-Osuna,M.A., Ochoa-Leyva,A., Toney,M.D., Serrano-Posada,H., Sotelo-Mundo,R.R.. A Novel Glutathione S-Transferase Gtt2 Class (VpGSTT2) Is Found in the Genome of the AHPND/EMS Vibrio parahaemolyticus Shrimp Pathogen.
Toxins,
13 (9),
664.
Artículo
35 - Garcia-Lopez,R., Cornejo-Granados,F., Lopez-Zavala,A.A., Sanchez-Lopez,F., Cota-Huizar,A., Sotelo-Mundo,R.R., Guerrero,A., Mendoza-Vargas,A., Gomez-Gil,B., Ochoa-Leyva,A.. Doing More with Less: A Comparison of 16S Hypervariable Regions in Search of Defining the Shrimp Microbiota.
Microorganisms,
8 (1).
Preprint
36 - Bikel,S., Lopez-Leal,G., Cornejo-Granados,F., Gallardo-Becerra,L., Sanchez,F., Equihua-Medina,E., Ochoa-Romo,J.P., Lopez-Contreras,B.E., Canizales-Quinteros,S., Ochoa-Leyva,A.. Gut Phageome Analysis Reveals Disease-Specific Hallmarks in Childhood Obesity.
bioRxiv,
Preprint posted July 30.
Artículo
37 - Cervantes-Echeverria,M., Equihua-Medina,E., Cornejo-Granados,F., Hernandez-Reyna,A., Sanchez,F., Lopez-Contreras,B.E., Canizales-Quinteros,S., Ochoa-Leyva,A.. Whole-genome of Mexican-crAssphage isolated from the human gut microbiome.
BMC Research Notes,
11 (1),
902.
Artículo
38 - Gonzalez-Felix, M.L., Gatlin, D.M., Urquidez-Bejarano, P., de la Ree-Rodriguez, C., Duarte-Rodriguez, L., Sanchez, F., Casas-Reyes, A., Yamamoto, F.Y., Ochoa-Leyva, A., Perez-Velazquez, M.. Effects of commercial dietary prebiotic and probiotic supplements on growth, innate immune responses, and intestinal microbiota and histology of Totoaba macdonaldi.
Aquaculture,
491,
239-251.
Artículo
39 - Bikel, S., Jacobo-Albavera, L., Sanchez-Munoz, F., Cornejo-Granados, F., Canizales-Quinteros, S., Soberon, X., Sotelo-Mundo, R.R., Del Rio-Navarro, B.E., Mendoza-Vargas, A., Sanchez, F., Ochoa-Leyva, A.. A novel approach for human whole transcriptome analysis based on absolute gene expression of microarray data.
PeerJ,
5,
e4133.
Artículo
40 - Bobes, R.J., Navarrete-Perea, J., Ochoa-Leyva, A., Anaya, V.H., Hernandez, M., Cervantes-Torres, J., Estrada, K., Sanchez-Lopez, F., Soberon, X., Rosas, G., Maroni-Nunes C., Garcia-Varela, M., Sotelo-Mundo, R.R., Lopez-Zavala, A.A., Gevorkian, G., Acero, G., Laclette, J.P., Fragoso, G., Sciutto, E.. Experimental and theoretical approaches to investigate the immunogenicity of Taenia solium-derived KE7 antigen.
Infection and Immunity,
85,
e00395-17.
Artículo
41 - Cornejo-Granados, F., Zatarain-Barron, Z.L., Cantu-Robles, V.A., Mendoza-Vargas, A., Molina-Romero, C., Sanchez, F., Del Pozo-Yauner, L., Hernandez-Pando, R., Ochoa-Leyva, A.. Secretome Prediction of Two M. tuberculosis Clinical Isolates Reveals Their High Antigenic Density and Potential Drug Targets.
Frontiers in Microbiology,
8,
128.
Artículo
42 - Cornejo-Granados, F., Lopez-Zavala, A.A., Gallardo-Becerra, L., Mendoza-Vargas, A., Sanchez, F., Vichido, R., Brieba, L.G., Viana, M.T., Sotelo-Mundo, R.R., Ochoa-Leyva, A.. Microbiome of Pacific Whiteleg shrimp reveals differential bacterial community composition between Wild, Aquacultured and AHPND/EMS outbreak conditions.
Scientific Reports,
7 (1),
11783.
Artículo
43 - Lopez-de Los Santos Y., Chan,H., Cantu,V.A., Rettner,R., Sanchez,F., Zhang,Z., Saier,M.H., Soberon,X.. Genetic engineering of the phosphocarrier protein NPr of the Escherichia coli phosphotransferase system selectively improves sugar uptake activity.
Journal of Biological Chemistry,
287 (35),
29931-29939.
Artículo
44 - Ochoa-Leyva,A., Barona-Gomez,F., Saab-Rincon,G., Verdel-Aranda,K., Sanchez,F., Soberon,X.. Exploring the Structure-Function Loop Adaptability of a (beta/alpha)(8)-Barrel Enzyme through Loop Swapping and Hinge Variability.
Journal of Molecular Biology,
411 (1),
143-157.
Artículo
45 - Ochoa-Leyva,A., Soberon,X., Sanchez,F., Arguello,M., Montero-Moran,G., Saab-Rincon,G.. Protein design through systematic catalytic loop exchange (SCLE) in the (beta/alpha)(8)-fold.
Journal of Molecular Biology,
387 (4),
949-964.
Artículo
46 - Saab-Rincon,G., Mancera,E., Montero-Moran,G., Sanchez,F., Soberon,X.. Generation of variability by in vivo recombination of halves of a (beta/alpha)(8) barrel protein.
Biomolecular Engineering,
22 (4),
113-120.
Artículo
47 - Gaytan,P., Yanez,J., Sanchez,F., Soberon,X.. Orthogonal combinatorial mutagenesis: a codon-level combinatorial mutagenesis method useful for low multiplicity and amino acid-scanning protocols.
Nucleic Acids Research,
29 (3),
E9.
Artículo
48 - Saab-Rincon,G., Juarez,V.R., Osuna,J., Sanchez,F., Soberon,X.. Different strategies to recover the activity of monomeric triosephosphate isomerase by directed evolution.
Protein Engineering,
14 (3),
149-155.
Artículo
49 - Gaytan,P., Yanez,J., Sanchez,F., Mackie,H., Soberon,X.. Combination of DMT-mononucleotide and Fmoc-trinucleotide phosphoramidites in oligonucleotide synthesis affords an automatable codon-level mutagenesis method.
Chemistry and Biology,
5 (9),
519-527.
Artículo