Dr. Sergio Paulo Alpuche Lazcano
Investigador Asociado C Tiempo Completo
ARN no codificantes del huésped en infecciones por RSV
ARN no codificantes del huésped en infecciones por RSV y alfavirus
ARN terapéutico y vectores de administración
Nivel I del SNII
Doctorado, Doctor
- Activos
-
Licenciatura
-
Estancia Temporal
* Indica publicación con otra institución de adscripción
Total de publicaciones: 13
- Tipo
- Fecha
Artículo
1 - Stuible,M., Alpuche-Lazcano,S.P., Gervais,C., Ouimet,M., Lippens,J., Page,M., Morasse,A., Moraitis,A.N., Durocher,Y. (2025). Endogenous Retrovirus-Like Particle-Deficient CHO Cells Can be Generated by CRISPR or shRNA and Enriched Based on Cell-Surface Expression of Retroviral Envelope Protein.
Biotechnology and Bioengineering,
122 (11),
3192-3204.
*
Revisión
2 - Alpuche-Lazcano,S.P., Scarborough,R.J., Gatignol,A. (2024). MicroRNAs and long non-coding RNAs during transcriptional regulation and latency of HIV and HTLV.
Retrovirology,
21 (1),
5.
*
Revisión
3 - Sanchez-Martinez,Z.V., Alpuche-Lazcano,S.P., Stuible,M., Durocher,Y. (2024). CHO cells for virus-like particle and subunit vaccine manufacturing.
Vaccine,
42 (10),
2530-2542.
*
Artículo
4 - Sanchez-Martinez,Z.V., Alpuche-Lazcano,S.P., Stuible,M., Akache,B., Renner,T.M., Deschatelets,L., Dudani,R., Harrison,B.A., McCluskie,M.J., Hrapovic,S., Blouin,J., Wang,X.Y., Schuller,M., Cui,K., Cho,J.Y., Durocher,Y. (2024). SARS-CoV-2 spike-based virus-like particles incorporate influenza H1/N1 antigens and induce dual immunity in mice.
Vaccine,
42 (26),
126463.
*
Artículo
5 - Alpuche-Lazcano,S.P., Stuible,M., Akache,B., Tran,A., Kelly,J., Hrapovic,S., Robotham,A., Haqqani,A., Star,A., Renner,T.M., Blouin,J., Maltais,J.S., Cass,B., Cui,K., Cho,J.Y., Wang,X., Zoubchenok,D., Dudani,R., Duque,D., McCluskie,M.J., Durocher,Y. (2023). Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells.
Communications medicine,
3 (1),
116.
*
Artículo
6 - Alpuche-Lazcano,S.P., Saliba,J., Costa,V.V., Campolina-Silva,G.H., Marim,F.M., Ribeiro,L.S., Blank,V., Mouland,A.J., Teixeira,M.M., Gatignol,A. (2021). Profound downregulation of neural transcription factor Npas4 and Nr4a family in fetal mice neurons infected with Zika virus.
PLoS Neglected Tropical Diseases,
15 (5).
*
Artículo
7 - Goguen,R.P., Del Corpo,O., Malard,C.M.G., Daher,A., Alpuche-Lazcano,S.P., Chen,M.J., Scarborough,R.J., Gatignol,A. (2021). Efficacy, accumulation, and transcriptional profile of anti-HIV shRNAs expressed from human U6, 7SK, and H1 promoters.
Molecular Therapy Nucleic Acids,
23,
1020-1034.
*
Artículo
8 - Alpuche-Lazcano,S.P., McCullogh,C.R., Del Corpo,O., Rance,E., Scarborough,R.J., Mouland,A.J., Sagan,S.M., Teixeira,M.M., Gatignol,A. (2018). Higher cytopathic effects of a zika virus brazilian isolate from bahia compared to a Canadian-imported thai strain.
Viruses,
10 (2),
53.
*
Artículo nacional
9 - Cerezo-Lira,G., Zarate-Conde,K., Alpuche-Lazcano,S., Cabello,C., Tato,P., Tirado,R. (2016). Diagnóstico molecular para la detección de metapneumovirus humano a partir de aislados virales en pacientes pedi tricos con infección respiratoria aguda [Molecular diagnosis for the detection of human metapneumovirus from viral isolates in pediatric patients with acute respiratory infection].
Investigación en Discapacidad,
5 (2),
88-95.
*
Internacional
10 - Alpuche-Lazcano,S.P., Gatignol,A. (2021). Cytopathicity and pathogenesis of Zika virus strains. Zika Virus Biology, Transmission, and Pathways: Volume 1: The Neuroscience of Zika Virus.
397-407.
*
Preprint
11 - Alpuche-Lazcano,S.P., Dunkey,O.R.S., Scarborough,R.J., Daniels,S.M., Daher,A., Truchi,M., Estable,M.C., Mari,B., Mouland,A.J., Gatignol,A. (2023). The sequestration of miR-642a-3p by a complex formed by HIV-1 Gag and human Dicer increases AFF4 expression and viral production.
bioRxiv,
Preprint posted May 26.
*
12 - Alpuche Lazcano, Sergio Paulo (2020). RNA interference, understanding the collateral effects of HIV-1 and ZIKV.
Department of Medicine,
PhD,
McGill University.
*
Asesor: Gatinol,Anne, Mouland, Andrew J.
13 - Alpuche Lazcano, Sergio Paulo (2012). Detección y genotipificación de virus sincitíal respiratorio humano (HRSV) en muestras de pacientes pediátricos con infección respiratoria aguda.
Facultad de Medicina,
Maestria en Ciencias Biologicas,
UNAM.
*
Asesor: Tirado Mendoza, Rocio
Artículo
14 - Stuible,M., Alpuche-Lazcano,S.P., Gervais,C., Ouimet,M., Lippens,J., Page,M., Morasse,A., Moraitis,A.N., Durocher,Y.. Endogenous Retrovirus-Like Particle-Deficient CHO Cells Can be Generated by CRISPR or shRNA and Enriched Based on Cell-Surface Expression of Retroviral Envelope Protein.
Biotechnology and Bioengineering,
122 (11),
3192-3204.
*
Revisión
15 - Alpuche-Lazcano,S.P., Scarborough,R.J., Gatignol,A.. MicroRNAs and long non-coding RNAs during transcriptional regulation and latency of HIV and HTLV.
Retrovirology,
21 (1),
5.
*
Revisión
16 - Sanchez-Martinez,Z.V., Alpuche-Lazcano,S.P., Stuible,M., Durocher,Y.. CHO cells for virus-like particle and subunit vaccine manufacturing.
Vaccine,
42 (10),
2530-2542.
*
Artículo
17 - Sanchez-Martinez,Z.V., Alpuche-Lazcano,S.P., Stuible,M., Akache,B., Renner,T.M., Deschatelets,L., Dudani,R., Harrison,B.A., McCluskie,M.J., Hrapovic,S., Blouin,J., Wang,X.Y., Schuller,M., Cui,K., Cho,J.Y., Durocher,Y.. SARS-CoV-2 spike-based virus-like particles incorporate influenza H1/N1 antigens and induce dual immunity in mice.
Vaccine,
42 (26),
126463.
*
Artículo
18 - Alpuche-Lazcano,S.P., Stuible,M., Akache,B., Tran,A., Kelly,J., Hrapovic,S., Robotham,A., Haqqani,A., Star,A., Renner,T.M., Blouin,J., Maltais,J.S., Cass,B., Cui,K., Cho,J.Y., Wang,X., Zoubchenok,D., Dudani,R., Duque,D., McCluskie,M.J., Durocher,Y.. Preclinical evaluation of manufacturable SARS-CoV-2 spike virus-like particles produced in Chinese Hamster Ovary cells.
Communications medicine,
3 (1),
116.
*
Preprint
19 - Alpuche-Lazcano,S.P., Dunkey,O.R.S., Scarborough,R.J., Daniels,S.M., Daher,A., Truchi,M., Estable,M.C., Mari,B., Mouland,A.J., Gatignol,A.. The sequestration of miR-642a-3p by a complex formed by HIV-1 Gag and human Dicer increases AFF4 expression and viral production.
bioRxiv,
Preprint posted May 26.
*
Artículo
20 - Alpuche-Lazcano,S.P., Saliba,J., Costa,V.V., Campolina-Silva,G.H., Marim,F.M., Ribeiro,L.S., Blank,V., Mouland,A.J., Teixeira,M.M., Gatignol,A.. Profound downregulation of neural transcription factor Npas4 and Nr4a family in fetal mice neurons infected with Zika virus.
PLoS Neglected Tropical Diseases,
15 (5).
*
Artículo
21 - Goguen,R.P., Del Corpo,O., Malard,C.M.G., Daher,A., Alpuche-Lazcano,S.P., Chen,M.J., Scarborough,R.J., Gatignol,A.. Efficacy, accumulation, and transcriptional profile of anti-HIV shRNAs expressed from human U6, 7SK, and H1 promoters.
Molecular Therapy Nucleic Acids,
23,
1020-1034.
*
Internacional
22 - Alpuche-Lazcano,S.P., Gatignol,A.. Cytopathicity and pathogenesis of Zika virus strains. Zika Virus Biology, Transmission, and Pathways: Volume 1: The Neuroscience of Zika Virus.
397-407.
*
23 - Alpuche Lazcano, Sergio Paulo. RNA interference, understanding the collateral effects of HIV-1 and ZIKV.
Department of Medicine,
PhD,
McGill University.
*
Asesor: Tirado Mendoza, Rocio
Artículo
24 - Alpuche-Lazcano,S.P., McCullogh,C.R., Del Corpo,O., Rance,E., Scarborough,R.J., Mouland,A.J., Sagan,S.M., Teixeira,M.M., Gatignol,A.. Higher cytopathic effects of a zika virus brazilian isolate from bahia compared to a Canadian-imported thai strain.
Viruses,
10 (2),
53.
*
Artículo nacional
25 - Cerezo-Lira,G., Zarate-Conde,K., Alpuche-Lazcano,S., Cabello,C., Tato,P., Tirado,R.. Diagnóstico molecular para la detección de metapneumovirus humano a partir de aislados virales en pacientes pedi tricos con infección respiratoria aguda [Molecular diagnosis for the detection of human metapneumovirus from viral isolates in pediatric patients with acute respiratory infection].
Investigación en Discapacidad,
5 (2),
88-95.
*
26 - Alpuche Lazcano, Sergio Paulo. Detección y genotipificación de virus sincitíal respiratorio humano (HRSV) en muestras de pacientes pediátricos con infección respiratoria aguda.
Facultad de Medicina,
Maestria en Ciencias Biologicas,
UNAM.
*
Asesor: Tirado Mendoza, Rocio