. Instituto de Biotecnologia UNAM

IBT-UNAM : Dr. Leobardo Serrano Carreón

Dr. Leobardo Serrano Carreón

Encargado de la Unidad de Escalamiento y Planta Piloto
Coordinador de Otros Posgrados (UNAM-UAEM)
Investigador
Tutor de Maestría y Doctorado
Nivel II del SNI
Grupo del Dr. Enrique Galindo

email: leobardo @ibt.unam.mx
Teléfonos
Oficina +52 (777) 329-1630
desde la CDMX 562-27630
red UNAM 27630

- Licenciatura: Ingeniero Bioquímico Industrial, Universidad Autonoma Metropolitana-Iztapalapa (1986)
- Maestría: en Ciencias, Universidad de Bourgona, ENS.BANA, Dijon, Francia (1989)
- Doctorado: en Biotecnología, Universidad de Bourgona, (ENS.BANA), Dijon, Francia (1992)
- Mencion honorífica en examen de Maestría (1989)
- Mencion honorífica en examen de Doctorado (1992)

Premio Mentes Quo+Discovery en la Categoría Mentes Humana al Programa Adopte un Talento (PAUTA) Discovery Channel Mexico (2012)
Mención Honorífica en el área de Investigación Tecnológica en el Premio CANIFARMA CANIFARMA (2007)
Distinción Universidad Nacional para Jóvenes Académicos en el área de Innovación Tecnológica y Diseño Industrial (2003)
Premio Nacional en Ciencia y Tecnología de Alimentos (2002)
Premio Nacional de Ciencia y Tecnología de Alimentos, categoría profesional CONACyT e Industria Mexicana Coca-Cola (2002)
Premio de la Sociedad Mexicana de Instrumentación A.C. XIII Congreso de Instrumentación, Ensenada Baja California (1998)

Estudiantes

M.C Karina Alejandra Balderas

Ing. Hector Manuel Tablas

Luis Alonso Gimeno

Ing. Cristina De los Santos

M.C. Esmeralda Yazmin Soriano

Daniela Barrón

Publicaciones recientes

Luna-Bulbarela,A. Tinoco-Valencia,R. Corzo,G. Kazuma,K. Konno,K. Galindo,E. Serrano-Carreon,L. 2018. Effects of bacillomycin D homologues produced by Bacillus amyloliquefaciens 83 on growth and viability of Colletotrichum gloeosporioides at different physiological stages Biological Control, 127, 145-154.

Rosas-Galvan,N.S. Martinez-Morales,F. Marquina-Bahena,S. Tinoco-Valencia,R. Serrano-Carreon,L. Bertrand,B. Leon-Rodriguez,R. Guzman-Aparicio,J. Alvarez-Berber,L. Trejo-Hernandez,M.D.R. 2018. Improved production, purification and characterization of biosurfactants produced by Serratia marcescens SM3 and its isogenic SMRG-5 strain Biotechnology and Applied Biochemistry, 85, 690-700.

Bertrand,B. Mayolo-Deloisa,K. Gonzalez-Gonzalez,M. Tinoco-Valencia,R. Serrano-Carreon,L. Martinez-Morales,F. Trejo-Hernandez,M.R. Rito-Palomares,M. 2016. Pleurotus ostreatus laccase recovery from residual compost using aqueous two-phase systems Journal of Chemical Technology and Biotechnology, 91, 2235-2242.

Fernandez-Alejandre,K.I. Flores,N. Tinoco-Valencia,R. Caro,M. Flores,C. Galindo,E. Serrano-Carreon,L. 2016. Diffusional and transcriptional mechanisms involved in laccases production by Pleurotus ostreatus CP50 Journal of Biotechnology, 223, 42-49.

Dantan-Gonzalez,E. Quiroz-Castaneda,R.E. Cobaxin-Cardenas,M. Valle-Hernandez,J. Gama-Martinez,Y. Tinoco-Valencia,J.R. Serrano-Carreon,L. Ortiz-Hernandez,L. 2015. Impact of Meyerozyma guilliermondii isolated from chickens against Eimeria sp. protozoan, an in vitro analysis BMC Veterinary Research, 11, 278.

Tinoco-Valencia,R. Gomez-Cruz,C. Galindo,E. Serrano-Carreon,L. 2014. Toward an understanding of the effects of agitation and aeration on growth and laccases production by Pleurotus ostreatus Journal of Biotechnology, 177, 67-73.

Bertrand,B. Martinez-Morales,F. Tinoco,R. Rojas-Trejo,S. Serrano-Carreon,L. Trejo-Hernandez,M.R. 2014. Induction of laccases in Trametes versicolor by aqueous wood extracts World Journal Of Microbiology & Biotechnology, 30, 135-142.

Garibay-Hernandez,A. Vazquez-Duhalt,R. Serrano-Carreon,L. Martinez,A. 2013. Nitrogen Limitation in Neochloris oleoabundans: A Reassessment of Its Effect on Cell Growth and Biochemical Composition Applied Biochemistry and Biotechnology, 171, 1775-1791.

Galindo,E. Serrano-Carreon,L. Gutierrez,C.R. Allende,R. Balderas,K. Patino,M. Trejo,M. Wong,M.A. Rayo,E. Isauro,D. Jurado,C. 2013. The challenges of introducing a new biofungicide to the market: A case study Electronic Journal of Biotechnology, 16, .

Munoz-Celaya,A.L. Ortiz-Garcia,M. Vernon-Carter,E.J. Jauregui-Rincon,J. Galindo,E. Serrano-Carreon,L. 2012. Spray-drying microencapsulation of Trichoderma harzianum conidias in carbohydrate polymers matrices Carbohydrate Polymers, 88, 1141-1148.

Fernandez-Sandoval,M.T. Ortiz-Garcia,M. Galindo,E. Serrano-Carreon,L. 2012. Cellular damage during drying and storage of Trichoderma harzianum spores Process Biochemistry, 47, 186-194.

Tinoco,R. Acevedo,A. Galindo,E. Serrano-Carreon,L. 2011. Increasing Pleurotus ostreatus laccase production by culture medium optimization and copper/lignin synergistic induction Journal of Industrial Microbiology & Biotechnology, 38, 531-540.

Flores,C. Casasanero,R. Trejo-Hernandez,M.R. Galindo,E. Serrano-Carreon,L. 2010. Production of laccases by Pleurotus ostreatus in submerged fermentation in co-culture with Trichoderma viride Journal of Applied Microbiology, 108, 810-817.

Flores,C. Vidal,C. Trejo-Hernandez,M.R. Galindo,E. Serrano-Carreon,L. 2009. Selection of Trichoderma strains capable of increasing laccase production by Pleurotus ostreatus and Agaricus bisporus in dual cultures Journal of Applied Microbiology, 106, 249-257.

Corkidi,G. Serrano-Carreon,L. Galindo,E. 2008. Análisis digital de imágenes para la caracterización microscópica de parámetros críticos en la producción fermentativa de metabolitos secundarios Revista Colombiana de Biotecnología, 10, 75-93.

Rocha-Valadez,J.A. Galindo,E. Serrano-Carreon,L. 2007. The influence of circulation frequency on fungal morphology: A case study considering Kolmogorov microscale in constant specific energy dissipation rate cultures of Trichoderma harzianum Journal of Biotechnology, 130, 394-401.

Rocha-Valadez,J.A. Albiter,V. Caro,M.A. Serrano-Carreon,L. Galindo,E. 2007. A fermentation system designed to independently evaluate mixing and/or oxygen tension effects in microbial processes: development, application and performance Bioprocess and Biosystems Engineering, 30, 115-122.

Rocha-Valadez,J.A. Estrada,M. Galindo,E. Serrano-Carreon,L. 2006. From shake flasks to stirred fermentors: Scale-up of an extractive fermentation process for 6-pentyl-?-pyrone production by Trichoderma harzianum using volumetric power input Process Biochemistry, 41, 1347-1352.

Aguilar,O. Albiter,V. Serrano-Carreon,L. Rito-Palomares,M. 2006. Direct comparison between ion-exchange chromatography and aqueous two-phase processes for the partial purification of penicillin acylase produced by E. coli Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 835, 77-83.

Corkidi,G. Balderas-Ruiz,K.A. Taboada,B. Serrano-Carreon,L. Galindo,E. 2006. Assessing mango anthracnose using a new three-dimensional image-analysis technique to quantify lesions on fruit Plant Pathology, 55, 250-257.

Rocha-Valadez,J.A. Hassan,M. Corkidi,G. Flores,C. Galindo,E. Serrano-Carreon,L. 2005. 6-pentyl-alpha-pyrone production by Trichoderma harzianum: The influence of energy dissipation rate and its implications on fungal physiology Biotechnology and Bioengineering, 91, 54-61.

Serrano-Carreon,L. Flores,C. Rodriguez,B. Galindo,E. 2004. Rhizoctonia solani, an elicitor of 6-pentyl-alpha-pyrone production by Trichoderma harzianum in a two liquid phases, extractive fermentation system Biotechnology Letters, 26, 1403-1406.

Galindo,E. Flores,C. Larralde-Corona,P. Corkidi-Blanco,G. Rocha-Valadez,J.A. Serrano-Carreon,L. 2004. Production of 6-pentyl--pyrone by Trichoderma harzianum cultured in unbaffled and baffled shake flasks, Biochemical Engineering Journal, 18, 1-8.

Hassan,M. Corkidi,G. Galindo,E. Flores,C. Serrano-Carreon,L. 2002. Accurate and rapid viability assessment of Trichoderma harzianum using fluorescence-based digital image analysis Biotechnology and Bioengineering, 80, 677-684.

Serrano-Carreon,L. Balderas-Ruiz,K. Galindo,E. Rito-Palomares,M. 2002. Production and biotransformation of 6-pentyl-alpha-pyrone by Trichoderma harzianum in two-phase culture systems Applied Microbiology and Biotechnology, 58, 170-174.

Cordova-Aguilar,S. Sanchez,A. Serrano-Carreon,L. Galindo,E. 2001. Oil and fungal biomass dispersion in a stirred tank containing a stimulated fermentation broth Journal of Chemical Technology and Biotechnology, 76, 1101-1106.

Rito-Palomares,M. Negrete,A. Miranda,L. Flores,C. Galindo,E. Serrano-Carreon,L. 2001. The potential application of aqueous two-phase systems for in situ recovery of 6-pentyl-alfa-pyrone produced by Trichoderma harzianum Enzyme and Microbial Technology, 28, 625-631.

Rito-Palomares,M. Negrete,A. Galindo,E. Serrano-Carreon,L. 2000. Aroma compounds recovery from mycelial cultures in aqueous two-phase processes Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 743, 403-408.

Rocha-Valadez,J.A. Galindo,E. Serrano-Carreon,L. 2000. Effect of the impeller-sparger configuration over Trichoderma harzianum growth in four-phases cultures under constant dissolved oxygen Bioprocess Engineering, 23, 403-410.

Amanullah,A. Serrano-Carreon,L. Castro,B. Galindo,E. Nienow,A.W. 1998. 3.0.CO;2-7> The influence of impeller type in pilot scale xanthan fermentations Biotechnology and Bioengineering, 57, 95-108.

Serrano-Carreon,L. Corona,R.M. Sanchez,A. Galindo,E. 1998. Prediction of xanthan fermentation development by a model linking kinetics, power drawn and mixing Process Biochemistry, 33, 133-146.

Serrano-Carreon,L. Flores,C. Galindo,E. 1997. gamma-decalactone production by Trichoderma harzianum in stirred bioreactors Biotechnology Progress, 13, 205-208.

Amanullah,A. Serrano,L.C. Galindo,E. Nienow,A.W. 1996. Reproducibility of pilot scale xanthan fermentations Biotechnology Progress, 12, 466-473.

Serrano-Carreon,L. Salcedo,G. Ramirez,M.E. Galindo,E. 1995. Kinetics and broth rheology evolution during xanthan production by Xanthomonas campestris cultured in shake flasks.Asia-Pacific Journal Of Molecular Biology And Biotechnology, 3, 67-73.

Boccas,F. Roussos,S. Gutierrez,M. Serrano,L. Viniegra,G.G. 1994. Production of Pectinase from Coffee Pulp in Solid-State Fermentation System.Journal of Food Science and Technology-Mysore, 31, 22-26 * .

Serrano-Carreon,L. Hathout,Y. Bensoussan,M. Belin,J.M. 1993. Metabolism of linoleic acid or mevalonate and 6-pentyl-a-pyrone biosynthesis by Trichoderma species Applied and Environmental Microbiology, 59, 2945-2950 * .

Belin,J.M. Bensoussan,M. Serrano-Carreon,L. 1992. Microbial biosynthesis for the production of food flavours Trends in Food Science & Technology, 3, 11-14 * .

Serrano-Carreon,L. Hathout,Y. Bensoussan,M. Belin,J.M. 1992. Quantitative separation of Trichoderma lipid classes on a bonded phase column Journal of Chromatography, 584, 129-133 * .

Serrano-Carreon,L. Hathout,Y. Bensoussan,M. Belin,J.M. 1992. Lipid accumulation in Trichoderma species Fems Microbiology Letters, 93, 181-187 * .

Serrano-Carreon,L. Hathout,Y. Bensoussan,M. Belin,J.M. 1992. Production of 6-pentyl-a-pyrone by Trichoderma harzianum from 18:n fatty acid methyl esters Biotechnology Letters, 14, 1019-1024 * .

Libros y capítulos recientes

Serrano-Carreon,L. Galindo,E. Rocha-Valadez,J.A. Holguin-Salas,A. Corkidi,G. 2015. Hydrodynamics, Fungal Physiology, and Morphology en: Bley,T. Filaments in Bioprocesses. pags. 55-90

Galindo,E. Pena,C. Serrano-Carreon,L. 2008. Domesticar microorganismos en un biorreactor: los retos del bioingeniero en: *agustin Una ventana al quehacer científico. Instituto de Biotecnología de la UNAM 25 aniversario, cap 12. Mexico, D.F.. UNAM. pags. 131-143

Serrano-Carreon,L. 2003. Improving biogeneration of aroma compounds by in situ product removal. en: Barbosa-Canovas,G.V. Food Science and Food Biotechnology. CRC Press,. pags. 219-232

Bensoussan,M. Serrano-Carreon,L. 1997. Grape Pulp, Grape Pips and their Mixture: Novel Substrates or Supports for Solid State Fermentation en: Viniegra-Gonzalez,G. Advances in solid state fermentation. Dordrecht. Kluwer Academic. pags. 223-233

GodoySilva,R.D. SerranoCarreon,L. Galindo,E. Ascanio,G. 1997. 25 en: Nienow,A.W. 4Th International Conference on Bioreactor & Bioprocess Fluid Dynamics. pags. 61-72

Divulgación

Fernandez-Alejandre,K.I. Serrano-Carreon,L. 2017. Retos en la producción de lacasas fúngicas en cultivo sumergido: estrés hidrodinámico vs. transferencia de oxígeno. Premio Alfredo Sanchez Marroquin Biotecnologia, 21, 11-27.

Serrano-Carreon,L. 2016. Unidad de Escalamiento y Planta Piloto Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 5, 17-18.

Serrano-Carreon,L. 2016. Bioprocesos con Microorganismos Recombinantes Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 4, 22.

Galindo,E. Serrano-Carreon,L. Gutierrez,C.R. Balderas-Ruiz,K.A. Munoz-Celaya,A.L. Mezo-Villalobos,M. Arroyo-Colin,J. 2015. Desarrollo histórico y los retos tecnológicos y legales para comercializar Fungifree AB®, el primer biofungicida 100% mexicano TIP revista especializada en Ciencias Quimico-Biologicas, 18, 52-60.

Serrano-Carreon,L. Galindo,E. Gutierrez,C.R. 2014. Biopesticide Consolidates Position in the Mexican Market.Biocontrol News and Information, 35, .

Corkidi-Blanco,G. Rojas-Dominguez,A. Balderas-Ruiz,K.A. Sangabriel-Mendoza,J.C. Serrano-Carreon,L. Galindo-Fentanes,E. 2010. Una nueva herramienta para la caracterización precisa y cuantitativa de la Antracnosis del Mango, de utilidad para fitopatólogos, productores y exportadores Claridades Agropecuarias, 198, 39-47.

Serrano-Carreon,L. Balderas-Ruiz,K. kari_abr@hotmail.com Wong-Urrea,M.A. Rosas-Velazquez,D.R. Galindo-Fentanes,E. 2010. Biofungicidas para el control biologico de la antracnosis del mango: logrando frutos de alta calidad internacional para mercados exigentes Claridades Agropecuarias, 208, 28-37.

Garibay-Hernandez,A. Vazquez-Duhalt,R. Sanchez-Saavedra,M.P. Serrano-Carreon,L. Martinez-Jimenez,A. 2009. Biodiesel a Partir de Microalgas Biotecnologia, 13, 38-61.

Serrano-Carreon,L. 2008. Cultivo de Nochebuena: No todos los hongos son enemigos Hypatia, 28, .

Ibarra,J.E. Castro,M.C. Galindo,E. Patino,M. Serrano,L. Garcia,R. Carrillo,J.A. Pereyra-Alferez,B. Alcazar-Pizana,A. Luna-Olvera,H. Galan-Wong,L. Pardo,L. Munoz-Garay,C. Gomez,I. Soberon,M. Bravo,A. 2006. [Microorganisms in the biological control of insects and phytopathogens] Revista Latinoamericana de Microbiologia, 48, 113-120.

Serrano,L. Galindo,E. 2003. Desarrollo tecnológico para el control biológico de fitopatógenos: un reto multidisciplinario Revista Universidad de Mexico, 629, .

Patentes

E. Galindo F., L. Serrano, J. A. Carrillo F., R. Allende M., R. S. García E., L. Trujillo R. y M. Patiño V 2009 Método para obtener una composición sólida de Rhodotorula minuta, efectiva para control biológico de antracnosis y la composición obtenida.UNAM Brasil PI 0621953-5, Ecuador SP 09 9236, Estados Unidos 103557187A y Mexico MX/a/2009/003577. (en trámite)

E. Galindo F., L. Serrano, J. A. Carrillo F., R. Allende M., R. S. García E., L. Trujillo R. y M. Patiño V 2006 Método para obtener una composición sólida de Rhodotorula minuta, efectiva para control biológico de antracnosis y la composición obtenida.UNAM PCT. (en trámite)

* Indica publicación con otra institución de adscripción