Dr. Gerardo Corzo Burguete Departamento de Medicina Molecular y Bioprocesos
Teléfonos Oficina +52 (777) 329-1647desde el D.F. 562-27647 red UNAM 27647 Laboratorio +52 (777) 329-1669 |
- Licenciatura: Ingeniero en Bioquimica Industrial,Universidad Autonoma Metropolitana-Iztapalapa, (1986)
- Maestría: en Biotecnologia, Universidad Nacional Autonoma de Mexico, (1992)
- Doctorado: PhD. en Ciencia de los Alimentos, Oklahoma State University (OSU), Stillwater, OK, USA (1997)
- Estancia de Investigación: National Institute of Advanced Industrial Science & Technology, Tsukuba, Japón (1989-1990).
- Estancia de Investigación: Département d'Ingénierie et d'Etude des Protéines (DIEP), Commissariat a l´Energie Atomique (CEA), Saclay, Gif-sur-Yvette, Francia (2002).
- Estancia Posdoctoral:National Institute of Advanced Industrial Science & Technology, Tsukuba, Japón (1989-1990).
- Research Associate:Suntory Institute for Bioorganic Research, Osaka, Japón (2000-2004).
Lic. Maria Jose Hernández Selma Margarita Jurado M.C. Francia Garcia Bernaldez,J. Roman-Gonzalez,S.A. Martinez,O. Jimenez,S. Vivas,O. Arenas,I. Corzo,G. Arreguin,R. Garcia,D.E. Possani,L.D. Licea,A.
2013. A Conus regularis Conotoxin with a Novel Eight-Cysteine Framework Inhibits CaV2.2 Channels and Displays an Anti-Nociceptive Activity Mar.Drugs, 11, 1188-1202.Publicaciones recientes
Corrales-Garcia,L. Ortiz,E. Castaneda-Delgado,J. Rivas-Santiago,B. Corzo,G.
2013. Bacterial expression and antibiotic activities of recombinant variants of human beta-defensins on pathogenic bacteria and M. tuberculosis Protein Expr.Purif., 89, 33-43.
Caliskan,F. Quintero-Hernandez,V. Restano-Cassulini,R. Coronas-Valderrama,F.I. Corzo,G. Possani,L.D.
2013. Molecular cloning and biochemical characterization of the first Na+-channel alpha-type toxin peptide (Acra4) from Androctonus crassicauda scorpion venom Biochimie, 95, 1216-1222.
Garcia,F. Villegas,E. Espino-Solis,G.P. Rodriguez,A. Paniagua-Solis,J.F. Sandoval-Lopez,G. Possani,L.D. Corzo,G.
2013.
Antimicrobial peptides from arachnid venoms and their microbicidal activity in the presence of commercial antibiotics J Antibiot.(Tokyo), 66, 3-10.
Caliskan,F. Garcia,B.I. Coronas,F.I. Restano-Cassulini,R. Korkmaz,F. Sahin,Y. Corzo,G. Possani,L.D.
2012. Purification and cDNA cloning of a novel neurotoxic peptide (Acra3) from the scorpion Androctonus crassicauda Peptides, 37, 106-112.
Ramirez-Carreto,S. Quintero-Hernandez,V. Jimenez-Vargas,J.M. Corzo,G. Possani,L.D. Becerril,B. Ortiz,E.
2012. Gene cloning and functional characterization of four novel antimicrobial-like peptides from scorpions of the family Vaejovidae Peptides, 34, 290-295.
Saucedo,A.L. Del Rio F. Picco,C. Estrada,G. Prestipino,G. Possani,L.D. Delepierre,M. Corzo,G.
2012. Solution structure of native and recombinant expressed toxin CssII from the venom of the scorpion suffusus, and their effects on Nav1.5 Sodium channels Biochimica et Biophysica Acta (BBA), 1824, 478-487.
Schiavon,E. Pedraza-Escalona,M. Gurrola,G.B. Olamendi-Portugal,T. Corzo,G. Wanke,E. Possani,L.D.
2012. Negative-shift activation, current reduction and resurgent currents induced by beta-toxins from Centruroides scorpions in sodium channels Toxicon, 59, 283-293.
Quintero-Hernandez,V. Ortiz,E. Rendon,M.R. Schwartz,E.F. Becerril,B. Corzo,G. Possani,L.D.
2011. Scorpion and spider venom peptides: Gene cloning and peptide expression Toxicon, 58, 644-663.
Espino-Solis,G.P. Estrada,G. Olamendi-Portugal,T. Villegas,E. Zamudio,F. Cestele,S. Possani,L.D. Corzo,G.
2011. Isolation and molecular cloning of beta-neurotoxins from the venom of the scorpion Centruroides suffusus suffusus Toxicon, 57, 739-746.
Riano-Umbarila,L. Contreras-Ferrat,G. Olamendi-Portugal,T. Morelos-Juarez,C. Corzo,G. Possani,L.D. Becerril,B.
2011. Exploiting cross-reactivity to neutralize two different scorpion venoms with one single-chain antibody fragment J Biol Chem, 286, 6143-6151.
Estrada,G. Restano-Cassulini,R. Ortiz,E. Possani,L.D. Corzo,G.
2011. Addition of positive charges at the C-terminal peptide region of CssII; a mammalian scorpion peptide toxin; improves its affinity for sodium channels Nav1.6 Peptides, 32, 75-79 (Correction vol 32 p.1096).
Corrales-Garcia,L.L. Possani,L.D. Corzo,G.
2011. Expression systems of human beta-defensins: vectors, purification and biological activities Amino Acids, 40, 5-13.
Rodriguez,A. Villegas,E. Satake,H. Possani,L.D. Corzo,G.
2011.
Amino acid substitutions in an alpha-helical antimicrobial arachnid peptide affect its chemical properties and biological activity towards pathogenic bacteria but improves its therapeutic index Amino Acids, 40, 61-68.
Yamaji,N. Little,M.J. Nishio,H. Billen,B. Villegas,E. Nishiuchi,Y. Tytgat,J. Nicholson,G.M. Corzo,G.
2009.
Synthesis, solution structure and phyla-selectivity of a spider {delta}-toxin that slows inactivation of specific voltage-gated sodium channel subtypes J Biol Chem, 284, 24568-24582.
Corzo,G. Prochnicka-Chalufour,A. Garcia,B.I. Possani,L.D. Delepierre,M.
2009.
Solution structure of Cn5, a crustacean toxin found in the venom of the scorpions Centruroides noxius and Centruroides suffusus suffusus Biochimica et Biophysica Acta-Proteins and Proteomics, 1794, 1591-1598.
Hernandez-Salgado,K. Estrada,G. Olvera,A. Coronas,F.I. Possani,L.D. Corzo,G.
2009.
Heterologous expressed toxic and non-toxic peptide variants of toxin CssII are capable to produce neutralizing antibodies against the venom of the scorpion Centruroides suffusus suffusus Immunol Lett, 125, 93-99.
Corzo,G. Bernard,C. Clement,H. Villegas,E. Bosmans,F. Tytgat,J. Possani,L.D. Darbon,H. Alagon,A.
2009.
Insecticidal peptides from the theraposid spider Brachypelma albiceps: A NMR-based model of Ba2 Biochimica et Biophysica Acta (BBA), 1794, 1190-1196.
Prestipino,G. Corzo,G. Romeo,S. Murgia,A.R. Zanardi,I. Gurrola,G. Possani,L.D.
2009.
Scorpion toxins that block transient currents (IA) of rat cerebellum granular cells Toxicology Letters, 187, 1-9.
Hernandez-Campuzano,B. Suarez,R. Lina,L. Hernandez,V. Villegas,E. Corzo,G. Iturriaga,G.
2009.
Expression of a spider venom peptide in transgenic tobacco confers insect resistance Toxicon, 53, 122-128.
Rodriguez de la Vega,R.C. Corzo,G. Possani,L.D. 2013. Scorpion Venoms as a Platform for Drug Development en: Guccione,S. Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics. Cambridge. Royal Society of Chemistry. in press
D'Suze,G. Corzo Burguete,G. Paniagua Solis,J.F. 2011. Emergencias por Animales Ponzonosos en las Americas. Mexico:. Instituto Bioclon.
Corzo,G.
2011. Determinantes Moleculares de las Neurotoxinas de Arácnidos Implicados en la Unión a los Canales de Sodio Dependientes de Voltaje Mensaje Bioquimico, 35, 131-142.
Alagon-Cano,A. Corzo,G. Clement-Carretero,H. Garcia-Garcia,F.
2010. Arañas: venenos con potencial biotecnológico. Hypatia, 33, .
Barraza, G. , Clement, H. , Corzo. G. 2011 Un nuevo péptido analgésico proveniente del veneno de la araña Brachypelma verdezy.UNAM México. (en trámite)
Corzo G. , Garcia F. , Possani L.D. , Villegas E. 2011 Uso de un peptido antibiotico proveniente del veneno del alacran Centruroides suffusus suffusus y sus composiciones farmaceuticas obtenidas con antibioticos comerciales.UNAM México. (en trámite)
G.A.Corzo-Burguete, G. Estrada-Tapia, K. Hernández-Salgado, B. I. García-Gómez y L. D. Possani P 2008 Inmunógenos recombinantes para la producción de antivenenos contra el veneno de alacranes del género Centruroides.UNAM México. (en trámite)
Corzo, G., Estrada. G. , Hernandez, K. , Garcia B.I. , Possani. L.D 2008 Variantes recombinantes de una toxina del veneno del alacrán Centruroides sufussus sufussus para la producción de antivenenos contra el veneno de alacranes del género Centruroides.UNAM México.
G. Corzo P. Escoubas 2002 Insecticidal peptides and methods for use of same. World Intellectual Property Organization.
G. Corzo P. Escoubas 2002 Insecticidal peptides and methods for use of same. Estados Unidos.
G. Corzo T. Nakajima 2002 Novel assassin bug peptides having calcium channel. Japan Patent Office.
G. Corzo E. Villegas y T Nakajima 2001 Antimicrobial peptides from venom of scorpions. Japan Patent Office.
Líder Académico »»