Instituto de Biotecnologia UNAM

IBT-UNAM : Dr. Fidel Alejandro Sanchez Flores

Dr.

Dr. Fidel Alejandro Sanchez Flores


Encargado de la U. Universitaria de Apoyo Bioinformático

Investigador

email: alexsf@ibt.unam.mx

Teléfonos

Oficina +52 (777) 329-1864
desde la CDMX 562-27864

red UNAM 27864

Laboratorio +52 (777) 329-1777 ext 38151.
desde la CDMX 562-27777 ext 38151

red UNAM 38151


- Licenciatura: Investigación Biomédica Básica, IIB-UNAM (2001)
- Doctorado: Ciencias Bioquímicas, IBT-UNAM (2007) con especialidad en Bioinformática
- Estancia de Investigación: Postdoctoral Proyecto del genoma de Taenia solium, UNAM (2007-2008)
- Estancia de Investigación: Postdoctoral Wellcome Trust Sanger Insitute, Cambridge, UK (2009-2011)


Estudiantes

Biol. Jose Santiago Sanchez

Publicaciones recientes

Garcia,C.F. Pedrini,N. Sanchez-Paz,A. Reyna-Blanco,C.S. Lavarias,S. Muhlia-Almazan,A. Fernandez-Gimenez,A. Laino,A. de-la-Re-Vega,E. Lukaszewicz,G. Lopez-Zavala,A.A. Brieba,L.G. Criscitello,M.F. Carrasco-Miranda,J.S. Garcia-Orozco,K.D. Ochoa-Leyva,A. Rudino-Pinera,E. Sanchez-Flores,A. Sotelo-Mundo,R.R. 2017. De novo assembly and transcriptome characterization of the freshwater prawn Palaemonetes argentinus: Implications for a detoxification response Marine Genomics, Sep 8 [Epub ahead of print], .

Sandoval-Azuara,S.E. Perea-Jacobo,R. Muniz-Salazar,R. Robbe-Austerman,S. Perera-Ortiz,A. Lopez-Valencia,G. Bravo,D.M. Sanchez-Flores,A. Miranda-Guzman,D. Flores-Lopez,C.A. Zenteno-Cuevas,R. Laniado-Laborin,R. Lafarga de la,C.F. Stuber,T.P. 2017. Whole genome sequencing of Mycobacterium bovis to obtain molecular fingerprints in human and cattle isolates from Baja California, Mexico International Journal of Infectious Diseases, 63, 48-56.

Rodriguez-Anaya,L.Z. Ibarra-Gamez,J.C. Lares-Villa,F. Casillas-Hernandez,R. Sanchez-Flores,A. Gonzalez-Galaviz,J.R. 2016. Analysis of repeated compound units in ORF94 of white spot syndrome virus isolated from Litopenaeus vannamei from outbreak and non-outbreak shrimp farms in Sonora, Mexico Latin American Journal of Aquatic Research, 44, 850-854.

Ramirez-Puebla,S.T. Ormeno-Orrillo,E. Vera-Ponce de Leon A. Lozano,L. Sanchez-Flores,A. Rosenblueth,M. Martinez-Romero,E. 2016. Genomes of Candidatus Wolbachia bourtzisii wDacA and Candidatus Wolbachia pipientis wDacB from the Cochineal Insect Dactylopius coccus (Hemiptera: Dactylopiidae) G3: Genes, Genomes, Genetics, 6, 3343-3349.

Sanchez-Flores,A. Penazola,F. Carpinteyro-Ponce,J. Nazario-Yepiz,N. Abreu-Goodger,C. Machado,C.A. Markow,T.A. 2016. Genome Evolution in Three Species of Cactophilic Drosophila G3: Genes, Genomes, Genetics, 6, 3097-3105.

Vera-Ponce De Leon,A. Sanchez-Flores,A. Rosenblueth,M. Martinez-Romero,E. 2016. Fungal Community Associated with Dactylopius (Hemiptera: Coccoidea: Dactylopiidae) and Its Role in Uric Acid Metabolism Frontiers in Microbiology, 7, 954.

Bedoya-Lopez,A. Estrada,K. Sanchez-Flores,A. Ramirez,O.T. Altamirano,C. Segovia,L. Miranda-Rios,J. Trujillo-Roldan,M.A. Valdez-Cruz,N.A. 2016. Effect of Temperature Downshift on the Transcriptomic Responses of Chinese Hamster Ovary Cells Using Recombinant Human Tissue Plasminogen Activator Production Culture PLoS ONE, 11, e0151529.

Escobar-Zepeda,A. Sanchez-Flores,A. Quirasco Baruch,M. 2016. Metagenomic analysis of a Mexican ripened cheese reveals a unique complex microbiota Food Microbiology, 57, 116-127.

Rodriguez-Anaya,L.Z. Gonzalez-Galaviz,J.R. Casillas-Hernandez,R. Lares-Villa,F. Estrada,K. Ibarra-Gamez,J.C. Sanchez-Flores,A. 2016. Draft Genome Sequence of White Spot Syndrome Virus Isolated from Cultured Litopenaeus vannamei in Mexico Genome Announcements, 4, .

Hunt,V.L. Tsai,I.J. Coghlan,A. Reid,A.J. Holroyd,N. Foth,B.J. Tracey,A. Cotton,J.A. Stanley,E.J. Beasley,H. Bennett,H.M. Brooks,K. Harsha,B. Kajitani,R. Kulkarni,A. Harbecke,D. Nagayasu,E. Nichol,S. Ogura,Y. Quail,M.A. Randle,N. Xia,D. Brattig,N.W. Soblik,H. Ribeiro,D.M. Sanchez-Flores,A. Hayashi,T. Itoh,T. Denver,D.R. Grant,W. Stoltzfus,J.D. Lok,J.B. Murayama,H. Wastling,J. Streit,A. Kikuchi,T. Viney,M. Berriman,M. 2016. The genomic basis of parasitism in the Strongyloides clade of nematodes Nature Genetics, 48, 299-307.

Escobar-Zepeda,A. Vera-Ponce De Leon,A. Sanchez-Flores,A. 2015. The road to metagenomics: from microbiology to DNA sequencing technologies and bioinformatics Frontiers in Genetics, 6, .

Olvera-Garcia,M. Fontes-Perez,H. Chavez-Martinez,A. Ruiz-Barrera O. Rodriguez-Almeida,F.A. Sanchez-Flores,A. Corral-Luna,A. 2015. Draft Genome Sequences for Five Strains of Trabulsiella odontotermitis, Isolated from Heterotermes sp. Termite Gut Genome Announcements, 3, art. no. e0128915.

Fontes-Perez,H. Olvera-Garcia,M. Chavez-Martinez,A. Rodriguez-Almeida,F.A. Arzola-Alvarez,C.A. Sanchez-Flores,A. Corral-Luna,A. 2015. Genome Sequence of Citrobacter sp. CtB7.12, Isolated from the Gut of the Desert Subterranean Termite Heterotermes aureus Genome Announcements, 3, art. no. e0129015.

Velez,P. Alejandri-Ramirez,N.D. Gonzalez,M.C. Estrada,K.J. Sanchez-Flores,A. Dinkova,T.D. 2015. Comparative Transcriptome Analysis of the Cosmopolitan Marine Fungus Corollospora maritima Under Two Physiological Conditions G3: Genes, Genomes, Genetics, 5, 1805-1814.

Gomez-Angulo,J. Vega-Alvarado,L. Escalante-Garcia,Z. Grande,R. Gschaedler-Mathis,A. Amaya-Delgado,L. Arrizon,J. Sanchez-Flores,A. 2015. Genome Sequence of Torulaspora delbrueckii NRRL Y-50541, Isolated from Mezcal Fermentation Genome Announcements, 3, .

Calva,E. Silva,C. Zaidi,M.B. Sanchez-Flores,A. Estrada,K. Silva,G.G. Soto-Jimenez,L.M. Wiesner,M. Fernandez-Mora,M. Edwards,R.A. Vinuesa,P. 2015. Complete Genome Sequencing of a Multidrug-Resistant and Human-Invasive Salmonella enterica Serovar Typhimurium Strain of the Emerging Sequence Type 213 Genotype Genome Announcements, 3, e00663-15.

Vega-Alvarado,L. Gomez-Angulo,J. Escalante-Garcia,Z. Grande,R. Gschaedler-Mathis,A. Amaya-Delgado,L. Sanchez-Flores,A. Arrizon,J. 2015. High-Quality Draft Genome Sequence of Candida apicola NRRL Y-50540 Genome Announcements, 3, [correction en vol 3 (4) 2015].

Valencia-Morales,M.P. Zaina,S. Heyn,H. Carmona,F.J. Varol,N. Sayols,S. Condom,E. Ramirez-Ruz,J. Gomez,A. Moran,S. Lund,G. Rodriguez-Rios,D. Lopez-Gonzalez,G. Ramirez-Nava,M. de la Rocha C. Sanchez-Flores,A. Esteller,M. 2015. The DNA methylation drift of the atherosclerotic aorta increases with lesion progression BMC Medical Genomics, 8, 85.

Dautt-Castro,M. Ochoa-Leyva,A. Contreras-Vergara,C.A. Pacheco-Sanchez,M.A. Casas-Flores,S. Sanchez-Flores,A. Kuhn,D.N. Islas-Osuna,M.A. 2015. Mango (Mangifera indica L.) cv. Kent fruit mesocarp de novo transcriptome assembly identifies gene families important for ripening Frontiers in Plant Science, 6, .

Glover,L. Alsford,S. Baker,N. Turner,D.J. Sanchez-Flores,A. Hutchinson,S. Hertz-Fowler,C. Berriman,M. Horn,D. 2015. Genome-scale RNAi screens for high-throughput phenotyping in bloodstream-form African trypanosomes Nature Protocols, 10, 106-133.

Ghaffari,N. Sanchez-Flores,A. Doan,R. Garcia-Orozco,K.D. Chen,P.L. Ochoa-Leyva,A. Lopez-Zavala,A.A. Carrasco,J.S. Hong,C. Brieba,L.G. Rudino-Pinera,E. Blood,P.D. Sawyer,J.E. Johnson,C.D. Dindot,S.V. Sotelo-Mundo,R.R. Criscitiello,M.F. 2014. Novel transcriptome assembly and improved annotation of the whiteleg shrimp (Litopenaeus vannamei), a dominant crustacean in global seafood mariculture Scientific Reports, 4, 7081.

Cuesta,I. Gonzalez,L.M. Estrada,K. Grande,R. Zaballos,A. Lobo,C.A. Barrera,J. Sanchez-Flores,A. Montero,E. 2014. High-Quality Draft Genome Sequence of Babesia divergens, the Etiological Agent of Cattle and Human Babesiosis Genome Announcements, 2, .

Reid,A.J. Blake,D.P. Ansari,H.R. Billington,K. Browne,H.P. Bryant,J.M. Dunn,M. Hung,S.S. Kawahara,F. Miranda-Saavedra,D. Malas,T. Mourier,T. Naghra,H. Nair,M. Otto,T.D. Rawlings,N.D. Rivailler,P. Sanchez-Flores,A. Sanders,M. Subramaniam,C. Tay,Y.L. Woo,Y. Wu,X. Barrell,B. Dear,P.H. Doerig,C. Gruber,A. Ivens,A.C. Parkinson,J. Rajandream,M.A. Shirley,M.W. Wan,K.L. Berriman,M. Tomley,F.M. Pain,A. 2014. Genomic analysis of the causative agents of coccidiosis in domestic chickens Genome Research, 24, 1676-1685.

Sotillo,J. Sanchez-Flores,A. Cantacessi,C. Harcus,Y. Pickering,D. Bouchery,T. Camberis,M. Tang,S.C. Giacomin,P. Mulvenna,J. Mitreva,M. Berriman,M. LeGros,G. Maizels,R.M. Loukas,A. 2014. Secreted proteomes of different developmental stages of the gastrointestinal nematode Nippostrongylus brasiliensis Molecular and Cellular Proteomics, 13, 2736-2751 * .

Oliveira,P.D. Lima,F.M. Cruz,M.C. Ferreira,R.C. Sanchez-Flores,A. Cordero,E.M. Cortez,D.R. Ferreira,E.R. Briones,M.R. Mortara,R.A. Silveira,J.F. Bahia,D. 2014. Trypanosoma cruzi: Genome characterization of phosphatidylinositol kinase gene family (PIK and PIK-related) and identification of a novel PIK gene Infection, Genetics and Evolution, 25, 157-165.

Sanchez-Flores,A. Abreu-Goodger,C. 2014. A Practical Guide to Sequencing Genomes and Transcriptomes Current Topics in Medicinal Chemistry, 14, 398-406.

Soto-Jimenez,L.M. Estrada,K. Berriman,M. Sanchez-Flores,A. 2014. GARM: Genome Assembly, Reconciliation and Merging pipeline Current Topics in Medicinal Chemistry, 14, 418-424.

Tsai,I.J. Zarowiecki,M. Holroyd,N. Garciarrubio,A. Sanchez-Flores,A. Brooks,K.L. Tracey,A. Bobes,R.J. Fragoso,G. Sciutto,E. Aslett,M. Beasley,H. Bennett,H.M. Cai,J. Camicia,F. Clark,R. Cucher,M. De Silva,N. Day,T.A. Deplazes,P. Estrada,K. Fernandez,C. Holland,P.W.H. Hou,J. Hu,S. Huckvale,T. Hung,S.S. Kamenetzky,L. Keane,J.A. Kiss,F. Koziol,U. Lambert,O. Liu,K. Luo,X. Luo,Y. Macchiaroli,N. Nichol,S. Paps,J. Parkinson,J. Pouchkina-Stantcheva,N. Riddiford,N. Rosenzvit,M. Salinas,G. Wasmuth,J.D. Zamanian,M. Zheng,Y. Cai,X. Soberon,X. Olson,P.D. Laclette,J.P. Brehm,K. Berriman,M. Ochoa-Leyva,A. 2013. The genomes of four tapeworm species reveal adaptations to parasitism Nature, 496, 57-63.

Sanchez-Flores,A. 2013. Setting the foundation for helminths systems biology: Sequencing technologies, methodologies and applications Systems Biomedicine, 1, 5-11.

Libros y capítulos recientes

Sanchez-Flores,F. 2016. Secuenciacion masiva en la era genomica en: Ramirez-Bello,J. Genómica estructural y funcional en las enfermedades multifactoriales. UNAM.


Divulgación

Jimenez-Jacinto,V. Escobar-Zepeda,A. Godoy,E. Vega-Alvarado,L. Verleyen,J. Estrada,K. Sanchez-Flores,A. 2017. El metagenoma del taco Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 8, 29-32.

Sanchez-Flores,A. 2015. Unidad de Secuenciación Masiva y Bioinformática, a la vanguardia de la ciencia Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 2, 23-24.

Sanchez-Flores,A. 2015. Las nuevas tecnologías y el cómputo nos ayudan a estudiar detalladamente a los patógenos Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 2, 3-4.

* Indica publicación con otra institución de adscripción



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