Instituto de Biotecnologia UNAM

IBT-UNAM : Dr. Enrique Rudiño Piñera

Dr.

Dr. Enrique Rudiño Piñera


Secretario Académico

Líder Académico »» Grupo

Investigador

Tutor de Maestría y Doctorado

Nivel III del SNI

Líneas de investigación

email: rudino@ibt.unam.mx

Teléfonos

Oficina (52+55) 562-27673 ;

Oficina +52 (777) 329-1616
desde la CDMX 562-27616

red UNAM 27616
+52 (777) 311-4900 ext 246

Laboratorio +52 (777) 329-1610
desde la CDMX 562-27610

red UNAM 27610
+52 (777) 311-4900 ext 246


- Licenciatura: Química, Universidad La Salle, A.C. (1994)
- Maestría: Biotecnología, Facultad de Química, UNAM (1999)
- Doctorado: Ciencias (Bioquímicas), IBT, UNAM (2001)
- Medalla de plata Alfonso Caso (generación 1995)
- Laboratory of Molecular Biophysics, University of Oxford, Reino Unido (2003-2004) Visiting Scientist Fellowship from Royal Society, U.K. (2006)


Estudiantes

Lic. Ulises Dantán

Biol. Victor Hugo Cifuentes

Angela Escudero

M.C. Yasel Guerra

Biol. Nizaa Jimenez

Biol. Arisbeth Almeida

Lic. Jesús Lara

Biol. Elena Lizbeth Garcia

M.C. Yerli Marín

M.C. Ariadna Berenice Juarez

Ing. Alexis Omar Campuzano

Lic. Francisco Murphy

M.C Ruben Priego

Q.B.P. Alberto Venancio

Alfredo Rodríguez

M.C. Ricardo Miranda

Publicaciones recientes

Garcia,C.F. Pedrini,N. Sanchez-Paz,A. Reyna-Blanco,C.S. Lavarias,S. Muhlia-Almazan,A. Fernandez-Gimenez,A. Laino,A. de-la-Re-Vega,E. Lukaszewicz,G. Lopez-Zavala,A.A. Brieba,L.G. Criscitello,M.F. Carrasco-Miranda,J.S. Garcia-Orozco,K.D. Ochoa-Leyva,A. Rudino-Pinera,E. Sanchez-Flores,A. Sotelo-Mundo,R.R. 2017. De novo assembly and transcriptome characterization of the freshwater prawn Palaemonetes argentinus: Implications for a detoxification response Marine Genomics, Sep 8 [Epub ahead of print], .

Jimenez-Sandoval,P. Vique-Sanchez,J.L. Hidalgo,M.L. Velazquez-Juarez,G. Diaz-Quezada,C. Arroyo-Navarro,L.F. Moran,G.M. Fattori,J. Jessica Diaz-Salazar,A. Rudino-Pinera,E. Sotelo-Mundo,R. Figueira,A.C.M. Lara-Gonzalez,S. Benitez-Cardoza,C.G. Brieba,L.G. 2017. A competent catalytic active site is necessary for substrate induced dimer assembly in triosephosphate isomerase Biochimica et Biophysica Acta (BBA), 1865, 1423-1432.

Campos-Acevedo,A.A. Sotelo-Mundo,R.R. Perez,J. Rudino-Pinera,E. 2017. Is dimerization a common feature in thioredoxins? The case of thioredoxin from Litopenaeus vannamei Acta Crystallographica Section D, 73, 326-339.

Valenzuela-Chavira,I. Contreras-Vergara,C.A. Arvizu-Flores,A.A. Serrano-Posada,H. Lopez-Zavala,A.A. Garcia-Orozco,K.D. Hernandez-Paredes,J. Rudino-Pinera,E. Stojanoff,V. Sotelo-Mundo,R.R. Islas-Osuna,M.A. 2017. Insights into ligand binding to a glutathione S-transferase from mango: Structure, thermodynamics and kinetics Biochimie, 135, 35-45.

Ayala-Sumuano,J.T. Licea-Navarro,A. Rudino-Pinera,E. Rodriguez,E. Rodriguez-Almazan,C. 2017. Sequencing and de novo transcriptome assembly of Anthopleura dowii Verrill (1869), from Mexico Genomics Data, 11, 92-94.

Juarez-Martinez,A.B. Sotelo-Mundo,R.R. Rudino-Pinera,E. 2017. Crystal structure of a class-mu glutathione S-transferase from whiteleg shrimp Litopenaeus vannamei: structural changes in the xenobiotic binding H-site may alter the spectra of molecules bound J Biochem Mol Toxicol, 31, e21838.

Campos-Acevedo,A.A. Diaz-Vilchis,A. Sotelo-Mundo,R.R. Rudino-Pinera,E. 2016. First attempts to crystallize a non-homogeneous sample of thioredoxin from Litopenaeus vannamei: What to do when you have diffraction data of a protein that is not the target? Biochemistry and Biophysics Reports, 8, 284-289.

Venancio-Landeros,A.A. Rudino-Pinera,E. Cardona-Felix,C.S. 2016. Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans Biochemistry and Biophysics Reports, 8, 200-206.

Lopez-Zavala,A.A. Carrasco-Miranda,J.S. Ramirez-Aguirre,C.D. Lopez-Hidalgo,M. Benitez-Cardoza,C.G. Ochoa-Leyva,A. Cardona-Felix,C.S. Diaz-Quezada,C. Rudino-Pinera,E. Sotelo-Mundo,R.R. Brieba,L.G. 2016. Structural insights from a novel invertebrate triosephosphate isomerase from Litopenaeus vannamei Biochimica et Biophysica Acta (BBA) Proteins and Proteomics, 1864, 1696-1706.

Guerra,Y. Valiente,P.A. Pons,T. Berry,C. Rudino-Pinera,E. 2016. Structures of a bi-functional Kunitz-type STI family inhibitor of serine and aspartic proteases: could the aspartic protease inhibition have evolved from a canonical serine protease-binding loop? Journal of Structural Biology, 195, 259-271.

Rudino-Pinera,E. Stojanoff,V. 2016. Editorial: Synchrotron Applications in Life Sciences Protein And Peptide Letters, 23, 200.

Riano-Umbarila,L. Ledezma-Candanoza,L.M. Serrano-Posada,H. Fernandez-Taboada,G. Olamendi-Portugal,T. Rojas-Trejo,S. Gomez-Ramirez,I.V. Rudino-Pinera,E. Possani,L.D. Becerril,B. 2016. Optimal neutralization of Centruroides noxius venom is understood through a structural complex between two antibody fragments and the Cn2 toxin Journal of Biological Chemistry, 291, 1619-1630.

Serrano-Posada,H. Centeno-Leija,S. Rojas-Trejo,S.P. Rodriguez-Almazan,C. Stojanoff,V. Rudino-Pinera,E. 2015. X-ray-induced catalytic active-site reduction of a multicopper oxidase: structural insights into the proton-relay mechanism and O2-reduction states Acta Crystallographica Section D, 71, 2396-2411.

Serrano-Posada,H. Centeno-Leija,S. Rojas-Trejo,S. Stojanoff,V. Rodriguez-Sanoja,R. Rudino-Pinera,E. Sanchez,S. 2015. Crystallization and X-ray diffraction analysis of a putative bacterial class I labdane-related diterpene synthase Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 71, 1194-1199.

Villalba,M.I. Canul-Tec,J.C. Luna-Martinez,O.D. Sanchez-Alcala,R. Olamendi-Portugal,T. Rudino-Pinera,E. Rojas,S. Sanchez-Lopez,R. Fernandez-Velasco,D.A. Becerril,B. 2015. Site-directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human lambda3r Light Chains Journal of Biological Chemistry, 290, 2577-2592 [Correction vol 290 p 13039].

Campos-Acevedo,A.A. Rudino-Pinera,E. 2014. Crystallographic Studies Evidencing the High Energy Tolerance to Disrupting the Interface Disulfide Bond of Thioredoxin 1 from White Leg Shrimp Litopenaeus vannamei Molecules, 19, 21113-21126.

Lopez-Falcon,B. Meyer-Nava,S. Hernandez-Rodriguez,B. Campos,A. Montero,D. Rudino,E. Vazquez,M. Zurita,M. Valadez-Graham,V. 2014. Characterization of the Drosophila Group Ortholog to the Amino-Terminus of the Alpha-Thalassemia and Mental Retardation X-Linked (ATRX) Vertebrate Protein PLoS ONE, 9, e113182 [correction in 2016 Feb 10;11(2):e0149367].

Ghaffari,N. Sanchez-Flores,A. Doan,R. Garcia-Orozco,K.D. Chen,P.L. Ochoa-Leyva,A. Lopez-Zavala,A.A. Carrasco,J.S. Hong,C. Brieba,L.G. Rudino-Pinera,E. Blood,P.D. Sawyer,J.E. Johnson,C.D. Dindot,S.V. Sotelo-Mundo,R.R. Criscitiello,M.F. 2014. Novel transcriptome assembly and improved annotation of the whiteleg shrimp (Litopenaeus vannamei), a dominant crustacean in global seafood mariculture Scientific Reports, 4, 7081.

Lopez-Zavala,A.A. Quintero-Reyes,I.E. Carrasco-Miranda,J.S. Stojanoff,V. Weichsel,A. Rudino-Pinera,E. Sotelo-Mundo,R.R. 2014. Structure of nucleoside diphosphate kinase from pacific shrimp (Litopenaeus vannamei) in binary complexes with purine and pyrimidine nucleoside diphosphates Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 70, 1150-1154.

Carrasco-Miranda,J.S. Lopez-Zavala,A.A. Arvizu-Flores,A.A. Garcia-Orozco,K.D. Stojanoff,V. Rudino-Pinera,E. Brieba,L.G. Sotelo-Mundo,R.R. 2014. Crystal Structure of the Shrimp Proliferating Cell Nuclear Antigen: Structural Complementarity with WSSV DNA Polymerase PIP-Box PLoS ONE, 9, e94369.

Bello,M. Correa-Basurto,J. Rudino-Pinera,E. 2014. Simulation of the cavity-binding site of three bacterial multicopper oxidases upon complex stabilization: interactional profile and electron transference pathways Journal of Biomolecular Structure and Dynamics, 32, 1303-1317.

Lopez-Zavala,A.A. Garcia-Orozco,K.D. Carrasco-Miranda,J.S. Sugich-Miranda,R. Velazquez-Contreras,E.F. Criscitiello,M.F. Brieba,L.G. Rudino-Pinera,E. Sotelo-Mundo,R.R. 2013. Crystal structure of shrimp arginine kinase in binary complex with arginine-a molecular view of the phosphagen precursor binding to the enzyme Journal of Bioenergetics and Biomembranes, 45, 511-518.

Zarate-Romero,A. Stojanoff,V. Rojas-Trejo,S.P. Hansberg,W. Rudino-Pinera,E. 2013. Conformational stability and crystal packing: polymorphism in Neurospora crassa CAT-3 Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69, 753-758.

Campos-Acevedo,A.A. Garcia-Orozco,K.D. Sotelo-Mundo,R.R. Rudino-Pinera,E. 2013. Expression, purification, crystallization and X-ray crystallographic studies of different redox states of the active site of thioredoxin 1 from the whiteleg shrimp Litopenaeus vannamei Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 69, 488-493.

Salazar-Medina,A.J. Sugich-Miranda,R. Teran-Cabanillas,E. Hernandez,J. Gonzalez-Aguilar,G.A. Rudino-Pinera,E. Sotelo-Mundo,R.R. Velazquez-Contreras,E.F. 2013. Antioxidant Capacity of Two Novel Bioactive Fe(III)-Cyclophane Complexes Molecules, 18, 1762-1774.


Divulgación

Antillon,A. de la Rosa,G. Juarez,A. Moreno,M. Mustre,J. Napsuciale,M. Rudino,E. 2011. First Mexican Synchrotron Radiation Users Meeting Synchrotron Radiation News, 24, 2-5.

de la Mora-Lugo,E. Rudino-Pinera,E. 2008. Cristales, difracción y desplazamientos atómicos: ¿es posible usar datos cristalográficos para extraer movimientos moleculares en proteínas? Mensaje Bioquimico, 32, 135-148.

* Indica publicación con otra institución de adscripción



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