Instituto de Biotecnologia UNAM

IBT-UNAM : Dr. Adrian Ochoa Leyva

Dr.

Dr. Adrian Ochoa Leyva


Coordinador de Licenciatura

Líder Académico »» Grupo

Investigador

Coordinación General de Docencia

Líneas de investigación

email: aochoa@ibt.unam.mx

Teléfonos


Oficina +52 (777) 329-1614
desde la CDMX 562-27614

red UNAM 27614

Laboratorio +52 (777) 329-1668
desde la CDMX 562-27668

red UNAM 27668


- Licenciatura: Licenciatura: Biólogo Experimental, Universidad Autónoma de Sinaloa (2005)
- Maestría: Ciencias Bioquímicas, Instituto de Biotecnología-UNAM (2007)
- Doctorado: Ciencias Bioquímicas, Instituto de Biotecnología-UNAM (2011)
- Estancia de Investigación: University of Warwick (2007)
- Estancia de Investigación: Institute for Systems Biology (2011)
- Estancia postdoctoral Instituto Nacional de Medicina Genómica (2011-2013)


Estudiantes

Ing. Juan Pablo Ochoa

Ing. Erendira Marlene Parra

Q.F.B. Marco Antonio Jimenez

Biol. Melany Josheline Cervantes

M.C. Leonardo Yame Fox

Itzel Abigail Hernández "Impacto de los bacteriófagos asociados a la obesidad infantil en el metagenoma y metatranscriptoma intestinal"

Lic. Juan Manuel Hernandez

Maria Fernanda Cornejo

Q.F.B. Miriam Leonardo

Biol. Luigui Michel Gallardo

Shirley Bikel

Q. Edgar Axel Donjuan

Publicaciones recientes

Castro-Torres,E. Jimenez-Sandoval,P. Fernandez-de,G.E. Lopez-Castillo,M. Baruch-Torres,N. Lopez-Hidalgo,M. Peralta-Castro,A. Diaz-Quezada,C. Sotelo-Mundo,R.R. Benitez-Cardoza,C.G. Espinoza-Fonseca,L.M. Ochoa-Leyva,A. Brieba,L.G. 2018. Structural Basis for the Limited Response to Oxidative and Thiol-Conjugating Agents by Triosephosphate Isomerase From the Photosynthetic Bacteria Synechocystis Frontiers in Molecular Biosciences, 5, 103.

Astudillo-Melgar,F. Ochoa-Leyva,A. Utrilla,J. Huerta-Beristain,G. 2018. Bacterial diversity and population dynamics during the fermentation of palm wine from Guerrero Mexico bioRxiv, preprint posted November 29, 2018, .

Lopez-Leal,G. Cornejo-Granados,F. Hurtado-Ramirez,J.M. Mendoza-Vargas,A. Ochoa-Leyva,A. 2018. Functional and taxonomic classification of a greenhouse water drain metagenome Standards in Genomic Sciences, 13, 20.

Cornejo-Granados,F. Hurtado-Ramirez,J.M. Hernandez-Pando,R. Ochoa-Leyva,A. 2018. Secret-AAR: A web server to assess the antigenic density of proteins and homology search against bacterial and parasite secretome proteins Genomics, Oct 11 [Epub ahead of print], .

Cornejo-Granados,F. Gallardo-Becerra,L. Leonardo-Reza,M. Ochoa-Romo,J.P. Ochoa-Leyva,A. 2018. A meta-analysis reveals the environmental and host factors shaping the structure and function of the shrimp microbiota PeerJ, 6, .

Gonzalez-Felix,M.L. Gatlin,D.M. Urquidez-Bejarano,P. de la Ree-Rodriguez,C. Duarte-Rodriguez,L. Sanchez,F. Casas-Reyes,A. Yamamoto,F.Y. Ochoa-Leyva,A. Perez-Velazquez,M. 2018. Effects of commercial dietary prebiotic and probiotic supplements on growth, innate immune responses, and intestinal microbiota and histology of Totoaba macdonaldi Aquaculture, 491, 239-251.

Lopez-Zavala,A.A. Guevara-Hernandez,E. Vazquez-Lujan,L.H. Sanchez-Paz,A. Garcia-Orozco,K.D. Contreras-Vergara,C.A. Lopez-Leal,G. Arvizu-Flores,A.A. Ochoa-Leyva,A. Sotelo-Mundo,R.R. 2018. A novel thymidylate synthase from the Vibrionales, Alteromonadales, Aeromonadales, and Pasteurellales (VAAP) clade with altered nucleotide and folate binding sites PeerJ., 6, e5023.

Lopez-Contreras,B.E. Moran-Ramos,S. Villarruel-Vazquez,R. Macias-Kauffer,L. Villamil-Ramirez,H. Leon-Mimila,P. Vega-Badillo,J. Sanchez-Munoz,F. Llanos-Moreno,L.E. Canizalez-Roman,A. del Rio-Navarro,B. Ibarra-Gonzalez,I. Vela-Amieva,M. Villarreal-Molina,T. Ochoa-Leyva,A. Aguilar-Salinas,C.A. Canizales-Quinteros,S. 2018. Composition of gut microbiota in obese and normal-weight Mexican school-age children and its association with metabolic traits Pediatric Obesity, 13, 381-388.

Dautt-Castro,M. Ochoa-Leyva,A. Contreras-Vergara,C.A. Muhlia-Almazan,A. Rivera-Dominguez,M. Casas-Flores,S. Martinez-Tellez,M.A. Sanudo-Barajas,A. Osuna-Enciso,T. Baez-Sanudo,M.A. Quiroz-Figueroa,F.R. Kuhn,D.N. Islas-Osuna,M.A. 2018. Mesocarp RNA-Seq analysis of mango (Mangifera indica L.) identify quarantine postharvest treatment effects on gene expression Scientia Horticulturae, 227, 146-153.

Garcia,C.F. Pedrini,N. Sanchez-Paz,A. Reyna-Blanco,C.S. Lavarias,S. Muhlia-Almazan,A. Fernandez-Gimenez,A. Laino,A. de-la-Re-Vega,E. Lukaszewicz,G. Lopez-Zavala,A.A. Brieba,L.G. Criscitello,M.F. Carrasco-Miranda,J.S. Garcia-Orozco,K.D. Ochoa-Leyva,A. Rudino-Pinera,E. Sanchez-Flores,A. Sotelo-Mundo,R.R. 2018. De novo assembly and transcriptome characterization of the freshwater prawn Palaemonetes argentinus: Implications for a detoxification response Marine Genomics, 37, 74-81.

Bikel,S. Jacobo-Albavera,L. Sanchez-Munoz,F. Cornejo-Granados,F. Canizales-Quinteros,S. Soberon,X. Sotelo-Mundo,R.R. Del Rio-Navarro,B.E. Mendoza-Vargas,A. Sanchez,F. Ochoa-Leyva,A. 2017. A novel approach for human whole transcriptome analysis based on absolute gene expression of microarray data PeerJ., 5, e4133.

Romero-Hidalgo,S. Ochoa-Leyva,A. Garciarrubio,A. Acuna-Alonzo,V. Antunez-Arguelles,E. Balcazar-Quintero,M. Barquera-Lozano,R. Carnevale,A. Cornejo-Granados,F. Fernandez-Lopez,J.C. Garcia-Herrera,R. Garcia-Ortiz,H. Granados-Silvestre,A. Granados,J. Guerrero-Romero,F. Hernandez-Lemus,E. Leon-Mimila,P. Macin-Perez,G. Martinez-Hernandez,A. Menjivar,M. Morett,E. Orozco,L. Ortiz-Lopez,G. Perez-Villatoro,F. Rivera-Morales,J. Riveros-McKay,F. Villalobos-Comparan,M. Villamil-Ramirez,H. Villarreal-Molina,T. Canizales-Quinteros,S. Soberon,X. 2017. Demographic history and biologically relevant genetic variation of Native Mexicans inferred from whole-genome sequencing Nature Communications, 8, 1005.

Bobes,R.J. Navarrete-Perea,J. Ochoa-Leyva,A. Anaya,V.H. Hernandez,M. Cervantes-Torres,J. Estrada,K. Sanchez-Lopez,F. Soberon,X. Rosas,G. Maroni-Nunes C. Garcia-Varela,M. Sotelo-Mundo,R.R. Lopez-Zavala,A.A. Gevorkian,G. Acero,G. Laclette,J.P. Fragoso,G. Sciutto,E. 2017. Experimental and theoretical approaches to investigate the immunogenicity of Taenia solium-derived KE7 antigen Infection and Immunity, 85, e00395-17.

Cornejo-Granados,F. Lopez-Zavala,A.A. Gallardo-Becerra,L. Mendoza-Vargas,A. Sanchez,F. Vichido,R. Brieba,L.G. Viana,M.T. Sotelo-Mundo,R.R. Ochoa-Leyva,A. 2017. Microbiome of Pacific Whiteleg shrimp reveals differential bacterial community composition between Wild, Aquacultured and AHPND/EMS outbreak conditions Scientific Reports, 7, 11783.

Cornejo-Granados,F. Zatarain-Barron,Z.L. Cantu-Robles,V.A. Mendoza-Vargas,A. Molina-Romero,C. Sanchez,F. Del Pozo-Yauner,L. Hernandez-Pando,R. Ochoa-Leyva,A. 2017. Secretome Prediction of Two M. tuberculosis Clinical Isolates Reveals Their High Antigenic Density and Potential Drug Targets Frontiers in Microbiology, 8, 128.

Lopez-Zavala,A.A. Carrasco-Miranda,J.S. Ramirez-Aguirre,C.D. Lopez-Hidalgo,M. Benitez-Cardoza,C.G. Ochoa-Leyva,A. Cardona-Felix,C.S. Diaz-Quezada,C. Rudino-Pinera,E. Sotelo-Mundo,R.R. Brieba,L.G. 2016. Structural insights from a novel invertebrate triosephosphate isomerase from Litopenaeus vannamei Biochimica et Biophysica Acta (BBA) Proteins and Proteomics, 1864, 1696-1706.

Bikel,S. Valdez-Lara,A. Cornejo-Granados,F. Rico,K. Canizales-Quinteros,S. Soberon,X. Del Pozo-Yauner,L. Ochoa-Leyva,A. 2015. Combining metagenomics, metatranscriptomics and viromics to explore novel microbial interactions: towards a systems-level understanding of human microbiome Computational and Structural Biotechnology Journal, 13, 390-401.

Gomez,S. Adalid-Peralta,L. Palafox-Fonseca,H. Cantu-Robles,V.A. Soberon,X. Sciutto,E. Fragoso,G. Bobes,R.J. Laclette,J.P. Yauner,L.D. Ochoa-Leyva,A. 2015. Genome analysis of Excretory/Secretory proteins in Taenia solium reveals their Abundance of Antigenic Regions (AAR) Scientific Reports, 5, 9683 [erratum en vol 5 (12385) ].

Dautt-Castro,M. Ochoa-Leyva,A. Contreras-Vergara,C.A. Pacheco-Sanchez,M.A. Casas-Flores,S. Sanchez-Flores,A. Kuhn,D.N. Islas-Osuna,M.A. 2015. Mango (Mangifera indica L.) cv. Kent fruit mesocarp de novo transcriptome assembly identifies gene families important for ripening Frontiers in Plant Science, 6, .

Lara-Gonzalez,S. Estrella-Hernandez,P. Ochoa-Leyva,A. Portillo-Tellez,M.C. Caro-Gomez,L.A. Figueroa-Angulo,E.E. Salgado-Lugo,H. Miranda-Ozuna,J.F. Ortega-Lopez,J. Arroyo,R. Brieba,L.G. Benitez-Cardoza,C.G. 2014. Structural and thermodynamic folding characterization of triosephosphate isomerases from Trichomonas vaginalis reveals the role of destabilizing mutations following gene duplication Proteins: Structure, Function and Bioinformatics, 82, 22-33 * .

Gomez-Jimenez,S. Noriega-Orozco,L. Sotelo-Mundo,R.R. Cantu-Robles,V.A. Cobian-Guemes,A.G. Cota-Verdugo,R.G. Gamez-Alejo,L.A. Del Pozo-Yauner,L. Guevara-Hernandez,E. Garcia-Orozco,K.D. Lopez-Zavala,A.A. Ochoa-Leyva,A. 2014. High-Quality Draft Genomes of Two Vibrio parahaemolyticus Strains Aid in Understanding Acute Hepatopancreatic Necrosis Disease of Cultured Shrimps in Mexico Genome Announcements, 2, * .

Ghaffari,N. Sanchez-Flores,A. Doan,R. Garcia-Orozco,K.D. Chen,P.L. Ochoa-Leyva,A. Lopez-Zavala,A.A. Carrasco,J.S. Hong,C. Brieba,L.G. Rudino-Pinera,E. Blood,P.D. Sawyer,J.E. Johnson,C.D. Dindot,S.V. Sotelo-Mundo,R.R. Criscitiello,M.F. 2014. Novel transcriptome assembly and improved annotation of the whiteleg shrimp (Litopenaeus vannamei), a dominant crustacean in global seafood mariculture Scientific Reports, 4, 7081.

Del Pozo-Yauner,L. Wall,J.S. Gonzalez-Andrade,M. Sanchez-Lopez,R. Rodriguez-Ambriz,S.L. Perez-Carreon,J.I. Ochoa-Leyva,A. Fernandez-Velasco,D.A. 2014. The N-terminal strand modulates immunoglobulin light chain fibrillogenesis Biochemical and Biophysical Research Communications, 443, 495-499.

Libros y capítulos recientes

Pozo-Yauner,L. Becerril,B. Ochoa-Leyva,A. Rodriguez-Ambriz,S.L. Perez-Carrion,J.I. Zavala-Padilla,G. Sanchez-Lopez,R. Fernandez-Velasco,D.A. 2015. The Structural Determinants of the Immunoglobulin Light Chain Amyloid Aggregation en: Jardon-Valadez,H.E. Physical Biology of Proteins and Peptides: Theory, Experiment, and Simulation. Cham. Springer International Publishing. pags. 1-28


Divulgación

Bikel,S. Ochoa-Leyva,A. 2018. La microbiota humana, un mundo microscópico apasionante de explorar Biotecnología en Movimiento.Revista de divulgación del Instituto de Biotecnología de la UNAM, 13, 30-32.

* Indica publicación con otra institución de adscripción



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