Group of Dr. Enrique Morett
Curriculum vitae (English)
Instituto de Biotecnología
Universidad Nacional Autónoma de
Departamento de Reconocimiento Molecular y Bioestructura
Molecular Genetics (regulation of transcription initiation), Molecular
Evolution (general protein evolution and evolution of the catalitic
activity), and the like.
From top-left to bottom-right
Rene Hernandez, Technitian, Sequencing facility;
Humberto Flores, Assitant Researcher;
Lety Olvera, Technitian;
Ricardo Grande, Assitant Researcher;
Juana Ferrer, Laboratory Assistant;
Francisco Reyes, Laboratory Assistant;
Yagul Pedraza, Student;
Esmeralda Lopez, Student;
Angel Ernesto Dago, Student;
Christian Torres, Student;
Alfredo Mendoza, Student;
Emmanuel Rajan Koil, Posdoc;
Enrique Morett, myself;
Nelly Mellado, Accounts Assistant and
Mary Olvera, Technitian.
Recent papers of the group:
1. Ciria R, Abreu-Goodger C, Morett E, Merino E. (2004). GeConT: gene context analysis.
Apr 8 [Epub ahead of print].
GeConT Gene Context Tool
2. Morett E, Korbel JO, Rajan E, Saab-Rincon G, Olvera L, Olvera M, Schmidt S, Snel B, Bork P. (2003).
discovery of analogous enzymes in thiamin biosynthesis.
This paper has been commented in
Faculty of 1000
3. Chaney M, Grande R, Wigneshweraraj SR, Cannon W, Casaz P, Gallegos
Schumacher J, Jones S, Elderkin S, Dago AE, Morett E y Buck M.
Binding of Transcription Activators to the Enhancer Dependent Sigma 54
Protein in the Presence of ADP-Aluminum Fluorate.
Genes and Development
4. Juarez K. Flores H, Davila S, Olvera L, Gonzalez V. and Morett
E. (2000). Reciprocal Domain Evolution
of a Transactivator Protein in a Restricted Sequence Landscape.
Natl Acad Sci USA.97:3314-3318.
This paper has been commented in Mexico City's newspaper La
"Cuatro mil millones de años en busca de lo óptimo"
5. Grande R, Valderrama B. and Morett E. (1999). Suppression
Analysis of Positive Control Mutants of NifA Revealed two Overlapping
Promoters for rpoN in Klebsiella
J. Mol. Biol.294:291-298.
6. Barrios H, Valderrama B. and Morett E. (1999). Compilation
and Analysis of sigma-54 Dependent Promoter Sequences.
Nucleic Acids Res.27:4305-4313.
7.Morett E. and Bork, P. (1999). A Novel Transactivation
Domain in Parkin.
8.Morett E. and Bork, P. (1998). Evolution of New Protein
Function: Recombinational Enhancer Fis Originated by Horizontal Gene
Transfer from the Transcriptional Regulator NtrC.
FEBS Lett. 433:108-112.
9. Gonzalez V, Olvera L, Soberon X and Morett E (1998). In
Studies on the Positive Control of NifA: An Hydrophobic Aminoacid Patch at
the Central Domain Involved in Transcriptional Activation.
Mol Microbiol. 28:55-68.
10. Barrios H, Grande R, Olvera, L and Morett E. (1998). In
vivo Genomic footprinting and Chemical Proobing Reveal that the
Bradyrhizobium japonicum fixRnifA Promoter Region is Differentially
Occupied and Melted by two Distinct RNA Polymerase Holoenzymes.
Natl Acad Sci USA. 95:1014-1019.
11. Osuna J, Soberón X and Morett E. (1997).
A Proposed Architecture for the Central Domain of the Bacterial
Enhancer-Binding Proteins based on Secondary Structure Prediction and
Prot. Sci. 6:543-555.
12. del Rio G, Morett E and Soberon X. (1997). Did Cyclodextrin
Glycosyltransferases Evolved from alpha-Amylases?
FEBS Lett. 416:221-224.
We share this lab with Dr, Xavier Soberon, Director of the Institute. Our groups have common interest in
molecular evolution of proteins and catalysis.
The laboratory has 16 individual working benches, each one with a desk,
and several meters of lateral benches. Aditionally, the lab has five
offices, three rooms for comun equipment, a lab dedicated to work with
radioisotops, and a large bench with computers. The Institute has several
floor centrifuges, ultracentrifuges, cold rooms, temperature-controlled
rooms, a DNA synthesis unit, a polypeptide synthesis unit, an animal
house, electron and confocal microscopy facilities, dark room, central
computing unit for institutional service, etc.
The major equipment includes digital gel recording set, spectrograph,
spin vacum dryers, fume cave, steril benches, several thermocyclers,
ultrafreecers, autoclave, HPLC, automatic DNA sequencing aparatus, several
power packs, electroporators, incubators temperature-controlled baths,
analytical balances, sonicator, refrigerated bench centrifugues, microwave
ovens,several electrophoresis chambers, etc. We have several Macs, PC's
and Silicon Graphyc computers.
FPLC, AKTA (Pharmacia) for protein purification.
Automatic DNA Sequencing unit.
Lety. She controls everybody and everything in the lab.
Mary, she is in charge of preparing samples for automatic sequencing
and collaborates in directed evolution projects.
Here she is reading about reptiles, her most profound interest in life.
Ricardo finished his Ph D last July and continued in the group now as
Ricardo. It´s hard to see when he is working.
Isa, She was visiting the group. She comes from Alicante University,
Spain. She plans to come again soon!
(esa cara de espanto no es la mas usual!!)
Isa, from Choni´s Lab.
He is Angel Ernesto. He is from Cuba and he is doing his Ph D here.
Rene Hernandez. This guy is in control of our DNA Sequencer.
Some useful academic links:
And now, other interesting links.
This little guy is Andres (mi hijo) esta guapo, verdad?
A more recent picture of Andres
He´s Diego, my elder son.
Some art by Andres
Noticias de México y del Mundo
Universidad de Guadalajara.
This is the best server in
Gabriel Moreno's opinion
(he comes from
Want to know about Mexico? This is where (Culture, cuisine,
painters, and a big ETCETERA).
Access to the WebMuseum
Sunsite. Use this or the one above to find your nearest mirror.
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